SOD2 orchestrates redox homeostasis in intervertebral discs: A novel insight into oxidative stress-mediated degeneration and therapeutic potential

Authors: Tamagawa, Shota, Sakai, Daisuke, Nojiri, Hidetoshi, Nakamura, Yoshihiko, Warita, Takayuki, Matsushita, Erika, Schol, Jordy, Soma, Hazuki, Ogasawara, Shota, Munesada, Daiki, Koike, Masato, Shimizu, Takahiko, Sato, Masato, Ishijima, Muneaki, Watanabe, Masahiko

Source: In Redox Biology May 2024 71

Recombinant Laminin-511 Fragment (iMatrix-511) Coating Supports Maintenance of Human Nucleus Pulposus Progenitor Cells In Vitro.

Authors: Soma, Hazuki^1,2 (AUTHOR) soma.hazuki@tunzpharma.co.jp, Sakai, Daisuke^1,3 (AUTHOR) daisakai@is.icc.u-tokai.ac.jp, Nakamura, Yoshihiko¹ (AUTHOR) takayuki.warita@tunzpharma.co.jp, Tamagawa, Shota⁴ (AUTHOR) s-tamagawa@juntendo.ac.jp, Warita, Takayuki^1,2 (AUTHOR) schol.jordy@gmail.com, Schol, Jordy^1,3 (AUTHOR) me091130@tsc.u-tokai.ac.jp, Matsushita, Erika¹ (AUTHOR) sato-m@is.icc.u-tokai.ac.jp, Naiki, Mitsuru² (AUTHOR), Sato, Masato^1,3 (AUTHOR) masahiko@is.icc.u-tokai.ac.jp, Watanabe, Masahiko^1,3 (AUTHOR)

Source: International Journal of Molecular Sciences. Dec2023, Vol. 24 Issue 23, p16713. 16p.

Subject Terms: *NUCLEUS pulposus, *PROGENITOR cells, *INTERVERTEBRAL disk, *EXTRACELLULAR matrix, *INDUSTRIAL capacity

N‐acetylcysteine attenuates oxidative stress‐mediated cell viability loss induced by dimethyl sulfoxide in cryopreservation of human nucleus pulposus cells: A potential solution for mass production

Authors: Shota Tamagawa, Daisuke Sakai, Jordy Schol, Kosuke Sako, Yoshihiko Nakamura, Erika Matsushita, Takayuki Warita, Soma Hazuki, Hidetoshi Nojiri, Masato Sato, Muneaki Ishijima, Masahiko Watanabe

Source: JOR Spine, Vol 5, Iss 4, Pp n/a-n/a (2022)

Subject Terms: cell therapy, cryopreservation, dimethyl sulfoxide, discogenic cell, intervertebral disc degeneration, N‐acetylcysteine, Orthopedic surgery, RD701-811

File Description: electronic resource

Relation: https://doaj.org/toc/2572-1143

Access URL: https://doaj.org/article/ad7e3b2deb4b4def8c1e3fdd25886024

Alginate vs. Hyaluronic Acid as Carriers for Nucleus Pulposus Cells: A Study on Regenerative Outcomes in Disc Degeneration.

Authors: Ogasawara, Shota, Schol, Jordy, Sakai, Daisuke, Warita, Takayuki, Susumu, Takano, Nakamura, Yoshihiko, Sako, Kosuke, Tamagawa, Shota, Matsushita, Erika, Soma, Hazuki, Sato, Masato, Watanabe, Masahiko

Source: Cells (2073-4409); Dec2024, Vol. 13 Issue 23, p1984, 20p

Subject Terms: CHRONIC pain, NUCLEUS pulposus, INTERVERTEBRAL disk, CELL transplantation, HYALURONIC acid

ISSLS PRIZE in Basic Science 2024: superiority of nucleus pulposus cell- versus mesenchymal stromal cell-derived extracellular vesicles in attenuating disc degeneration and alleviating pain.

Authors: Ambrosio, Luca, Schol, Jordy, Ruiz-Fernandez, Clara, Tamagawa, Shota, Soma, Hazuki, Tilotta, Veronica, Di Giacomo, Giuseppina, Cicione, Claudia, Nakayama, Shunya, Kamiya, Kosuke, Papalia, Rocco, Sato, Masato, Vadalà, Gianluca, Watanabe, Masahiko, Denaro, Vincenzo, Sakai, Daisuke

Source: European Spine Journal; May2024, Vol. 33 Issue 5, p1713-1727, 15p

Subject Terms: NUCLEUS pulposus, EXTRACELLULAR vesicles, INTERVERTEBRAL disk, LABORATORY rats, CELLULAR aging, CELL communication, IMMUNOSENESCENCE, LEG pain