A pharmacogenomic assessment of psychiatric adverse drug reactions to levetiracetam

Authors: Campbell, Ciarán, McCormack, Mark, Patel, Sonn, Stapleton, Caragh, Bobbili, Dheeraj, Krause, Roland, Depondt, Chantal, Sills, Graeme J., Koeleman, Bobby P., Striano, Pasquale, Zara, Federico, Sander, Josemir W., Lerche, Holger, Kunz, Wolfram S., Stefansson, Kari, Stefansson, Hreinn, Doherty, Colin P., Heinzen, Erin L., Scheffer, Ingrid E., Goldstein, David B., O'Brien, Terence, Cotter, David, Berkovic, Samuel F., Sisodiya, Sanjay M., Delanty, Norman, Cavalleri, Gianpiero L.

Source: Epilepsia. 63(6):1563-1570

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100165184172.0x000001&indx=1&recIds=ETOCvdc_100165184172.0x000001

The impact of donor and recipient common clinical and genetic variation on estimated glomerular filtration rate in a European renal transplant population

Authors: Stapleton, Caragh P., Heinzel, Andreas, Guan, Weihua, van der Most, Peter J., van Setten, Jessica, Lord, Graham M., Keating, Brendan J., Israni, Ajay K., de Borst, Martin H., Bakker, Stephan J.L., Snieder, Harold, Weale, Michael E., Delaney, Florence, Hernandez-Fuentes, Maria P., Reindl-Schwaighofer, Roman, Oberbauer, Rainer, Jacobson, Pamala A., Mark, Patrick B., Chapman, Fiona A., Phelan, Paul J., Kennedy, Claire, Sexton, Donal, Murray, Susan, Jardine, Alan, Traynor, Jamie P., McKnight, Amy Jayne, Maxwell, Alexander P., Smyth, Laura J., Oetting, William S., Matas, Arthur J., Mannon, Roslyn B., Schladt, David P., Iklé, David N., Cavalleri, Gianpiero L. ^*, Conlon, Peter J. ^*

Source: In American Journal of Transplantation August 2019 19(8):2262-2273

Monogenic causes of chronic kidney disease in adults

Authors: Connaughton, Dervla M., Kennedy, Claire, Shril, Shirlee, Mann, Nina, Murray, Susan L., Williams, Patrick A., Conlon, Eoin, Nakayama, Makiko, van der Ven, Amelie T., Ityel, Hadas, Kause, Franziska, Kolvenbach, Caroline M., Dai, Rufeng, Vivante, Asaf, Braun, Daniela A., Schneider, Ronen, Kitzler, Thomas M., Moloney, Brona, Moran, Conor P., Smyth, John S., Kennedy, Alan, Benson, Katherine, Stapleton, Caragh, Denton, Mark, Magee, Colm, O’Seaghdha, Conall M., Plant, William D., Griffin, Matthew D., Awan, Atif, Sweeney, Clodagh, Mane, Shrikant M., Lifton, Richard P., Griffin, Brenda, Leavey, Sean, Casserly, Liam, de Freitas, Declan G., Holian, John, Dorman, Anthony, Doyle, Brendan, Lavin, Peter J., Little, Mark A., Conlon, Peter J., Hildebrandt, Friedhelm

Source: In Kidney International April 2019 95(4):914-928

Utility of Genomic Testing after Renal Biopsy

Authors: Murray, Susan L., Dorman, Anthony, Benson, Katherine A., Connaughton, Dervla M., Stapleton, Caragh P., Fennelly, Neil K., Kennedy, Claire, McDonnell, Ciara A., Kidd, Kendrah, Cormican, Sarah M., Ryan, Louise A., Lavin, Peter, Little, Mark A., Bleyer, Anthony J., Doyle, Brendan, Cavalleri, Gianpiero L., Hildebrandt, Friedhelm, Conlon, Peter J.

Source: American journal of nephrology. 51(1):43-53

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100096476693.0x000001&indx=1&recIds=ETOCvdc_100096476693.0x000001

An Exome Sequencing Study of 10 Families with IgA Nephropathy

Authors: Stapleton, Caragh P., Kennedy, Claire, Fennelly, Neil K., Murray, Susan L., Connaughton, Dervla M., Dorman, Anthony M., Doyle, Brendan, Cavalleri, Gianpiero L., Conlon, Peter J.

