Automated fiducial-based alignment of cryo-electron tomography tilt series in Dynamo

Authors: Coray, Raffaele ¹, Navarro, Paula ^{2, 3}, Scaramuzza, Stefano ², Stahlberg, Henning ^{2, 4}, Castaño-Díez, Daniel ^{1, 2, 5, ∗}

Source: In Structure 3 October 2024 32(10):1808-1819

Rapid iPSC inclusionopathy models shed light on formation, consequence, and molecular subtype of α-synuclein inclusions

Authors: Lam, Isabel ^{1, 2, 3, 28}, Ndayisaba, Alain ^{1, 2, 3, 4, 28}, Lewis, Amanda J. ⁵, Fu, YuHong ⁶, Sagredo, Giselle T. ⁶, Kuzkina, Anastasia ^{1, 2, 3}, Zaccagnini, Ludovica ⁷, Celikag, Meral ⁷, Sandoe, Jackson ⁸, Sanz, Ricardo L. ^{1, 2, 3}, Vahdatshoar, Aazam ^{1, 2}, Martin, Timothy D. ^{3, 9, 10}, Morshed, Nader ^{3, 10, 11, 12}, Ichihashi, Toru ¹³, Tripathi, Arati ^{1, 3}, Ramalingam, Nagendran ^{1, 3}, Oettgen-Suazo, Charlotte ^{1, 2}, Bartels, Theresa ⁸, Boussouf, Manel ^{1, 2}, Schäbinger, Max ^{1, 2}, Hallacli, Erinc ^{1, 2, 3}, Jiang, Xin ¹⁴, Verma, Amrita ^{1, 2}, Tea, Challana ¹⁵, Wang, Zichen ¹⁵, Hakozaki, Hiroyuki ¹⁵, Yu, Xiao ^{1, 2}, Hyles, Kelly ^{1, 2}, Park, Chansaem ^{1, 2}, Wang, Xinyuan ^{1, 2, 3}, Theunissen, Thorold W. ⁸, Wang, Haoyi ⁸, Jaenisch, Rudolf ⁸, Lindquist, Susan ^{8, 10, 29}, Stevens, Beth ^{3, 10, 11, 12}, Stefanova, Nadia ⁴, Wenning, Gregor ^{4, 29}, van de Berg, Wilma D.J. ¹⁶, Luk, Kelvin C. ¹⁷, Sanchez-Pernaute, Rosario ^{18, 19}, Gómez-Esteban, Juan Carlos ¹⁸, Felsky, Daniel ^{20, 21}, Kiyota, Yasujiro ¹³, Sahni, Nidhi ^{22, 23}, Yi, S. Stephen ²⁴, Chung, Chee Yeun ¹⁴, Stahlberg, Henning ⁵, Ferrer, Isidro ²⁵, Schöneberg, Johannes ¹⁵, Elledge, Stephen J. ^{3, 9, 10}, Dettmer, Ulf ^{1, 3}, Halliday, Glenda M. ^{6, 26}, Bartels, Tim ⁷, Khurana, Vikram ^{1, 2, 3, 12, 26, 27, 30, ∗}

Source: In Neuron 4 September 2024 112(17):2886-2909

Trans‐seeding of Alzheimer‐related tau protein by a yeast prion

Authors: Flach, Martin, Leu, Cedric, Martinisi, Alfonso, Skachokova, Zhiva, Frank, Stephan, Tolnay, Markus, Stahlberg, Henning, Winkler, David T.

Source: Alzheimer's & dementia. 18(12):2481-2492

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100169086836.0x000001&indx=1&recIds=ETOCvdc_100169086836.0x000001

Allosteric control of type I-A CRISPR-Cas3 complexes and establishment as effective nucleic acid detection and human genome editing tools

Authors: Hu, Chunyi, Ni, Dongchun, Nam, Ki Hyun, Majumdar, Sonali, McLean, Justin, Stahlberg, Henning, Terns, Michael P., Ke, Ailong

Source: In Molecular Cell 4 August 2022 82(15):2754-2768

Structural basis of SIRT7 nucleosome engagement and substrate specificity.

