Mechanism-free repurposing of drugs for C9orf72-related ALS/FTD using large-scale genomic data

Authors: Baloh, Robert H., Bowser, Robert, Brady, Christopher B., Brice, Alexis, Broach, James, Camu, William, Chia, Ruth, Chio, Adriano, Cooper-Knock, John, Cusi, Daniele, Ding, Jinhui, Drepper, Carsten, Drory, Vivian E., Dunckley, Travis L., Feldman, Eva, Floeter, Mary Kay, Fratta, Pietro, Gerhard, Glenn, Gibbs, J. Raphael, Gibson, Summer B., Glass, Jonathan D., Goutman, Stephen A., Hardy, John, Harms, Matthew B., Heiman-Patterson, Terry D., Jansson, Lilja, Kirby, Janine, Laaksovirta, Hannu, Landers, John E., Landi, Francesco, Le Ber, Isabelle, Lumbroso, Serge, Guissart, Claire, MacGowan, Daniel JL., Maragakis, Nicholas J., Mora, Gabriele, Mouzat, Kevin, Myllykangas, Liisa, Orrell, Richard W., Ostrow, Lyle W., Pickering-Brown, Stuart, Pioro, Erik P., Pulst, Stefan M., Ravits, John M., Renton, Alan E., Robberecht, Wim, Rogaeva, Ekaterina, Rothstein, Jeffrey D., Salvi, Erika, Scholz, Sonja W., Sendtner, Michael, Shaw, Pamela J., Sidle, Katie C., Simmons, Zachary, Stone, David J., Tienari, Pentti J., Traynor, Bryan J., Trojanowski, John Q., Troncoso, Juan C., Valori, Miko, Van Damme, Philip, Van Deerlin, Vivianna M., Van Den Bosch, Ludo, Zinman, Lorne, Angelocola, Stefania M., Ausiello, Francesco P., Barberis, Marco, Bartolomei, Ilaria, Battistini, Stefania, Bersano, Enrica, Bisogni, Giulia, Borghero, Giuseppe, Brunetti, Maura, Cabona, Corrado, Calvo, Andrea, Canale, Fabrizio, Canosa, Antonio, Cantisani, Teresa A., Capasso, Margherita, Caponnetto, Claudia, Cardinali, Patrizio, Carrera, Paola, Casale, Federico, Colletti, Tiziana, Conforti, Francesca L., Conte, Amelia, Conti, Elisa, Corbo, Massimo, Cuccu, Stefania, Bella, Eleonora Dalla, D'Errico, Eustachio, DeMarco, Giovanni, Dubbioso, Raffaele, Ferrarese, Carlo, Ferraro, Pilar M., Filippi, Massimo, Fini, Nicola, Floris, Gianluca, Fuda, Giuseppe, Gallone, Salvatore, Gianferrari, Giulia, Giannini, Fabio, Grassano, Maurizio, Greco, Lucia, Iazzolino, Barbara, Introna, Alessandro, La Bella, Vincenzo, Lattante, Serena, Lauria, Giuseppe, Liguori, Rocco, Logroscino, Giancarlo, Logullo, Francesco O., Lunetta, Christian, Mandich, Paola, Mandrioli, Jessica, Manera, Umberto, Manganelli, Fiore, Marangi, Giuseppe, Marinou, Kalliopi, Marrosu, Maria Giovanna, Martinelli, Ilaria, Messina, Sonia, Moglia, Cristina, Monsurrò, Maria Rosaria, Mosca, Lorena, Murru, Maria