DNAJB1-PRKACA fusion neoantigens elicit rare endogenous T cell responses that potentiate cell therapy for fibrolamellar carcinoma

Authors: Kirk, Allison M., Crawford, Jeremy Chase, Chou, Ching-Heng, Guy, Cliff, Pandey, Kirti, Kozlik, Tanya, Shah, Ravi K., Chung, Shanzou, Nguyen, Phuong, Zhang, Xiaoyu, Wang, Jin, Bell, Matthew, Mettelman, Robert C., Allen, E. Kaitlynn, Pogorelyy, Mikhail V., Kim, Hyunjin, Minervina, Anastasia A., Awad, Walid, Bajracharya, Resha, White, Toni, Long, Donald, Jr., Gordon, Brittney, Morrison, Michelle, Glazer, Evan S., Murphy, Andrew J., Jiang, Yixing, Fitzpatrick, Elizabeth A., Yarchoan, Mark, Sethupathy, Praveen, Croft, Nathan P., Purcell, Anthony W., Federico, Sara M., Stewart, Elizabeth, Gottschalk, Stephen, Zamora, Anthony E., DeRenzo, Christopher, Strome, Scott E., Thomas, Paul G.

Source: In Cell Reports Medicine 19 March 2024 5(3)

NK cell expression of Tim-3: First impressions matter

Authors: So, Edward C., Khaladj-Ghom, Ariana, Ji, Yaping, Amin, Julian, Song, Yang, Burch, Erin, Zhou, Hua, Sun, Haoping, Chen, Shaodong, Bentzen, Soren, Hertzano, Ronna, Zhang, Xiaoyu, Strome, Scott E.

Source: In Immunobiology May 2019 224(3):362-370

Intratumor genetic heterogeneity in squamous cell carcinoma of the oral cavity

Authors: Zandberg, Dan P., Tallon, Luke J., Nagaraj, Sushma, Sadzewicz, Lisa K., Zhang, Yuji, Strome, Maxwell B., Zhao, Xuechu E., Vavikolanu, Kranthi, Zhang, Xiaoyu, Papadimitriou, John C., Hubbard, Fleesie A., Bentzen, Søren M., Strome, Scott E., Fraser, Claire M.

Source: Head & neck. 41(8):2514-2524

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100085058530.0x000001&indx=1&recIds=ETOCvdc_100085058530.0x000001

Costimulatory B7-H1 in Renal Cell Carcinoma Patients: Indicator of Tumor Aggressiveness and Potential Therapeutic Target

Authors: Thompson, R. Houston, Gillett, Michael D., Cheville, John C., Lohse, Christine M., Dong, Haidong, Webster, W. Scott, Krejci, Kent G., Lobo, John R., Sengupta, Shomik, Chen, Lieping, Zincke, Horst, Blute, Michael L., Strome, Scott E., Leibovich, Bradley C., Kwon, Eugene D., Allison, James P.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2004 Dec 01. 101(49), 17174-17179.

Access URL: https://www.jstor.org/stable/3373979

Recombinant human IgG1 based Fc multimers, with limited FcR binding capacity, can effectively inhibit complement-mediated disease

Authors: Sun, Haoping, Olsen, Henrik S., Mérigeon, Emmanuel Y., So, Edward, Burch, Erin, Kinsey, Susan, Papadimitriou, John C., Drachenberg, Cinthia B., Bentzen, Søren M., Block, David S., Strome, Scott E., Zhang, Xiaoyu

Source: In Journal of Autoimmunity November 2017 84:97-108

A fully recombinant human IgG1 Fc multimer (GL-2045) inhibits complement-mediated cytotoxicity and induces iC3b

Authors: Zhou, Hua, Olsen, Henrik, So, Edward, Mérigeon, Emmanuel, Rybin, Denis, Owens, Jane, LaRosa, Gregory, Block, David S., Strome, Scott E., Zhang, Xiaoyu

Source: In Blood Advances 14 March 2017 1(8):504-515

The role of antagonists of the PD-1:PD-L1/PD-L2 axis in head and neck cancer treatment

Authors: Pai, Sara I., Zandberg, Dan P., Strome, Scott E.

Source: In Oral Oncology October 2016 61:152-158

Impact of Detachment Methods on M2 Macrophage Phenotype and Function

Authors: Chen, Shaodong, So, Edward C., Strome, Scott E., Zhang, Xiaoyu

Source: In Journal of Immunological Methods November 2015 426:56-61

Invariant natural killer T cells generated from human adult hematopoietic stem-progenitor cells are poly-functional

Authors: Sun, Wenji, Wang, Yi, East, James E., Kimball, Amy S., Tkaczuk, Katherine, Kesmodel, Susan, Strome, Scott E., Webb, Tonya J.

