Single-Cell Profiling Reveals Immune-Based Mechanisms Underlying Tumor Radiosensitization by a Novel Mn Porphyrin Clinical Candidate, MnTnBuOE-2-PyP5+ (BMX-001)

Authors: Sun Up Noh, Jinyeong Lim, Sung-Won Shin, Yeeun Kim, Woong-Yang Park, Ines Batinic-Haberle, Changhoon Choi, Won Park

Source: Antioxidants, Vol 13, Iss 4, p 477 (2024)

Subject Terms: Mn porphyrin clinical candidate, MnTnBuOE-2-PyP5+ (BMX-001, MnBuOE), single-cell RNA sequencing, tumor heterogeneity, tumor microenvironment, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.mdpi.com/2076-3921/13/4/477; https://doaj.org/toc/2076-3921

Access URL: https://doaj.org/article/313101eaefc24be3a8dd5c5e871dac6f

Targeting Na-H exchanger 1 overcomes nuclear factor kappa B-mediated tumor resistance to radiotherapy

Authors: Arang Son, Seoyeong Kang, Suha Choi, Sung-Won Shin, Yeeun Kim, Wankyu Kim, Changhoon Choi

Source: Neoplasia: An International Journal for Oncology Research, Vol 35, Iss , Pp 100862- (2023)

Subject Terms: Radiation therapy, Acquired radioresistance, Na-H exchanger 1, NF-κB, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1476558622000872; https://doaj.org/toc/1476-5586

Access URL: https://doaj.org/article/417343b4bec84bda8ffa875369fd7d4a

Anti-Tumor Effects of Wee1 Kinase Inhibitor with Radiotherapy in Human Cervical Cancer

Authors: Yoo-Young Lee, Young-Jae Cho, Sung-won Shin, Changhoon Choi, Ji-Yoon Ryu, Hye-Kyung Jeon, Jung-Joo Choi, Jae Ryoung Hwang, Chel Hun Choi, Tae-Joong Kim, Byoung- Gie Kim, Duk-Soo Bae, Won Park, Jeong-Won Lee

Source: Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/37fc5faa39024327940cb72635355416

MnTnHex-2-PyP5+, Coupled to Radiation, Suppresses Metastasis of 4T1 and MDA-MB-231 Breast Cancer via AKT/Snail/EMT Pathways

Authors: Sung-Won Shin, Changhoon Choi, Hakyoung Kim, Yeeun Kim, Sohee Park, Shin-Yeong Kim, Ines Batinic-Haberle, Won Park

Source: Antioxidants, Vol 10, Iss 11, p 1769 (2021)

Subject Terms: manganese porphyrin, MnTnHex-2-PyP5+, SOD mimics, radiation therapy, metastasis, NRF2, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.mdpi.com/2076-3921/10/11/1769; https://doaj.org/toc/2076-3921

Access URL: https://doaj.org/article/5b507cbe7fe8409d8046bef1324cff8d

Valproic Acid Sensitizes Hepatocellular Carcinoma Cells to Proton Therapy by Suppressing NRF2 Activation

Authors: Jeong Il Yu, Changhoon Choi, Sung-Won Shin, Arang Son, Ga-Haeng Lee, Shin-Yeong Kim, Hee Chul Park

Source: Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/4cec5c5dba794db6be2620d3f5dbff9f

Antigen-Capturing Mesoporous Silica Nanoparticles Enhance the Radiation-Induced Abscopal Effect in Murine Hepatocellular Carcinoma Hepa1-6 Models

Authors: Kyungmi Yang, Changhoon Choi, Hayeong Cho, Won-Gyun Ahn, Shin-Yeong Kim, Sung-Won Shin, Yeeun Kim, Taekyu Jang, Nohyun Lee, Hee Chul Park

Source: Pharmaceutics, Vol 13, Iss 11, p 1811 (2021)