R., Origone, Paola, Passaniti, Carla, Petrelli, Cristina, Petrucci, Antonio, Pirisi, Angelo, Pozzi, Susanna, Pugliatti, Maura, Quattrini, Angelo, Ricci, Claudia, Riolo, Giulia, Riva, Nilo, Russo, Massimo, Sabatelli, Mario, Salamone, Paolina, Salivetto, Marco, Salvi, Fabrizio, Santarelli, Marialuisa, Sbaiz, Luca, Sideri, Riccardo, Simone, Isabella, Simonini, Cecilia, Spataro, Rossella, Tanel, Raffaella, Tedeschi, Gioacchino, Ticca, Anna, Torriello, Antonella, Tranquilli, Stefania, Tremolizzo, Lucio, Trojsi, Francesca, Vasta, Rosario, Vacchiano, Veria, Vita, Giuseppe, Volanti, Paolo, Zollino, Marcella, Zucchi, Elisabetta, Silani, Vincenzo, Fogh, Isabella, Ticozzi, Nicola, Ratti, Antonia, Tiloca, Cinzia, Peverelli, Silvia, Gellera, Cinzia, Pinter, Giuseppe Lauria, Taroni, Franco, Pensato, Viviana, Castellotti, Barbara, Comi, Giacomo P., Corti, Stefania, Del Bo, Roberto, Cereda, Cristina, Ceroni, Mauro, Gagliardi, Stella, Corrado, Lucia, Mazzini, Letizia, Sorarù, Gianni, Raggi, Flavia, Siciliano, Gabriele, Simoncini, Costanza, Lo Gerfo, Annalisa, Filosto, Massimiliano, Inghilleri, Maurizio, Ferlini, Alessandra, Corcia, Philippe, Couratier, Philippe, Vourc'h, Patrick, Hardiman, Orla, McLaughlin, Russell, Gotkine, Marc, Drory, Vivian, van den Veldink, Jan H., Berg, Leonard H., de Carvalho, Mamede, Mora Pardina, Jesus S., Povedano, Monica, Andersen, Peter, Weber, Markus, Başak, Ayşe Nazlı, Al-Chalabi, Ammar, Shaw, Chris, Morrison, Karen E., Adeleye, Adelani, Alba, Camille, Bacikova, Dagmar, Dalgard, Clifton L., Hupalo, Daniel N., McGrath Martinez, Elisa, Soltis, Anthony R., Sukumar, Gauthaman, Viollet, Coralie, Wilkerson, Matthew D., Saez-Atienzar, Sara ^{1, 2, 80, ∗}, Souza, Cleide dos Santos ^{3, 80}, Beal, Selina N. ³, Lorenzini, Ileana ⁴, Huang, Ruili ⁵, Levy, Jennifer ⁴, Burciu, Camelia ⁴, Jones, Ashley ⁷, Dewan, Ramita ¹, van Vugt, Joke J.F.A. ¹¹, van Rheenen, Wouter ¹¹, Tunca, Ceren ¹², Bayraktar, Elif ¹², Xia, Menghang ⁵, Iacoangeli, Alfredo ^{7, 13, 14}, Shatunov, Aleksey ⁷, Verde, Federico ^{9, 15}, Kenna, Kevin ¹¹, Al Khleifat, Ahmad ⁷, Opie-Martin, Sarah ⁷, Piccinelli, Stefano Cotti ^{18, 19}, Padovani, Alessandro ¹⁹, Galimberti, Daniela ^{34, 35}, Serpente, Maria ³⁴, Fenoglio, Chiara ^{34, 35}, Scarpini, Elio ³⁴, Curtis, Charles J. ^{41, 42}, Lee, Sang Hyuck ^{41, 42}, Chung, Raymond ^{41, 42}, Patel, Hamel ^{13, 42}, Cooper-Knock, Johnathan ⁴⁴, Breen, Gerome ^{41, 42}, Dobson, Richard J.B. ^{45, 46, 47, 48, 49}, van den Berg, Leonard H. ¹¹, D’Alfonso, Sandra ¹⁰, Chandran, Siddharthan ^{58, 59}, Pal, Suvankar ^{58, 60}, Johnson, Kory ⁶², Doucet-O’Hare, Tara ⁶³, Pasternack, Nicholas ⁶⁴, Wang, Tongguang ⁶⁴, Nath, Avindra ⁶⁴, Veldink, Jan H. ¹¹, Chiò, Adriano ^{24, 25, 26}, Sattler, Rita ⁴, Shaw, Christopher E. ^{69, 70, 80}, Ferraiuolo, Laura ^{71, 80}

