AP3B1 Has Type I Interferon-Independent Antiviral Function against SARS-CoV-2.

Authors: Subramanian, Gayatri¹ (AUTHOR), Hage, Adam² (AUTHOR), Feldmann, Friederike³ (AUTHOR), Chiramel, Abhilash I.¹ (AUTHOR), McNally, Kristin L.¹ (AUTHOR), Sturdevant, Gail L.^1,2 (AUTHOR), Beare, Paul A.⁴ (AUTHOR), Best, Sonja M.^1,2 (AUTHOR) sbest@niaid.nih.gov

Source: Viruses (1999-4915). Sep2024, Vol. 16 Issue 9, p1377. 11p.

Subject Terms: *SARS-CoV-2, *VIRAL genes, *VIRAL proteins, *VIRAL replication

Autophagic degradation of IRF3 induced by the small-molecule auranofin inhibits its transcriptional and proapoptotic activities

Authors: Glanz, Anna, Chakravarty, Sukanya, Fan, Shumin, Chawla, Karan, Subramanian, Gayatri, Rahman, Tia, Walters, Dean, Chakravarti, Ritu, Chattopadhyay, Saurabh

Source: In Journal of Biological Chemistry November 2021 297(5)

Mitophagy antagonism by ZIKV reveals Ajuba as a regulator of PINK1 signaling, PKR-dependent inflammation, and viral invasion of tissues

Authors: Ponia, Sanket S., Robertson, Shelly J., McNally, Kristin L., Subramanian, Gayatri, Sturdevant, Gail L., Lewis, Matthew, Jessop, Forrest, Kendall, Catherine, Gallegos, Dylan, Hay, Arielle, Schwartz, Cindi, Rosenke, Rebecca, Saturday, Greg, Bosio, Catherine M., Martens, Craig, Best, Sonja M.

Source: In Cell Reports 26 October 2021 37(4)

The interferon-inducible protein TDRD7 inhibits AMP-activated protein kinase and thereby restricts autophagy-independent virus replication

Authors: Subramanian, Gayatri, Popli, Sonam, Chakravarty, Sukanya, Taylor, R. Travis, Chakravarti, Ritu, Chattopadhyay, Saurabh

Source: In Journal of Biological Chemistry 15 May 2020 295(20):6811-6822

Red Sox versus Yankees: Sports Team Rivalry, Sports Symbols, and Distance Performance

Authors: Yoon, Sukki, Kim, Kacy, Beltis, A. J., Logan, John, Subramanian, Gayatri

Source: Journal of global sport management. 5(3):308-319

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100111043956.0x000001&indx=1&recIds=ETOCvdc_100111043956.0x000001

A new mechanism of interferon’s antiviral action: Induction of autophagy, essential for paramyxovirus replication, is inhibited by the interferon stimulated gene, TDRD7.

Authors: Subramanian, Gayatri¹, Kuzmanovic, Teodora², Zhang, Ying², Peter, Cara Beate³, Veleeparambil, Manoj², Chakravarti, Ritu³, Sen, Ganes C.², Chattopadhyay, Saurabh^1,2 Saurabh.Chattopadhyay@UToledo.edu

Source: PLoS Pathogens. 1/30/2018, Vol. 14 Issue 1, p1-25. 25p.

Subject Terms: *INTERFERONS, *AUTOPHAGY, *VIRUS diseases, *PARAMYXOVIRUSES, *SENDAI virus

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Gene Therapy Leaves a Vicious Cycle.

Authors: Goswami, Reena, Subramanian, Gayatri, Silayeva, Liliya, Newkirk, Isabelle, Doctor, Deborah, Chawla, Karan, Chattopadhyay, Saurabh, Chandra, Dhyan, Chilukuri, Nageswararao, Betapudi, Venkaiah

Source: Frontiers in Oncology; 4/24/2019, pN.PAG-N.PAG, 25p

Subject Terms: GENE therapy, GENETIC code, PROTEIN synthesis, CLINICAL trials, PHARMACEUTICAL industry

Automating component-based system assembly.

Authors: Manolios, Panagiotis, Vroon, Daron, Subramanian, Gayatri

Source: Proceedings of the 2007 International Symposium: Software Testing & Analysis; 7/ 9/2007, p61-72, 12p

High Throughput Screening of FDA-Approved Drug Library Reveals the Compounds that Promote IRF3-Mediated Pro-Apoptotic Pathway Inhibit Virus Replication.

Authors: Glanz, Anna, Chawla, Karan, Fabry, Stephanie, Subramanian, Gayatri, Garcia, Julie, Jay, Bryanna, Ciricillo, Jacob, Chakravarti, Ritu, Taylor, R. Travis, Chattopadhyay, Saurabh

Source: Viruses (1999-4915); Apr2020, Vol. 12 Issue 4, p442-442, 1p

Subject Terms: VIRAL replication, SMALL molecules, VESICULAR stomatitis, ANTIVIRAL agents, EXTRACELLULAR signal-regulated kinases, TYPE I interferons

Company/Entity: UNITED States. Food & Drug Administration