xCT as a potential marker for neuroendocrine cells in high-risk prostate cancer and the relation to AL122023.1-miR-26a/30d/30e axis.

Authors: Elena D Wilhelm, Jaroslaw T Dankert, Marc Wiesehöfer, Sven Wach, Mathias Wagner, Martin Spahn, Marianna Kruithof-de Julio, Gunther Wennemuth

Source: PLoS ONE, Vol 20, Iss 1, p e0318213 (2025)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/a45f0995db4b45438e35899547e4c22c

HLA-G expression associates with immune evasion muscle-invasive urothelial cancer and drives prognostic relevance

Authors: Annalena Branz, Christian Matek, Fabienne Lange, Veronika Bahlinger, Niklas Klümper, Michael Hölzel, Pamela L. Strissel, Reiner Strick, Danijel Sikic, Sven Wach, Helge Taubert, Bernd Wullich, Arndt Hartmann, Barbara Seliger, Markus Eckstein

Source: Frontiers in Immunology, Vol 15 (2024)

Subject Terms: HLA-G, urothelial cancer, immune checkpoints, immune evasion, immune microenvironment, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1478196/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/9a3359d7262e4505b637932af7440aae

NanoLuc Binary Technology as a methodological approach: an important new tool for studying the localization of androgen receptor and androgen receptor splice variant V7 homo and heterodimers

Authors: Juan Guzman, Katrin Weigelt, Angela Neumann, Philipp Tripal, Benjamin Schmid, Zoltán Winter, Ralph Palmisano, Zoran Culig, Marcus V. Cronauer, Paul Muschler, Bernd Wullich, Helge Taubert, Sven Wach

Source: BMC Cancer, Vol 24, Iss 1, Pp 1-13 (2024)

Subject Terms: Androgen receptor, Androgen receptor variant 7, Prostate cancer, NanoLuc Binary Technology, Homodimer, Heterodimer, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2407

Access URL: https://doaj.org/article/540315149f484863b24ccb2561a69445

A deep‐learning workflow to predict upper tract urothelial carcinoma protein‐based subtypes from H&E slides supporting the prioritization of patients for molecular testing

Authors: Miriam Angeloni, Thomas vanDoeveren, Sebastian Lindner, Patrick Volland, Jorina Schmelmer, Sebastian Foersch, Christian Matek, Robert Stoehr, Carol I Geppert, Hendrik Heers, Sven Wach, Helge Taubert, Danijel Sikic, Bernd Wullich, Geert JLH vanLeenders, Vasily Zaburdaev, Markus Eckstein, Arndt Hartmann, Joost L Boormans, Fulvia Ferrazzi, Veronika Bahlinger

Source: The Journal of Pathology: Clinical Research, Vol 10, Iss 2, Pp n/a-n/a (2024)

Subject Terms: deep‐learning, digital pathology, immunohistochemistry, protein‐based subtypes, targeted therapy, upper tract urothelial carcinoma, Pathology, RB1-214

File Description: electronic resource

Relation: https://doaj.org/toc/2056-4538

Access URL: https://doaj.org/article/ea49233d91ae4f1c9eec6b27ab16c36c

Stromal-epithelial interaction induces GALNT14 in prostate carcinoma cells

Authors: Elena D. Czyrnik, Marc Wiesehöfer, Jaroslaw T. Dankert, Sven Wach, Mathias Wagner, Martin Spahn, Marianna Kruithof de Julio, Gunther Wennemuth

Source: Frontiers in Oncology, Vol 13 (2023)

Subject Terms: prostate tissue, prostate carcinoma, stromal-epithelial interaction, paracrine interaction, co-culture, GALNT14, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2023.1212585/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/2e9955f506ff4e5da1eeed68d036f8f2

Characterization of the expression and immunological impact of the transcriptional activator CREB in renal cell carcinoma

Authors: Michael Friedrich, Christine Stoehr, Simon Jasinski-Bergner, Arndt Hartmann, Sven Wach, Bernd Wullich, André Steven, Barbara Seliger

Source: Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-11 (2020)

Subject Terms: CREB, HLA-G, Renal cell carcinoma, Immune cell infiltration, Medicine

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12967-020-02544-0; https://doaj.org/toc/1479-5876

Access URL: https://doaj.org/article/7db6c0a4e8964cb5bbad5f10158ab1b6

The Human Leukocyte Antigen G as an Immune Escape Mechanism and Novel Therapeutic Target in Urological Tumors

Authors: Simon Jasinski-Bergner, Markus Eckstein, Helge Taubert, Sven Wach, Christian Fiebig, Reiner Strick, Arndt Hartmann, Barbara Seliger

Source: Frontiers in Immunology, Vol 13 (2022)

Subject Terms: HLA-G, renal cell carcinoma, epithelial bladder cancer, immune evasion, immunotherapy, immune cell infiltration, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.811200/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/b14a204c9ae445e68cca1ef25bf20735

