Expansion of myeloid suppressor cells and suppression of Lassa virus-specific T cells during fatal Lassa fever.

Authors: Blaise Lafoux, Gustave Fourcaud, Jimmy Hortion, Laura Soyer, Alexandra Journeaux, Clara Germain, Stéphanie Reynard, Hadrien Cousseau, Clémentine Larignon, Natalia Pietrosemoli, Séverine Croze, Joël Lachuer, Emeline Perthame, Sylvain Baize

Source: PLoS Pathogens, Vol 21, Iss 4, p e1013111 (2025)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

Access URL: https://doaj.org/article/cbbbcc873fd3430d89bcae8fc25d04bc

Fatal Lassa fever in cynomolgus monkeys is associated with systemic viral dissemination and inflammation.

Authors: Jimmy Hortion, Emeline Perthame, Blaise Lafoux, Laura Soyer, Stéphanie Reynard, Alexandra Journeaux, Clara Germain, Hélène Lopez-Maestre, Natalia Pietrosemoli, Nicolas Baillet, Séverine Croze, Catherine Rey, Catherine Legras-Lachuer, Sylvain Baize

Source: PLoS Pathogens, Vol 20, Iss 12, p e1012768 (2024)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

Access URL: https://doaj.org/article/ffe5f202a4454064931948446f05f238

Targeting n-myristoyltransferases promotes a pan-Mammarenavirus inhibition through the degradation of the Z matrix protein.

Authors: Xavier Carnec, Virginie Borges-Cardoso, Stéphanie Reynard, Heinrich Kowalski, Jean-Charles Gaillard, Mathieu Mateo, Jean Armengaud, Sylvain Baize

Source: PLoS Pathogens, Vol 20, Iss 12, p e1012715 (2024)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

Access URL: https://doaj.org/article/25d31a933533497b92cc285f9433ec89

Rapid protection induced by a single-shot Lassa vaccine in male cynomolgus monkeys

Authors: Mathieu Mateo, Stéphanie Reynard, Natalia Pietrosemoli, Emeline Perthame, Alexandra Journeaux, Kodie Noy, Clara Germain, Xavier Carnec, Caroline Picard, Virginie Borges-Cardoso, Jimmy Hortion, Hélène Lopez-Maestre, Pierrick Regnard, Lyne Fellmann, Audrey Vallve, Stéphane Barron, Ophélie Jourjon, Orianne Lacroix, Aurélie Duthey, Manon Dirheimer, Maïlys Daniau, Catherine Legras-Lachuer, Caroline Carbonnelle, Hervé Raoul, Frédéric Tangy, Sylvain Baize

Source: Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/cf6be5bf89674509b73202e1f94537d5

Pathogenesis of recent Lassa virus isolates from lineages II and VII in cynomolgus monkeys

Authors: Mathieu Mateo, Jimmy Hortion, Emeline Perthame, Caroline Picard, Stéphanie Reynard, Alexandra Journeaux, Clara Germain, Xavier Carnec, Nicolas Baillet, Virginie Borges-Cardoso, Natalia Pietrosemoli, Audrey Vallve, Stéphane Barron, Ophélie Jourjon, Orianne Lacroix, Aurélie Duthey, Manon Dirheimer, Maïlys Daniau, Catherine Legras-Lachuer, Gregory Jouvion, Caroline Carbonnelle, Hervé Raoul, Sylvain Baize

Source: Virulence, Vol 13, Iss 1, Pp 654-669 (2022)

Subject Terms: Lassa virus, cynomolgus monkeys, pathogenesis, immune responses, viral hemorrhagic fevers, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: https://doaj.org/toc/2150-5594; https://doaj.org/toc/2150-5608

Access URL: https://doaj.org/article/c350a40e14234312b45ff573b2fd8f25

Systemic viral spreading and defective host responses are associated with fatal Lassa fever in macaques

Authors: Nicolas Baillet, Stéphanie Reynard, Emeline Perthame, Jimmy Hortion, Alexandra Journeaux, Mathieu Mateo, Xavier Carnec, Justine Schaeffer, Caroline Picard, Laura Barrot, Stéphane Barron, Audrey Vallve, Aurélie Duthey, Frédéric Jacquot, Cathy Boehringer, Grégory Jouvion, Natalia Pietrosemoli, Rachel Legendre, Marie-Agnès Dillies, Richard Allan, Catherine Legras-Lachuer, Caroline Carbonnelle, Hervé Raoul, Sylvain Baize

Source: Communications Biology, Vol 4, Iss 1, Pp 1-19 (2021)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2399-3642

