A novel MYB::PAIP1 oncogenic fusion in pediatric blastic plasmacytoid dendritic cell neoplasm (BPDCN) is dependent on BCL2 expression and is sensitive to venetoclax

Authors: Hansen J. Kosasih, Gerry Healey, Margs S. Brennan, Stefan Bjelosevic, Teresa Sadras, Fatimah B. Jalud, Tasnia Ibnat, Ashley P. Ng, Chelsea Mayoh, Jie Mao, Gabor Tax, Louise E. A. Ludlow, Ricky W. Johnstone, Marco J. Herold, Seong L. Khaw, Charles E. deBock, Paul G. Ekert

Source: HemaSphere, Vol 8, Iss 2, Pp n/a-n/a (2024)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://doaj.org/toc/2572-9241

Access URL: https://doaj.org/article/aa411753f44943afbf2d90c36c201409

The Combination of Curaxin CBL0137 and Histone Deacetylase Inhibitor Panobinostat Delays KMT2A-Rearranged Leukemia Progression

Authors: Lin Xiao, Mawar Karsa, Emma Ronca, Angelika Bongers, Angelika Kosciolek, Ali El-Ayoubi, Jezrael L. Revalde, Janith A. Seneviratne, Belamy B. Cheung, Laurence C. Cheung, Rishi S. Kotecha, Andrea Newbold, Stefan Bjelosevic, Greg M. Arndt, Richard B. Lock, Ricky W. Johnstone, Andrei V. Gudkov, Katerina V. Gurova, Michelle Haber, Murray D. Norris, Michelle J. Henderson, Klaartje Somers

Source: Frontiers in Oncology, Vol 12 (2022)

Subject Terms: KMT2A-rearranged leukemia, infant leukemia, curaxin CBL0137, histone deacetylase inhibition, chromatin, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2022.863329/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/030ef39db2a746f68cb7bcf2cf823422

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