Source: Nephron journals. 144(2):72-83

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100096979979.0x000001&indx=1&recIds=ETOCvdc_100096979979.0x000001

Polygenic risk score as a determinant of risk of non-melanoma skin cancer in a European-descent renal transplant cohort

Authors: Stapleton, Caragh P., Birdwell, Kelly A., McKnight, Amy Jayne, Maxwell, Alexander P., Mark, Patrick B., Sanders, M. Lee, Chapman, Fiona A., van Setten, Jessica, Phelan, Paul J., Kennedy, Claire, Jardine, Alan, Traynor, Jamie P., Keating, Brendan, Conlon, Peter J. ^**, Cavalleri, Gianpiero L. ^*

Source: In American Journal of Transplantation March 2019 19(3):801-810

FC033: Genome-Wide Association Meta-Analysis Identifies Novel Loci for Kidney Failure

Authors: van der Most, Peter, Wang, Siqi, Guan, Weihua, Schladt, David, Loza, Bao-LI, Stapleton, Caragh, Heinzel, Andreas, Israni, Ajay, Jacobson, Pamala, Keating, Brendan, Conlon, Peter, Oberbauer, Rainer, Snieder, Harold, De Borst, Martin

Source: Nephrology dialysis transplantation. 37(Supplement 3)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100152558595.0x000001&indx=1&recIds=ETOCvdc_100152558595.0x000001

Long‐ and short‐term outcomes in renal allografts with deceased donors: A large recipient and donor genome‐wide association study

Authors: Hernandez‐Fuentes, Maria P., Franklin, Christopher, Rebollo‐Mesa, Irene, Mollon, Jennifer, Delaney, Florence, Perucha, Esperanza, Stapleton, Caragh, Borrows, Richard, Byrne, Catherine, Cavalleri, Gianpiero, Clarke, Brendan, Clatworthy, Menna, Feehally, John, Fuggle, Susan, Gagliano, Sarah A., Griffin, Sian, Hammad, Abdul, Higgins, Robert, Jardine, Alan, Keogan, Mary, Leach, Timothy, MacPhee, Iain, Mark, Patrick B., Marsh, James, Maxwell, Peter, McKane, William, McLean, Adam, Newstead, Charles, Augustine, Titus, Phelan, Paul, Powis, Steve, Rowe, Peter, Sheerin, Neil, Solomon, Ellen, Stephens, Henry, Thuraisingham, Raj, Trembath, Richard, Topham, Peter, Vaughan, Robert, Sacks, Steven H., Conlon, Peter, Opelz, Gerhard, Soranzo, Nicole, Weale, Michael E., Lord, Graham M.

Source: American journal of transplantation. 18(6):1370-1379

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100114343021.0x000001&indx=1&recIds=ETOCvdc_100114343021.0x000001

Clinical Heterogeneity in Familial IgA Nephropathy

Authors: Fennelly, Neil K., Kennedy, Claire, Jenkinson, Allan C., Connaughton, Dervla M., Stapleton, Caragh, Dorman, Anthony M., Doyle, Brendan, Conlon, Peter J.

Source: Nephron journals. 139(1):63-69

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100084716028.0x000001&indx=1&recIds=ETOCvdc_100084716028.0x000001

Polygenic risk score of non‐melanoma skin cancer predicts post‐transplant skin cancer across multiple organ types.

Authors: Stapleton, Caragh P.¹ (AUTHOR), Chang, Bao‐Li² (AUTHOR), Keating, Brendan J.² (AUTHOR), Conlon, Peter J.^3,4 (AUTHOR) peterconlon@beaumont.ie, Cavalleri, Gianpiero L.¹ (AUTHOR) gcavalleri@rcsi.ie

Source: Clinical Transplantation. Aug2020, Vol. 34 Issue 8, p1-5. 5p.

