Uncovering the Role of N-Glycan Occupancy on the Cooperative Assembly of Spike and Angiotensin Converting Enzyme 2 Complexes: Insights from Glycoengineering and Native Mass Spectrometry

Authors: El-Baba, Tarick J., Lutomski, Corinne A., Burnap, Sean A., Bolla, Jani R., Baker, Lindsay A., Baldwin, Andrew J., Struwe, Weston B., Robinson, Carol V.

Source: Journal of the American Chemical Society. 145(14):8021-8032

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Mass photometry reveals SARS-CoV-2 spike stabilisation to impede ACE2 binding through altered conformational dynamicsElectronic supplementary information (ESI) available. See DOI: https://doi.org/10.1039/d2cc04711j

Authors: Burnap, Sean A., Struwe, Weston B.

Source: Chemical communications. 58(93):12939-12942

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State‐of‐the‐art glycosaminoglycan characterization

Authors: Zappe, Andreas, Miller, Rebecca L., Struwe, Weston B., Pagel, Kevin

Source: Mass spectrometry reviews. 41(6):1040-1071

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Structural and Functional Glycosylation of the Abdala COVID-19 Vaccine.

Authors: Burnap, Sean A, Calvaresi, Valeria, Cabrera, Gleysin, Pousa, Satomy, Limonta, Miladys, Ramos, Yassel, González, Luis Javier, Harvey, David J, Struwe, Weston B

Source: Glycobiology; Mar2025, Vol. 35 Issue 3, p1-12, 12p

Subject Terms: IMMUNE recognition, STRUCTURAL dynamics, COVID-19 vaccines, RECEPTOR antibodies, GLYCOSYLATION, PROTEIN-protein interactions

Defining proteoform-specific interactions for drug targeting in a native cell signalling environment

Authors: Lutomski, Corinne A., Bennett, Jack L., El-Baba, Tarick J., Wu, Di, Hinkle, Joshua D., Burnap, Sean A., Liko, Idlir, Mullen, Christopher, Syka, John E. P., Struwe, Weston B., Robinson, Carol V.

Source: Nature Chemistry; 20250101, Issue: Preprints p1-11, 11p

Mass Photometry of Membrane Proteins

Authors: Olerinyova, Anna, Sonn-Segev, Adar, Gault, Joseph, Eichmann, Cédric, Schimpf, Johannes, Kopf, Adrian H., Rudden, Lucas S.P., Ashkinadze, Dzmitry, Bomba, Radoslaw, Frey, Lukas, Greenwald, Jason, Degiacomi, Matteo T., Steinhilper, Ralf, Killian, J. Antoinette, Friedrich, Thorsten, Riek, Roland, Struwe, Weston B., Kukura, Philipp

Source: In Chem 14 January 2021 7(1):224-236

Hyper-truncated Asn355- and Asn391-glycans modulate the activity of neutrophil granule myeloperoxidase

Authors: Tjondro, Harry C., Ugonotti, Julian, Kawahara, Rebeca, Chatterjee, Sayantani, Loke, Ian, Chen, Siyun, Soltermann, Fabian, Hinneburg, Hannes, Parker, Benjamin L., Venkatakrishnan, Vignesh, Dieckmann, Regis, Grant, Oliver C., Bylund, Johan, Rodger, Alison, Woods, Robert J., Karlsson-Bengtsson, Anna, Struwe, Weston B., Thaysen-Andersen, Morten

Source: In Journal of Biological Chemistry January-June 2021 296

Native Mass Spectrometry Meets Glycomics: Resolving Structural Detail and Occupancy of Glycans on Intact Glycoproteins

Authors: Chen, Siyun, Wu, Di, Robinson, Carol V., Struwe, Weston B.

Source: Analytical chemistry. 93(30):10435-10443

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Label-free methods for optical in vitro characterization of protein–protein interactions

Authors: Soltermann, Fabian, Struwe, Weston B., Kukura, Philipp

Source: Physical chemistry chemical physics. 23(31):16488-16500

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100125865487.0x000001&indx=1&recIds=ETOCvdc_100125865487.0x000001

Atomically resolved imaging of the conformations and adsorption geometries of individual β-cyclodextrins with non-contact AFM.