Source: In Cytokine March 2015 72(1):48-57

Fc fusion as a platform technology: potential for modulating immunogenicity

Authors: Levin, Ditza, Golding, Basil, Strome, Scott E., Sauna, Zuben E.

Source: In Trends in Biotechnology January 2015 33(1):27-34

Is routine genetic testing warranted in head and neck paragangliomas?

Authors: Gupta, Nidhi, Strome, Scott E., Hatten, Kyle M.

Source: Laryngoscope. 129(7):1491-1493

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100083109826.0x000001&indx=1&recIds=ETOCvdc_100083109826.0x000001

The role of the PD-L1:PD-1 pathway in squamous cell carcinoma of the head and neck

Authors: Zandberg, Dan P., Strome, Scott E.

Source: In Oral Oncology July 2014 50(7):627-632

Anti-CD20 Antibody with Multimerized Fc Domains: A Novel Strategy To Deplete B Cells and Augment Treatment of Autoimmune Disease

Authors: Zhang, Xiaoyu, Olsen, Henrik S., Chen, Shaodong, So, Edward, Zhou, Hua, Burch, Erin, Mérigeon, Emmanuel Y., Block, David S., Strome, Scott E.

Source: Journal of immunology. 196(3):1165-1176

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN604659885&indx=1&recIds=ETOCRN604659885

Tumour antigen targeted monoclonal antibodies incorporating a novel multimerisation domain significantly enhance antibody dependent cellular cytotoxicity against colon cancer

Authors: Jain, Ajay, Poonia, Bhawna, So, Edward C., Vyzasatya, Ravi, Burch, Erin E., Olsen, Henrik S., Mérigeon, Emmanuel Y., Block, David S., Zhang, Xiaoyu, Schulze, Dan H., Hanna, Nader N., Twadell, William S., Yfantis, Harris G., Chan, Siaw L., Cai, Ling, Strome, Scott E.

Source: In European Journal of Cancer October 2013 49(15):3344-3352

A high throughput method for enrichment of natural killer cells and lymphocytes and assessment of in vitro cytotoxicity

Authors: So, Edward C., Sallin, Michelle A., Zhang, Xiaoyu, Chan, Siaw L., Sahni, Lepakshi, Schulze, Dan H., Davila, Eduardo, Strome, Scott E., Jain, Ajay

Source: In Journal of Immunological Methods 30 August 2013 394(1-2):40-48

Fc multimers effectively treat murine models of multiple sclerosis.

Authors: Jin Wang, Brown, Kellie, Danehy, Caroline, Mérigeon, Emmanuel, Goralski, Stephen, Rice, Samuel, Torgbe, Kwame, Thomas, Fridtjof, Block, David, Olsen, Henrik, Strome, Scott E., Fitzpatrick, Elizabeth A.

Source: Frontiers in Immunology; 2023, p1-20, 20p

Subject Terms: MULTIPLE sclerosis, T helper cells, T cells, CELL migration, SPINAL cord

Complement component C1q is an immunological rheostat that regulates Fc:FcγR interactions.

Authors: So, Edward C., Zhou, Hua, Greenwell, Ariana, Burch, Erin E., Ji, Yaping, Mérigeon, Emmanuel Y., Olsen, Henrik S., Bentzen, Søren M., Block, David S., Zhang, Xiaoyu, Strome, Scott E.

Source: Immunogenetics; Aug2023, Vol. 75 Issue 4, p369-383, 15p

Subject Terms: FC receptors, ANTIBODY-dependent cell cytotoxicity, HOMEOSTASIS, KILLER cells, IMMUNE complexes, IMMUNOGLOBULIN G, BINDING sites

Bone marrow vaccination: A novel approach to enhance antigen specific antitumor immunity

Authors: Fresnay, Stephanie, Zhang, Xiaoyu, Strome, Scott E., Sewell, Duane A.

Source: In Vaccine 3 November 2011 29(47):8599-8605

Human γδ T lymphocytes induce robust NK cell–mediated antitumor cytotoxicity through CD137 engagement

Authors: Maniar, Amudhan, Zhang, Xiaoyu, Lin, Wei, Gastman, Brian R., Pauza, C. David, Strome, Scott E., Chapoval, Andrei I. ^*

Source: In Blood 9 September 2010 116(10):1726-1733

B7-H1/CD80 interaction is required for the induction and maintenance of peripheral T-cell tolerance

Authors: Park, Jang-June ^*, Omiya, Ryusuke ^*, Matsumura, Yumiko ^*, Sakoda, Yukimi, Kuramasu, Atsuo, Augustine, Mathew M., Yao, Sheng, Tsushima, Fumihiko, Narazaki, Hidehiko, Anand, Sudarshan, Liu, Yingjia, Strome, Scott E., Chen, Lieping, Tamada, Koji ^*

Source: In Blood 26 August 2010 116(8):1291-1298