Source: In Cell Genomics 13 November 2024 4(11)

Genome-wide structural variant analysis identifies risk loci for non-Alzheimer’s dementias

Authors: Soltis, Anthony R., Viollet, Coralie, Sukumar, Gauthaman, Alba, Camille, Lott, Nathaniel, McGrath Martinez, Elisa, Tuck, Meila, Singh, Jatinder, Bacikova, Dagmar, Zhang, Xijun, Hupalo, Daniel N., Adeleye, Adelani, Wilkerson, Matthew D., Pollard, Harvey B., Dalgard, Clifton L., Black, Sandra E., Gan-Or, Ziv, Keith, Julia, Masellis, Mario, Rogaeva, Ekaterina, Brice, Alexis, Lesage, Suzanne, Xiromerisiou, Georgia, Calvo, Andrea, Canosa, Antonio, Chio, Adriano, Logroscino, Giancarlo, Mora, Gabriele, Krüger, Reijko, May, Patrick, Alcolea, Daniel, Clarimon, Jordi, Fortea, Juan, Gonzalez-Aramburu, Isabel, Infante, Jon, Lage, Carmen, Lleó, Alberto, Pastor, Pau, Sanchez-Juan, Pascual, Brett, Francesca, Aarsland, Dag, Al-Sarraj, Safa, Attems, Johannes, Gentleman, Steve, Hardy, John A., Hodges, Angela K., Love, Seth, McKeith, Ian G., Morris, Christopher M., Morris, Huw R., Palmer, Laura, Pickering-Brown, Stuart, Ryten, Mina, Thomas, Alan J., Troakes, Claire, Albert, Marilyn S., Barrett, Matthew J., Beach, Thomas G., Bekris, Lynn M., Bennett, David A., Boeve, Bradley F., Dawson, Ted M., Dickson, Dennis W., Faber, Kelley, Ferman, Tanis, Ferrucci, Luigi, Flanagan, Margaret E., Foroud, Tatiana M., Ghetti, Bernardino, Gibbs, J. Raphael, Goate, Alison, Goldstein, David S., Graff-Radford, Neill R., Kaufmann, Horacio, Kukull, Walter A., Leverenz, James B., Lopez, Grisel, Mao, Qinwen, Masliah, Eliezer, Monuki, Edwin, Newell, Kathy L., Palma, Jose-Alberto, Perkins, Matthew, Pletnikova, Olga, Renton, Alan E., Resnick, Susan M., Rosenthal, Liana S., Ross, Owen A., Scherzer, Clemens R., Serrano, Geidy E., Shakkottai, Vikram G., Sidransky, Ellen, Tanaka, Toshiko, Tayebi, Nahid, Topol, Eric, Torkamani, Ali, Troncoso, Juan C., Woltjer, Randy, Wszolek, Zbigniew K., Scholz, Sonja W., Baloh, Robert H., Bowser, Robert, Broach, James, Camu, William, Chiò, Adriano, Cooper-Knock, John, Drepper, Carsten, Drory, Vivian E., Dunckley, Travis L., Feldman, Eva, Fratta, Pietro, Gerhard, Glenn, Gibson, Summer B., Glass, Jonathan D., Harms, Matthew B., Heiman-Patterson, Terry D., Jansson, Lilja, Kirby, Janine, Kwan, Justin, Laaksovirta, Hannu, Landers, John E., Landi, Francesco, Le Ber, Isabelle, Lumbroso, Serge, MacGowan, Daniel J.L., Maragakis, Nicholas J., Mouzat, Kevin, Myllykangas, Liisa, Orrell, Richard W., Ostrow, Lyle W., Pamphlett, Roger, Pioro, Erik, Pulst, Stefan M., Ravits, John M., Robberecht, Wim, Rothstein, Jeffrey D., Sendtner, Michael, Shaw, Pamela J., Sidle, Katie C., Simmons, Zachary, Stein, Thor, Stone, David J., Tienari, Pentti J., Traynor, Bryan J., Valori, Miko, Van Damme, Philip, Van Deerlin, Vivianna M., Van Den Bosch, Ludo, Zinman, Lorne, Kaivola, Karri, Chia, Ruth, Ding, Jinhui, Rasheed, Memoona, Fujita, Masashi, Menon, Vilas, Walton, Ronald L., Collins, Ryan L., Billingsley, Kimberley, Brand, Harrison, Talkowski, Michael, Zhao, Xuefang, Dewan, Ramita, Stark, Ali, Ray, Anindita, Solaiman, Sultana, Alvarez Jerez, Pilar, Malik, Laksh, Tienari, Pentti, Mazzini, Letizia, D'Alfonso, Sandra, Moglia, Cristina, De Jager, Philip L.

