A tetravalent nanovaccine that inhibits growth of HPV-associated head and neck carcinoma via dendritic and T cell activation

Authors: Josi, Romano, Speiser, Daniel E., de Brot, Simone, Vogt, Anne-Cathrine, Sevick-Muraca, Eva M., Tolstonog, Genrich V., Bachmann, Martin F., Mohsen, Mona O.

Source: In iScience 19 April 2024 27(4)

TCR sequencing and cloning methods for repertoire analysis and isolation of tumor-reactive TCRs

Authors: Genolet, Raphael, Bobisse, Sara, Chiffelle, Johanna, Arnaud, Marion, Petremand, Rémy, Queiroz, Lise, Michel, Alexandra, Reichenbach, Patrick, Cesbron, Julien, Auger, Aymeric, Baumgaertner, Petra, Guillaume, Philippe, Schmidt, Julien, Irving, Melita, Kandalaft, Lana E., Speiser, Daniel E., Coukos, George, Harari, Alexandre

Source: In Cell Reports Methods 24 April 2023 3(4)

Peroxynitrite in the tumor microenvironment changes the profile of antigens allowing escape from cancer immunotherapy

Authors: Tcyganov, Evgenii N., Sanseviero, Emilio, Marvel, Douglas, Beer, Thomas, Tang, Hsin-Yao, Hembach, Peter, Speicher, David W., Zhang, Qianfei, Donthireddy, Laxminarasimha R., Mostafa, Ali, Tsyganova, Sabina, Pisarev, Vladimir, Laufer, Terri, Ignatov, Dmitriy, Ferrone, Soldano, Meyer, Christiane, Maby-El Hajjami, Hélène, Speiser, Daniel E., Altiok, Sooner, Antonia, Scott, Xu, Xiaowei, Xu, Wei, Zheng, Cathy, Schuchter, Lynn M., Amaravadi, Ravi K., Mitchell, Tara C., Karakousis, Giorgos C., Yuan, Zhe, Montaner, Luis J., Celis, Esteban, Gabrilovich, Dmitry I.

Source: In Cancer Cell 10 October 2022 40(10):1173-1189

Shared acute phase traits in effector and memory human CD8 T cells

Authors: Fuertes Marraco, Silvia A., Alpern, Daniel, Lofek, Sébastien, Lourenco, Joao, Bovay, Amandine, Maby-El Hajjami, Hélène, Delorenzi, Mauro, Deplancke, Bart, Speiser, Daniel E.

Source: In Current Research in Immunology 2022 3:1-12

Prediction of neo-epitope immunogenicity reveals TCR recognition determinants and provides insight into immunoediting

Authors: Schmidt, Julien, Smith, Angela R., Magnin, Morgane, Racle, Julien, Devlin, Jason R., Bobisse, Sara, Cesbron, Julien, Bonnet, Victor, Carmona, Santiago J., Huber, Florian, Ciriello, Giovanni, Speiser, Daniel E., Bassani-Sternberg, Michal, Coukos, George, Baker, Brian M., Harari, Alexandre, Gfeller, David

Source: In Cell Reports Medicine 16 February 2021 2(2)

Lymphatic-derived oxysterols promote anti-tumor immunity and response to immunotherapy in melanoma.

Authors: Sun, Mengzhu, Garnier, Laure, Chevalier, Romane, Roumain, Martin, Wang, Chen, Angelillo, Julien, Montorfani, Julien, Pick, Robert, Brighouse, Dale, Fournier, Nadine, Tarussio, David, Tissot, Stéphanie, Lobaccaro, Jean-Marc, Petrova, Tatiana V., Jandus, Camilla, Speiser, Daniel E., Kopf, Manfred, Pot, Caroline, Scheiermann, Christoph, Homicsko, Krisztian

Source: Nature Communications; 2/1/2025, Vol. 16 Issue 1, p1-22, 22p

Subject Terms: MEDICAL sciences, TREATMENT effectiveness, MYELOID cells, CELL physiology, LIPID metabolism

