Engineering Tolerance toward Allogeneic CAR-T Cells by Regulation of MHC Surface Expression with Human Herpes Virus-8 Proteins

Authors: Wang, Xiaomei, Cabrera, Fabricio G., Sharp, Kelly L., Spencer, David M., Foster, Aaron E., Bayle, J. Henri

Source: In Molecular Therapy 3 February 2021 29(2):718-733

Inducible MyD88/CD40 synergizes with IL-15 to enhance antitumor efficacy of CAR-NK cells

Authors: Wang, Xiaomei, Jasinski, Daniel L., Medina, Jan L., Spencer, David M., Foster, Aaron E., Bayle, J. Henri

Source: In Blood Advances 12 May 2020 4(9):1950-1964

Environmental indices for spanner crab (Ranina ranina) catch rates depend on regional oceanographic features

Authors: Spencer, David M., Doubell, Mark J., Brown, Ian W., Redondo Rodriguez, Ana, Lee, Shing Y., Lemckert, Charles J.

Source: In Estuarine, Coastal and Shelf Science 15 November 2019 228

Two-Dimensional Regulation of CAR-T Cell Therapy with Orthogonal Switches

Authors: Duong, MyLinh T. ¹, Collinson-Pautz, Matthew R. ¹, Morschl, Eva ¹, Lu, An ¹, Szymanski, Slawomir P. ¹, Zhang, Ming ¹, Brandt, Mary E. ¹, Chang, Wei-Chun ¹, Sharp, Kelly L. ¹, Toler, Steven M. ¹, Slawin, Kevin M. ¹, Foster, Aaron E. ¹, Spencer, David M. ^{1, ∗}, Bayle, J. Henri ^{1, ∗∗}

Source: In Molecular Therapy - Oncolytics 29 March 2019 12:124-137

Regulated Expansion and Survival of Chimeric Antigen Receptor-Modified T Cells Using Small Molecule-Dependent Inducible MyD88/CD40

Authors: Foster, Aaron E., Mahendravada, Aruna, Shinners, Nicholas P., Chang, Wei-Chun, Crisostomo, Jeannette, Lu, An, Khalil, Mariam, Morschl, Eva, Shaw, Joanne L., Saha, Sunandan, Duong, MyLinh T., Collinson-Pautz, Matthew R., Torres, David L., Rodriguez, Tania, Pentcheva-Hoang, Tsvetelina, Bayle, J. Henri, Slawin, Kevin M., Spencer, David M.

Source: In Molecular Therapy 6 September 2017 25(9):2176-2188

Inducible Dimerization of FGFR1: Development of a Mouse Model to Analyze Progressive Transformation of the Mammary Gland

Authors: Welm, Bryan E., Freeman, Kevin W., Chen, Mercy, Contreras, Alejandro, Spencer, David M., Rosen, Jeffrey M.

Source: The Journal of Cell Biology, 2002 May . 157(4), 703-714.

Access URL: https://www.jstor.org/stable/1621091

Caspase-10 is an Initiator Caspase in Death Receptor Signaling

Authors: Wang, Jin, Chun, Hyung J., Wong, Wilson, Spencer, David M., Lenardo, Michael J.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2001 Nov . 98(24), 13884-13888.

Access URL: https://www.jstor.org/stable/3057189

Synthetic Activation of Caspases: Artificial Death Switches

Authors: MacCorkle, Rebecca A., Freeman, Kevin W., Spencer, David M.

Source: Proceedings of the National Academy of Sciences of the United States of America, 1998 Mar . 95(7), 3655-3660.

Access URL: https://www.jstor.org/stable/44538

A Proliferation Switch for Genetically Modified Cells

Authors: Blau, C. Anthony, Peterson, Kenneth R., Drachman, Jonathan G., Spencer, David M.

Source: Proceedings of the National Academy of Sciences of the United States of America, 1997 Apr 01. 94(7), 3076-3081.

Access URL: https://www.jstor.org/stable/41778

Inducible caspase-9 suicide gene controls adverse effects from alloreplete T cells after haploidentical stem cell transplantation

Authors: Zhou, Xiaoou ^*, Dotti, Gianpietro, Krance, Robert A., Martinez, Caridad A., Naik, Swati, Kamble, Rammurti T., Durett, April G., Dakhova, Olga, Savoldo, Barbara, Di Stasi, Antonio, Spencer, David M., Lin, Yu-Feng, Liu, Hao, Grilley, Bambi J., Gee, Adrian P., Rooney, Cliona M., Heslop, Helen E., Brenner, Malcolm K. ^*

Source: In Blood 25 June 2015 125(26):4103-4113

Tobacco mosaic virus efficiently targets DC uptake, activation and antigen-specific T cell responses in vivo

Authors: Kemnade, Jan Ole, Seethammagari, Mamatha, Collinson-Pautz, Mathew, Kaur, Hardeep, Spencer, David M., McCormick, Alison A.

