Quantifying the proportion of different cell types in the human cortex using DNA methylation profiles

Authors: Eilis Hannon, Emma L. Dempster, Jonathan P. Davies, Barry Chioza, Georgina E. T. Blake, Joe Burrage, Stefania Policicchio, Alice Franklin, Emma M. Walker, Rosemary A. Bamford, Leonard C. Schalkwyk, Jonathan Mill

Source: BMC Biology, Vol 22, Iss 1, Pp 1-19 (2024)

Subject Terms: DNA methylation, Brain, Neurons, Glia, Cellular heterogeneity, Alzheimer’s disease, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1741-7007

Access URL: https://doaj.org/article/3d312550f3bb4808b28fa6884c2ceea6

DNA methylation signatures of Alzheimer’s disease neuropathology in the cortex are primarily driven by variation in non-neuronal cell-types

Authors: Gemma Shireby, Emma L. Dempster, Stefania Policicchio, Rebecca G. Smith, Ehsan Pishva, Barry Chioza, Jonathan P. Davies, Joe Burrage, Katie Lunnon, Dorothea Seiler Vellame, Seth Love, Alan Thomas, Keeley Brookes, Kevin Morgan, Paul Francis, Eilis Hannon, Jonathan Mill

Source: Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/4898751694c340419ac1ca01ad423bfa