Tg1.4HBV-s-rec mice, a crossbred hepatitis B virus-transgenic model, develop mild hepatitis

Authors: Stefan Schefczyk, Xufeng Luo, Yaojie Liang, Mike Hasenberg, Bernd Walkenfort, Martin Trippler, Jonas Schuhenn, Kathrin Sutter, Mengji Lu, Heiner Wedemeyer, Hartmut H. Schmidt, Ruth Broering

Source: Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/d8033cbdd44a4c2e8375ba24f2d4d013

Hepatitis B surface antigen expression impairs endoplasmic reticulum stress-related autophagic flux by decreasing LAMP2

Authors: Yaojie Liang, Xufeng Luo, Stefan Schefczyk, Lorraine T. Muungani, Hui Deng, Baoju Wang, Hideo A. Baba, Mengji Lu, Heiner Wedemeyer, Hartmut H. Schmidt, Ruth Broering

Source: JHEP Reports, Vol 6, Iss 4, Pp 101012- (2024)

Subject Terms: HBV surface protein, lysosome, incomplete autophagy, liver cancer, cellular homeostasis, tumorigenesis, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589555924000132; https://doaj.org/toc/2589-5559

Access URL: https://doaj.org/article/021c294eb0fa4e82a3c04f7fbcee6c73

Poly(I:C) Induces Distinct Liver Cell Type-Specific Responses in Hepatitis B Virus-Transgenic Mice In Vitro, but Fails to Induce These Signals In Vivo

Authors: Stefan Schefczyk, Xufeng Luo, Yaojie Liang, Martin Trippler, Mengji Lu, Heiner Wedemeyer, Hartmut H. Schmidt, Ruth Broering

Source: Viruses, Vol 15, Iss 5, p 1203 (2023)

Subject Terms: hepatitis B virus, hepatitis B surface antigen, immune evasion, pattern recognition, toll-like receptor, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4915/15/5/1203; https://doaj.org/toc/1999-4915

Access URL: https://doaj.org/article/27478dd03825464ca096fa6d7be86116

Antiviral Toll-like Receptor Signaling in Non-Parenchymal Liver Cells Is Restricted to TLR3

Authors: Melanie Werner, Stefan Schefczyk, Martin Trippler, Juergen W. Treckmann, Hideo A. Baba, Guido Gerken, Joerg F. Schlaak, Ruth Broering

Source: Viruses, Vol 14, Iss 2, p 218 (2022)

Subject Terms: primary human non-parenchymal liver cells, hepatitis C virus, Toll-like receptors, interferons, Kupffer cells, liver sinusoidal endothelial cells, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4915/14/2/218; https://doaj.org/toc/1999-4915

Access URL: https://doaj.org/article/075b8a1bdb704ceca5b88dd01c481c13