Applying HDACis to increase SSTR2 expression and radiolabeled DOTA-TATE uptake: from cells to mice

Authors: Klomp, Maria J., van den Brink, Lilian, van Koetsveld, Peter M., de Ridder, Corrina M.A., Stuurman, Debra C., Löwik, Clemens W.G.M., Hofland, Leo J., Dalm, Simone U.

Source: In Life Sciences 1 December 2023 334

In Vivo Evaluation of Indium-111–Labeled 800CW as a Necrosis-Avid Contrast Agent

Authors: Stroet, Marcus C. M., de Blois, Erik, Stuurman, Debra C., de Ridder, Corrina M. A., Haeck, Joost, Seimbille, Yann, Mezzanotte, Laura, de Jong, Marion, Löwik, Clemens W. G. M., Panth, Kranthi M.

Source: Molecular imaging and biology. 22(5):1333-1341

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100171781699.0x000001&indx=1&recIds=ETOCvdc_100171781699.0x000001

Rapid Assessment of Bio-distribution and Antitumor Activity of the Photosensitizer Bremachlorin in a Murine PDAC Model: Detection of PDT-induced Tumor Necrosis by IRDye® 800CW Carboxylate, Using Whole-Body Fluorescent Imaging.

Authors: McMorrow, Roisin, de Bruijn, Henriette S., Que, Ivo, Stuurman, Debra C., de Ridder, Corrina M.A., Doukas, Michail, Robinson, Dominic J., Mezzanotte, Laura, Lowik, Clemens W.G.M.

Source: Molecular Imaging & Biology; Aug2024, Vol. 26 Issue 4, p616-627, 12p

Subject Terms: PHOTOSENSITIZERS, ANTINEOPLASTIC agents, PHOTODYNAMIC therapy, CYANINES, PANCREATIC duct, CELL death, NECROSIS

In vitro and in vivo analyses of eFAP: a novel FAP-targeting small molecule for radionuclide theranostics and other oncological interventions.

Authors: van der Heide, Circe D., Ma, Hanyue, Hoorens, Mark W.H., Campeiro, Joana D., Stuurman, Debra C., de Ridder, Corrina M.A., Seimbille, Yann, Dalm, Simone U.

Source: EJNMMI Radiopharmacy & Chemistry; 7/29/2024, Vol. 9 Issue 1, p1-17, 17p

Subject Terms: RADIONUCLIDE imaging, SMALL molecules, CONFOCAL microscopy, PHARMACOPHORE, COMPANION diagnostics

Viability Analysis and High-Content Live-Cell Imaging for Drug Testing in Prostate Cancer Xenograft-Derived Organoids.

Authors: Van Hemelryk, Annelies, Erkens-Schulze, Sigrun, Lim, Lifani, de Ridder, Corrina M. A., Stuurman, Debra C., Jenster, Guido W., van Royen, Martin E., van Weerden, Wytske M.

Source: Cells (2073-4409); May2023, Vol. 12 Issue 10, p1377, 16p

Subject Terms: DRUG use testing, PROSTATE cancer, ORGANOIDS, ENDORECTAL ultrasonography, CELL nuclei, PROPIDIUM iodide

Pre- and Intraoperative Visualization of GRPR-Expressing Solid Tumors: Preclinical Profiling of Novel Dual-Modality Probes for Nuclear and Fluorescence Imaging.

Authors: Verhoeven, Marjolein, Handula, Maryana, van den Brink, Lilian, de Ridder, Corrina M. A., Stuurman, Debra C., Seimbille, Yann, Dalm, Simone U.

Source: Cancers; Apr2023, Vol. 15 Issue 7, p2161, 17p

Subject Terms: TUMOR surgery, COMPUTER-assisted surgery, IN vivo studies, INDIUM, INTRAOPERATIVE care, ANIMAL experimentation, CELL receptors, FLUORESCENCE spectroscopy, GASTROINTESTINAL tumors, GENE expression profiling, RESEARCH funding, VISUALIZATION, PEPTIDE hormones, CELL lines, MOLECULAR structure, MICE, PROSTATE tumors, BREAST tumors

In Vivo Efficacy Testing of Peptide Receptor Radionuclide Therapy Radiosensitization Using Olaparib.

Authors: Feijtel, Danny, Reuvers, Thom G. A., van Tuyll-van Serooskerken, Christine, de Ridder, Corrina M. A., Stuurman, Debra C., de Blois, Erik, Verkaik, Nicole S., de Bruijn, Peter, Koolen, Stijn L. W., de Jong, Marion, Nonnekens, Julie

Source: Cancers; Feb2023, Vol. 15 Issue 3, p915, 11p

Subject Terms: DRUG efficacy, COMBINATION drug therapy, ANIMAL experimentation, CELL receptors, RADIOISOTOPES, RADIATION-sensitizing agents, NEUROENDOCRINE tumors, MICE

Patient-Derived Xenografts and Organoids Recapitulate Castration-Resistant Prostate Cancer with Sustained Androgen Receptor Signaling.

Authors: Van Hemelryk, Annelies, Tomljanovic, Ingrid, de Ridder, Corrina M. A., Stuurman, Debra C., Teubel, Wilma J., Erkens-Schulze, Sigrun, Verhoef, Esther I., Remmers, Sebastiaan, Mahes, Amrish J., van Leenders, Geert J. L. H., van Royen, Martin E., van de Werken, Harmen J. G., Grudniewska, Magda, Jenster, Guido W., van Weerden, Wytske M.

Source: Cells (2073-4409); Nov2022, Vol. 11 Issue 22, p3632, 21p

Subject Terms: CASTRATION-resistant prostate cancer, ANDROGEN receptors, XENOGRAFTS, ORGANOIDS, DNA repair

Safety of [¹⁷⁷Lu]Lu-NeoB treatment: a preclinical study characterizing absorbed dose and acute, early, and late organ toxicity.

Authors: Ruigrok, Eline A. M., Verhoeven, Marjolein, Konijnenberg, Mark W., de Blois, Erik, de Ridder, Corrina M. A., Stuurman, Debra C., Bertarione, Luisa, Rolfo, Katia, de Jong, Marion, Dalm, Simone U.

Source: European Journal of Nuclear Medicine & Molecular Imaging; Nov2022, Vol. 49 Issue 13, p4440-4451, 12p, 3 Diagrams, 1 Chart, 4 Graphs

Subject Terms: GASTRIN receptors, RADIATION dosimetry, TOXICITY testing, RADIOLIGAND assay, HISTOLOGY

The Effect of VPA Treatment on Radiolabeled DOTATATE Uptake: Differences Observed In Vitro and In Vivo.

Authors: Klomp, Maria J., Hofland, Leo J., van den Brink, Lilian, van Koetsveld, Peter M., Dogan, Fadime, de Ridder, Corrina M. A., Stuurman, Debra C., Clahsen-van Groningen, Marian C., de Jong, Marion, Dalm, Simone U.

Source: Pharmaceutics; Jan2022, Vol. 14 Issue 1, p173-173, 1p

Subject Terms: PEPTIDE receptors, VALPROIC acid, RENAL circulation, SOMATOSTATIN receptors, NEPHROTOXICOLOGY, TREATMENT effectiveness