Selective targeting of chemically modified miR-34a to prostate cancer using a small molecule ligand and an endosomal escape agent

Authors: Abdelaal, Ahmed M., Sohal, Ikjot S., Iyer, Shreyas G., Sudarshan, Kasireddy, Orellana, Esteban A., Ozcan, Kenan E., dos Santos, Andrea P., Low, Philip S., Kasinski, Andrea L.

Source: In Molecular Therapy - Nucleic Acids 11 June 2024 35(2)

Use of a universal targeting CAR T cell to simultaneously kill cancer cells and cancer-associated fibroblasts.

Authors: Huang, Bo, Zheng, Suilan, Sudarshan, Kasireddy, Mukkamala, Ramesh, Srinivasarao, Madduri, Sardesai, Tushar, Yang, Xiaofei, Chu, Haiyan, Low, Philip S.

Source: Frontiers in Immunology; 2025, p1-11, 11p

Subject Terms: CHIMERIC antigen receptors, T cells, EXTRACELLULAR matrix, CANCER cells, FIBROBLASTS

Newly Green Synthesized ZnO Nanoparticles and their Effective Influence on Photocatalytic and Antimicrobial Activities.

Authors: Rathaiah, Mamilla, Venkataramana, Badineni, Sudarshan, Kasireddy, Naidu, Boya Vijaya Kumar

Source: ChemistrySelect; 2/19/2025, Vol. 10 Issue 7, p1-12, 12p

Salsoline derivatives, genistein, semisynthetic derivative of kojic acid, and naringenin as inhibitors of A42R profilin-like protein of monkeypox virus: in silico studies.

Authors: Chebaibi, Mohamed, Bourhia, Mohammed, ez-zahra Amrati, Fatima, Slighoua, Meryem, Mssillou, Ibrahim, Aboul-Soud, Mourad A. M., Khalid, Asaad, Hassani, Rym, Bousta, Dalila, Achour, Sanae, Benhida, Rachid, Daoud, Rachid, Sudarshan, Kasireddy, Aggarwal, Navidha

Source: Frontiers in Chemistry; 2024, p01-15, 15p

Subject Terms: MOLECULAR biology, MOLECULAR dynamics, MONKEYPOX, HYDROGEN analysis, MOLECULAR genetics

Recent Advances in the Synthesis of Diarylheptanoids.

Authors: Sudarshan, Kasireddy (AUTHOR) kasireddysudarshan@gmail.com, Yarlagadda, Suresh (AUTHOR), Sengupta, Sagnik (AUTHOR)

Source: Chemistry - An Asian Journal. Aug2024, Vol. 19 Issue 15, p1-30. 30p.

Subject Terms: *NATURAL products, *METATHESIS reactions, *ALKENES, *CHEMISTS, *CURCUMIN

Discovery of an isocoumarin analogue that modulates neuronal functions via neurotrophin receptor TrkB

Authors: Sudarshan, Kasireddy, Boda, Arun kumar, Dogra, Shalini, Bose, Ishani, Yadav, Prem Narayan, Aidhen, Indrapal Singh

Source: Bioorganic & medicinal chemistry letters. 29(4):585-590

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100075574558.0x000001&indx=1&recIds=ETOCvdc_100075574558.0x000001

Developing Folate-Conjugated miR-34a Therapeutic for Prostate Cancer: Challenges and Promises.

Authors: Li, Wen, Wang, Yunfei, Liu, Xiaozhuo, Wu, Shan, Wang, Moyi, Turowski, Steven G., Spernyak, Joseph A., Tracz, Amanda, Abdelaal, Ahmed M., Sudarshan, Kasireddy, Puzanov, Igor, Chatta, Gurkamal, Kasinski, Andrea L., Tang, Dean G.

Source: International Journal of Molecular Sciences; Feb2024, Vol. 25 Issue 4, p2123, 19p

Subject Terms: ANDROGEN receptors, PROSTATE cancer, CANCER stem cells, LUNG cancer, CANCER cells, DRUG resistance, T cells

Inhibition of the enzymes in the leukotriene and prostaglandin pathways in inflammation by 3-aryl isocoumarins

Authors: Ramanan, Meera, Sinha, Shweta, Sudarshan, Kasireddy, Aidhen, Indrapal Singh, Doble, Mukesh

Source: European journal of medicinal chemistry. 124:428-434

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100062665998.0x000001&indx=1&recIds=ETOCvdc_100062665998.0x000001

A first-in-class fully modified version of miR-34a with outstanding stability, activity, and anti-tumor efficacy

Authors: Abdelaal, Ahmed M., Sohal, Ikjot S., Iyer, Shreyas, Sudarshan, Kasireddy, Kothandaraman, Harish, Lanman, Nadia A., Low, Philip S., Kasinski, Andrea L.