Exploring the MIR143-UPAR Axis for the Inhibition of Human Prostate Cancer Cells In Vitro and In Vivo

Authors: Sven Wach, Madeleine Brandl, Hannes Borchardt, Katrin Weigelt, Sabine Lukat, Elke Nolte, Omar Al-Janabi, Martin Hart, Friedrich Grässer, Johannes Giedl, Rudolf Jung, Robert Stöhr, Arndt Hartmann, Verena Lieb, Sabrina Höbel, Anna Peters, Claudia Stäubert, Bernd Wullich, Helge Taubert, Achim Aigner

Source: Molecular Therapy: Nucleic Acids, Vol 16, Iss , Pp 272-283 (2019)

Subject Terms: Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2162253119300514; https://doaj.org/toc/2162-2531

Access URL: https://doaj.org/article/d8d765c582e04b049197e5a16a0b421e

Androgen Receptor mRNA Expression in Urothelial Carcinoma of the Bladder: A Retrospective Analysis of Two Independent Cohorts

Authors: Danijel Sikic, Ralph M. Wirtz, Sven Wach, Lars Dyrskjøt, Philipp Erben, Christian Bolenz, Johannes Breyer, Wolfgang Otto, Katherine A. Hoadley, Seth P. Lerner, Markus Eckstein, Arndt Hartmann, Bastian Keck

Source: Translational Oncology, Vol 12, Iss 4, Pp 661-668 (2019)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1936523318306478; https://doaj.org/toc/1936-5233

Access URL: https://doaj.org/article/07ed23158aca44659eca38a9a94652e4

Cell-Free DNA Sequencing Reveals Gene Variants in DNA Damage Repair Genes Associated with Prognosis of Prostate Cancer Patients

Authors: Verena Lieb, Amer Abdulrahman, Katrin Weigelt, Siegfried Hauch, Michael Gombert, Juan Guzman, Laura Bellut, Peter J. Goebell, Robert Stöhr, Arndt Hartmann, Bernd Wullich, Helge Taubert, Sven Wach

Source: Cells, Vol 11, Iss 22, p 3618 (2022)

Subject Terms: prostate cancer, cfDNA, sequence variants, DDR genes, ATM, NBN, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/11/22/3618; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/d3c19022b16c462592f34db814de2119

Endogenous Retroviral–K Envelope Is a Novel Tumor Antigen and Prognostic Indicator of Renal Cell Carcinoma

Authors: Veronika Weyerer, Pamela L. Strissel, Christine Stöhr, Markus Eckstein, Sven Wach, Helge Taubert, Lisa Brandl, Carol I. Geppert, Bernd Wullich, Holger Cynis, Matthias W. Beckmann, Barbara Seliger, Arndt Hartmann, Reiner Strick

Source: Frontiers in Oncology, Vol 11 (2021)

Subject Terms: endogenous retrovirus, ERV-K, renal cell carcinoma, tumor antigen, patient prognosis, p53, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2021.657187/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/be0eec9e1ca64ea59c35a6196ec554a4

Cytotoxic T-cell-related gene expression signature predicts improved survival in muscle-invasive urothelial bladder cancer patients after radical cystectomy and adjuvant chemotherapy

Authors: Arndt Hartmann, Bernd Wullich, Markus Eckstein, Pamela Strissel, Reiner Strick, Veronika Weyerer, Ralph Wirtz, Carolin Pfannstiel, Adrian Wullweber, Fabienne Lange, Philipp Erben, Robert Stoehr, Simone Bertz, Carol Imanuel Geppert, Nicole Fuhrich, Helge Taubert, Sven Wach, Johannes Breyer, Wolfgang Otto, Maximilian Burger, Christian Bolenz, Bastian Keck, Danijel Sikic

Source: Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://jitc.bmj.com/content/8/1/e000162.full; https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/8c572575ad5b414ebe80d9b210269148

Combined miR-486 and GP88 (Progranulin) Serum Levels Are Suggested as Supportive Biomarkers for Therapy Decision in Elderly Prostate Cancer Patients

Authors: Alexander Fichte, Angela Neumann, Katrin Weigelt, Juan Guzman, Thilo Jansen, Julia Keinert, Ginette Serrero, Binbin Yue, Robert Stöhr, Thomas Greither, Arndt Hartmann, Bernd Wullich, Helge Taubert, Sven Wach, Verena Lieb

Source: Life, Vol 12, Iss 5, p 732 (2022)

Subject Terms: progranulin, miRNAs, prostate cancer, serum level, predictive biomarker, age, Science

File Description: electronic resource

Relation: https://www.mdpi.com/2075-1729/12/5/732; https://doaj.org/toc/2075-1729

Access URL: https://doaj.org/article/0c58d81185b4407e855e052eb59ab2cf

Reduced Recurrence Rates Are Associated with Photodynamic Diagnostics Compared to White Light after Extended Transurethral Resection of Bladder Tumors