Authors: Moreno-Yruela, Carlos, Ekundayo, Babatunde E., Foteva, Polina N., Ni, Dongchun, Calvino-Sanles, Esther, Stahlberg, Henning, Fierz, Beat

Source: Nature Communications; 2/3/2025, Vol. 16 Issue 1, p1-15, 15p

Subject Terms: LIFE sciences, SMALL molecules, BIOCHEMICAL substrates, CYTOLOGY, DEACYLATION

Identification of a binding site for small molecule inhibitors targeting human TRPM4.

Authors: Ekundayo, Babatunde, Arullampalam, Prakash, Gerber, Christian E., Hämmerli, Anne-Flore, Guichard, Sabrina, Boukenna, Mey, Ross-Kaschitza, Daniela, Lochner, Martin, Rougier, Jean-Sebastien, Stahlberg, Henning, Abriel, Hugues, Ni, Dongchun

Source: Nature Communications; 1/19/2025, Vol. 16 Issue 1, p1-14, 14p

Subject Terms: LIFE sciences, AMINOBENZOIC acids, SMALL molecules, BINDING sites, MONOVALENT cations

Joint Ptychographic Tomography of Frozen Hydrated Proteins

Authors: Varnavides Georgios, Yu Yue, Küçükoğlu Berk, Ribet Stephanie, Scott Mary, Stahlberg Henning, Ophus Colin

Source: BIO Web of Conferences, Vol 129, p 11005 (2024)

Subject Terms: single-particle analysis, ptychography, tomography, phase-retrieval, Microbiology, QR1-502, Physiology, QP1-981, Zoology, QL1-991

File Description: electronic resource

Relation: https://www.bio-conferences.org/articles/bioconf/pdf/2024/48/bioconf_emc2024_11005.pdf; https://doaj.org/toc/2117-4458

Access URL: https://doaj.org/article/40840022846642098569b5948d319bde

Low-dose cryo-electron ptychography of proteins at sub-nanometer resolution

Authors: Kucukoglu Berk, Mohammed Inayathulla, Guerrero-Ferreira Ricardo C., Ribet Stephanie M., Varnavides Georgios, Leidl Max Leo, Lau Kelvin, Nazarov Sergey, Myasnikov Alexander, Sachse Carsten, Müller-Caspary Knut, Ophus Colin, Stahlberg Henning

Source: BIO Web of Conferences, Vol 129, p 21011 (2024)

Subject Terms: 4d-stem, ptychography, cryo-em, low-dose, Microbiology, QR1-502, Physiology, QP1-981, Zoology, QL1-991

File Description: electronic resource

Relation: https://www.bio-conferences.org/articles/bioconf/pdf/2024/48/bioconf_emc2024_21011.pdf; https://doaj.org/toc/2117-4458

Access URL: https://doaj.org/article/c9aaf32bab2a4d17bb6a8239079da40f

Preliminary studies on iterative transform algorithms for 3D reconstruction of 2D crystals

Authors: Zeng, Xiangyan, Chen, Yen-Wei, Hughes, Owen, Stahlberg, Henning

Source: The 2nd International Conference on Software Engineering and Data Mining Software Engineering and Data Mining (SEDM), 2010 2nd International Conference on. :675-679 Jun, 2010

Relation: 2010 2nd International Conference on Software Engineering and Data Mining (SEDM)

Identification of a Dps contamination in Mitomycin-C–induced expression of Colicin Ia

Authors: Pipercevic, Joka, Jakob, Roman P., Righetto, Ricardo D., Goldie, Kenneth N., Stahlberg, Henning, Maier, Timm, Hiller, Sebastian

Source: In BBA - Biomembranes 1 July 2021 1863(7)

Structural Basis of Drug Recognition by the Multidrug Transporter ABCG2

Authors: Kowal, Julia, Ni, Dongchun, Jackson, Scott M., Manolaridis, Ioannis, Stahlberg, Henning, Locher, Kaspar P.

