Assessing the impact of airborne particulate pollution on human skin utilizing a novel human skin equivalent containing MUTZ‐3‐derived Langerhans cells

Authors: Amy Simpson, Teresa DiColandrea, Stefan Przyborski

Source: Bioengineering & Translational Medicine, Vol 10, Iss 2, Pp n/a-n/a (2025)

Subject Terms: air pollution, diesel particulate matter, human skin model, inflammatory cytokines, Langerhans cells, Chemical engineering, TP155-156, Biotechnology, TP248.13-248.65, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://doaj.org/toc/2380-6761

Access URL: https://doaj.org/article/da48ef20188b45999706002345b230cf

Current understanding of the interplay between extracellular matrix remodelling and gut permeability in health and disease

Authors: Aurora Vilardi, Stefan Przyborski, Claire Mobbs, Alessandro Rufini, Cristina Tufarelli

Source: Cell Death Discovery, Vol 10, Iss 1, Pp 1-11 (2024)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282, Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/2058-7716

Access URL: https://doaj.org/article/6133f5597d2d47d5bfe6bb010d74c82a

Modulation of the Nogo signaling pathway to overcome amyloid-β-mediated neurite inhibition in human pluripotent stem cell–derived neurites

Authors: Kirsty Goncalves, Stefan Przyborski

Source: Neural Regeneration Research, Vol 20, Iss 9, Pp 2645-2654 (2025)

Subject Terms: alzheimer’s disease, induced pluripotent stem cell, neurite outgrowth, neuron, nogo, rho a, rock, stem cell, three-dimensional culture, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://journals.lww.com/10.4103/NRR.NRR-D-23-01628; https://doaj.org/toc/1673-5374; https://doaj.org/toc/1876-7958

Access URL: https://doaj.org/article/243008fe5745493b93fd50036c5da18f

Bioengineering the Human Intestinal Mucosa and the Importance of Stromal Support for Pharmacological Evaluation In Vitro

Authors: Matthew Freer, Jim Cooper, Kirsty Goncalves, Stefan Przyborski

Source: Cells, Vol 13, Iss 22, p 1859 (2024)

Subject Terms: intestine, tissue engineering, drug discovery, fibroblast, keratinocyte growth factor, Caco-2, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/13/22/1859; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/fc269f1ba98042aebbeef4189be66158

Comparison of photodamage in non-pigmented and pigmented human skin equivalents exposed to repeated ultraviolet radiation to investigate the role of melanocytes in skin photoprotection

Authors: Paola De Los Santos Gomez, Lydia Costello, Kirsty Goncalves, Stefan Przyborski

Source: Frontiers in Medicine, Vol 11 (2024)

Subject Terms: UV radiation, human skin equivalents, pigmentation, photodamage, photoprotection, melanocytes, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmed.2024.1355799/full; https://doaj.org/toc/2296-858X

Access URL: https://doaj.org/article/9e3d16af3c08493a9988828d6290addc

An in vitro model to study immune activation, epithelial disruption and stromal remodelling in inflammatory bowel disease and fistulising Crohn’s disease

Authors: Claire L. Mobbs, Nicole J. Darling, Stefan Przyborski

Source: Frontiers in Immunology, Vol 15 (2024)

Subject Terms: inflammatory bowel disease, bioengineered, in vitro, disease modelling, barrier disruption, immune activation, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1357690/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/862eaf286ea0422fa2f183494d616f4d

Development of a novel in vitro strategy to understand the impact of shaving on skin health: combining tape strip exfoliation and human skin equivalent technology

Authors: Lydia Costello, Kirsty Goncalves, Victoria Maltman, Nicole Barrett, Kous Shah, Alison Stephens, Tereasa Dicolandrea, Ilaria Ambrogio, Erica Hodgson, Stefan Przyborski

Source: Frontiers in Medicine, Vol 10 (2023)

Subject Terms: exfoliation, stratum corneum, skin equivalent, shaving, inflammation, tape strip, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmed.2023.1236790/full; https://doaj.org/toc/2296-858X

Access URL: https://doaj.org/article/7dd5d158704f4ab59d2ec536700ed624

Cell Senescence-Independent Changes of Human Skin Fibroblasts with Age

Authors: Nicola Fullard, James Wordsworth, Ciaran Welsh, Victoria Maltman, Charlie Bascom, Ryan Tasseff, Robert Isfort, Lydia Costello, Rebekah-Louise Scanlan, Stefan Przyborski, Daryl Shanley

Source: Cells, Vol 13, Iss 8, p 659 (2024)

Subject Terms: skin, senescence, ageing, extracellular matrix, TGF, fibroblast, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/13/8/659; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/dc01f4ce86bc4473a783558f5164fe8f

Development of a mammalian neurosensory full‐thickness skin equivalent and its application to screen sensitizing stimuli

Authors: Matthew Freer, Nicole Darling, Kirsty Goncalves, Kevin J. Mills, Stefan Przyborski

Source: Bioengineering & Translational Medicine, Vol 8, Iss 3, Pp n/a-n/a (2023)

Subject Terms: capsaicin, inflammatory cytokines, neuroinflammation, neurosensitization, neurosensorial, skin model, Chemical engineering, TP155-156, Biotechnology, TP248.13-248.65, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://doaj.org/toc/2380-6761

Access URL: https://doaj.org/article/31cc99ccd48e49e89dea67b44c3642a9

Investigation into the effect of skin tone modulators and exogenous stress on skin pigmentation utilizing a novel bioengineered skin equivalent

Authors: Kirsty Goncalves, Paola De Los Santos Gomez, Lydia Costello, Lucy Smith, Hugh Mead, Amy Simpson, Stefan Przyborski