Source: Oncogene; September 2023, Vol. 42 Issue: 40 p2985-2999, 15p

This result is not displayed to guests.
Login for full access.

Development of a simple high-throughput assay for directed evolution of enantioselective sulfoxide reductases.

Authors: Tarallo, Vincenzo¹ (AUTHOR), Sudarshan, Kasireddy¹ (AUTHOR), Nosek, Vladimír¹ (AUTHOR), Míšek, Jiří¹ (AUTHOR) misek@natur.cuni.cz

Source: Chemical Communications. 5/18/2020, Vol. 56 Issue 40, p5386-5388. 3p.

Subject Terms: *REDUCTASES, *METHIONINE sulfoxide reductase, *BIOLOGICAL evolution

This result is not displayed to guests.
Login for full access.

This result is not displayed to guests.
Login for full access.

This result is not displayed to guests.
Login for full access.

Bio-mediated green synthesis of copper oxide nanoparticles using plant extract and its applications to optical switching in nonlinear optics.

Authors: Ariyamuthu, Rajabhuvaneswari¹ (AUTHOR), G., Murali² (AUTHOR), Arumugam, Natarajan³ (AUTHOR), Almansour, Abdulrahman I.³ (AUTHOR), Sudarshan, Kasireddy⁴ (AUTHOR), S., Jeyaram⁵ (AUTHOR) jeyaram.msc@gmail.com

Source: Particulate Science & Technology. Mar2025, p1-7. 7p. 3 Illustrations.

Subject Terms: *OPTICAL saturable absorption, *NONLINEAR optics, *SCANNING electron microscopy, *OPTICAL switching, *MORINDA citrifolia

ChemInform Abstract: Synthesis of 3-Arylisocoumarins by Using Acyl Anion Chemistry and Synthesis of Thunberginol A and Cajanolactone A.

Authors: Sudarshan, Kasireddy¹, Manna, Manash Kumar¹, Aidhen, Indrapal Singh¹

Source: ChemInform. Jul2015, Vol. 46 Issue 28, pno-no. 1p.

Subject Terms: *ACYL anions, *CHEMICAL synthesis, *ANION synthesis, *COUMARINS, *HETEROCYCLIC compounds synthesis, *CARBON-carbon bonds

Nonlinear Optical Features of Phenol Red Dye in Different Solvent Media Using Z-scan and Density Functional Theory.

Authors: Anusha, B. (AUTHOR), Dileepan, A. G. Bharathi (AUTHOR), Ramasamy, Rohith (AUTHOR), Solomon, Rajadurai Vijay (AUTHOR), Arumugam, Natarajan (AUTHOR), Almansour, Abdulrahman I. (AUTHOR), Sudarshan, Kasireddy (AUTHOR), Jeyaram, S.¹ (AUTHOR) jeyaram.msc@gmail.com

Source: Journal of Fluorescence. Mar2025, p1-14.

Observation of Fascinating Nonlinear Optical Features of Fluorescent Dye in Selected Polar Solvents by Z-Scan and DFT Method.

Authors: Priyadharsini, K. (AUTHOR), Dileepan, A. G. Bharathi (AUTHOR), Ramasamy, Rohith (AUTHOR), Solomon, Rajadurai Vijay (AUTHOR), Arumugam, Natarajan (AUTHOR), Almansour, Abdulrahman I. (AUTHOR), Sudarshan, Kasireddy (AUTHOR), Jeyaram, S.¹ (AUTHOR) jeyaram.msc@gmail.com

Source: Journal of Fluorescence. Feb2025, p1-12.

DFT and Z-scan Studies for the Determination of Nonlinear Optical Susceptibility and Second Order Hyperpolarizability of Ethidium Bromide Dye in Different Solvents.

Authors: Deepa, C. (AUTHOR), Dileepan, A. G. Bharathi (AUTHOR), Ramasamy, Rohith (AUTHOR), Solomon, Rajadurai Vijay (AUTHOR), Arumugam, Natarajan (AUTHOR), Almansour, Abdulrahman I. (AUTHOR), Sudarshan, Kasireddy (AUTHOR), Jeyaram, S.¹ (AUTHOR) jeyaram.msc@gmail.com

Source: Journal of Fluorescence. Feb2025, p1-13.