Access URL: https://doaj.org/article/97528d0810d148d594a62a4f23cbd59b

Temporal evolution of the humoral antibody response after Ebola virus disease in Guinea: a 60-month observational prospective cohort study

Authors: Mamadou Saliou Kalifa Diallo, MSc, Ahidjo Ayouba, PhD, Alpha Kabinet Keita, PhD, Guillaume Thaurignac, MSc, Mamadou Saliou Sow, MD, Cécé Kpamou, MSc, Thierno Alimou Barry, MD, Philippe Msellati, PhD, Jean-François Etard, PhD, Martine Peeters, PhD, René Ecochard, ProfPhD, Eric Delaporte, ProfPhD, Abdoulaye Toure, PhD, Ahidjo Ayouba, Sylvain Baize, Kaba Bangoura, Alimou Barry, Moumié Barry, Mamoudou Cissé, Mohammed Cissé, Eric Delaporte, Jean-François Delfraissy, Christelle Delmas, Alice Desclaux, Saliou Bella Diallo, Mamadou Safiatou Diallo, Mariama Sadjo Diallo, Jean-François Étard, Cécile Etienne, Ousmane Faye, Ibrahima Fofana, Bruno Granouillac, Suzanne Izard, Djenaba Kassé, Alpha Kabinet Keita, Sakoba Keita, Lamine Koivogui, Cécé Kpamou, Christine Lacarabaratz, Sandrine Leroy, Claire Levy Marchal, Yves Levy, N'Fally Magassouba, Laura March, Vincent Mendiboure, Philippe Msellati, Harissatou Niane, Martine Peeters, Yves-Marie Pers, Hervé Raoul, Sidi Lamine Sacko, Ibrahima Savané, Mamadou Saliou Sow, Bernard Taverne, Abdoulaye Touré, Fodé Amara Traoré, Falaye Traoré, Yamoussa Youla, Yazdan Yazdanpanah

Source: The Lancet Microbe, Vol 2, Iss 12, Pp e676-e684 (2021)

Subject Terms: Medicine (General), R5-920, Microbiology, QR1-502

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666524721001701; https://doaj.org/toc/2666-5247

Access URL: https://doaj.org/article/708b31ffbff24a4484bb0cc539035b8c

Modeling Favipiravir Antiviral Efficacy Against Emerging Viruses: From Animal Studies to Clinical Trials

Authors: Vincent Madelain, France Mentré, Sylvain Baize, Xavier Anglaret, Cédric Laouénan, Lisa Oestereich, Thi Huyen Tram Nguyen, Denis Malvy, Géraldine Piorkowski, Frederik Graw, Stephan Günther, Hervé Raoul, Xavier deLamballerie, Jérémie Guedj

Source: CPT: Pharmacometrics & Systems Pharmacology, Vol 9, Iss 5, Pp 258-271 (2020)

Subject Terms: Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://doaj.org/toc/2163-8306

Access URL: https://doaj.org/article/c3eb6c0c096749a2a43547dd624cdc4d

Rational design of universal immunotherapy for TfR1-tropic arenaviruses

Authors: Hadas Cohen-Dvashi, Ron Amon, Krystle N. Agans, Robert W. Cross, Aliza Borenstein-Katz, Mathieu Mateo, Sylvain Baize, Vered Padler-Karavani, Thomas W. Geisbert, Ron Diskin

Source: Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/751b79cf93674fd5a0d73e4333ca7172

Lassa fever in Benin: description of the 2014 and 2016 epidemics and genetic characterization of a new Lassa virus

Authors: Anges Yadouleton, Caroline Picard, Toni Rieger, Frederic Loko, Daniel Cadar, Emile Cossi Kouthon, Emmanuel Obolli Job, Honoré Bankolé, Lisa Oestereich, Fernand Gbaguidi, Meike Pahlman, Beate Becker-Ziaja, Alexandra Journeaux, Delphine Pannetier, Stéphane Mély, Stéphanie Mundweiler, Damien Thomas, Leon Kohossi, Raoul Saizonou, Clement Glele Kakaï, Magloire Da Silva, Sonia Kossoubedie, André Lukusa Kakonku, Pierre M’Pelé, Stephan Gunther, Sylvain Baize, Elisabeth Fichet-Calvet

Source: Emerging Microbes and Infections, Vol 9, Iss 1, Pp 1761-1770 (2020)

Subject Terms: Lassa fever, Lassa virus, genome, Benin, outbreak, phylogeny, Infectious and parasitic diseases, RC109-216, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2222-1751

