Real-World Treatment Patterns and Clinical Outcomes in Patients With Locally Advanced or Metastatic Urothelial Carcinoma by Eligibility for Maintenance Avelumab

Authors: Morgans, Alicia K. ^{1, ⁎}, Sonpavde, Guru P. ², Shih, Vanessa ³, Wright, Phoebe ³, Hepp, Zsolt ³, Willmon, Candice L. ³, Chang, Nancy N. ³, Mucha, Lisa ⁴, Naga, Sai Sriteja Boppudi ⁵, Powles, Thomas ⁶

Source: In Clinical Genitourinary Cancer February 2025 23(1)

Avelumab First-Line Maintenance for Locally Advanced or Metastatic Urothelial Carcinoma: Results From the Real-World US PATRIOT-II Study

Authors: Grivas, Petros, Barata, Pedro, Moon, Helen, Gupta, Shilpa, Hutson, Thomas ^*, Sternberg, Cora N., Brown, Jason R., Dave, Vaidehi, Downey, Chad, Shillington, Alicia C., Katzenstein, Howard M. ^*, Kirker, Melissa, Hanson, Sarah, Liu, Frank X. ^*, Morris, Valerie, Bhanegaonkar, Abhijeet, Sonpavde, Guru P.

Source: In Clinical Genitourinary Cancer December 2024 22(6)

Impact of Angiotensin Converting Enzyme Inhibitors on Pathologic Complete Response With Neoadjuvant Chemotherapy for Muscle Invasive Bladder Cancer

Authors: Skelton, William Paul, IV ^{1, 2}, Masur, Jack ¹, Thomas, Jonathan ³, Fallah, Parvaneh ⁴, Jain, Rohit K. ², Ravi, Praful ³, Mantia, Charlene ³, McGregor, Bradley Alexander ³, Nuzzo, Pier Vitale ³, Adib, Elio ³, Zarif, Talal El ³, Preston, Mark A. ⁵, Clinton, Timothy Nguyen ⁵, Li, Roger ², Steele, Graeme S. ⁵, Kassouf, Wassim ⁴, Freeman, Dory ³, Pond, Gregory Russell ⁶, Jain, Rakesh K. ⁷, Sonpavde, Guru P. ^{3, 8, ⁎}

Source: In Clinical Genitourinary Cancer October 2024 22(5)

Real-World Multicenter Study of PD-1 Blockade in HIV-Associated Classical Hodgkin Lymphoma Across the United States

Authors: Lurain, Kathryn, Zarif, Talal El, Ramaswami, Ramya, Nassar, Amin H., Adib, Elio, Abdel-Wahab, Noha, Chintapally, Nikita, Drolen, Claire E., Feldman, Tatyana, Haykal, Tarek, Nebhan, Caroline A., Thiruvengadam, Swetha Kambhampati, Li, Mingjia, Mittra, Arjun, Lorentsen, Michael, Kim, Chul, Drakaki, Alexandra, Morse, Michael, Johnson, Douglas B., Mangla, Ankit, Dittus, Christopher, Ravi, Praful, Baiocchi, Robert A., Chiao, Elizabeth Y., Rubinstein, Paul G., Yellapragada, Sarvari V., LaCasce, Ann S., Sonpavde, Guru P., Naqash, Abdul Rafeh, Herrera, Alex F.

Source: In Clinical Lymphoma, Myeloma and Leukemia August 2024 24(8):523-530

Health-related Quality of Life in Patients with Previously Treated Advanced Urothelial Carcinoma from EV-301: A Phase 3 Trial of Enfortumab Vedotin Versus Chemotherapy

Authors: Rosenberg, Jonathan E., Mamtani, Ronac, Sonpavde, Guru P., Loriot, Yohann, Duran, Ignacio, Lee, Jae-Lyun, Matsubara, Nobuaki, Vulsteke, Christof, Castellano, Daniel, Sridhar, Srikala S., Pappot, Helle, Gurney, Howard, Bedke, Jens, van der Heijden, Michiel S., Galli, Luca, Keam, Bhumsuk, Masumori, Naoya, Meran, Johannes, O'Donnell, Peter H., Park, Se Hoon, Grande, Enrique, Sengeløv, Lisa, Uemura, Hiroji, Skaltsa, Konstantina, Campbell, Mary, Matsangou, Maria, Wu, Chunzhang, Hepp, Zsolt, McKay, Caroline, Powles, Thomas, Petrylak, Daniel P.

