Comparison of P‐glycoprotein function in peripheral blood mononuclear cells ex vivo in stable Black and White male and female kidney transplant recipients

Authors: Tornatore, Kathleen M., Attwood, Kris, Brazeau, Daniel, Sprowl, Jason, Chang, Shirley, Gundroo, Aijaz, Minderman, Hans, Venuto, Rocco C.

Source: Clinical and translational science. 16(2):184-192

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100173635288.0x000001&indx=1&recIds=ETOCvdc_100173635288.0x000001

SLCO1B1 Pharmacogenetics in Pediatrics

Authors: Ramsey, Laura B., Sprowl, Jason A., Leeder, J. Steven, Wagner, Jonathan B.

Source: In Advances in Molecular Pathology November 2022 5(1):109-118

Regulation of Drug Transport Proteins—From Mechanisms to Clinical Impact: A White Paper on Behalf of the International Transporter Consortium

Authors: Brouwer, Kim L.R., Evers, Raymond, Hayden, Elizabeth, Hu, Shuiying, Li, Cindy Yanfei, Meyer zu Schwabedissen, Henriette E., Neuhoff, Sibylle, Oswald, Stefan, Piquette‐Miller, Micheline, Saran, Chitra, Sjöstedt, Noora, Sprowl, Jason A., Stahl, Simone H., Yue, Wei

Source: Clinical pharmacology & therapeutics. 112(3):461-484

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100158381727.0x000001&indx=1&recIds=ETOCvdc_100158381727.0x000001

Transporters and Toxicity: Insights From the International Transporter Consortium Workshop 4

Authors: Hafey, Michael J., Aleksunes, Lauren M., Bridges, Christy C., Brouwer, Kenneth R., Chien, Huan‐Chieh, Leslie, Elaine M., Hu, Shuiying, Li, Yang, Shen, Jinshan, Sparreboom, Alex, Sprowl, Jason, Tweedie, Donald, Lai, Yurong

Source: Clinical pharmacology & therapeutics. 112(3):527-539

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100158381744.0x000001&indx=1&recIds=ETOCvdc_100158381744.0x000001

Influence of Tyrosine Kinase Inhibition on Organic Anion Transporting Polypeptide 1B3-Mediated Uptake

Authors: Hove, Vusumuzi N., Anderson, Kenneth, Hayden, Elizabeth R., Pasquariello, Kyle Z., Gibson, Alice A., Shen, Shichen, Qu, Jun, Jin, Yan, Miecznikowski, Jeffrey C., Hu, Shuiying, Sprowl, Jason A. ^*

Source: In Molecular Pharmacology June 2022 101(6):381-389

Current Understanding of Membrane Transporters as Regulators or Targets for Cisplatin-Induced Hearing Loss

Authors: Pasquariello, Kyle Z., Dey, Jason M., Sprowl, Jason A. ^*

Source: In Molecular Pharmacology October 2021 100(4):348-355

Impact of Drug-Mediated Inhibition of Intestinal Transporters on Nutrient and Endogenous Substrate Disposition...an Afterthought?

Authors: Kharve, Kshitee, Engley, Andrew S., Paine, Mary F., Sprowl, Jason A.

Source: Pharmaceutics; Apr2024, Vol. 16 Issue 4, p447, 16p

Subject Terms: MEMBRANE transport proteins, INTESTINES, DRUG absorption, DRUG interactions, BILE acids, VITAMIN B1, FOLIC acid

Drug induced organ toxicity: Transporter roles and derisking approaches

Authors: Sprowl, Jason

Source: In Drug Metabolism and Pharmacokinetics April 2024 55 Supplement

Mitigation of acute kidney injury by cell-cycle inhibitors that suppress both CDK4/6 and OCT2 functions

Authors: Pabla, Navjotsingh, Gibson, Alice A., Buege, Mike, Ong, Su Sien, Li, Lie, Hu, Shuiying, Du, Guoqing, Sprowl, Jason A., Vasilyeva, Aksana, Janke, Laura J., Schlatter, Eberhard, Chen, Taosheng, Ciarimboli, Giuliano, Sparreboom, Alex

Source: Proceedings of the National Academy of Sciences of the United States of America, 2015 Apr . 112(16), 5231-5236.

