Brain development during the lifespan of cynomolgus monkeys

Authors: Zhiqiang Tan, Binbin Nie, Huanhua Wu, Bang Li, Jingjie Shang, Tianhao Zhang, Zeyu Xiao, Chenchen Dong, Chunyuan Zeng, Biao Wu, Lu Hou, Bin Guo, Yong Cheng, Jian Gong, Weijian Ye, Lin Xu, Yuefeng Li, Xiaojiang Li, Steven H. Liang, Baoci Shan, Hao Xu, Lu Wang

Source: NeuroImage, Vol 305, Iss , Pp 120952- (2025)

Subject Terms: Brain development, Cynomolgus monkey, [18F]FDG PET-MRI, Volume, Glucose metabolism, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S105381192400449X; https://doaj.org/toc/1095-9572

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Discovery and evaluation of a novel 18F-labeled vasopressin 1a receptor PET ligand with peripheral binding specificity

Authors: Junqi Hu, Yinlong Li, Chenchen Dong, Huiyi Wei, Kai Liao, Junjie Wei, Chunyu Zhao, Ahmad Chaudhary, Jiahui Chen, Hao Xu, Ke Zhong, Steven H. Liang, Lu Wang, Weijian Ye

Source: Acta Pharmaceutica Sinica B, Vol 14, Iss 9, Pp 4014-4027 (2024)

Subject Terms: Vasopressin, Autism, V1a receptor, Positron emission tomography, PET imaging, Radiolabeling, Therapeutics. Pharmacology, RM1-950

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Relation: http://www.sciencedirect.com/science/article/pii/S2211383524002296; https://doaj.org/toc/2211-3835

Access URL: https://doaj.org/article/3d89230ad29d4937a8d0aff7aaaff0fb

Retraction Note: Target receptor identification and subsequent treatment of resected brain tumors with encapsulated and engineered allogeneic stem cells

Authors: Deepak Bhere, Sung Hugh Choi, Pim van de Donk, David Hope, Kiki Gortzak, Amina Kunnummal, Jasneet Khalsa, Esther Revai Lechtich, Clemens Reinshagen, Victoria Leon, Nabil Nissar, Wenya Linda Bi, Cheng Feng, Hongbin Li, Yu Shrike Zhang, Steven H. Liang, Neil Vasdev, Walid Ibn Essayed, Pablo Valdes Quevedo, Alexandra Golby, Naima Banouni, Anna Palagina, Reza Abdi, Brian Fury, Stelios Smirnakis, Alarice Lowe, Brock Reeve, Arthur Hiller, E. Antonio Chiocca, Glenn Prestwich, Hiroaki Wakimoto, Gerhard Bauer, Khalid Shah

Source: Nature Communications, Vol 16, Iss 1, Pp 1-2 (2025)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/378e669e61234d189abc09026cf7e809

Preliminary Exploration of Pseudo-CT-Based Attenuation Correction for Simultaneous PET/MRI Brain Imaging in Nonhuman Primates

Authors: Chi-Hyeon Yoo, Jonathan M. DuBois, Lu Wang, Yongjin Tang, Lu Hou, Hao Xu, Jiahui Chen, Steven H. Liang, David Izquierdo-Garcia, Hsiao-Ying Wey

Source: ACS Omega, Vol 8, Iss 48, Pp 45438-45446 (2023)

Subject Terms: Chemistry, QD1-999

File Description: electronic resource

Relation: https://doaj.org/toc/2470-1343

Access URL: https://doaj.org/article/9fd9b79b2f134cf0bffbecea2af9e8ec

Radiochemistry for positron emission tomography

Authors: Jian Rong, Achi Haider, Troels E. Jeppesen, Lee Josephson, Steven H. Liang

Source: Nature Communications, Vol 14, Iss 1, Pp 1-23 (2023)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/fd0ebc3222f8447caabbefd5963ae7f7

Translational molecular imaging and drug development in Parkinson’s disease

Authors: Achi Haider, Nehal H. Elghazawy, Alyaa Dawoud, Catherine Gebhard, Thomas Wichmann, Wolfgang Sippl, Marius Hoener, Ernest Arenas, Steven H. Liang

