Epigenetic and senescence markers indicate an accelerated ageing-like state in women with preeclamptic pregnancies

Authors: Suvakov, Sonja, Ghamrawi, Ranine, Cubro, Hajrunisa, Tu, Haitao, White, Wendy M., Tobah, Yvonne S. Butler, Milic, Natasa M., Grande, Joseph P., Cunningham, Julie M., Chebib, Fouad T., Prata, Larissa G.P. Langhi, Zhu, Yi, Tchkonia, Tamara, Kirkland, James L., Nath, Karl A., Milosavljevic, Aleksandar, Garovic, Vesna D.

Source: In EBioMedicine August 2021 70

Mechanisms of vascular dysfunction in the interleukin-10–deficient murine model of preeclampsia indicate nitric oxide dysregulation

Authors: Cubro, Hajrunisa, Nath, Karl A., Suvakov, Sonja, Garcia-Valencia, Oscar, Parashuram, Santosh, White, Wendy M., Weissgerber, Tracey L., Nath, Meryl C., Milic, Natasa M., Sontag, Fernando, d’Uscio, Livius V., Zhu, Yi, Kirkland, James L., Tchkonia, Tamar, Alexander, Mariam P., Quinton, Reade A., Katusic, Zvonimir S., Grande, Joseph P., Garovic, Vesna D.

Source: In Kidney International March 2021 99(3):646-656

COVID-19 and Sex Differences: Mechanisms and Biomarkers

Authors: Haitao, Tu, Vermunt, Jane V., Abeykoon, Jithma, Ghamrawi, Ranine, Gunaratne, Madugodaralalage, Jayachandran, Muthuvel, Narang, Kavita, Parashuram, Santosh, Suvakov, Sonja, Garovic, Vesna D.

Source: In Mayo Clinic Proceedings October 2020 95(10):2189-2203

Overlapping pathogenic signalling pathways and biomarkers in preeclampsia and cardiovascular disease

Authors: Suvakov, Sonja, Bonner, Emma, Nikolic, Valentina, Jerotic, Djurdja, Simic, Tatjana P, Garovic, Vesna D, Lopez-Campos, Guillermo, McClements, Lana

Source: In Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health April 2020 20:131-136

Chronic prostatitis/chronic pelvic pain syndrome increases susceptibility to seizures in rats and alters brain levels of IL-1β and IL-6

Authors: Šutulović, Nikola, Grubač, Željko, Šuvakov, Sonja, Jovanović, Đurđa, Puškaš, Nela, Macut, Đuro, Marković, Aleksandra Rašić, Simić, Tatjana, Stanojlović, Olivera, Hrnčić, Dragan

Source: In Epilepsy Research July 2019 153:19-27

GSTM1 genotype is an independent prognostic factor in clear cell renal cell carcinoma

Authors: Coric, Vesna M., Simic, Tatjana P., Pekmezovic, Tatjana D., Basta-Jovanovic, Gordana M., Savic-Radojevic, Ana R., Radojevic-Skodric, Sanja M., Matic, Marija G., Suvakov, Sonja R., Dragicevic, Dejan P., Radic, Tanja M., Dzamic, Zoran M., Pljesa-Ercegovac, Marija S.

Source: In Urologic Oncology: Seminars and Original Investigations June 2017 35(6):409-417

Soluble urinary somatic angiotensin converting enzyme is overexpressed in patients with preeclampsia: a potential new marker for the disease?

Authors: Sontag, Fernando^1,2,3 (AUTHOR), Suvakov, Sonja¹ (AUTHOR), Garovic, Vesna D¹ (AUTHOR) garovic.vesna@mayo.edu

Source: Hypertension in Pregnancy. Aug-Nov2022, Vol. 41 Issue 3/4, p190-197. 8p.

Subject Terms: *ANGIOTENSIN converting enzyme, *URINALYSIS, *PREECLAMPSIA, *DIASTOLIC blood pressure, *RENIN-angiotensin system, *PITUITARY dwarfism

Women With a History of Preeclampsia Exhibit Accelerated Aging and Unfavorable Profiles of Senescence Markers.

Authors: Suvakov, Sonja, Vaughan, Lisa E., Parashuram, Santosh, Butler Tobah, Yvonne S., Jayachandran, Muthuvel, Kattah, Andrea, Chamberlain, Alanna M., Bielinski, Suzette J., Milic, Natasa, Garovic, Vesna D.

