TGS1 mediates 2,2,7-trimethyl guanosine capping of the human telomerase RNA to direct telomerase dependent telomere maintenance

Authors: Valentina Buemi, Odessa Schillaci, Mariangela Santorsola, Deborah Bonazza, Pamela Veneziano Broccia, Annie Zappone, Cristina Bottin, Giulia Dell’Omo, Sylvie Kengne, Stefano Cacchione, Grazia Daniela Raffa, Silvano Piazza, Fabrizio d’Adda di Fagagna, Roberta Benetti, Maurizio Cortale, Fabrizio Zanconati, Giannino Del Sal, Stefan Schoeftner

Source: Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/695aa97a2df5484da202dfc53c1f242a

MiR‐182‐3p targets TRF2 and impairs tumor growth of triple‐negative breast cancer

Authors: Roberto Dinami, Luca Pompili, Eleonora Petti, Manuela Porru, Carmen D'Angelo, Serena Di Vito, Angela Rizzo, Virginia Campani, Giuseppe De Rosa, Alejandra Bruna, Violeta Serra, Miguel Mano, Mauro Giacca, Carlo Leonetti, Gennaro Ciliberto, Madalena Tarsounas, Antonella Stoppacciaro, Stefan Schoeftner, Annamaria Biroccio

Source: EMBO Molecular Medicine, Vol 15, Iss 1, Pp n/a-n/a (2023)

Subject Terms: miR‐182‐3p, target therapy, telomeres, TRF2, triple‐negative breast cancer, Medicine (General), R5-920, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1757-4676; https://doaj.org/toc/1757-4684

Access URL: https://doaj.org/article/329d8d14529b400796d6b5c09e60a4e4

SFPQ and NONO suppress RNA:DNA-hybrid-related telomere instability

Authors: Eleonora Petti, Valentina Buemi, Antonina Zappone, Odessa Schillaci, Pamela Veneziano Broccia, Roberto Dinami, Silvia Matteoni, Roberta Benetti, Stefan Schoeftner

Source: Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/f8f8d328c17a48d78dd6073e811e9d80

Loss of Human TGS1 Hypermethylase Promotes Increased Telomerase RNA and Telomere Elongation

Authors: Lu Chen, Caitlin M. Roake, Alessandra Galati, Francesca Bavasso, Emanuela Micheli, Isabella Saggio, Stefan Schoeftner, Stefano Cacchione, Maurizio Gatti, Steven E. Artandi, Grazia D. Raffa

Source: Cell Reports, Vol 30, Iss 5, Pp 1358-1372.e5 (2020)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124720300139; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/fb5097bebfa0486883060123f60f8335

TERRA regulate the transcriptional landscape of pluripotent cells through TRF1-dependent recruitment of PRC2

Authors: Rosa María Marión, Juan J Montero, Isabel López de Silanes, Osvaldo Graña-Castro, Paula Martínez, Stefan Schoeftner, José Alejandro Palacios-Fábrega, Maria A Blasco

Source: eLife, Vol 8 (2019)

Subject Terms: TRF1, telomere, pluripotency, TERRA, polycomb, lncRNA, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/44656; https://doaj.org/toc/2050-084X

Access URL: https://doaj.org/article/1b5741ae515b4e47ac161f4b7ae95b31

Sox4 Links Tumor Suppression to Accelerated Aging in Mice by Modulating Stem Cell Activation

Authors: Miguel Foronda, Paula Martínez, Stefan Schoeftner, Gonzalo Gómez-López, Ralph Schneider, Juana M. Flores, David G. Pisano, Maria A. Blasco

Source: Cell Reports, Vol 8, Iss 2, Pp 487-500 (2014)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124714005154; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/6a1efdbee50f4598af9c1085606d9d62