Source: In European Urology June 2024 85(6):574-585

Circulating tumor DNA as a Predictive and Prognostic Biomarker in the Perioperative Treatment of Muscle-invasive Bladder Cancer: A Systematic Review

Authors: Crupi, Emanuele, de Padua, Tiago Costa, Marandino, Laura, Raggi, Daniele, Dyrskjøt, Lars, Spiess, Philippe E., Sonpavde, Guru P., Kamat, Ashish M., Necchi, Andrea

Source: In European Urology Oncology February 2024 7(1):44-52

Safety and Activity of Immune Checkpoint Inhibitors in People Living With HIV and Cancer: A Real-World Report From the Cancer Therapy Using Checkpoint Inhibitors in People Living With HIV-International (CATCH-IT) Consortium

Authors: El Zarif, Talal, Nassar, Amin H., Adib, Elio, Fitzgerald, Bailey G., Huang, Jiaming, Mouhieddine, Tarek H., Rubinstein, Paul G., Nonato, Taylor, McKay, Rana R., Li, Mingjia, Mittra, Arjun, Owen, Dwight H., Baiocchi, Robert A., Lorentsen, Michael, Dittus, Christopher, Dizman, Nazli, Falohun, Adewunmi, Abdel-Wahab, Noha, Diab, Adi, Bankapur, Anand, Reed, Alexandra, Kim, Chul, Arora, Aakriti, Shah, Neil J., El-Am, Edward, Kozaily, Elie, Abdallah, Wassim, Al-Hader, Ahmad, Abu Ghazal, Batool, Saeed, Anwaar, Drolen, Claire, Lechner, Melissa G., Drakaki, Alexandra, Baena, Javier, Nebhan, Caroline A., Haykal, Tarek, Morse, Michael A., Cortellini, Alessio, Pinato, David J., Dalla Pria, Alessia, Hall, Evan, Bakalov, Veli, Bahary, Nathan, Rajkumar, Aarthi, Mangla, Ankit, Shah, Vishal, Singh, Parminder, Aboubakar Nana, Frank, Lopetegui-Lia, Nerea, Dima, Danai, Dobbs, Ryan W., Funchain, Pauline, Saleem, Rabia, Woodford, Rachel, Long, Georgina V., Menzies, Alexander M., Genova, Carlo, Barletta, Giulia, Puri, Sonam, Florou, Vaia, Idossa, Dame, Saponara, Maristella, Queirolo, Paola, Lamberti, Giuseppe, Addeo, Alfredo, Bersanelli, Melissa, Freeman, Dory, Xie, Wanling, Reid, Erin G., Chiao, Elizabeth Y., Sharon, Elad, Johnson, Douglas B., Ramaswami, Ramya, Bower, Mark, Emu, Brinda, Marron, Thomas U., Choueiri, Toni K., Baden, Lindsey R., Lurain, Kathryn, Sonpavde, Guru P., Naqash, Abdul Rafeh

Source: Journal of clinical oncology. 41(21):3712-3723

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100193353001.0x000001&indx=1&recIds=ETOCvdc_100193353001.0x000001

Efficacy of enfortumab vedotin in advanced urothelial cancer: Analysis from the Urothelial Cancer Network to Investigate Therapeutic Experiences (UNITE) study

Authors: Koshkin, Vadim S., Henderson, Nicholas, James, Marihella, Natesan, Divya, Freeman, Dory, Nizam, Amanda, Su, Christopher T., Khaki, Ali Raza, Osterman, Chelsea K., Glover, Michael J., Chiang, Ryan, Makrakis, Dimitrios, Talukder, Rafee, Lemke, Emily, Olsen, T. Anders, Jain, Jayanshu, Jang, Albert, Ali, Alicia, Jindal, Tanya, Chou, Jonathan, Friedlander, Terence W., Hoimes, Christopher, Basu, Arnab, Zakharia, Yousef, Barata, Pedro C., Bilen, Mehmet A., Emamekhoo, Hamid, Davis, Nancy B., Shah, Sumit A., Milowsky, Matthew I., Gupta, Shilpa, Campbell, Matthew T., Grivas, Petros, Sonpavde, Guru P., Kilari, Deepak, Alva, Ajjai S.