Central memory CD8+ T cells derive from stem-like Tcf7hi effector cells in the absence of cytotoxic differentiation

Authors: Pais Ferreira, Daniela, Silva, Joana Gomes, Wyss, Tania, Fuertes Marraco, Silvia A., Scarpellino, Léonardo, Charmoy, Mélanie, Maas, Roeltje, Siddiqui, Imran, Tang, Li, Joyce, Johanna A., Delorenzi, Mauro, Luther, Sanjiv A., Speiser, Daniel E., Held, Werner

Source: In Immunity 17 November 2020 53(5):985-1000

Conserved Interferon-γ Signaling Drives Clinical Response to Immune Checkpoint Blockade Therapy in Melanoma

Authors: Grasso, Catherine S., Tsoi, Jennifer, Onyshchenko, Mykola, Abril-Rodriguez, Gabriel, Ross-Macdonald, Petra, Wind-Rotolo, Megan, Champhekar, Ameya, Medina, Egmidio, Torrejon, Davis Y., Shin, Daniel Sanghoon, Tran, Phuong, Kim, Yeon Joo, Puig-Saus, Cristina, Campbell, Katie, Vega-Crespo, Agustin, Quist, Michael, Martignier, Christophe, Luke, Jason J., Wolchok, Jedd D., Johnson, Douglas B., Chmielowski, Bartosz, Hodi, F. Stephen, Bhatia, Shailender, Sharfman, William, Urba, Walter J., Slingluff, Craig L., Jr., Diab, Adi, Haanen, John B.A.G., Algarra, Salvador Martin, Pardoll, Drew M., Anagnostou, Valsamo, Topalian, Suzanne L., Velculescu, Victor E., Speiser, Daniel E., Kalbasi, Anusha, Ribas, Antoni

Source: In Cancer Cell 12 October 2020 38(4):500-515

Identification of a superagonist variant of the immunodominant Yellow fever virus epitope NS4b 214-222 by combinatorial peptide library screening

Authors: Bovay, Amandine, Zoete, Vincent, Rizkallah, Pierre J., Beck, Konrad, Delbreil, Philippe, Speiser, Daniel E., Cole, David K., Fuertes Marraco, Silvia A. ^*

Source: In Molecular Immunology September 2020 125:43-50

Intratumoral Tcf1+PD-1+CD8+ T Cells with Stem-like Properties Promote Tumor Control in Response to Vaccination and Checkpoint Blockade Immunotherapy

Authors: Siddiqui, Imran, Schaeuble, Karin, Chennupati, Vijaykumar, Fuertes Marraco, Silvia A., Calderon-Copete, Sandra, Pais Ferreira, Daniela, Carmona, Santiago J., Scarpellino, Leonardo, Gfeller, David, Pradervand, Sylvain, Luther, Sanjiv A., Speiser, Daniel E., Held, Werner

Source: In Immunity 15 January 2019 50(1):195-211

The C-terminal extension landscape of naturally presented HLA-I ligands

Authors: Guillaume, Philippe, Picaud, Sarah, Baumgaertner, Petra, Montandon, Nicole, Schmidt, Julien, Speiser, Daniel E., Coukos, George, Bassani-Sternberg, Michal, Filippakopoulos, Panagis, Gfeller, David

Source: Proceedings of the National Academy of Sciences of the United States of America, 2018 May . 115(20), 5083-5088.

Access URL: https://www.jstor.org/stable/26509487

Efficient T Cell Repertoire Selection in Tetraparental Chimeric Mice Independent of Thymic Epithelial MHC

Authors: Martinic, Marianne M., Rülicke, Thomas, Althage, Alana, Odermatt, Bernhard, Höchli, Matthias, Lamarre, Alain, Dumrese, Tilman, Speiser, Daniel E., Kyburz, Diego, Hengartner, Hans, Zinkernagel, Rolf M.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2003 Feb . 100(4), 1861-1866.