Source: In Journal of Molecular Biology 25 June 2021 433(13)

Single Particle Analysis for High-Resolution 2D Electron Crystallography

Authors: Righetto, Ricardo, Stahlberg, Henning

Source: Methods in molecular biology. 2215:267-286

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN625351910&indx=1&recIds=ETOCRN625351910

Modulation of ABCG2 Transporter Activity by Ko143 Derivatives.

Authors: Yu, Qin, Dehghani-Ghahnaviyeh, Sepehr, Rasouli, Ali, Sadurni, Anna, Kowal, Julia, Bang-Soerensen, Rose, Wen, Po-Chao, Tinzl-Zechner, Melanie, Irobalieva, Rossitza N., Ni, Dongchun, Stahlberg, Henning, Altmann, Karl-Heinz, Tajkhorshid, Emad, Locher, Kaspar P.

Source: ACS Chemical Biology; 11/15/2024, Vol. 19 Issue 11, p2304-2313, 10p

Distinct ultrastructural phenotypes of glial and neuronal alpha-synuclein inclusions in multiple system atrophy.

Authors: Böing, Carolin¹, Fabrizio, Marta Di^2,3, Burger, Domenic^2,3, Bol, John G J M⁴, Huisman, Evelien⁴, Rozemuller, Annemieke J M^5,6, Berg, Wilma D J van de^4,6, Stahlberg, Henning^2,3, Lewis, Amanda J^2,3, amanda.lewis@epfl.ch

Source: Brain: A Journal of Neurology; Nov2024, Vol. 147 Issue 11, p3727-3741, 15p

Cryo-EM, X-ray diffraction, and atomistic simulations reveal determinants for the formation of a supramolecular myelin-like proteolipid lattice

Authors: Ruskamo, Salla, Krokengen, Oda C., Kowal, Julia, Nieminen, Tuomo ^**, Lehtimäki, Mari, Raasakka, Arne, Dandey, Venkata P., Vattulainen, Ilpo ^**, Stahlberg, Henning, Kursula, Petri

Source: In Journal of Biological Chemistry 26 June 2020 295(26):8692-8705

New insights on the structure of alpha-synuclein fibrils using cryo-electron microscopy

Authors: Guerrero-Ferreira, Ricardo, Kovacik, Lubomir, Ni, Dongchun, Stahlberg, Henning

Source: In Current Opinion in Neurobiology April 2020 61:89-95

Microfluidic protein isolation and sample preparation for high-resolution cryo-EM

Authors: Schmidli, Claudio, Albiez, Stefan, Rima, Luca, Righetto, Ricardo, Mohammed, Inayatulla, Oliva, Paolo, Kovacik, Lubomir, Stahlberg, Henning, Braun, Thomas

Source: Proceedings of the National Academy of Sciences of the United States of America, 2019 Jul . 116(30), 15007-15012.

Access URL: https://www.jstor.org/stable/26848322

Grayscale e-beam lithography: Effects of a delayed development for well-controlled 3D patterning

Authors: Mortelmans, Thomas, Kazazis, Dimitrios, Guzenko, Vitaliy A., Padeste, Celestino, Braun, Thomas, Stahlberg, Henning, Li, Xiaodan, Ekinci, Yasin

Source: In Microelectronic Engineering 15 March 2020 225

The Contorsbody, an antibody format for agonism: Design, structure, and function

Authors: Georges, Guy J., Dengl, Stefan, Bujotzek, Alexander, Hesse, Friederike, Fischer, Jens A.A., Gärtner, Achim, Benz, Jörg, Lauer, Matthias E., Ringler, Philippe, Stahlberg, Henning, Plath, Friederike, Brinkmann, Ulrich, Imhof-Jung, Sabine

Source: In Computational and Structural Biotechnology Journal 2020 18:1210-1220

Rendering graphene supports hydrophilic with non-covalent aromatic functionalization for transmission electron microscopy

Authors: Pantelic, Radosav S., Fu, Wangyang, Schoenenberger, Christian, Stahlberg, Henning

Subject Terms: Physics - Biological Physics, Condensed Matter - Materials Science

Access URL: http://arxiv.org/abs/1403.6976