Can we do better with Mylotarg? Model-based assessment of opportunities to improve therapeutic index

Authors: Stoddard, Madison, Yuan, Lin, Cooper, Jodi, Carcillo Neumar, Christine, Hibner, Barbara, Gardner, Humphrey, Chakravarty, Arijit

Source: In Toxicology and Applied Pharmacology September 2024 490

Looking under the lamp-post: quantifying the performance of contact tracing in the United States during the SARS-CoV-2 pandemic.

Authors: Bayly, Henry¹ (AUTHOR), Stoddard, Madison² (AUTHOR), Van Egeren, Debra³ (AUTHOR), Murray, Eleanor J⁴ (AUTHOR), Raifman, Julia⁵ (AUTHOR), Chakravarty, Arijit² (AUTHOR), White, Laura F¹ (AUTHOR) lfwhite@bu.edu

Source: BMC Public Health. 2/23/2024, Vol. 24 Issue 1, p1-11. 11p.

Subject Terms: *CONTACT tracing, *COVID-19 pandemic, *DIAGNOSTIC use of polymerase chain reaction, *ANTIGEN analysis, *DISEASE outbreaks

Geographic Terms: UNITED States, EAST Asia

Rapid relaxation of pandemic restrictions after vaccine rollout favors growth of SARS-CoV-2 variants: A model-based analysis.

Authors: Van Egeren, Debra^1,2,3 (AUTHOR), Stoddard, Madison⁴ (AUTHOR), Novokhodko, Alexander⁵ (AUTHOR), Rogers, Michael S.⁶ (AUTHOR), Joseph-McCarthy, Diane⁷ (AUTHOR), Zetter, Bruce⁶ (AUTHOR), Chakravarty, Arijit⁴ (AUTHOR) arijit@fractaltx.com

Source: PLoS ONE. 11/24/2021, Vol. 16 Issue 11, p1-14. 14p.

Subject Terms: *SARS-CoV-2, *VACCINE effectiveness, *COVID-19, *NATURAL immunity, *VACCINES

Geographic Terms: UNITED States

Computational identification of antibody-binding epitopes from mimotope datasets.

Authors: Rang Li, Wilderotter, Sabrina, Stoddard, Madison, Van Egeren, Debra, Chakravarty, Arijit, Joseph-McCarthy, Diane

Source: Frontiers in Bioinformatics; 2024, p1-14, 14p

Beyond the new normal: Assessing the feasibility of vaccine-based suppression of SARS-CoV-2.

Authors: Stoddard, Madison¹ (AUTHOR) madison.stoddard@fractaltx.com, Sarkar, Sharanya² (AUTHOR), Yuan, Lin¹ (AUTHOR), Nolan, Ryan P.³ (AUTHOR), White, Douglas E.⁴ (AUTHOR), White, Laura F.⁵ (AUTHOR), Hochberg, Natasha S.^6,7,8 (AUTHOR), Chakravarty, Arijit¹ (AUTHOR)

Source: PLoS ONE. 7/16/2021, Vol. 16 Issue 7, p1-18. 18p.

Subject Terms: *SARS-CoV-2, *PANDEMICS, *COVID-19 pandemic, *COVID-19, *VIRAL transmission, *VACCINE effectiveness, *EPIDEMIOLOGICAL models

Individually optimal choices can be collectively disastrous in COVID-19 disease control.

Authors: Stoddard, Madison¹, Van Egeren, Debra^2,3,4, Johnson, Kaitlyn E.⁵, Rao, Smriti⁶, Furgeson, Josh⁷, White, Douglas E.⁸, Nolan, Ryan P.⁹, Hochberg, Natasha^10,11,12, Chakravarty, Arijit¹ arijit@fractaltx.com

Source: BMC Public Health. 4/30/2021, Vol. 21 Issue 1, p1-12. 12p. 2 Charts, 6 Graphs.

Subject Terms: *COVID-19, *SARS-CoV-2, *VACCINE refusal, *GAME theory, *COMMUNICABLE diseases

In the long shadow of our best intentions: Model-based assessment of the consequences of school reopening during the COVID-19 pandemic.

Authors: Johnson, Kaitlyn E.^1,2 (AUTHOR) k.john@utexas.edu, Stoddard, Madison² (AUTHOR), Nolan, Ryan P.³ (AUTHOR), White, Douglas E.⁴ (AUTHOR), Hochberg, Natasha S.^5,6 (AUTHOR), Chakravarty, Arijit² (AUTHOR) k.john@utexas.edu

Source: PLoS ONE. 3/25/2021, Vol. 16 Issue 3, p1-17. 17p.

