The E6AP binding pocket of the HPV16 E6 oncoprotein provides a docking site for a small inhibitory peptide unrelated to E6AP, indicating druggability of E6.

Authors: Katia Zanier, Christina Stutz, Susanne Kintscher, Eileen Reinz, Peter Sehr, Julia Bulkescher, Karin Hoppe-Seyler, Gilles Travé, Felix Hoppe-Seyler

Source: PLoS ONE, Vol 9, Iss 11, p e112514 (2014)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4226571?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/1b12ea0faeee431489608df7d9fe21f4