Serine metabolism remodeling after platinum-based chemotherapy identifies vulnerabilities in a subgroup of resistant ovarian cancers

Authors: Tom Van Nyen, Mélanie Planque, Lilian van Wagensveld, Joao A. G. Duarte, Esther A. Zaal, Ali Talebi, Matteo Rossi, Pierre-René Körner, Lara Rizzotto, Stijn Moens, Wout De Wispelaere, Regina E. M. Baiden-Amissah, Gabe S. Sonke, Hugo M. Horlings, Guy Eelen, Emanuele Berardi, Johannes V. Swinnen, Celia R. Berkers, Peter Carmeliet, Diether Lambrechts, Ben Davidson, Reuven Agami, Sarah-Maria Fendt, Daniela Annibali, Frédéric Amant

Source: Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/ea6155ed60d848d191feda4d57429fb3

The mitotic checkpoint is a targetable vulnerability of carboplatin-resistant triple negative breast cancers

Authors: Stijn Moens, Peihua Zhao, Maria Francesca Baietti, Oliviero Marinelli, Delphi Van Haver, Francis Impens, Giuseppe Floris, Elisabetta Marangoni, Patrick Neven, Daniela Annibali, Anna A. Sablina, Frédéric Amant

Source: Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/23a5f34fef334ff789f85c69f707a9be

Wnt/β-Catenin Inhibition Disrupts Carboplatin Resistance in Isogenic Models of Triple-Negative Breast Cancer

Authors: Willy Antoni Abreu de Oliveira, Stijn Moens, Youssef El Laithy, Bernard K. van der Veer, Paraskevi Athanasouli, Emanuela Elsa Cortesi, Maria Francesca Baietti, Kian Peng Koh, Juan-Jose Ventura, Frédéric Amant, Daniela Annibali, Frederic Lluis

Source: Frontiers in Oncology, Vol 11 (2021)

Subject Terms: triple negative breast cancer, WNT pathway, platinum-resistance, cancer stem cells, patient-derived xenograft models, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2021.705384/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/5758a8c5ff9c45e9821c7540ea658c47

The Cancer Cell Oxygen Sensor PHD2 Promotes Metastasis via Activation of Cancer-Associated Fibroblasts

Authors: Anna Kuchnio, Stijn Moens, Ulrike Bruning, Karol Kuchnio, Bert Cruys, Bernard Thienpont, Michaël Broux, Andreea Alexandra Ungureanu, Rodrigo Leite de Oliveira, Françoise Bruyère, Henar Cuervo, Ann Manderveld, An Carton, Juan Ramon Hernandez-Fernaud, Sara Zanivan, Carmen Bartic, Jean-Michel Foidart, Agnes Noel, Stefan Vinckier, Diether Lambrechts, Mieke Dewerchin, Massimiliano Mazzone, Peter Carmeliet

Source: Cell Reports, Vol 12, Iss 6, Pp 992-1005 (2015)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124715007500; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/84a2f84782c44a938ff33527b7a39ea2