Access URL: https://doaj.org/article/f566fe902bc347b8a381b96b85860e89

Fatal Case of Lassa Fever, Bangolo District, Côte d’Ivoire, 2015

Authors: Mathieu Mateo, Caroline Picard, Yahaya Sylla, Emilie Kamo, Danielle Odegue, Alexandra Journeaux, Stéphane Kouassi Kan, Marcelle Money, David N’Golo Coulibaly, Eugène Koffi, Souleymane Meite, Véronique Akran, Hervé Kadjo, Edgard Adjogoua, Solange N’Gazoa Kakou, Sylvain Baize, Mireille Dosso

Source: Emerging Infectious Diseases, Vol 25, Iss 9, Pp 1753-1756 (2019)

Subject Terms: Lassa fever, Lassa fever virus, viruses, retrospective identification, fatal case, zoonoses, Medicine, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: https://wwwnc.cdc.gov/eid/article/25/9/19-0239_article; https://doaj.org/toc/1080-6040; https://doaj.org/toc/1080-6059

Access URL: https://doaj.org/article/c2c55f3e60d248bbb95f8e333fc10e22

Early control of viral load by favipiravir promotes survival to Ebola virus challenge and prevents cytokine storm in non-human primates.

Authors: Stéphanie Reynard, Emilie Gloaguen, Nicolas Baillet, Vincent Madelain, Jérémie Guedj, Hervé Raoul, Xavier de Lamballerie, Jimmy Mullaert, Sylvain Baize

Source: PLoS Neglected Tropical Diseases, Vol 15, Iss 3, p e0009300 (2021)

Subject Terms: Arctic medicine. Tropical medicine, RC955-962, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0009300&type=printable; https://doaj.org/toc/1935-2727; https://doaj.org/toc/1935-2735

Access URL: https://doaj.org/article/83f0b0b6212d4887b5b86a6b168294a4

Ebola viral dynamics in nonhuman primates provides insights into virus immuno-pathogenesis and antiviral strategies

Authors: Vincent Madelain, Sylvain Baize, Frédéric Jacquot, Stéphanie Reynard, Alexandra Fizet, Stephane Barron, Caroline Solas, Bruno Lacarelle, Caroline Carbonnelle, France Mentré, Hervé Raoul, Xavier de Lamballerie, Jérémie Guedj

Source: Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/8007c9d9b043441c879ab95a1e9f13f9

Infection of Human Endothelial Cells with Lassa Virus Induces Early but Transient Activation and Low Type I IFN Response Compared to the Closely-Related Nonpathogenic Mopeia Virus

Authors: Othmann Merabet, Natalia Pietrosemoli, Emeline Perthame, Jean Armengaud, Jean-Charles Gaillard, Virginie Borges-Cardoso, Maïlys Daniau, Catherine Legras-Lachuer, Xavier Carnec, Sylvain Baize

Source: Viruses, Vol 14, Iss 3, p 652 (2022)

Subject Terms: Lassa virus, endothelial cells, viral hemorrhagic fevers, Mopeia virus, pathogenicity, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4915/14/3/652; https://doaj.org/toc/1999-4915

Access URL: https://doaj.org/article/9230cc31eef24b1d9b66c53526d47979

Lassa virus activates myeloid dendritic cells but suppresses their ability to stimulate T cells.

Authors: Justine Schaeffer, Xavier Carnec, Stéphanie Reynard, Mathieu Mateo, Caroline Picard, Natalia Pietrosemoli, Marie-Agnès Dillies, Sylvain Baize

Source: PLoS Pathogens, Vol 14, Iss 11, p e1007430 (2018)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC6258464?pdf=render; https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

Access URL: https://doaj.org/article/b4064dfc3c44436fac97cee19e6c228a

Interference with the production of infectious viral particles and bimodal inhibition of replication are broadly conserved antiviral properties of IFITMs.

Authors: Kevin Tartour, Xuan-Nhi Nguyen, Romain Appourchaux, Sonia Assil, Véronique Barateau, Louis-Marie Bloyet, Julien Burlaud Gaillard, Marie-Pierre Confort, Beatriz Escudero-Perez, Henri Gruffat, Saw See Hong, Marie Moroso, Olivier Reynard, Stéphanie Reynard, Elodie Decembre, Najate Ftaich, Axel Rossi, Nannan Wu, Frédérick Arnaud, Sylvain Baize, Marlène Dreux, Denis Gerlier, Glaucia Paranhos-Baccala, Viktor Volchkov, Philippe Roingeard, Andrea Cimarelli

Source: PLoS Pathogens, Vol 13, Iss 9, p e1006610 (2017)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

