Synthesis and Evaluation of ePSMA-DM1: A New Theranostic Small-Molecule Drug Conjugate (T-SMDC) for Prostate Cancer.

Authors: Murce, Erika^1,2 (AUTHOR) e.murcesilva@erasmusmc.nl, Spaan, Evelien^1,2 (AUTHOR) e.spaan@erasmusmc.nl, Beekman, Savanne^1,2 (AUTHOR) s.beekman@erasmusmc.nl, van den Brink, Lilian^1,2 (AUTHOR) l.vandenbrink@erasmusmc.nl, Handula, Maryana^1,2 (AUTHOR) m.handula@erasmusmc.nl, Stuurman, Debra^1,2 (AUTHOR) d.stuurman@erasmusmc.nl, de Ridder, Corrina^1,2 (AUTHOR) c.deridder@erasmusmc.nl, Dalm, Simone U.^1,2 (AUTHOR) s.dalm@erasmusmc.nl, Seimbille, Yann^1,2,3 (AUTHOR) y.seimbille@erasmusmc.nl

Source: Pharmaceuticals (14248247). Aug2023, Vol. 16 Issue 8, p1072. 19p.

Subject Terms: *PROSTATE cancer, *COMPUTED tomography, *RADIOCHEMICAL purification, *ANDROGEN receptors, *DRUGS, *DIAGNOSTIC imaging, *ANDROGENS

O-76 - Preclinical evaluation of ePSMA-DM1: a PSMA-targeting theranostic small molecule drug conjugate

Authors: Seimbille, Yann, Murce, Erika, Spaan, Evelien, Beekman, Savanne, Handula, Maryana, de Ridder, Corrina, Stuurman, Debra

Source: In Nuclear Medicine and Biology November-December 2023 126-127 Supplement

Synthesis of a PSMA-targeting ligand with an optimized linker for imaging and treatment of prostate cancer

Authors: Murce, Erika, Spaan, Evelien, Seimbille, Yann

Source: Nuclear medicine and biology. 108(S):S206-S207

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100163690042.0x000001&indx=1&recIds=ETOCvdc_100163690042.0x000001

Preclinical Evaluation of a PSMA-Targeting Homodimer with an Optimized Linker for Imaging of Prostate Cancer.

Authors: Murce, Erika, Beekman, Savanne, Spaan, Evelien, Handula, Maryana, Stuurman, Debra, de Ridder, Corrina, Seimbille, Yann

Source: Molecules; May2023, Vol. 28 Issue 10, p4022, 20p

Subject Terms: PROSTATE cancer, CANCER diagnosis, KIDNEY tumors, SINGLE-photon emission computed tomography

P-288 - Synthesis of a PSMA-targeting ligand with an optimized linker for imaging and treatment of prostate cancer

Authors: Murce, Erika, Spaan, Evelien, Seimbille, Yann

Source: In Nuclear Medicine and Biology May-June 2022 108-109 Supplement:S206-S207