Source: In Vaccine 16 July 2014 32(33):4228-4233

Long-term outcome after haploidentical stem cell transplant and infusion of T cells expressing the inducible caspase 9 safety transgene

Authors: Zhou, Xiaoou, Di Stasi, Antonio, Tey, Siok-Keen, Krance, Robert A., Martinez, Caridad, Leung, Kathryn S., Durett, April G., Wu, Meng-Fen, Liu, Hao, Leen, Ann M., Savoldo, Barbara, Lin, Yu-Feng, Grilley, Bambi J., Gee, Adrian P., Spencer, David M., Rooney, Cliona M., Heslop, Helen E., Brenner, Malcolm K. ^*, Dotti, Gianpietro ^*

Source: In Blood 19 June 2014 123(25):3895-3905

Development of an inducible caspase-9 safety switch for pluripotent stem cell–based therapies

Authors: Wu, Chuanfeng, Hong, So Gun, Winkler, Thomas, Spencer, David M, Jares, Alexander, Ichwan, Brian, Nicolae, Alina, Guo, Vicky, Larochelle, Andre, Dunbar, Cynthia E

Source: In Molecular Therapy - Methods & Clinical Development 2014 1

Notch and TGFβ Form a Reciprocal Positive Regulatory Loop that Suppresses Murine Prostate Basal Stem/Progenitor Cell Activity

Authors: Valdez, Joseph M., Zhang, Li, Su, Qingtai, Dakhova, Olga, Zhang, Yiqun, Shahi, Payam, Spencer, David M., Creighton, Chad J., Ittmann, Michael M., Xin, Li

Source: In Cell Stem Cell 2 November 2012 11(5):676-688

Off-the-shelf Adenoviral-mediated Immunotherapy via Bicistronic Expression of Tumor Antigen and iMyD88/CD40 Adjuvant

Authors: Kemnade, Jan Ole, Seethammagari, Mamatha, Narayanan, Priya, Levitt, Jonathan M, McCormick, Alison A, Spencer, David M

Source: In Molecular Therapy July 2012 20(7):1462-1471

T cells redirected against CD70 for the immunotherapy of CD70-positive malignancies

Authors: Shaffer, Donald R., Savoldo, Barbara, Yi, Zhongzhen, Chow, Kevin K.H., Kakarla, Sunitha, Spencer, David M., Dotti, Gianpietro, Wu, Meng-Fen, Liu, Hao, Kenney, Shannon, Gottschalk, Stephen

Source: In Blood 21 April 2011 117(16):4304-4314

T Cells Expressing Constitutively Active Akt Resist Multiple Tumor-associated Inhibitory Mechanisms

Authors: Sun, Jiali, Dotti, Gianpietro, Huye, Leslie E, Foster, Aaron E, Savoldo, Barbara, Gramatges, Maria M, Spencer, David M, Rooney, Cliona M

Source: In Molecular Therapy November 2010 18(11):2006-2017

Bottom boundary layer cooling and wind‐driven upwelling enhance the catchability of spanner crab (Ranina ranina) in South‐East Queensland, Australia.

Authors: Spencer, David M.^1,2 david.spencer2@griffithuni.edu.au, Brown, Ian W.³, Doubell, Mark J.², Brown, Christopher J.⁴, Redondo Rodriguez, Ana², Lee, Shing Yip⁵, Zhang, Hong¹, Lemckert, Charles J.⁶

Source: Fisheries Oceanography. May2019, Vol. 28 Issue 3, p317-326. 10p.

Subject Terms: *ECONOMIC efficiency, *FISHERIES, *CRAB populations, *EFFECT of temperature on fishes, *OCEAN bottom temperature, *OCEANOGRAPHY

Controlling Signal Transduction with Synthetic Ligands

Authors: Spencer, David M., Wandless, Thomas J., Schreiber, Stuart L., Crabtree, Gerald R.

Source: Science, 1993 Nov 01. 262(5136), 1019-1024.

Access URL: https://www.jstor.org/stable/2883196

A General Strategy for Producing Conditional Alleles of Src-Like Tyrosine Kinases

Authors: Spencer, David M., Graef, Isabella, Austin, David J., Schreiber, Stuart L., Crabtree, Gerald R.

Source: Proceedings of the National Academy of Sciences of the United States of America, 1995 Oct 01. 92(21), 9805-9809.

Access URL: https://www.jstor.org/stable/2368565