Oxidized phospholipid and transcriptomic signatures of THC-related vaping associated lung injury.

Authors: Suber, Tomeka L.¹ (AUTHOR) subertl2@upmc.edu, Tabary, Mohammadreza¹ (AUTHOR), Bain, William^1,2 (AUTHOR), Olonisakin, Tolani³ (AUTHOR), Lockwood, Karina¹ (AUTHOR), Xiong, Zeyu⁴ (AUTHOR), Zhang, Yingze¹ (AUTHOR), Kohli, Naina⁵ (AUTHOR), Furguiele, Lauren⁶ (AUTHOR), Peñaloza, Hernán^7,8 (AUTHOR), McVerry, Bryan J.¹ (AUTHOR), Rose, Jason J.⁹ (AUTHOR), Shah, Faraaz^1,2 (AUTHOR), Methé, Barbara¹ (AUTHOR), Li, Kelvin¹ (AUTHOR), Mallampalli, Rama K.¹⁰ (AUTHOR), Chen, Kong¹ (AUTHOR), Fan, Li¹ (AUTHOR), Morris, Alison¹ (AUTHOR), Tyurin, Vladimir A.¹¹ (AUTHOR)

Source: Scientific Reports. 12/30/2024, Vol. 14 Issue 1, p1-15. 15p.

Subject Terms: *LUNG injuries, *E-cigarette or vaping product use-associated lung injuries, *PHYSIOLOGICAL oxidation, *ARACHIDONIC acid, *OLEIC acid

Trajectories of Host-Response Subphenotypes in Patients With COVID-19 Across the Spectrum of Respiratory Support

Authors: Lu, Michael, Drohan, Callie, Bain, William, Shah, Faraaz A., Bittner, Matthew, Evankovich, John, Prendergast, Niall T., Hensley, Matthew, Suber, Tomeka L., Fitzpatrick, Meghan, Ramanan, Raj, Murray, Holt, Schaefer, Caitlin, Qin, Shulin, Wang, Xiaohong, Zhang, Yingze, Nouraie, Seyed M., Gentry, Heather, Murray, Cathy, Patel, Asha, Macatangay, Bernard J., Jacobs, Jana, Mellors, John W., Lee, Janet S., Ray, Prabir, Ray, Anuradha, Methé, Barbara, Morris, Alison, McVerry, Bryan J., Kitsios, Georgios D.

Source: In CHEST Critical Care December 2023 1(3)

Rationale and design of the Prone Position and Respiratory Outcomes in Non-intubated COVID-19 PatiEnts: The “PRONE” Study

Authors: Friedman, Eugene, Franzone, John, Ko, Emily R., Corey, Kristin, Mock, Jason, Alavian, Naseem, Schwartz, Adam, Drummond, M. Bradley, Suber, Tomeka, Linstrum, Kelsey, Bain, William, Castiblanco, Saramaria Afanador, Zak, Martin, Zaeh, Sandra, Gupta, Ishaan, Damarla, Mahendra, Punjabi, Naresh M.

Source: In Contemporary Clinical Trials October 2021 109

Considerations for Racial Diversity in the Cardiology Workforce in the United States of America

Authors: Johnson, Amber E., Birru Talabi, Mehret, Bonifacino, Eliana, Culyba, Alison J., Jonassaint, Naudia L., Nance, Melonie A., Napoé, G. Sarah, Olafiranye, Oladipupo, Owusu-Ansah, Sylvia, Suber, Tomeka L.

Source: Journal of the American College of Cardiology. 77(15):1934-1937

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100141217123.0x000001&indx=1&recIds=ETOCvdc_100141217123.0x000001

IL‐37‐induced activation of glycogen synthase kinase 3β promotes IL‐1R8/Sigirr phosphorylation, internalization, and degradation in lung epithelial cells

Authors: Li, Lian, Wei, Jianxin, Suber, Tomeka L., Ye, Qinmao, Miao, Jiaxing, Li, Shuang, Taleb, Sarah J., Tran, Kevin C., Tamaskar, Arya S., Zhao, Jing, Zhao, Yutong

Source: Journal of cellular physiology. 236(8):5676-5685

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100130981134.0x000001&indx=1&recIds=ETOCvdc_100130981134.0x000001

Racial Diversity Among American Cardiologists

Authors: Johnson, Amber E., Talabi, Mehret Birru, Bonifacino, Eliana, Culyba, Alison J., Davis, Esa M., Davis, Paula K., De Castro, Laura M., Essien, Utibe R., Maria Gonzaga, Alda, Hogan, MaCalus V., James, Alaina J., Jonassaint, Charles R., Jonassaint, Naudia L., Matheo, Loreta, Nance, Melonie A., Napoé, G. Sarah, Olafiranye, Oladipupo, Owusu-Ansah, Sylvia, Pierson-Brown, Tomar N., Conrad Smith, A.J., Suber, Tomeka L., Torres, Orquidia, Tripp, Rickquel, Ufomata, Eloho, Wilson, J. Deanna, South-Paul, Jeannette E.