Authors: Alexander Marquardt, Mario Richterstetter, Helge Taubert, Arndt Hartmann, Bernd Wullich, Verena Lieb, Laura Bellut, Sven Wach, Hendrik Apel

Source: Life, Vol 12, Iss 5, p 641 (2022)

Subject Terms: transurethral resection, photodynamic diagnostics, recurrence-free survival, Science

File Description: electronic resource

Relation: https://www.mdpi.com/2075-1729/12/5/641; https://doaj.org/toc/2075-1729

Access URL: https://doaj.org/article/a820aa9214694bccb0a4f61d8ad7b349

Cell-Free DNA Variant Sequencing Using Plasma and AR-V7 Testing of Circulating Tumor Cells in Prostate Cancer Patients

Authors: Verena Lieb, Amer Abdulrahman, Katrin Weigelt, Siegfried Hauch, Michael Gombert, Juan Guzman, Laura Bellut, Peter J. Goebell, Robert Stöhr, Arndt Hartmann, Bernd Wullich, Helge Taubert, Sven Wach

Source: Cells, Vol 10, Iss 11, p 3223 (2021)

Subject Terms: prostate cancer, cfDNA, CTCs, prognosis, sequence variants, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/10/11/3223; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/0a3f909d9f53434e8e23bd99bd2a73cd

High Androgen Receptor mRNA Expression Is Independently Associated with Prolonged Cancer-Specific and Recurrence-Free Survival in Stage T1 Bladder Cancer

Authors: Danijel Sikic, Johannes Breyer, Arndt Hartmann, Maximilian Burger, Philipp Erben, Stefan Denzinger, Markus Eckstein, Robert Stöhr, Sven Wach, Bernd Wullich, Bastian Keck, Ralph M. Wirtz, Wolfgang Otto

Source: Translational Oncology, Vol 10, Iss 3, Pp 340-345 (2017)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1936523316302790; https://doaj.org/toc/1936-5233

Access URL: https://doaj.org/article/9e821f7594bb4f59a74c24d26f0ae2e6

Combination of GP88 Expression in Tumor Cells and Tumor-Infiltrating Immune Cells Is an Independent Prognostic Factor for Bladder Cancer Patients

Authors: Markus Eckstein, Verena Lieb, Rudolf Jung, Danijel Sikic, Katrin Weigelt, Robert Stöhr, Carol Geppert, Veronika Weyerer, Simone Bertz, Ginette Serrero, Binbin Yue, Arndt Hartmann, Bernd Wullich, Helge Taubert, Sven Wach

Source: Cells, Vol 10, Iss 7, p 1796 (2021)

Subject Terms: GP88, bladder cancer, prognosis, tumor cells, immune cells, lymph node stage, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/10/7/1796; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/58e242a098ee456492625b9878ffe193

High Androgen Receptor mRNA Expression Is Associated with Improved Outcome in Patients with High-Risk Non-Muscle-Invasive Bladder Cancer

Authors: Danijel Sikic, Helge Taubert, Ralph M. Wirtz, Johannes Breyer, Markus Eckstein, Veronika Weyerer, Jennifer Kubon, Philipp Erben, Christian Bolenz, Maximilian Burger, Arndt Hartmann, Bernd Wullich, Sven Wach, Bastian Keck

Source: Life, Vol 11, Iss 7, p 642 (2021)

Subject Terms: androgen receptor, bladder cancer, KRT5, KRT20, mRNA, NMIBC, Science

File Description: electronic resource

Relation: https://www.mdpi.com/2075-1729/11/7/642; https://doaj.org/toc/2075-1729

Access URL: https://doaj.org/article/201545d6fae9422d80d7391325d097d2

Serum miRNAs Support the Indication for MRI-Ultrasound Fusion-Guided Biopsy of the Prostate in Patients with Low-PI-RADS Lesions

Authors: Bastian Keck, Angelika Borkowetz, Julia Poellmann, Thilo Jansen, Moritz Fischer, Susanne Fuessel, Andreas Kahlmeyer, Manfred Wirth, Johannes Huber, Alexander Cavallaro, Matthias Hammon, Ivan Platzek, Arndt Hartmann, Gustavo Baretton, Frank Kunath, Danijel Sikic, Helge Taubert, Bernd Wullich, Kati Erdmann, Sven Wach

Source: Cells, Vol 10, Iss 6, p 1315 (2021)

Subject Terms: diagnosis, microRNA, miRNA, mpMRI, PI-RADS, prostate biopsy, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/10/6/1315; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/a71bd8aa6f6e4272b3d8ca217a30143f

Genetic variation at the 8q24.21 renal cancer susceptibility locus affects HIF binding to a MYC enhancer

Authors: Steffen Grampp, James L. Platt, Victoria Lauer, Rafik Salama, Franziska Kranz, Viviana K. Neumann, Sven Wach, Christine Stöhr, Arndt Hartmann, Kai-Uwe Eckardt, Peter J. Ratcliffe, David R. Mole, Johannes Schödel

Source: Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/fe92f998e7f14012877889b0b60dd9cb