Subject Terms: *SKIN cancer, *BASAL cell carcinoma, *LIVER transplantation, *TRANSPLANTATION of organs, tissues, etc., *SQUAMOUS cell carcinoma

FO027DIAGNOSTIC UTILITY OF NEXT GENERATION SEQUENCING TECHNIQUES IN PATIENTS WITH FAMILIAL KIDNEY DISEASE WHO HAVE UNDERGONE PERCUTANEOUS NATIVE KIDNEY BIOPSY

Authors: Murray, Susan, Dorman, Anthony, Mcdonnell, Ciara, Fennelly, Neil, Kennedy, Claire, Connaughton, Dervla M, Benson, Katherine, Stapleton, Caragh, Cormican, Sarah, Ryan, Louise, Bleyer, Anthony J, Kidd, Kendrah, Doyle, Brendan, Gianpiero, Cavalleri, Hildebrandt, Friedhelm, Conlon, Peter

Source: Nephrology dialysis transplantation. 34(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100097294699.0x000001&indx=1&recIds=ETOCvdc_100097294699.0x000001

The utility of a genetic kidney disease clinic employing a broad range of genomic testing platforms: experience of the Irish Kidney Gene Project.

Authors: Elhassan, Elhussein A. E., Murray, Susan L., Connaughton, Dervla M., Kennedy, Claire, Cormican, Sarah, Cowhig, Cliona, Stapleton, Caragh, Little, Mark A., Kidd, Kendrah, Bleyer, Anthony J., Živná, Martina, Kmoch, Stanislav, Fennelly, Neil K., Doyle, Brendan, Dorman, Anthony, Griffin, Matthew D., Casserly, Liam, Harris, Peter C., Hildebrandt, Friedhelm, Cavalleri, Gianpiero L.

Source: Journal of Nephrology (JNonline); Jul2022, Vol. 35 Issue 6, p1655-1665, 11p

Role of Common Genetic Variants for Drug-Resistance to Specific Anti-Seizure Medications.

Authors: Wolking, Stefan, Campbell, Ciarán, Stapleton, Caragh, McCormack, Mark, Delanty, Norman, Depondt, Chantal, Johnson, Michael R., Koeleman, Bobby P. C., Krause, Roland, Kunz, Wolfram S., Marson, Anthony G., Sander, Josemir W., Sills, Graeme J., Striano, Pasquale, Zara, Federico, Sisodiya, Sanjay M., Cavalleri, Gianpiero L., Lerche, Holger

Source: Frontiers in Pharmacology; 6/9/2021, Vol. 12, p1-7, 7p

Subject Terms: PHARMACOGENOMICS, ANTICONVULSANTS, GENETIC variation, MEDICAL personnel, NEUROBEHAVIORAL disorders, GENOME-wide association studies

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A genome‐wide association study of sodium levels and drug metabolism in an epilepsy cohort treated with carbamazepine and oxcarbazepine.

Authors: Berghuis, Bianca, Stapleton, Caragh, Sonsma, Anja C. M., Hulst, Janic, Haan, Gerrit‐Jan, Lindhout, Dick, Demurtas, Rita, Krause, Roland, Depondt, Chantal, Kunz, Wolfram S., Zara, Federico, Striano, Pasquale, Craig, John, Auce, Pauls, Marson, Anthony G., Stefansson, Hreinn, O'Brien, Terence J., Johnson, Michael R., Sills, Graeme J., Wolking, Stefan

Source: Epilepsia Open; Mar2019, Vol. 4 Issue 1, p102-109, 8p

Subject Terms: DRUG metabolism, CARBAMAZEPINE, ANTICONVULSANTS, VALPROIC acid, EPILEPSY, SODIUM, THERAPEUTICS

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FO027 DIAGNOSTIC UTILITY OF NEXT GENERATION SEQUENCING TECHNIQUES IN PATIENTS WITH FAMILIAL KIDNEY DISEASE WHO HAVE UNDERGONE PERCUTANEOUS NATIVE KIDNEY BIOPSY.

Authors: Murray, Susan, Dorman, Anthony, Mcdonnell, Ciara, Fennelly, Neil, Kennedy, Claire, Connaughton, Dervla M, Benson, Katherine, Stapleton, Caragh, Cormican, Sarah, Ryan, Louise, Bleyer, Anthony J, Kidd, Kendrah, Doyle, Brendan, Gianpiero, Cavalleri, Hildebrandt, Friedhelm, Conlon, Peter

Source: Nephrology Dialysis Transplantation; 2019 Supplement, Vol. 34, pN.PAG-N.PAG, 1p

Subject Terms: RENAL biopsy, GENETIC disorders, KIDNEY diseases, CHILDREN'S hospitals