Source: Circulation. 143(24):2395-2405

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100189142810.0x000001&indx=1&recIds=ETOCvdc_100189142810.0x000001

Clinical and biologic profiles of patients with acute respiratory distress syndrome by prevalence of chronic obstructive pulmonary disease or emphysema; a cohort study.

Authors: Nath, Sridesh, Qurashi, Hafiz, Kitsios, Georgios D., Bain, William, Aneis, Hamam, Suber, Tomeka, Prendergast, Niall, Hensley, Matthew, Schaefer, Caitlin, Zhang, Yingze, Bon, Jessica, McVerry, Bryan J., Evankovich, John, Shah, Faraaz Ali

Source: Respiratory Research; 11/8/2024, Vol. 25 Issue 1, p1-11, 11p

Subject Terms: PULMONARY emphysema, ADULT respiratory distress syndrome, CHRONIC obstructive pulmonary disease, CONGESTIVE heart failure, INTENSIVE care units

Serum metabolomic signatures of fatty acid oxidation defects differentiate host-response subphenotypes of acute respiratory distress syndrome.

Authors: Suber, Tomeka L.^1,2 (AUTHOR) subertl2@upmc.edu, Wendell, Stacy G.³ (AUTHOR), Mullett, Steven J.³ (AUTHOR), Zuchelkowski, Benjamin¹ (AUTHOR), Bain, William^1,2,4 (AUTHOR), Kitsios, Georgios D.^1,2 (AUTHOR), McVerry, Bryan J.^1,2 (AUTHOR), Ray, Prabir^1,2 (AUTHOR), Ray, Anuradha^1,2 (AUTHOR), Mallampalli, Rama K.⁵ (AUTHOR), Zhang, Yingze¹ (AUTHOR), Shah, Faraaz^1,2,4 (AUTHOR), Nouraie, Seyed Mehdi¹ (AUTHOR), Lee, Janet S.⁶ (AUTHOR)

Source: Respiratory Research. 5/20/2023, Vol. 24 Issue 1, p1-16. 16p.

Subject Terms: *ADULT respiratory distress syndrome, *FATTY acid oxidation, *METABOLOMICS

SCFFBXO17 E3 ligase modulates inflammation by regulating proteasomal degradation of glycogen synthase kinase-3β in lung epithelia

Authors: Suber, Tomeka, Wei, Jianxin, Jacko, Anastasia M., Nikolli, Ina, Zhao, Yutong, Zhao, Jing, Mallampalli, Rama K.

Source: In Journal of Biological Chemistry 5 March 2017 292(18):7452-7461

FBXO17 promotes cell proliferation through activation of Akt in lung adenocarcinoma cells

Authors: Suber, Tomeka, Nikolli, Ina, O'Brien, Michael, Londino, James, Zhao, Jing, Chen, Kong, Mallampalli, Rama, Zhao, Yutong

Source: Respiratory research. 19(1):1-11

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100184329113.0x000001&indx=1&recIds=ETOCvdc_100184329113.0x000001

6 COVID-19 treatments helping patients survive (Mar. 2021)

Authors: Bain William G., Kitsios Georgios D., Suber Tomeka L.

Source: The Conversation: An Independent Source of Analysis from Academic Researchers.

Availability: https://search.credoreference.com/content/entry/conversqauq/6_covid19_treatments_helping_patients_survive/0

Glucocorticoid use in acute respiratory failure from pulmonary causes and association with early changes in the systemic host immune response.

Authors: Al-Yousif, Nameer, Nouraie, Seyed M., Broerman, Matthew J., Zhang, Yingze, Suber, Tomeka L., Evankovich, John, Bain, William G., Kitsios, Georgios D., McVerry, Bryan J., Shah, Faraaz A.

Source: Intensive Care Medicine Experimental; 3/5/2024, Vol. 12 Issue 1, p1-11, 11p

Subject Terms: ADULT respiratory distress syndrome, PREMATURE menopause, IMMUNE response, GLUCOCORTICOIDS, IMMUNOSUPPRESSIVE agents

Company/Entity: UNIVERSITY of Pittsburgh

Nitro-oleic acid attenuates pro-inflammatory metabolic signaling in LPS activated macrophages

Authors: Uvalle, Crystal, Gelhaus, Stacy, Fong, Erica, Mullett, Steve, Lockwood, Karina, Suber, Tomeka

Source: In Free Radical Biology and Medicine 1 November 2023 208 Supplement 1:S78-S78

Structural basis of IAP recognition by SMAC/DIABLO.