Authors: Grabarics, Márkó, Mallada, Benjamín, Edalatmanesh, Shayan, Jiménez-Martín, Alejandro, Pykal, Martin, Ondráček, Martin, Kührová, Petra, Struwe, Weston B., Banáš, Pavel, Rauschenbach, Stephan, Jelínek, Pavel, de la Torre, Bruno

Source: Nature Communications; 11/2/2024, Vol. 15 Issue 1, p1-7, 7p

Subject Terms: ATOMIC force microscopy, MOLECULAR structure, GLYCAN structure, MATERIALS science, ULTRAHIGH vacuum

A Bioorthogonal Precision Tool for Human N‑Acetylglucosaminyltransferase V.

Authors: Liu, Yu, Bineva-Todd, Ganka, Meek, Richard W., Mazo, Laura, Piniello, Beatriz, Moroz, Olga, Burnap, Sean A., Begum, Nadima, Ohara, André, Roustan, Chloe, Tomita, Sara, Kjaer, Svend, Polizzi, Karen, Struwe, Weston B., Rovira, Carme, Davies, Gideon J., Schumann, Benjamin

Source: Journal of the American Chemical Society; 10/2/2024, Vol. 146 Issue 39, p26707-26718, 12p

Engineer RNA‐Protein Nanowires as Light‐Responsive Biomaterials

Authors: Younas, Tayyaba, Liu, Chang, Struwe, Weston B., Kukura, Philipp, He, Lizhong

Source: Small. 19(12)

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Relating glycoprotein structural heterogeneity to function – insights from native mass spectrometry

Authors: Struwe, Weston B, Robinson, Carol V

Source: In Current Opinion in Structural Biology October 2019 58:241-248

Correlating Glycoforms of DC‐SIGN with Stability Using a Combination of Enzymatic Digestion and Ion Mobility Mass Spectrometry

Authors: Yen, Hsin‐Yung, Liko, Idlir, Gault, Joseph, Wu, Di, Struwe, Weston B., Robinson, Carol V.

Source: Angewandte Chemie. 132(36):15690-15694

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Quantifying Protein–Protein Interactions by Molecular Counting with Mass Photometry

Authors: Soltermann, Fabian, Foley, Eric D. B., Pagnoni, Veronica, Galpin, Martin, Benesch, Justin L. P., Kukura, Philipp, Struwe, Weston B.

Source: Angewandte Chemie. 132(27):10866-10871

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Ion Mobility-Mass Spectrometry of Glycoconjugates

Authors: Struwe, Weston B., Harvey, David J.

Source: Methods in molecular biology. 2084:203-222

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN622386080&indx=1&recIds=ETOCRN622386080

Lifting the Concentration Limit of Mass Photometry by PEG Nanopatterning.

Authors: Kratochvíl, Jiří, Asor, Roi, Helmi, Seham, Struwe, Weston B., Kukura, Philipp

Source: Nano Letters; 8/21/2024, Vol. 24 Issue 33, p10032-10039, 8p

N-glycan microheterogeneity regulates interactions of plasma proteins

Authors: Wu, Di, Struwe, Weston B., Harvey, David J., Ferguson, Michael A. J., Robinson, Carol V.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2018 Aug . 115(35), 8763-8768.

Access URL: https://www.jstor.org/stable/26530315

Quantitative mass imaging of single biological macromolecules

Authors: Young, Gavin, Hundt, Nikolas, Cole, Daniel, Fineberg, Adam, Andrecka, Joanna, Tyler, Andrew, Olerinyova, Anna, Ansari, Ayla, Marklund, Erik G., Collier, Miranda P., Chandler, Shane A., Tkachenko, Olga, Allen, Joel, Crispin, Max, Billington, Neil, Takagi, Yasuharu, Sellers, James R., Eichmann, Cédric, Selenko, Philipp, Frey, Lukas, Riek, Roland, Galpin, Martin R., Struwe, Weston B., Benesch, Justin L. P., Kukura, Philipp

Source: Science, 2018 Apr . 360(6387), 423-427.

Access URL: https://www.jstor.org/stable/26498859

Separation of Isomeric O-Glycans by Ion Mobility and Liquid Chromatography—Mass Spectrometry

Authors: Jin, Chunsheng, Harvey, David J., Struwe, Weston B., Karlsson, Niclas G.

Source: Analytical chemistry. 91(16):10604-10613

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN621393180&indx=1&recIds=ETOCRN621393180