Source: Molecular Neurodegeneration, Vol 18, Iss 1, Pp 1-21 (2023)

Subject Terms: Translational molecular imaging, Parkinson’s disease, Drug development, Dopamine, α-Synuclein, Mitochondrial dysfunction, Neurology. Diseases of the nervous system, RC346-429, Geriatrics, RC952-954.6

File Description: electronic resource

Relation: https://doaj.org/toc/1750-1326

Access URL: https://doaj.org/article/59f3101b85034b88857c2dd7386d4e92

Structure–activity relationship of pyrazol-4-yl-pyridine derivatives and identification of a radiofluorinated probe for imaging the muscarinic acetylcholine receptor M4

Authors: Ahmed Haider, Xiaoyun Deng, Olivia Mastromihalis, Stefanie K. Pfister, Troels E. Jeppesen, Zhiwei Xiao, Vi Pham, Shaofa Sun, Jian Rong, Chunyu Zhao, Jiahui Chen, Yinlong Li, Theresa R. Connors, April T. Davenport, James B. Daunais, Vahid Hosseini, Wenqing Ran, Arthur Christopoulos, Lu Wang, Celine Valant, Steven H. Liang

Source: Acta Pharmaceutica Sinica B, Vol 13, Iss 1, Pp 213-226 (2023)

Subject Terms: Muscarinic acetylcholine receptor, Positron emission tomography, Neuroimaging, Neuropharmacology, Neurological disorders, Therapeutics. Pharmacology, RM1-950

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Relation: http://www.sciencedirect.com/science/article/pii/S2211383522003203; https://doaj.org/toc/2211-3835

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Visualizing reactive astrocytes: Positron emission tomography imaging ligands for imidazoline‐2 binding sites

Authors: Wanqing Li, Yuqing Qiao, Jiahui Chen, Yinlong Li, Xiaoyu Du, Steven H. Liang, Hualong Fu

Source: View, Vol 4, Iss 6, Pp n/a-n/a (2023)

Subject Terms: imidazoline‐2 binding sites, positron emission tomography (PET) ligand, reactive astrocytes, noninvasive imaging, Biotechnology, TP248.13-248.65, Medical technology, R855-855.5

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Relation: https://doaj.org/toc/2688-3988; https://doaj.org/toc/2688-268X

Access URL: https://doaj.org/article/c361dba5ac914c61978dd9ea8376249c

RETRACTED ARTICLE: Target receptor identification and subsequent treatment of resected brain tumors with encapsulated and engineered allogeneic stem cells

Authors: Deepak Bhere, Sung Hugh Choi, Pim van de Donk, David Hope, Kiki Gortzak, Amina Kunnummal, Jasneet Khalsa, Esther Revai Lechtich, Clemens Reinshagen, Victoria Leon, Nabil Nissar, Wenya Linda Bi, Cheng Feng, Hongbin Li, Yu Shrike Zhang, Steven H. Liang, Neil Vasdev, Walid Ibn Essayed, Pablo Valdes Quevedo, Alexandra Golby, Naima Banouni, Anna Palagina, Reza Abdi, Brian Fury, Stelios Smirnakis, Alarice Lowe, Brock Reeve, Arthur Hiller, E. Antonio Chiocca, Glenn Prestwich, Hiroaki Wakimoto, Gerhard Bauer, Khalid Shah

Source: Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/c3728edd112e43e6baeb95ff129c6000

Discovery of a highly specific 18F-labeled PET ligand for phosphodiesterase 10A enabled by novel spirocyclic iodonium ylide radiofluorination

Authors: Zhiwei Xiao, Huiyi Wei, Yi Xu, Ahmed Haider, Junjie Wei, Shiyu Yuan, Jian Rong, Chunyu Zhao, Guocong Li, Weibin Zhang, Huangcan Chen, Yuefeng Li, Lingling Zhang, Jiyun Sun, Shaojuan Zhang, Hai-Bin Luo, Sen Yan, Qijun Cai, Lu Hou, Chao Che, Steven H. Liang, Lu Wang