Authors: Wu, Geng, Chai, Jijie, Suber, Tomeka L.

Source: Nature; December 21-28 2000, Vol. 408 Issue 6815, p1008-1012, 5p

COVID-19 versus Non-COVID-19 Acute Respiratory Distress Syndrome: Comparison of Demographics, Physiologic Parameters, Inflammatory Biomarkers, and Clinical Outcomes.

Authors: Bain, William, Haopu Yang, Shah, Faraaz Ali, Suber, Tomeka, Drohan, Callie, Al-Yousif, Nameer, DeSensi, Rebecca S., Bensen, Nicole, Schaefer, Caitlin, Rosborough, Brian R., Somasundaram, Ashwin, Workman, Creg J., Lampenfeld, Caleb, Cillo, Anthony R., Cardello, Carly, Feng Shan, Bruno, Tullia C., Vignali, Dario A. A., Ray, Prabir, Ray, Anuradha

Source: Annals of the American Thoracic Society; Jul2021, Vol. 18 Issue 7, p1202-1210, 9p

Subject Terms: ADULT respiratory distress syndrome, COVID-19, CORONAVIRUS diseases, PNEUMONIA, ARTIFICIAL respiration

A no-Wnt situation for alveolar macrophage self-renewal

Authors: Suber, Tomeka, Camiolo, Matthew J., Ray, Anuradha

Source: In Immunity 8 June 2021 54(6):1099-1101

Stressed erythrophagocytosis induces immunosuppression during sepsis through heme-mediated STAT1 dysregulation.

Authors: Olonisakin, Tolani F.^1,2,3, Suber, Tomeka^2,3, Gonzalez-Ferrer, Shekina^2,3, Zeyu Xiong^2,3, Peñaloza, Hernán F.^2,3, van der Geest, Rick^2,3, Yuting Xiong^2,3, Osei-Hwedieh, David O.³, Tejero, Jesús^3,4, Rosengart, Matthew R.⁵, Mars, Wendy M.⁶, Van Tyne, Daria⁷, Perlegas, Andreas⁸, Brashears, Samuel⁸, Kim-Shapiro, Daniel B.⁸, Gladwin, Mark T.^3,4, Bachman, Michael A.⁹, Hod, Eldad A.¹⁰, St. Croix, Claudette¹¹, Tyurina, Yulia Y.^12,13

Source: Journal of Clinical Investigation. Jan2021, Vol. 131 Issue 1, p1-17. 17p.

Subject Terms: *SEPSIS, *KLEBSIELLA infections, *HEME, *KLEBSIELLA pneumoniae, *IMMUNOSUPPRESSION, *PHAGOCYTOSIS, *MOLECULAR mechanisms of immunosuppression, *IMMUNOLOGICAL tolerance, *RESEARCH, *ANIMAL experimentation, *RESEARCH methodology, *METALLOPORPHYRINS, *MEDICAL cooperation, *EVALUATION research, *COMPARATIVE studies, *GENES, *RESEARCH funding, *ERYTHROCYTES, *CARRIER proteins, *MICE

Tumor necrosis factor-α regulates skeletal myogenesis by inhibiting SP1 interaction with cis-acting regulatory elements within the Fbxl2 gene promoter.

Authors: O'Brien, Michael E., Londino, James, McGinnis, Marcus, Weathington, Nathaniel, Adair, Jessica, Suber, Tomeka, Kagan, Valerian, Kong Chen, Chunbin Zou, Chen, Bill, Bon, Jessica, Mallampalli, Rama K.

Source: Molecular & Cellular Biology; Jun2020, Vol. 40 Issue 12, p1-53, 53p

Subject Terms: MYOBLASTS, NF-kappa B, UBIQUITIN ligases, MYOGENESIS, CELL cycle, BASE pairs, GENE silencing

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AM966, an Antagonist of Lysophosphatidic Acid Receptor 1, Increases Lung Microvascular Endothelial Permeability through Activation of Rho Signaling Pathway and Phosphorylation of VE-Cadherin

Authors: Cai, Junting, Wei, Jianxin, Li, Shuang, Suber, Tomeka, Zhao, Jing

Source: Mediators of inflammation. 2017(2):6893560-6893560

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN611525587&indx=1&recIds=ETOCRN611525587