De novo design of high-affinity protein binders with AlphaProteo

Authors: Zambaldi, Vinicius, La, David, Chu, Alexander E., Patani, Harshnira, Danson, Amy E., Kwan, Tristan O. C., Frerix, Thomas, Schneider, Rosalia G., Saxton, David, Thillaisundaram, Ashok, Wu, Zachary, Moraes, Isabel, Lange, Oskar, Papa, Eliseo, Stanton, Gabriella, Martin, Victor, Singh, Sukhdeep, Wong, Lai H., Bates, Russ, Kohl, Simon A., Abramson, Josh, Senior, Andrew W., Alguel, Yilmaz, Wu, Mary Y., Aspalter, Irene M., Bentley, Katie, Bauer, David L. V., Cherepanov, Peter, Hassabis, Demis, Kohli, Pushmeet, Fergus, Rob, Wang, Jue

Subject Terms: Quantitative Biology - Biomolecules

Access URL: http://arxiv.org/abs/2409.08022