No developmental toxicity observed with dolutegravir in rat whole embryo culture

Authors: Posobiec, Lorraine M., Chapman, Sharon P., Murzyn, Stacia F., Rendemonti, Joyce E., Stanislaus, Dinesh J., Romach, Elizabeth H.

Source: Birth defects research. 113(16):1190-1197

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100131021096.0x000001&indx=1&recIds=ETOCvdc_100131021096.0x000001

Absence of developmental and reproductive toxicity in animals exposed to dolutegravir

Authors: Stanislaus, Dinesh J., Posobiec, Lorraine M., Laffan, Susan B., Solomon, Howard M., Ziejewski, Mary K., Romach, Elizabeth H.

Source: Birth defects research. 112(3):245-261

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100097856855.0x000001&indx=1&recIds=ETOCvdc_100097856855.0x000001

Comparing rat and rabbit embryo-fetal developmental toxicity data for 379 pharmaceuticals: on systemic dose and developmental effects

Authors: Theunissen, Peter T., Beken, Sonia, Beyer, Bruce, Breslin, William J., Cappon, Gregg D., Chen, Connie L., Chmielewski, Gary, de Schaepdrijver, Luc, Enright, Brian, Foreman, Jennifer E., Harrouk, Wafa, Hew, Kok-Wah, Hoberman, Alan M., Y. Hui, Julia, Knudsen, Thomas B., Laffan, Susan B., Makris, Susan L., Martin, Matthew, McNerney, Mary Ellen, Siezen, Christine L., Stanislaus, Dinesh J., Stewart, Jane, Thompson, Kary E., Tornesi, Belen, Van der Laan, Jan Willem, Weinbauer, Gerhard F., Wood, Sandra, Piersma, Aldert H.

Source: Critical reviews in toxicology. 47(5):409-421

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100103787320.0x000001&indx=1&recIds=ETOCvdc_100103787320.0x000001

Comparison of rat and rabbit embryo–fetal developmental toxicity data for 379 pharmaceuticals: on the nature and severity of developmental effects

Authors: Theunissen, Peter T., Beken, Sonja, Beyer, Bruce K., Breslin, William J., Cappon, Gregg D., Chen, Connie L., Chmielewski, Gary, De Schaepdrijver, Luc, Enright, Brian, Foreman, Jennifer E., Harrouk, Wafa, Hew, Kok-Wah, Hoberman, Alan M., Hui, Julia Y., Knudsen, Thomas B., Laffan, Susan B., Makris, Susan L., Martin, Matt, McNerney, Mary Ellen, Siezen, Christine L., Stanislaus, Dinesh J., Stewart, Jane, Thompson, Kary E., Tornesi, Belen, Van der Laan, Jan Willem, Weinbauer, Gerhard F., Wood, Sandra, Piersma, Aldert H.

Source: Critical reviews in toxicology. 46(10):900-910

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100103787182.0x000001&indx=1&recIds=ETOCvdc_100103787182.0x000001

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Pyridyl-2,5-Diketopiperazinesas Potent, Selective, and Orally Bioavailable Oxytocin Antagonists:Synthesis, Pharmacokinetics, and In Vivo Potency.

Authors: Borthwick, Alan D., Liddle, John, Davies, Dave E., Exall, Anne M., Hamlett, Christopher, Hickey, Deirdre M., Mason, Andrew M., Smith, Ian E. D., Nerozzi, Fabrizio, Peace, Simon, Pollard, Derek, Sollis, Steve L., Allen, Michael J., Woollard, Patrick M., Pullen, Mark A., Westfall, Timothy D., Stanislaus, Dinesh J.

Source: Journal of Medicinal Chemistry; Jan2012, Vol. 55 Issue 2, p783-796, 14p

Identification of drug‐induced hyper‐ or hypoprolactinemia in the female rat based on general and reproductive toxicity study parameters

Authors: Rehm, Sabine, Stanislaus, Dinesh J., Wier, Patrick J.

Source: Birth Defects Research Part B: Developmental and Reproductive Toxicology; June 2007, Vol. 80 Issue: 3 p253-257, 5p

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