Access URL: https://www.jstor.org/stable/26462339

Uptake Carriers and Oncology Drug Safety

Authors: Sprowl, Jason A., Sparreboom, Alex ^*

Source: In Drug Metabolism and Disposition April 2014 42(4):611-622

Polymorphic Transporters and Platinum Pharmacodynamics

Authors: Sprowl, Jason A., Ness, Rachel A., Sparreboom, Alex ^⁎

Source: In Drug Metabolism and Pharmacokinetics 2013 28(1):19-27

Oxaliplatin-induced neurotoxicity is dependent on the organic cation transporter OCT2

Authors: Sprowl, Jason A., Ciarimboli, Giuliano, Lancaster, Cynthia S., Giovinazzo, Hugh, Gibson, Alice A., Du, Guoqing, Janke, Laura J., Cavaletti, Guido, Shields, Anthony F., Sparreboom, Alex

Source: Proceedings of the National Academy of Sciences of the United States of America, 2013 Jul 01. 110(27), 11199-11204.

Access URL: https://www.jstor.org/stable/42706398

Human OCT2 variant c.808G>T confers protection effect against cisplatin-induced ototoxicity

Authors: Lanvers-Kaminsky, Claudia, Sprowl, Jason A, Malath, Ingrid, Deuster, Dirk, Eveslage, Maria, Schlatter, Eberhard, Mathijssen, Ron HJ, Boos, Joachim, Jürgens, Heribert, am Zehnhoff-Dinnesen, Antionette G, Sparreboom, Alex, Ciarimboli, Giuliano

Source: Pharmacogenomics. 16(4):323-332

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100123906173.0x000001&indx=1&recIds=ETOCvdc_100123906173.0x000001

Contribution of tumoral and host solute carriers to clinical drug response

Authors: Sprowl, Jason A., Mikkelsen, Torben S., Giovinazzo, Hugh, Sparreboom, Alex

Source: In Drug Resistance Updates February-April 2012 15(1-2):5-20

Changes in expression of cell wall turnover genes accompany inhibition of chromosome segregation by bovine protein kinase C α expression in Saccharomyces cerevisiae

Authors: Sprowl, Jason A., Villeneuve, David J., Guo, Baoqing, Young, Andrew J.M., Hembruff, Stacey L., Parissenti, Amadeo M.

Source: In Cell Biology International 2007 31(10):1160-1172

Role of transporters and S100A8/A9 in paclitaxel‐induced peripheral neuropathy

Authors: Li, Yang, Zavorka Thomas, Megan E., Leblanc, Alix F., Huang, Kevin M., Chen, Mingqing, Sprowl, Jason A., Gibson, Alice A., Lustburg, Maryam M., Sparreboom, Alex, Hu, Shuiying

Source: FASEB journal. 34(S1):1-1

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100140403998.0x000001&indx=1&recIds=ETOCvdc_100140403998.0x000001

Differential Contribution of Neuronal Uptake Transporters to Oxaliplatin Peripheral Neurotoxicity

Authors: Huang, Kevin M., Leblanc, Alix F., Alberti, Paola, Sprowl, Jason A., Wang, Jing, Lustberg, Maryam B., Cavaletti, Guido, Hu, Shuiying, Sparreboom, Alex

Source: FASEB journal. 34(S1):1-1

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100140400667.0x000001&indx=1&recIds=ETOCvdc_100140400667.0x000001

Role of aldo-keto reductases and other doxorubicin pharmacokinetic genes in doxorubicin resistance, DNA binding, and subcellular localization

Authors: Heibein Allan D, Guo Baoqing, Sprowl Jason A, MacLean David A, Parissenti Amadeo M

Source: BMC Cancer, Vol 12, Iss 1, p 381 (2012)

Subject Terms: Doxorubicin, Resistance, Gene profiling, PharmGKB, Pharmacokinetics, Aldo-keto reductases, Cytotoxicity, Lysosome, DNA-binding, Drug localization, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.biomedcentral.com/1471-2407/12/381; https://doaj.org/toc/1471-2407

Access URL: https://doaj.org/article/94424e47552e4944adca62a42360b985

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