Access URL: https://doaj.org/article/a1ae7ec7be9d4b84a06a17adedcfc46d

Nomenclature- and Database-Compatible Names for the Two Ebola Virus Variants that Emerged in Guinea and the Democratic Republic of the Congo in 2014

Authors: Jens H. Kuhn, Kristian G. Andersen, Sylvain Baize, Yīmíng Bào, Sina Bavari, Nicolas Berthet, Olga Blinkova, J. Rodney Brister, Anna N. Clawson, Joseph Fair, Martin Gabriel, Robert F. Garry, Stephen K. Gire, Augustine Goba, Jean-Paul Gonzalez, Stephan Günther, Christian T. Happi, Peter B. Jahrling, Jimmy Kapetshi, Gary Kobinger, Jeffrey R. Kugelman, Eric M. Leroy, Gael Darren Maganga, Placide K. Mbala, Lina M. Moses, Jean-Jacques Muyembe-Tamfum, Magassouba N'Faly, Stuart T. Nichol, Sunday A. Omilabu, Gustavo Palacios, Daniel J. Park, Janusz T. Paweska, Sheli R. Radoshitzky, Cynthia A. Rossi, Pardis C. Sabeti, John S. Schieffelin, Randal J. Schoepp, Rachel Sealfon, Robert Swanepoel, Jonathan S. Towner, Jiro Wada, Nadia Wauquier, Nathan L. Yozwiak, Pierre Formenty

Source: Viruses, Vol 6, Iss 11, Pp 4760-4799 (2014)

Subject Terms: Ebola, Ebola virus, ebolavirus, filovirid, Filoviridae, filovirus, genome annotation, Lomela, Lokolia, Makona, mononegavirad, Mononegavirales, mononegavirus, virus classification, virus isolate, virus nomenclature, virus strain, virus taxonomy, virus variant, Microbiology, QR1-502

File Description: electronic resource

Relation: http://www.mdpi.com/1999-4915/6/11/4760; https://doaj.org/toc/1999-4915

Access URL: https://doaj.org/article/7f8b803671844b9a89919675c08d6a39

E3 Ligase ITCH Interacts with the Z Matrix Protein of Lassa and Mopeia Viruses and Is Required for the Release of Infectious Particles

Authors: Nicolas Baillet, Sophie Krieger, Xavier Carnec, Mathieu Mateo, Alexandra Journeaux, Othmann Merabet, Valérie Caro, Frédéric Tangy, Pierre-Olivier Vidalain, Sylvain Baize

Source: Viruses, Vol 12, Iss 1, p 49 (2019)

Subject Terms: lassa fever, lasv, mopv, itch, z matrix protein, yeast two-hybrid screening, egress, infection, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4915/12/1/49; https://doaj.org/toc/1999-4915

Access URL: https://doaj.org/article/a6ea2978badb41048f265ec80dd35e80

Favipiravir pharmacokinetics in Ebola-Infected patients of the JIKI trial reveals concentrations lower than targeted.

Authors: Thi Huyen Tram Nguyen, Jérémie Guedj, Xavier Anglaret, Cédric Laouénan, Vincent Madelain, Anne-Marie Taburet, Sylvain Baize, Daouda Sissoko, Boris Pastorino, Anne Rodallec, Géraldine Piorkowski, Sara Carazo, Mamoudou N Conde, Jean-Luc Gala, Joseph Akoi Bore, Caroline Carbonnelle, Frédéric Jacquot, Hervé Raoul, Denis Malvy, Xavier de Lamballerie, France Mentré, JIKI study group

Source: PLoS Neglected Tropical Diseases, Vol 11, Iss 2, p e0005389 (2017)

Subject Terms: Arctic medicine. Tropical medicine, RC955-962, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5340401?pdf=render; https://doaj.org/toc/1935-2727; https://doaj.org/toc/1935-2735

Access URL: https://doaj.org/article/7f6efdf3b05345baa7f586719e1ce176

Immune Responses and Lassa Virus Infection

Authors: Sylvain Baize, Marion Russier, Delphine Pannetier

Source: Viruses, Vol 4, Iss 11, Pp 2766-2785 (2012)

Subject Terms: Lassa virus, hemorrhagic fever, T-cell responses, antigen-presenting cells, immunity, Microbiology, QR1-502

File Description: electronic resource

Relation: http://www.mdpi.com/1999-4915/4/11/2766; https://doaj.org/toc/1999-4915

Access URL: https://doaj.org/article/a8c13308f64043499583cb6e057c1f4e