Source: Cancer. 128(6):1194-1205

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100142031419.0x000001&indx=1&recIds=ETOCvdc_100142031419.0x000001

FGFR2/3 genomic alterations and response to Enfortumab Vedotin in metastatic urothelial carcinoma

Authors: Adib, Elio, El‐Zarif, Talal, Jain, Rohit K., Skelton, William P., Freeman, Dory, Curran, Catherine, Akl, Elie W., Nassar, Amin H., Ravi, Praful, Mantia, Charlene, Kwiatkowski, David J., Choueiri, Toni K., Sonpavde, Guru P.

Source: BJUI Compass. 3(2):169-172

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100141115912.0x000001&indx=1&recIds=ETOCvdc_100141115912.0x000001

A phase II clinical trial of neoadjuvant sasanlimab and stereotactic body radiation therapy as an in situ vaccine for cisplatin-ineligible MIBC: the RAD VACCINE MIBC trial

Authors: Satkunasivam, Raj, Lim, Kelvin, Teh, Bin S, Guzman, Jonathan, Zhang, Jun, Farach, Andrew, Chen, Shu-Hsia, Wallis, Christopher JD, Efstathiou, Eleni, Esnaola, Nestor F, Sonpavde, Guru P

Source: Future oncology. 18(25):2771-2781

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100191695497.0x000001&indx=1&recIds=ETOCvdc_100191695497.0x000001

Clinical outcomes and patterns of population‐based management of urachal carcinoma of the bladder: An analysis of the National Cancer Database

Authors: Dursun, Furkan, Lim, Kelvin, Svatek, Robert S., Xu, Jiaqiong, El‐Zaatari, Ziad M., Wenker, Evan P., Klaassen, Zachary W., Mansour, Ahmed M., Muhammad, Taliah, Efstathiou, Eleni, Sonpavde, Guru P., Wallis, Christopher J. D., Satkunasivam, Raj

Source: Cancer medicine. 11(22):4273-4282

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100165474986.0x000001&indx=1&recIds=ETOCvdc_100165474986.0x000001

Therapy for Muscle-Invasive Urothelial Carcinoma: Controversies and Dilemmas

Authors: Sonpavde, Guru P., Mouw, Kent W., Mossanen, Matthew

Source: Journal of clinical oncology. 40(12):1275-1280

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100152856664.0x000001&indx=1&recIds=ETOCvdc_100152856664.0x000001

Primary results of STRONG: An open-label, multicenter, phase 3b study of fixed-dose durvalumab monotherapy in previously treated patients with urinary tract carcinoma

Authors: Sonpavde, Guru P., Sternberg, Cora N., Loriot, Yohann, Marabelle, Aurelien, Lee, Jae Lyun, Fléchon, Aude, Roubaud, Guilhem, Pouessel, Damien, Zagonel, Vittorina, Calabro, Fabio, Banna, Giuseppe L., Shin, Sang Joon, Vera-Badillo, Francisco E., Powles, Thomas, Hellmis, Eva, Miranda, Paulo A.P., Lima, Ana Rita, Emeribe, Ugochi, Oh, Sun Min, Hotte, Sebastien J.

Source: European journal of cancer. 163:55-65

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100155860480.0x000001&indx=1&recIds=ETOCvdc_100155860480.0x000001

Disparities in Representation of Women, Older Adults, and Racial/Ethnic Minorities in Immune Checkpoint Inhibitor Trials

Authors: Riaz, Irbaz B., Islam, Mahnoor, Khan, Ahsan Masood, Naqvi, Syed Arsalan Ahmed, Siddiqi, Rabbia, Khakwani, Kaneez Zahra Rubab, Asghar, Noureen, Ikram, Waleed, Hussain, Syed A., Singh, Parminder, Warner, Jeremy L., Sonpavde, Guru P., Odedina, Folakemi T., Kehl, Kenneth L., Duma, Narjust, Bryce, Alan H.