Subject Terms: *COVID-19 pandemic, *COVID-19, *DISEASE clusters, *PANDEMICS, *CONTACT tracing, *DISEASE prevalence, *VIRTUAL communities, *COMMUNITY-school relationships

Geographic Terms: UNITED States

Ketogenic diet prevents neuronal firing increase within the substantia nigra during pentylenetetrazole-induced seizure in rats

Authors: Viggiano, Andrea, Stoddard, Madison, Pisano, Simone, Operto, Francesca Felicia, Iovane, Valentina, Monda, Marcellino, Coppola, Giangennaro

Source: Brain research bulletin. 125:168-172

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100060256850.0x000001&indx=1&recIds=ETOCvdc_100060256850.0x000001

Antibody escape, the risk of serotype formation, and rapid immune waning: Modeling the implications of SARS-CoV-2 immune evasion.

Authors: Albright, Catherine, Van Egeren, Debra, Thakur, Aditya, Chakravarty, Arijit, White, Laura F., Stoddard, Madison

Source: PLoS ONE; 10/18/2023, Vol. 18 Issue 10, p1-17, 17p

Subject Terms: SARS-CoV-2, IMMUNOGLOBULINS, HERD immunity, INFECTIOUS disease transmission, MONOCLONAL antibodies, COVID-19 pandemic, ENDEMIC diseases

Vaccines Alone Cannot Slow the Evolution of SARS-CoV-2.

Authors: Van Egeren, Debra, Stoddard, Madison, White, Laura F., Hochberg, Natasha S., Rogers, Michael S., Zetter, Bruce, Joseph-McCarthy, Diane, Chakravarty, Arijit

Source: Vaccines; Apr2023, Vol. 11 Issue 4, p853, 14p

Subject Terms: SARS-CoV-2, COVID-19, VIRAL transmission, VIRAL mutation, COVID-19 pandemic

Heterogeneity in Vaccinal Immunity to SARS-CoV-2 Can Be Addressed by a Personalized Booster Strategy.

Authors: Stoddard, Madison, Yuan, Lin, Sarkar, Sharanya, Mangalaganesh, Shruthi, Nolan, Ryan P., Bottino, Dean, Hather, Greg, Hochberg, Natasha S., White, Laura F., Chakravarty, Arijit

Source: Vaccines; Apr2023, Vol. 11 Issue 4, p806, 14p

Subject Terms: SARS-CoV-2, BOOSTER vaccines, HETEROGENEITY, BINDING site assay, IMMUNITY

Endemicity Is Not a Victory: The Unmitigated Downside Risks of Widespread SARS-CoV-2 Transmission.

Authors: Stoddard, Madison¹, Novokhodko, Alexander², Sarkar, Sharanya³, Van Egeren, Debra⁴, White, Laura F.⁵, Hochberg, Natasha S.⁶, Rogers, Michael S.^7,8, Zetter, Bruce^7,8, Joseph-McCarthy, Diane⁹, Chakravarty, Arijit¹ arijit@fractaltx.com

Source: COVID. Dec2022, Vol. 2 Issue 12, p1689-1709. 21p.

Subject Terms: *SARS-CoV-2, *COVID-19 vaccines, *MICROBIAL virulence, *EPIDEMIOLOGY, *INFECTIOUS disease transmission

Controlling long-term SARS-CoV-2 infections can slow viral evolution and reduce the risk of treatment failure.

Authors: Van Egeren, Debra, Novokhodko, Alexander, Stoddard, Madison, Tran, Uyen, Zetter, Bruce, Rogers, Michael S., Joseph-McCarthy, Diane, Chakravarty, Arijit

Source: Scientific Reports; 11/19/2021, Vol. 11 Issue 1, p1-9, 9p

Subject Terms: TREATMENT failure, SARS-CoV-2, CONVALESCENT plasma, COVID-19, HERD immunity, VIRUS diseases

Using mixed-effects modeling to estimate decay kinetics of response to SARS-CoV-2 infection.

Authors: Bottino, Dean, Hather, Greg, Yuan, L, Stoddard, Madison, White, Lin, Chakravarty, Arijit

Source: Antibody Therapeutics; Jul2021, Vol. 4 Issue 3, p144-148, 5p

Risk of rapid evolutionary escape from biomedical interventions targeting SARS-CoV-2 spike protein.

Authors: Van Egeren, Debra, Novokhodko, Alexander, Stoddard, Madison, Tran, Uyen, Zetter, Bruce, Rogers, Michael, Pentelute, Bradley L., Carlson, Jonathan M., Hixon, Mark, Joseph-McCarthy, Diane, Chakravarty, Arijit

Source: PLoS ONE; 4/28/2021, Vol. 16 Issue 4, p1-17, 17p

Subject Terms: SARS-CoV-2, NATURAL immunity, COVID-19, PROTEIN domains, HERD immunity

This result is not displayed to guests.
Login for full access.

This result is not displayed to guests.
Login for full access.

This result is not displayed to guests.
Login for full access.