Serine/threonine kinase 31 promotes PDCD5‐mediated apoptosis in p53‐dependent human colon cancer cells

Authors: Kwak, Sungmin, Lee, Seung‐Hyun, Han, Eun‐Jung, Park, Soo‐Yeon, Jeong, Mi‐Hyeon, Seo, Jaesung, Park, Seung‐Ho, Sung, Gi‐Jun, Yoo, Jung‐Yoon, Yoon, Ho‐Geun, Choi, Kyung‐Chul

Source: Journal of cellular physiology. 234(3):2649-2658

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100136041494.0x000001&indx=1&recIds=ETOCvdc_100136041494.0x000001

Novel TGF‐β1 inhibitor antagonizes TGF‐β1‐induced epithelial‐mesenchymal transition in human A549 lung cancer cells

Authors: Jeong, Ji‐Hoon, Jang, Hae Jin, Kwak, Sungmin, Sung, Gi‐Jun, Park, Seung‐Ho, Song, Ji‐Hye, Kim, Hyunhee, Na, Younghwa, Choi, Kyung‐Chul

Source: Journal of cellular biochemistry. 120(1):977-987

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100125729443.0x000001&indx=1&recIds=ETOCvdc_100125729443.0x000001

DNAJB1 destabilizes PDCD5 to suppress p53-mediated apoptosis

Authors: Cui, Xiandan, Choi, Hyo-Kyoung, Choi, Young-Seok, Park, Soo-Yeon, Sung, Gi-Jun, Lee, Yoo-Hyun, Lee, Jeongmin, Jun, Woo Jin, Kim, Kyungsup, Choi, Kyung-Chul ^*, Yoon, Ho-Geun ^**

Source: In Cancer Letters 1 February 2015 357(1):307-315

Evaluation of Synergistic Anti-Leukemic Efficacy of PHI-101 in Preclinical Model of FLT3-ITD Acute Myeloid Leukemia

Authors: Sung, Gi-Jun, Kim, Kyung-Ah, Nam, Ky-Youb, Kim, Kyu-Tae, Han, June, Yoon, JeongHyeok, Li, Li, Nguyen, Bao, Seale, Tessa, Small, Donald

Source: In Blood 2 November 2023 142 Supplement 1:5949-5949

PHI-101 As a Potent Next-Generation FLT3 Inhibitor, Overcome Resistances in Previously Treated Patients with FLT3-ITD or TKD Acute Myeloid Leukemia: Results of a Phase Ia/Ib Clinical Trial

Authors: Yoon, Sung-Soo, Shin, Dongyeop, Lee, Je-Hwan, Jang, Jun Ho, Cheong, June-Won, Shin, Ho-Jin, Lee, Jeong-Ok, Lee, Yoo Jin, Clarey, Joseph, Sung, Gi-Jun, Kim, Kyung-Ah, Nam, Ky-Youb, Kim, Kyu-Tae, Han, June, Yoon, JeongHyeok, Nguyen, Bao, Li, Li, Small, Donald

Source: In Blood 2 November 2023 142 Supplement 1:4283-4283

miR-3189-targeted GLUT3 repression by HDAC2 knockdown inhibits glioblastoma tumorigenesis through regulating glucose metabolism and proliferation.

Authors: Kwak, Sungmin, Park, Seung-Ho, Kim, Sung-Hak, Sung, Gi-Jun, Song, Ji-Hye, Jeong, Ji-Hoon, Kim, Hyunhee, Ha, Chang Hoon, Kim, Seong Who, Choi, Kyung-Chul

Source: Journal of Experimental & Clinical Cancer Research (17569966); 3/8/2022, Vol. 41 Issue 1, p1-18, 18p

Subject Terms: LACTATES, GLUCOSE metabolism, METHYLGUANINE, GLIOBLASTOMA multiforme, CELL metabolism, NEOPLASTIC cell transformation, NEUROLOGICAL disorders

SIRT1 plays an important role in implantation and decidualization during mouse early pregnancy

Authors: Hwang, Yeon Jeong, Sung, Gi-Jun, Marquardt, Ryan, Young, Steven L, Lessey, Bruce A, Kim, Tae Hoon, Cheon, Yong-Pil, Jeong, Jae-Wook

Source: Biology of Reproduction; June 2022, Vol. 106 Issue: 6 p1072-1082, 11p

Epigenetic regulation of p62/SQSTM1 overcomes the radioresistance of head and neck cancer cells via autophagy-dependent senescence induction.

