ASO targeting RBM3 temperature‐controlled poison exon splicing prevents neurodegeneration in vivo

Authors: Preußner, Marco, Smith, Heather L, Hughes, Daniel, Zhang, Min, Emmerichs, Ann‐Kathrin, Scalzitti, Silvia, Peretti, Diego, Swinden, Dean, Neumann, Alexander, Haltenhof, Tom, Mallucci, Giovanna R, Heyd, Florian

Source: EMBO molecular medicine. 15(5)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100185476479.0x000001&indx=1&recIds=ETOCvdc_100185476479.0x000001

Astrocyte Unfolded Protein Response Induces a Specific Reactivity State that Causes Non-Cell-Autonomous Neuronal Degeneration

Authors: Smith, Heather L., Freeman, Oliver J., Butcher, Adrian J., Holmqvist, Staffan, Humoud, Ibrahim, Schätzl, Tobias, Hughes, Daniel T., Verity, Nicholas C., Swinden, Dean P., Hayes, Joseph, de Weerd, Lis, Rowitch, David H., Franklin, Robin J.M., Mallucci, Giovanna R.

Source: In Neuron 4 March 2020 105(5):855-866

Trazodone rescues dysregulated synaptic and mitochondrial nascent proteomes in prion neurodegeneration.

Authors: Albert-Gasco, Hector^1,2, Smith, Heather L^1,2, Alvarez-Castelao, Beatriz^3,4, Swinden, Dean^1,2, Halliday, Mark², Janaki-Raman, Sudha⁵, Butcher, Adrian J^1,2, Mallucci, Giovanna R^1,2, gmallucci@altoslabs.com

Source: Brain: A Journal of Neurology; Feb2024, Vol. 147 Issue 2, p649-664, 16p

TrkB signaling regulates the cold-shock protein RBM3-mediated neuroprotection.

Authors: Peretti, Diego, Smith, Heather L., Verity, Nicholas, Humoud, Ibrahim, Weerd, Lis de, Swinden, Dean P., Hayes, Joseph, Mallucci, Giovanna R.

Source: Life Science Alliance; Apr2021, Vol. 4 Issue 4, p1-16, 16p