Source: Acta Pharmaceutica Sinica B, Vol 12, Iss 4, Pp 1963-1975 (2022)

Subject Terms: Phosphodiesterase 10A, PET radioligand, 18F, Spirocyclic iodonium ylide, Nonhuman primate, Target occupancy, Therapeutics. Pharmacology, RM1-950

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Relation: http://www.sciencedirect.com/science/article/pii/S2211383521004470; https://doaj.org/toc/2211-3835

Access URL: https://doaj.org/article/dbe615a754e04340924e1a3797b18488

[18F]MAGL-4-11 positron emission tomography molecular imaging of monoacylglycerol lipase changes in preclinical liver fibrosis models

Authors: Tuo Shao, Zhen Chen, Jian Rong, Vasily Belov, Jiahui Chen, Andre Jeyarajan, Xiaoyun Deng, Hualong Fu, Qingzhen Yu, Steve H. Rwema, Wenyu Lin, Mikhail Papisov, Lee Josephson, Raymond T. Chung, Steven H. Liang

Source: Acta Pharmaceutica Sinica B, Vol 12, Iss 1, Pp 308-315 (2022)

Subject Terms: [18F]MAGL-4-11, PET imaging, Liver fibrosis, MAGL, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211383521002562; https://doaj.org/toc/2211-3835

Access URL: https://doaj.org/article/8eeb1fa8620445a3995e56ae5f3595fe

Quantitative assessment of translocator protein (TSPO) in the non-human primate brain and clinical translation of [18F]LW223 as a TSPO-targeted PET radioligand

Authors: Zhiqiang Tan, Ahmed Haider, Shaojuan Zhang, Jiahui Chen, Junjie Wei, Kai Liao, Guocong Li, Huiyi Wei, Chenchen Dong, Wenqing Ran, Ying Li, Yuefeng Li, Jian Rong, Yinlong Li, Steven H. Liang, Hao Xu, Lu Wang

Source: Pharmacological Research, Vol 189, Iss , Pp 106681- (2023)

Subject Terms: Neuroinflammation, Translocator protein 18 kDa (TSPO), Positron emission tomography (PET), Kinetic modeling, Translational molecular imaging, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1043661823000373; https://doaj.org/toc/1096-1186

Access URL: https://doaj.org/article/704b743781334525b6bd20a98ba0e61c

Development of a highly-specific 18F-labeled irreversible positron emission tomography tracer for monoacylglycerol lipase mapping

Authors: Zhen Chen, Wakana Mori, Jian Rong, Michael A. Schafroth, Tuo Shao, Richard S. Van, Daisuke Ogasawara, Tomoteru Yamasaki, Atsuto Hiraishi, Akiko Hatori, Jiahui Chen, Yiding Zhang, Kuan Hu, Masayuki Fujinaga, Jiyun Sun, Qingzhen Yu, Thomas L. Collier, Yihan Shao, Benjamin F. Cravatt, Lee Josephson, Ming-Rong Zhang, Steven H. Liang

Source: Acta Pharmaceutica Sinica B, Vol 11, Iss 6, Pp 1686-1695 (2021)

Subject Terms: Monoacylglycerol lipase (MAGL), Central nervous system (CNS), 2-Arachidonylglycerol (2-AG), Arachidonic acid (AA), Positron emission tomography (PET), Fluorine-18, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211383521000381; https://doaj.org/toc/2211-3835

Access URL: https://doaj.org/article/6647b3af1e7f460aab63220f173d99be

Recent developments on PET radiotracers for TSPO and their applications in neuroimaging

Authors: Lingling Zhang, Kuan Hu, Tuo Shao, Lu Hou, Shaojuan Zhang, Weijian Ye, Lee Josephson, Jeffrey H. Meyer, Ming-Rong Zhang, Neil Vasdev, Jinghao Wang, Hao Xu, Lu Wang, Steven H. Liang

Source: Acta Pharmaceutica Sinica B, Vol 11, Iss 2, Pp 373-393 (2021)