Source: Bioengineering & Translational Medicine, Vol 8, Iss 2, Pp n/a-n/a (2023)

Subject Terms: 3D cell culture, epidermal structure, in vitro, melanocytes, pigmentation, skin model, Chemical engineering, TP155-156, Biotechnology, TP248.13-248.65, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://doaj.org/toc/2380-6761

Access URL: https://doaj.org/article/e83ad36e9abd46b1a9da3635c5b0d308

Impact of the Physical Cellular Microenvironment on the Structure and Function of a Model Hepatocyte Cell Line for Drug Toxicity Applications

Authors: Benjamin Allcock, Wenbin Wei, Kirsty Goncalves, Henry Hoyle, Alisha Robert, Rebecca Quelch-Cliffe, Adam Hayward, Jim Cooper, Stefan Przyborski

Source: Cells, Vol 12, Iss 19, p 2408 (2023)

Subject Terms: mechanotransduction, bioengineering, 3D cell culture, cytoskeleton, hepatocyte, functionality, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/12/19/2408; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/d79c728faf0f44759e80508899294fb1

microRNA27a-3p mediates reduction of the Wnt antagonist sFRP-1 in systemic sclerosis

Authors: John Henderson, Sarah Wilkinson, Stefan Przyborski, Richard Stratton, Steven O’Reilly

Source: Epigenetics, Vol 16, Iss 7, Pp 808-817 (2021)

Subject Terms: systemic sclerosis, fibrosis, epigenetics, microrna, microrna targets, wnt, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1559-2294; https://doaj.org/toc/1559-2308

Access URL: https://doaj.org/article/032cfb5a56b14513b3195d1e103b5287

Bioengineering Novel in vitro Co-culture Models That Represent the Human Intestinal Mucosa With Improved Caco-2 Structure and Barrier Function

Authors: Nicole J. Darling, Claire L. Mobbs, Ariana L. González-Hau, Matthew Freer, Stefan Przyborski

Source: Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)

Subject Terms: Caco-2, fibroblast, 3D co-culture, epithelium, in vitro, intestinal, Biotechnology, TP248.13-248.65

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fbioe.2020.00992/full; https://doaj.org/toc/2296-4185

Access URL: https://doaj.org/article/ab5a7094683f44feaf2f2662d315e039

Recreating Tissue Structures Representative of Teratomas In Vitro Using a Combination of 3D Cell Culture Technology and Human Embryonic Stem Cells

Authors: Alejandro Hidalgo Aguilar, Lucy Smith, Dominic Owens, Rebecca Quelch, Stefan Przyborski

Source: Bioengineering, Vol 9, Iss 5, p 185 (2022)

Subject Terms: human embryonic stem cells, three-dimensional cell culture, tissue differentiation, teratoma assay, scaffold, Technology, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2306-5354/9/5/185; https://doaj.org/toc/2306-5354

Access URL: https://doaj.org/article/af55d75815774ed9996fc87de9fbb589

Disrupted alternative splicing for genes implicated in splicing and ciliogenesis causes PRPF31 retinitis pigmentosa

Authors: Adriana Buskin, Lili Zhu, Valeria Chichagova, Basudha Basu, Sina Mozaffari-Jovin, David Dolan, Alastair Droop, Joseph Collin, Revital Bronstein, Sudeep Mehrotra, Michael Farkas, Gerrit Hilgen, Kathryn White, Kuan-Ting Pan, Achim Treumann, Dean Hallam, Katarzyna Bialas, Git Chung, Carla Mellough, Yuchun Ding, Natalio Krasnogor, Stefan Przyborski, Simon Zwolinski, Jumana Al-Aama, Sameer Alharthi, Yaobo Xu, Gabrielle Wheway, Katarzyna Szymanska, Martin McKibbin, Chris F. Inglehearn, David J. Elliott, Susan Lindsay, Robin R. Ali, David H. Steel, Lyle Armstrong, Evelyne Sernagor, Henning Urlaub, Eric Pierce, Reinhard Lührmann, Sushma-Nagaraja Grellscheid, Colin A. Johnson, Majlinda Lako

Source: Nature Communications, Vol 9, Iss 1, Pp 1-19 (2018)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/39722a7de98941cab07e48fc0b8400de

The Cell-Permeable Derivative of the Immunoregulatory Metabolite Itaconate, 4-Octyl Itaconate, Is Anti-Fibrotic in Systemic Sclerosis

Authors: John Henderson, Sharadha Dayalan Naidu, Albena T. Dinkova-Kostova, Stefan Przyborski, Richard Stratton, Steven O′Reilly

Source: Cells, Vol 10, Iss 8, p 2053 (2021)

Subject Terms: systemic sclerosis, metabolism, fibrosis, itaconate, Nrf2, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/10/8/2053; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/7b6f959f7daa447986bc939a5788b72f

Rat Primary Hepatocytes Show Enhanced Performance and Sensitivity to Acetaminophen During Three-Dimensional Culture on a Polystyrene Scaffold Designed for Routine Use.

Authors: Maaike Schutte, Bridget Fox, Marc-Olivier Baradez, Alison Devonshire, Jesus Minguez, Maria Bokhari, Stefan Przyborski, Damian Marshall

Source: Assay & Drug Development Technologies; Oct2011, Vol. 9 Issue 5, p475-486, 12p

Subject Terms: LABORATORY rats, LIVER cells, PERFORMANCE evaluation, SENSITIVITY analysis, ACETAMINOPHEN, POLYSTYRENE, HEPATOTOXICOLOGY, TOXICITY testing, METABOLISM

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