Source: Hypertension (0194911X); Jul2024, Vol. 81 Issue 7, p1550-1560, 11p

Association of glutathione-S-transferase gene polymorphism and lipoprotein subclasses in hemodialysis patients

Authors: Vekic, Jelena, Zeljkovic, Aleksandra, Jelic-Ivanovic, Zorana, Damjanovic, Tatjana, Suvakov, Sonja, Matic, Marija, Savic-Radojevic, Ana, Simic, Tatjana, Spasojevic-Kalimanovska, Vesna, Gojkovic, Tamara, Spasic, Slavica, Dimkovic, Nada

Source: In Clinical Biochemistry April 2014 47(6):398-403

Markers of Oxidative Damage and Antioxidant Enzyme Activities as Predictors of Morbidity and Mortality in Patients With Chronic Heart Failure

Authors: Radovanovic, Slavica, Savic-Radojevic, Ana, Pljesa-Ercegovac, Marija, Djukic, Tatjana, Suvakov, Sonja, Krotin, Mirjana, Simic, Dragan V., Matic, Marija, Radojicic, Zoran, Pekmezovic, Tatjana, Simic, Tatjana

Source: In Journal of Cardiac Failure June 2012 18(6):493-501

SenNet recommendations for detecting senescent cells in different tissues

Authors: Suryadevara, Vidyani, Hudgins, Adam D., Rajesh, Adarsh, Pappalardo, Alberto, Karpova, Alla, Dey, Amit K., Hertzel, Ann, Agudelo, Anthony, Rocha, Azucena, Soygur, Bikem, Schilling, Birgit, Carver, Chase M., Aguayo-Mazzucato, Cristina, Baker, Darren J., Bernlohr, David A., Jurk, Diana, Mangarova, Dilyana B., Quardokus, Ellen M., Enninga, Elizabeth Ann L., Schmidt, Elizabeth L., Chen, Feng, Duncan, Francesca E., Cambuli, Francesco, Kaur, Gagandeep, Kuchel, George A., Lee, Gung, Daldrup-Link, Heike E., Martini, Helene, Phatnani, Hemali, Al-Naggar, Iman M., Rahman, Irfan, Nie, Jia, Passos, João F., Silverstein, Jonathan C., Campisi, Judith, Wang, Julia, Iwasaki, Kanako, Barbosa, Karina, Metis, Kay, Nernekli, Kerem, Niedernhofer, Laura J., Ding, Li, Wang, Lichao, Adams, Lisa C., Ruiyang, Liu, Doolittle, Madison L., Teneche, Marcos G., Schafer, Marissa J., Xu, Ming, Hajipour, Mohammadjavad, Boroumand, Mozhgan, Basisty, Nathan, Sloan, Nicholas, Slavov, Nikolai, Kuksenko, Olena, Robson, Paul, Gomez, Paul T., Vasilikos, Periklis, Adams, Peter D., Carapeto, Priscila, Zhu, Quan, Ramasamy, Ramalakshmi, Perez-Lorenzo, Rolando, Fan, Rong, Dong, Runze, Montgomery, Ruth R., Shaikh, Sadiya, Vickovic, Sanja, Yin, Shanshan, Kang, Shoukai, Suvakov, Sonja, Khosla, Sundeep, Garovic, Vesna D., Menon, Vilas, Xu, Yanxin, Song, Yizhe, Suh, Yousin, Dou, Zhixun, Neretti, Nicola

Source: Nature Reviews Molecular Cell Biology; 20240101, Issue: Preprints p1-23, 23p

The influence of uremic serum and GSTM1 knockdown on redox homeostasis in HUVECs

Authors: Jerotic, Djurdja, Suvakov, Sonja, Alqudah, Abdelrahim, Savic-Radojevic, Ana, Pljesa-Ercegovac, Marija, Coric, Vesna, McClements, Lana, Simic, Tatjana, Matic, Marija

Source: In Free Radical Biology and Medicine December 2021 177 Supplement 1

Impact of Aging and Cellular Senescence in the Pathophysiology of Preeclampsia

Authors: Suvakov, Sonja, Kattah, Andrea G., Gojkovic, Tamara, Enninga, Elizabeth A.L., Pruett, Jacob, Jayachandran, Muthuvel, Sousa, Ciria, Santos, Janelle, Abou Hassan, Coline, Gonzales-Suarez, Maria, Garovic, Vesna D.

Source: Comprehensive Physiology; October 2023, Vol. 13 Issue: 4 p5077-5114, 38p

The Association of Polymorphisms in Genes Encoding Antioxidant Enzymes GPX1 (rs1050450), SOD2 (rs4880) and Transcriptional Factor Nrf2 (rs6721961) with the Risk and Development of Prostate Cancer.