Subject Terms: TSPO, Microglial activation, Neuroinflammation, Positron emission tomography (PET), CNS disorders, Therapeutics. Pharmacology, RM1-950

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Relation: http://www.sciencedirect.com/science/article/pii/S2211383520306894; https://doaj.org/toc/2211-3835

Access URL: https://doaj.org/article/f41bf533ef0c495f89c741de8840c7ea

Marriage of black phosphorus and Cu2+ as effective photothermal agents for PET-guided combination cancer therapy

Authors: Kuan Hu, Lin Xie, Yiding Zhang, Masayuki Hanyu, Zhimin Yang, Kotaro Nagatsu, Hisashi Suzuki, Jiang Ouyang, Xiaoyuan Ji, Junjie Wei, Hao Xu, Omid C. Farokhzad, Steven H. Liang, Lu Wang, Wei Tao, Ming-Rong Zhang

Source: Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/ef8f904249e64bcdb1e38f5a9602df07

Evaluation of [18F]Favipiravir in Rodents and Nonhuman Primates (NHP) with Positron Emission Tomography

Authors: Jian Rong, Chunyu Zhao, Xiaotian Xia, Guocong Li, Ahmed Haider, Huiyi Wei, Jiahui Chen, Zhiwei Xiao, Yinlong Li, Xin Zhou, Hao Xu, Thomas L. Collier, Lu Wang, Steven H. Liang

Source: Pharmaceuticals, Vol 16, Iss 4, p 524 (2023)

Subject Terms: favipiravir, COVID-19, SARS-CoV-2, PET, F-18, Medicine, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1424-8247/16/4/524; https://doaj.org/toc/1424-8247

Access URL: https://doaj.org/article/1b2f235d7a9d46f1ab22c19080e08b3e

Development and Validation of [3H]OF-NB1 for Preclinical Assessment of GluN1/2B Candidate Drugs

Authors: Hazem Ahmed, Livio Gisler, Nehal H. Elghazawy, Claudia Keller, Wolfgang Sippl, Steven H. Liang, Ahmed Haider, Simon M. Ametamey

Source: Pharmaceuticals, Vol 15, Iss 8, p 960 (2022)

Subject Terms: GluN1/2B receptors, NMDA, [3H]ifenprodil, σ1 and σ2 receptors, receptor occupancy, PET imaging, Medicine, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1424-8247/15/8/960; https://doaj.org/toc/1424-8247

Access URL: https://doaj.org/article/36a2d0dd3b5a4ce9855afe64542033d1

Microfluidic radiosynthesis of [18F]FEMPT, a high affinity PET radiotracer for imaging serotonin receptors

Authors: Thomas Lee Collier, Steven H. Liang, J. John Mann, Neil Vasdev, J. S. Dileep Kumar

Source: Beilstein Journal of Organic Chemistry, Vol 13, Iss 1, Pp 2922-2927 (2017)

Subject Terms: agonist, fluorine-18, 5-HT1A, microfluidics, PET, Science, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://doaj.org/toc/1860-5397

Access URL: https://doaj.org/article/f2d3b8f0f0bc4f6984684e32c5bebcdd

Synthesis-free PET imaging of brown adipose tissue and TSPO via combination of disulfiram and 64CuCl2

Authors: Jing Yang, Jian Yang, Lu Wang, Anna Moore, Steven H. Liang, Chongzhao Ran

Source: Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/f6ec5eb5636649328d92c44b810d4366

Synthesis and preliminary PET imaging of 11C and 18F isotopologues of the ROS1/ALK inhibitor lorlatinib

Authors: Thomas Lee Collier, Marc D. Normandin, Nickeisha A. Stephenson, Eli Livni, Steven H. Liang, Dustin W. Wooten, Shadi A. Esfahani, Michael G. Stabin, Umar Mahmood, Jianqing Chen, Wei Wang, Kevin Maresca, Rikki N. Waterhouse, Georges El Fakhri, Paul Richardson, Neil Vasdev

Source: Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/c6a81b2a14fd4e259767853846c7c586