Characterizing Biophysical Parameters of Single TCR-pMHC Interactions Using Optical Tweezers

Authors: Stephens, Hannah M., Kirkpatrick, Evan, Mallis, Robert J., Reinherz, Ellis L., Lang, Matthew J.

Source: Methods in molecular biology. 2654:375-392

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN632332772&indx=1&recIds=ETOCRN632332772

Molecular design of the γδT cell receptor ectodomain encodes biologically fit ligand recognition in the absence of mechanosensing

Authors: Mallis, Robert J., Duke-Cohan, Jonathan S., Das, Dibyendu Kumar, Akitsu, Aoi, Luoma, Adrienne M., Banik, Debasis, Stephens, Hannah M., Tetteh, Paul W., Castro, Caitlin D., Krahnke, Sophie, Hussey, Rebecca E., Lawney, Brian, Brazin, Kristine N., Reche, Pedro A., Hwang, Wonmuk, Adams, Erin J., Lang, Matthew J., Reinherz, Ellis L.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2021 Jun . 118(26), 1-12.

Access URL: https://www.jstor.org/stable/27040813

Measuring αβ T-Cell Receptor-Mediated Mechanosensing Using Optical Tweezers Combined with Fluorescence Imaging

Authors: Stephens, Hannah M., Brazin, Kristine N., Mallis, Robert J., Feng, Yinnian, Banik, Debasis, Reinherz, Ellis L., Lang, Matthew J.

Source: Methods in molecular biology. 2478:727-753

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN630235945&indx=1&recIds=ETOCRN630235945

Correlating single-molecule interactions with T cell performance

Authors: Stephens, Hannah M., Akitsu, Aoi, Mallis, Robert J., Hwang, Wonmuk, Reinherz, Ellis L., Lang, Matthew J.

Source: In Biophysical Journal 8 February 2024 123(3) Supplement 1:244a-244a

Lon degrades stable substrates slowly but with enhanced processivity, redefining the attributes of a successful AAA+ protease.

Authors: Kasal, Meghann R., Kotamarthi, Hema Chandra, Johnson, Madeline M., Stephens, Hannah M., Lang, Matthew J., Sauer, Robert T., Baker, Tania A.

Source: Cell Reports; Sep2023, Vol. 42 Issue 9, pN.PAG-N.PAG, 1p