Subject Terms: mesoporous silica nanoparticles, radiotherapy, immunotherapy, tumor microenvironment, abscopal effect, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4923/13/11/1811; https://doaj.org/toc/1999-4923

Access URL: https://doaj.org/article/ad7a455232484d50ab02c2fd50826ad4

Therapeutic Potential of (−)-Agelamide D, a Diterpene Alkaloid from the Marine Sponge Agelas sp., as a Natural Radiosensitizer in Hepatocellular Carcinoma Models

Authors: Changhoon Choi, Yeonwoo Cho, Arang Son, Sung-Won Shin, Yeon-Ju Lee, Hee Chul Park

Source: Marine Drugs, Vol 18, Iss 10, p 500 (2020)

Subject Terms: (−)-agelamide D, radiation therapy, hepatocellular carcinoma, unfolded protein response (UPR), activating transcription factor 4 (ATF4), Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/1660-3397/18/10/500; https://doaj.org/toc/1660-3397

Access URL: https://doaj.org/article/24594c3aba17428689a6f339493871ac

Targeting DNA-dependent protein kinase sensitizes hepatocellular carcinoma cells to proton beam irradiation through apoptosis induction.

Authors: Changhoon Choi, Arang Son, Ga-Haeng Lee, Sung-Won Shin, Sohee Park, Sang Hee Ahn, Yoonsun Chung, Jeong Il Yu, Hee Chul Park

Source: PLoS ONE, Vol 14, Iss 6, p e0218049 (2019)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/c645d8303edc4e66a2c54dbac562295c

Fucoidan-Manganese Dioxide Nanoparticles Potentiate Radiation Therapy by Co-Targeting Tumor Hypoxia and Angiogenesis

Authors: Sung-Won Shin, Wooju Jung, Changhoon Choi, Shin-Yeong Kim, Arang Son, Hakyoung Kim, Nohyun Lee, Hee Chul Park

Source: Marine Drugs, Vol 16, Iss 12, p 510 (2018)

Subject Terms: tumor hypoxia, radiation therapy, nanoparticles, fucoidan, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/1660-3397/16/12/510; https://doaj.org/toc/1660-3397

Access URL: https://doaj.org/article/58ec5814e8ef42a9ad2920c818a2e7b8

Publisher Correction: Valproic Acid Sensitizes Hepatocellular Carcinoma Cells to Proton Therapy by Suppressing NRF2 Activation

Authors: Jeong Il Yu, Changhoon Choi, Sung-Won Shin, Arang Son, Ga-Haeng Lee, Shin-Yeong Kim, Hee Chul Park

Source: Scientific Reports, Vol 8, Iss 1, Pp 1-1 (2018)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/5d0552c470064bc8bf0cd950391ff1b0

Ceramide as a Target of Marine Triterpene Glycosides for Treatment of Human Myeloid Leukemia

Authors: Seong-Hoon Yun, Sung-Won Shin, Valentin A. Stonik, Joo-In Park

Source: Marine Drugs, Vol 14, Iss 11, p 205 (2016)

Subject Terms: stichoposides, anti-leukemic activity, ceramide, sphingomyelinase, ceramide synthase, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.mdpi.com/1660-3397/14/11/205; https://doaj.org/toc/1660-3397

Access URL: https://doaj.org/article/aadbed2dc82c4c0e99949fdd8fe3cc43

A Low Power 128Mb Pseudo SRAM Using Hyper Destructive Read Architecture

Authors: Jin-Hong Ahn, Sang Hoon Hong, Jae-Bum Ko, Se Jun Kim, Sung-Won Shin, Hee-Bok Kang, Jae-Jin Lee, Joong-Sik Kih

Source: 2005 IEEE Asian Solid-State Circuits Conference Asian Solid-State Circuits Conference, 2005. :113-116 Nov, 2005

Relation: 2005 IEEE Asian Solid-State Circuits Conference

Immunomodulatory effect of splenectomy in lung cancer mouse xenograft models receiving radiation therapy.