Source: In The American Journal of Medicine August 2022 135(8):984-992

Spatial transcriptomic analysis of tumor tissue from patients with metastatic urothelial carcinoma (mUC) receiving ipilimumab (IPI) plus nivolumab (Nivo) combined with sacituzumab govitecan (SG).

Authors: Ong, Faustine, Xu, Jin, Zhang, Yonghong, Chatwal, Monica Sheila, Chadha, Jus, Kim, Youngchul, Segura, Carlos Moran, Yoder, Sean J., Villeta-Astacio, Gabriela, Marchion, Douglas C., Dhillon, Jasreman, Zhang, Jingsong, Guevara, Jose Alejandro, Wang, Xuefeng, Sonpavde, Guru P., Jain, Rohit K.

Source: Journal of Clinical Oncology; 2/20/2025 Supplement 5, Vol. 43, p863-863, 242p

ETCTN 10483: Phase Ib trial of erdafitinib (E) combined with enfortumab vedotin (EV) following platinum and PD-1/L1 inhibitors for metastatic urothelial carcinoma (mUC) with FGFR3/2 genetic alterations (GAs).

Authors: Jain, Rohit K., Ong, Faustine, Faltas, Bishoy Morris, Tagawa, Scott T., Jiang, Di Maria, Heiligh, Jazlyn, Naqvi, Syeda Mahrukh Hussnain, Kim, Youngchul, Pelosof, Lorraine Cheryl, Yang, Yuanquan, Graham, Laura, Arafat, Waddah, Synold, Timothy Walter, Chatwal, Monica Sheila, Zhang, Jingsong, Chadha, Jus, Sonpavde, Guru P.

Source: Journal of Clinical Oncology; 2/20/2025 Supplement 5, Vol. 43, p808-808, 242p

Novel urine-enriched RNA panel (EPCAM, TTC3, H4C5) to detect prostate cancer and differentiate it from benign prostatic disease.

Authors: Perera, Ranjan Joseph, Yuan, Menglang, Moschovas, Marcio, Perera, Roshane, Amankwah, Ernest, Lee, Bongyong, Sonpavde, Guru P., Patel, Vipul, Pavlovich, Christian P., Joshi, Kandarp

Source: Journal of Clinical Oncology; 2/20/2025 Supplement 5, Vol. 43, p31-31, 288p

Preclinical Models for Bladder Cancer Research

Authors: Zhu, Shaoming, Zhu, Zheng, Ma, Ai-Hong, Sonpavde, Guru P., Cheng, Fan, Pan, Chong-xian

Source: In Hematology/Oncology Clinics of North America June 2021 35(3):613-632

Trans-ethnic variation in germline variants of patients with renal cell carcinoma

Authors: Abou Alaiwi, Sarah, Nassar, Amin H., Adib, Elio, Groha, Stefan M., Akl, Elie W., McGregor, Bradley A., Esplin, Edward D., Yang, Shan, Hatchell, Kathryn, Fusaro, Vincent, Nielsen, Sarah, Kwiatkowski, David J., Sonpavde, Guru P., Pomerantz, Mark, Garber, Judy E., Freedman, Matthew L., Rana, Huma Q., Gusev, Alexander, Choueiri, Toni K.

Source: In Cell Reports 30 March 2021 34(13)

Contemporary Treatment Patterns for Non-muscle-invasive Bladder Cancer: Has the Use of Radical Cystectomy Changed in the BCG Shortage Era?

Authors: Tully, Karl H., Cole, Alexander P., Krimphove, Marieke J., Friedlander, David F., Mossanen, Matthew, Herzog, Peter, Noldus, Joachim, Sonpavde, Guru P., Trinh, Quoc-Dien

Source: In Urology January 2021 147:199-204