Authors: Djokic, Milica, Radic, Tanja, Santric, Veljko, Dragicevic, Dejan, Suvakov, Sonja, Mihailovic, Smiljana, Stankovic, Vesna, Cekerevac, Milica, Simic, Tatjana, Nikitovic, Marina, Coric, Vesna

Source: Medicina (1010660X); Oct2022, Vol. 58 Issue 10, p1414-N.PAG, 11p

Subject Terms: NUCLEAR factor E2 related factor, GENETIC polymorphisms, TRANSCRIPTION factors, SUPEROXIDES, SINGLE nucleotide polymorphisms, PROSTATE cancer, ENZYMES

Preeclampsia and the Kidney: Pathophysiology and Clinical Implications

Authors: Dines, Virginia, Suvakov, Sonja, Kattah, Andrea, Vermunt, Jane, Narang, Kavita, Jayachandran, Muthuvel, Abou Hassan, Coline, Norby, Alexander M., Garovic, Vesna D.

Source: Comprehensive Physiology; January 2023, Vol. 13 Issue: 1 p4231-4267, 37p

Nanoparticle-Enabled Multiplexed Electrochemical Immunoassay for Detection of Surface Proteins on Extracellular Vesicles.

Authors: Lee, Seonhwa, Crulhas, Bruno P., Suvakov, Sonja, Verkhoturov, Stanislav V., Verkhoturov, Dmitriy S., Eller, Michael J., Malhi, Harmeet, Garovic, Vesna D., Schweikert, Emile A., Stybayeva, Gulnaz, Revzin, Alexander

Source: ACS Applied Materials & Interfaces; 11/10/2021, Vol. 13 Issue 44, p52321-52332, 12p

GSTM1 Modulates Expression of Endothelial Adhesion Molecules in Uremic Milieu.

Authors: Jerotic, Djurdja, Suvakov, Sonja, Matic, Marija, Alqudah, Abdelrahim, Grieve, David J., Pljesa-Ercegovac, Marija, Savic-Radojevic, Ana, Damjanovic, Tatjana, Dimkovic, Nada, McClements, Lana, Simic, Tatjana

Source: Oxidative Medicine & Cellular Longevity; 1/27/2021, p1-12, 12p

Role of A Novel Angiogenesis FKBPL-CD44 Pathway in Preeclampsia Risk Stratification and Mesenchymal Stem Cell Treatment.

Authors: Todd, Naomi, McNally, Ross, Alqudah, Abdelrahim, Jerotic, Djurdja, Suvakov, Sonja, Obradovic, Danilo, Hoch, Denise, Hombrebueno, Jose R, Campos, Guillermo Lopez, Watson, Chris J, Gojnic-Dugalic, Miroslava, Simic, Tatjana P, Krasnodembskaya, Anna, Desoye, Gernot, Eastwood, Kelly-Ann, Hunter, Alyson J, Holmes, Valerie A, McCance, David R, Young, Ian S, Grieve, David J

Source: Journal of Clinical Endocrinology & Metabolism; Jan2021, Vol. 106 Issue 1, p26-41, 16p

Subject Terms: MESENCHYMAL stem cells, STEM cell treatment, PREECLAMPSIA, NEOVASCULARIZATION, PREGNANCY complications, CELL physiology, STEM cell transplantation, PREECLAMPSIA diagnosis, RESEARCH, CELL culture, RESEARCH methodology, CELL receptors, CASE-control method, PROGNOSIS, MEDICAL cooperation, EVALUATION research, RISK assessment, CELLULAR signal transduction, COMPARATIVE studies, PATHOLOGIC neovascularization, DRUG therapy, RESEARCH funding, EPITHELIAL cells

Cellular Senescence as an Underlying Mechanism of Kidney Injury in a Mouse Model of Preeclampsia

Authors: Suvakov, Sonja, Li, Xiaoyan, Hatamova, Jennet, Dokic, Vladimir, Gavrilovici, Paul, Li, Xiaogang, Garovic, Vesna D.

Source: Journal of the American Society of Nephrology; October 2024, Vol. 35 Issue: 10, Number 10 Supplement 10

Endothelial Glycocalyx Changes in Pregnancy: Relationship with Kidney Injury in Preeclampsia

Authors: Garcia Valencia, Oscar Alejandro, Suvakov, Sonja, Milic, Natasa, Dilmaghani, Darah, Dokic, Vladimir, Gavrilovici, Paul, Hatamova, Jennet, Miao, Jing, Garovic, Vesna D.

Source: Journal of the American Society of Nephrology; October 2024, Vol. 35 Issue: 10, Number 10 Supplement 10