Authors: Yeeun Kim, Changhoon Choi, Jee Hyun Park, Won-Gyun Ahn, Sung-Won Shin, Shin-Yeong Kim, Jae Myoung Noh

Source: Radiation Oncology Journal; Mar2022, Vol. 40 Issue 1, p53-65, 13p

Subject Terms: SPLENECTOMY, XENOGRAFTS, MYELOID-derived suppressor cells, LUNG cancer, NON-small-cell lung carcinoma, RADIOTHERAPY, LABORATORY mice

The Far East in Russia's Geopolitical Outlook. (cover story)

Authors: Sung-Won Shin¹, Taehwan Kim²

Source: Global Asia. Fall2014, Vol. 9 Issue 3, p52-57. 6p.

Subject Terms: *GEOPOLITICS, *INTERNATIONAL economic relations, RUSSIAN foreign relations, 1991-

Geographic Terms: EAST Asia

People: YELTSIN, Boris Nikolayevich, 1931-2007, PUTIN, Vladimir Vladimirovich, 1952-

EP-2029: Feasibility study of Fe3O4/TaOx nano particles as a radiosensitiser for radiation therapy

Authors: Sang Hee Ahn, A., Nohyun Lee, L., Sung Won Shin, S., Chang hoon Choi, C., Youngyih Han, H., Hee Chul Park, P., Doo Ho Choi, C.

Source: Radiotherapy and oncology. 119:S958-S958

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100034919769.0x000001&indx=1&recIds=ETOCvdc_100034919769.0x000001

Expression of fatty acid synthase is regulated by PGC-1α and contributes to increased cell proliferation.

Authors: SEONG-HOON YUN, SUNG-WON SHIN, JOO-IN PARK

Source: Oncology Reports; Dec2017, Vol. 38 Issue 6, p3497-3506, 10p

Immunomodulatory effect of captopril and local irradiation on myeloid-derived suppressor cells.

Authors: Won Kyung Cho¹, Sung-Won Shin¹, Shin-Yeong Kim¹, Chang-Won Hong², Changhoon Choi¹, Won Park¹, Jae Myoung Noh¹ rodrno@skku.edu

Source: Radiation Oncology Journal. 2016, Vol. 34 Issue 3, p223-229. 7p.

Subject Terms: *IMMUNOREGULATION, *CAPTOPRIL, *CANCER cells, *CANCER radiotherapy, *BIOMARKERS, *THERAPEUTICS

Adaptive Self Refresh Scheme for Battery Operated High-Density Mobile DRAM Applications.

Authors: Jin-Hong Ahn, Bong-Hwa Jeong, Saeng-Hwan Kim, Shin-Ho Chu, Sung-Kwon Cho, Han-Jin Lee, Min-Ho Kim, Sang-Il Park, Sung-Won Shin, Jun-Ho Lee, Bong-Seok Han, Jae-Keun Hong, Moran, P.B., Yong-Tak Kim

Source: 2006 IEEE Asian Solid-State Circuits Conference; 2006, p319-322, 4p

Overexpression of PGC-1α enhances cell proliferation and tumorigenesis of HEK293 cells through the upregulation of Sp1 and Acyl-CoA binding protein.

Authors: SUNG-WON SHIN, SEONG-HOON YUN, EUN-SEON PARK, JIN-SOOK JEONG, JONG-YOUNG KWAK, JOO-IN PARK

Source: International Journal of Oncology; 2015, Vol. 46 Issue 3, p1328-1342, 15p

Feasibility study of Fe3O4/TaO x nanoparticles as a radiosensitizer for proton therapy.

Authors: Sang Hee Ahn, Nohyun Lee, Changhoon Choi, Sung Won Shin, Youngyih Han, Hee Chul Park

Source: Physics in Medicine & Biology; Jun2018, Vol. 63 Issue 11, p1-1, 1p

Subject Terms: NANOPARTICLES, PROTON therapy, COMPUTED tomography