Authors: Lee, Myungjin, Nam, Hae Yun, Kang, Hee-Bum, Lee, Won Hyeok, Lee, Geun-Hee, Sung, Gi-Jun, Han, Myung Woul, Cho, Kyung-Ja, Chang, Eun-Ju, Choi, Kyung-Chul, Kim, Seong Who, Kim, Sang Yoon

Source: Cell Death & Disease; Mar2021, Vol. 12 Issue 3, p1-14, 14p

Small-molecule inhibitors of histone deacetylase improve CRISPR-based adenine base editing.

Authors: Shin, Ha Rim, See, Ji-Eun, Kweon, Jiyeon, Kim, Heon Seok, Sung, Gi-Jun, Park, Sojung, Jang, An-Hee, Jang, Gayoung, Choi, Kyung‐Chul, Kim, Inki, Kim, Jin-Soo, Kim, Yongsub

Source: Nucleic Acids Research; 2/26/2021, Vol. 49 Issue 4, p2390-2399, 10p

Targeting CPT1A enhances metabolic therapy in human melanoma cells with the BRAF V600E mutation

Authors: Sung, Gi-Jun, Choi, Hyo-Kyoung, Kwak, Sungmin, Song, Ji-Hye, Ko, Hyeonseok, Yoon, Ho-Geun, Kang, Hee-Bum, Choi, Kyung-Chul

Source: In International Journal of Biochemistry and Cell Biology December 2016 81 Part A:76-81

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TNFα Enhances Tamoxifen Sensitivity through Dissociation of ERα-p53-NCOR1 Complexes in ERα-Positive Breast Cancer.

Authors: Kim, Hyunhee, Park, Seung-Ho, Lee, Jangho, Sung, Gi-Jun, Song, Ji-Hye, Kwak, Sungmin, Jeong, Ji-Hoon, Kong, Min-Jeong, Hwang, Jin-Taek, Choi, Hyo-Kyoung, Choi, Kyung-Chul

Source: Cancers; Jun2021, Vol. 13 Issue 11, p2601, 1p

Subject Terms: IN vitro studies, PROMOTERS (Genetics), XENOGRAFTS, COMBINATION drug therapy, ANIMAL experimentation, NUCLEAR proteins, APOPTOSIS, TUMOR necrosis factors, TAMOXIFEN, CELL lines, TRANSCRIPTION factors, HORMONE receptor positive breast cancer, PHARMACODYNAMICS

TFEB Supports Pancreatic Cancer Growth through the Transcriptional Regulation of Glutaminase.

Authors: Kim, Ji Hye, Lee, Jinyoung, Cho, Young-Ra, Lee, So-Yeon, Sung, Gi-Jun, Shin, Dong-Myung, Choi, Kyung-Chul, Son, Jaekyoung, Pozza, Elisa Dalla, Dando, Ilaria

Source: Cancers; Feb2021, Vol. 13 Issue 3, p483, 1p

Subject Terms: AUTOPHAGY, AMIDASES, CELL lines, CONVALESCENCE, DIETARY supplements, GENE expression, MITOCHONDRIA, PANCREATIC tumors, PANCREATIC duct, TRANSCRIPTION factors, DISEASE progression, DUCTAL carcinoma, IN vitro studies, IN vivo studies

A New TGF-β1 Inhibitor, CTI-82, Antagonizes Epithelial–Mesenchymal Transition through Inhibition of Phospho-SMAD2/3 and Phospho-ERK.

Authors: Jeong, Ji-Hoon, Kim, Hyunhee, Park, Seung-Ho, Park, Hayeon, Jeong, Minseok, Kwak, Sungmin, Sung, Gi-Jun, Song, Ji-Hye, Na, Younghwa, Choi, Kyung-Chul

Source: Biology (2079-7737); Jul2020, Vol. 9 Issue 7, p143, 1p

Subject Terms: EPITHELIAL-mesenchymal transition, CANCER invasiveness, CELL migration, TUMOR growth, CANCER cells

EGFR–c-Src-Mediated HDAC3 Phosphorylation Exacerbates Invasion of Breast Cancer Cells.

Authors: Kwak, Sung-Min, Seo, Jaesung, Hwang, Jin-Taek, Sung, Gi-Jun, Song, Ji-Hye, Jeong, Ji-Hoon, Lee, Seung-Hyun, Yoon, Ho-Geun, Choi, Hyo-Kyoung, Choi, Kyung-Chul

Source: Cells (2073-4409); Aug2019, Vol. 8 Issue 8, p930-930, 1p

Subject Terms: CANCER cells, BREAST cancer, EPIDERMAL growth factor receptors, PHOSPHORYLATION, HISTONE deacetylase