Serum factors create species-specific barriers to hepatic gene transfer by lipid nanoparticles in liver-humanized mice

Authors: Stone, Daniel ^{1, 4}, Takeuchi, Ryo ^{2, 4}, Dulin, Harrison ^{1, 4}, Loprieno, Michelle A. ^{1, 4}, Strongin, Daniel E. ³, Sathees, Saraswathi ³, Cradick, Thomas J. ², Aubert, Martine ¹, Roychoudhury, Pavitra ^{1, 3}, Gordon, Jennifer ², Jerome, Keith R. ^{1, 3, ∗}

Source: In Molecular Therapy - Methods & Clinical Development April 2025

Viral gene drive spread during herpes simplex virus 1 infection in mice.

Authors: Walter, Marius, Haick, Anoria K., Riley, Rebeccah, Massa, Paola A., Strongin, Daniel E., Klouser, Lindsay M., Loprieno, Michelle A., Stensland, Laurence, Santo, Tracy K., Roychoudhury, Pavitra, Aubert, Martine, Taylor, Matthew P., Jerome, Keith R., Verdin, Eric

Source: Nature Communications; 9/20/2024, Vol. 15 Issue 1, p1-18, 18p

Subject Terms: HUMAN herpesvirus 1, LATENT infection, HOMOLOGOUS recombination, VIRAL genes, PERIPHERAL nervous system, HERPESVIRUS diseases

Molecular Insights into Inhibition of the Methylated Histone-Plant Homeodomain Complexes by Calixarenes

Authors: Ali, Muzaffar, Daze, Kevin D., Strongin, Daniel E., Rothbart, Scott B., Rincon-Arano, Hector, Allen, Hillary F., Li, Janessa, Strahl, Brian D. ^**, Hof, Fraser, Kutateladze, Tatiana G.

Source: In Journal of Biological Chemistry 18 September 2015 290(38):22919-22930

A multiplexed barcode approach to simultaneously evaluate gene delivery by adeno-associated virus capsid variants in nonhuman primates.

Authors: Stone, Daniel, Meumann, Nadja, Kuhlmann, Anne-Sophie, Peterson, Christopher W., Hong Xie, Roychoudhury, Pavitra, Loprieno, Michelle A., Xuan-Khang Vu, Strongin, Daniel E., Kenkel, Elizabeth J., Haick, Anoria, Stensland, Laurence, Obenza, Willimark M., Parrott, Jacob, Nelson, Veronica, Murnane, Robert D., Meei-Li Huang, Aubert, Martine, Kiem, Hans-Peter, Büning, Hildegard

Source: Hepatology Communications; Feb2023, Vol. 7 Issue 2, p1-14, 14p

Subject Terms: ADENO-associated virus, VIRAL tropism, PRIMATES, GENETIC vectors, TRANSGENE expression, RHESUS monkeys, GENE therapy

Red fluorescent proteins with enhanced bacterial expression, increased brightness and reduced aggregation

Monomeric red fluorescent proteins

RED FLUORESCENT PROTEINS WITH ENHANCED BACTERIAL EXPRESSION, INCREASED BRIGHTNESS AND REDUCED AGGREGATION

MONOMERIC RED FLUORESCENT PROTEINS

MONOMERIC RED FLUORESCENT PROTEINS

Monomeric red fluorescent proteins

Chromophore Formation in DsRed Occurs by a Branched Pathway.

Authors: Strack, Rita L., Strongin, Daniel E., Mets, Laurens

Source: Journal of the American Chemical Society; June 23 2010, Vol. 132 Issue 24, p8496-8505, 10p

Sec16 is a Determinant of Transitional ER Organization

Authors: Connerly, Pamela L., Esaki, Masatoshi, Montegna, Elisabeth A., Strongin, Daniel E., Levi, Stephanie, Soderholm, Jon, Glick, Benjamin S. ^*

Source: In Current Biology 23 August 2005 15(16):1439-1447

Nucleolar tethering mediates pairing between the IgH and Myc loci.

Authors: Strongin, Daniel E¹ (AUTHOR), Groudine, Mark^1,2 (AUTHOR), Politz, Joan C Ritland¹ (AUTHOR) jritland@fhcrc.org

Source: Nucleus (1949-1034). Sep/Oct2014, Vol. 5 Issue 5, p474-481. 19p.

Subject Terms: *CHROMOSOMES, *CELL nuclei, *GENES, *B cells, *CHROMOSOMAL translocation, *MYC oncogenes

A noncytotoxic DsRed variant for whole-cell labeling.

Authors: Strack, Rita L.¹, Strongin, Daniel E.², Bhattacharyya, Dibyendu², Wen Tao³, Berman, Allison², Broxmeyer, Hal E.³, Keenan, Robert J.¹, Glick, Benjamin S.² bsglick@uchicago.edu

Source: Nature Methods. Nov2008, Vol. 5 Issue 11, p955-957. 3p. 3 Graphs.

Subject Terms: *PROTEINS, *POLYPEPTIDES, *MOLECULAR chaperones, *BIOMOLECULES, *KININS

Golgi maturation visualized in living yeast.

Authors: Losev, Eugene, Reinke, Catherine A., Jellen, Jennifer, Strongin, Daniel E., Bevis, Brooke J., Glick, Benjamin S.

Source: Nature. 6/22/2006, Vol. 441 Issue 7096, p1002-1006. 5p. 4 Graphs.

Subjects: GOLGI apparatus, YEAST, BIOLOGICAL models, PROTEINS, CARRIER proteins, BIOLOGICAL transport

A noncytotoxic DsRed variant for whole-cell labeling.

Authors: Strack, Rita L., Strongin, Daniel E., Bhattacharyya, Dibyendu, Tao, Wen, Berman, Allison, Broxmeyer, Hal E., Keenan, Robert J., Glick, Benjamin S.

Source: Proceedings of SPIE; Nov2009, Issue 1, p719109-719109-12, 12p

Identification of phospholipase A2 and phospholipase C activities in calcium regulatory endomembranes of sand dollar cells.

Authors: Silver, Robert B., Strongin, Daniel E., Hurwitz, Layne R.

Source: Biological Bulletin; October 1997, Vol. 193, p236-237, 2p

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Nucleolar tethering mediates pairing between the IgHand Mycloci

Authors: Strongin, Daniel E, Groudine, Mark, Politz, Joan C Ritland

Source: Nucleus; September 2014, Vol. 5 Issue: 5 p474-481, 8p

Gene editing and elimination of latent herpes simplex virus in vivo.

Authors: Aubert, Martine, Strongin, Daniel E., Roychoudhury, Pavitra, Loprieno, Michelle A., Haick, Anoria K., Klouser, Lindsay M., Stensland, Laurence, Huang, Meei-Li, Makhsous, Negar, Tait, Alexander, De Silva Feelixge, Harshana S., Galetto, Roman, Duchateau, Philippe, Greninger, Alexander L., Stone, Daniel, Jerome, Keith R.

Source: Nature Communications; 8/18/2020, Vol. 11 Issue 1, pN.PAG-N.PAG, 1p

Subject Terms: HERPES simplex virus, GENE therapy, GENOME editing, RNA sequencing, ADENO-associated virus