Access URL: https://www.jstor.org/stable/3138450

A reporter virus particle seroneutralization assay for tick‐borne encephalitis virus overcomes ELISA limitations.

Authors: Ackermann‐Gäumann, Rahel, Dentand, Alexis, Lienhard, Reto, Saeed, Mohsan, Speiser, Daniel E., MacDonald, Margaret R., Coste, Alix T., Cagno, Valeria

Source: Journal of Medical Virology; Aug2024, Vol. 96 Issue 8, p1-14, 14p

Subject Terms: JAPANESE encephalitis viruses, WEST Nile virus, ENCEPHALITIS viruses, DENGUE viruses, ZIKA virus

From T cell “exhaustion” to anti-cancer immunity

Authors: Verdeil, Grégory, Fuertes Marraco, Silvia A., Murray, Timothy, Speiser, Daniel E.

Source: In BBA - Reviews on Cancer January 2016 1865(1):49-57

Immunopeptidomics-based identification of naturally presented non-canonical circRNA-derived peptides.

Authors: Ferreira, Humberto J., Stevenson, Brian J., HuiSong Pak, Fengchao Yu, Oliveira, Jessica Almeida, Huber, Florian, Taillandier-Coindard, Marie, Michaux, Justine, Ricart-Altimiras, Emma, Kraemer, Anne I., Kandalaft, Lana E., Speiser, Daniel E., Nesvizhskii, Alexey I., Müller, Markus, Bassani-Sternberg, Michal

Source: Nature Communications; 3/15/2024, Vol. 15 Issue 1, p1-18, 18p

STING activation of tumor endothelial cells initiates spontaneous and therapeutic antitumor immunity

Authors: Demaria, Olivier, De Gassart, Aude, Coso, Sanja, Gestermann, Nicolas, Di Domizio, Jeremy, Flatz, Lukas, Gaide, Olivier, Michielin, Olivier, Hwu, Patrick, Petrova, Tatiana V., Martinon, Fabio, Modlin, Robert L., Speiser, Daniel E., Gilliet, Michel

Source: Proceedings of the National Academy of Sciences of the United States of America, 2015 Dec . 112(50), 15408-15413.

Access URL: https://www.jstor.org/stable/26466609

Ipilimumab-dependent cell-mediated cytotoxicity of regulatory T cells ex vivo by nonclassical monocytes in melanoma patients

Authors: Romano, Emanuela, Kusio-Kobialka, Monika, Foukas, Periklis G., Baumgaertner, Petra, Meyer, Christiane, Ballabeni, Pierluigi, Michielin, Olivier, Weide, Benjamin, Romero, Pedro, Speiser, Daniel E.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2015 May 01. 112(19), 6140-6145.

Access URL: https://www.jstor.org/stable/26462754

Successful Allergen-Specific Immunotherapy: Induction of Unresponsiveness by 'Vaccination'.

Authors: Bachmann, Martin F., Vogel, Monique, Speiser, Daniel E.

Source: Vaccines; Dec2023, Vol. 11 Issue 12, p1852, 4p

Subject Terms: VACCINATION, IMMUNOTHERAPY, PRAXIS (Process), IMMUNOGLOBULIN G, IMMUNOGLOBULINS

Chapter 42 - Noninfectious Disease Vaccines

Authors: Speiser, Daniel E., El-Turabi, Aadil, Bachmann, Martin F.

Source: In Plotkin's Vaccines Edition: Eighth Edition. 2023:736-746

A phase I dose-escalation study of the immunocytokine EMD 521873 (Selectikine) in patients with advanced solid tumours

Authors: Gillessen, Silke, Gnad-Vogt, Ulrike S., Gallerani, Elisa, Beck, Joachim, Sessa, Cristiana, Omlin, Aurelius, Mattiacci, Maria R., Liedert, Bernd, Kramer, Daniel, Laurent, Julien, Speiser, Daniel E., Stupp, Roger

Source: In European Journal of Cancer January 2013 49(1):35-44