Source: In Cell Genomics 14 June 2023 3(6)

Multiomic analysis of uterine leiomyomas in self-described Black and White women: molecular insights into health disparities

Authors: Bateman, Nicholas W., Abulez, Tamara, Tarney, Christopher M., Bariani, Maria V., Driscoll, Jordan A., Soltis, Anthony R., Zhou, Ming, Hood, Brian L., Litzi, Tracy, Conrads, Kelly A., Jackson, Amanda, Oliver, Julie, Ganakammal, Satishkumar Ranganathan, Schneider, Frank, Dalgard, Clifton L., Wilkerson, Matthew D., Smith, Barbara, Borda, Victor, O’Connor, Timothy, Segars, James, Shobeiri, S. Abbas, Phippen, Neil T., Darcy, Kathleen M., Al-Hendy, Ayman, Conrads, Thomas P., Maxwell, George Larry

Source: In American Journal of Obstetrics and Gynecology September 2024 231(3):321-321

Recruitment of MLL1 complex is essential for SETBP1 to induce myeloid transformation

Authors: Nguyen, Nhu, Gudmundsson, Kristbjorn O., Soltis, Anthony R., Oakley, Kevin, Roy, Kartik R., Han, Yufen, Gurnari, Carmelo, Maciejewski, Jaroslaw P., Crouch, Gary, Ernst, Patricia, Dalgard, Clifton L., Du, Yang

Source: In iScience 21 January 2022 25(1)

Peptide ancestry informative markers in uterine neoplasms from women of European, African, and Asian ancestry

Authors: Bateman, Nicholas W., Tarney, Christopher M., Abulez, Tamara S., Hood, Brian L., Conrads, Kelly A., Zhou, Ming, Soltis, Anthony R., Teng, Pang-Ning, Jackson, Amanda, Tian, Chunqiao, Dalgard, Clifton L., Wilkerson, Matthew D., Kessler, Michael D., Goecker, Zachary, Loffredo, Jeremy, Shriver, Craig D., Hu, Hai, Cote, Michele, Parker, Glendon J., Segars, James, Al-Hendy, Ayman, Risinger, John I., Phippen, Neil T., Casablanca, Yovanni, Darcy, Kathleen M., Maxwell, G. Larry, Conrads, Thomas P., O'Connor, Timothy D.

Source: In iScience 21 January 2022 25(1)

Apolipoprotein e (APOE) ε4 genotype influences memory performance following remote traumatic brain injury in U.S. military service members and veterans

Authors: Merritt, Victoria C., Lange, Rael T., Lippa, Sara M., Brickell, Tracey A., Soltis, Anthony R., Dalgard, Clifton L., Gill, Jessica M., French, Louis M.

Source: In Brain and Cognition November 2021 154

Apolipoprotein E e4 is associated with worse self-reported neurobehavioral symptoms following uncomplicated mild traumatic brain injury in U.S. military service members

Authors: Lange, Rael T. ^*, Merritt, Victoria C., Brickell, Tracey A., Dalgard, Clifton L., Soltis, Anthony R., Hershaw, Jamie, Lippa, Sara M., Gill, Jessica, French, Louis M.

Source: In Behavioural Brain Research 11 October 2021 415

Pathogenic Huntingtin Repeat Expansions in Patients with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis

Authors: Adeleye, Adelani, Alba, Camille, Bacikova, Dagmar, Hupalo, Daniel N., Martinez, Elisa McGrath, Pollard, Harvey B., Sukumar, Gauthaman, Soltis, Anthony R., Tuck, Meila, Zhang, Xijun, Wilkerson, Matthew D., Smith, Bradley N., Ticozzi, Nicola, Fallini, Claudia, Gkazi, Athina Soragia, Topp, Simon D., Kost, Jason, Scotter, Emma L., Kenna, Kevin P., Miller, Jack W., Tiloca, Cinzia, Vance, Caroline, Danielson, Eric W., Troakes, Claire, Colombrita, Claudia, Al-Sarraj, Safa, Lewis, Elizabeth A., King, Andrew, Calini, Daniela, Pensato, Viviana, Castellotti, Barbara, de Belleroche, Jacqueline, Baas, Frank, ten Asbroek, Anneloor L.M.A., Sapp, Peter C., McKenna-Yasek, Diane, McLaughlin, Russell L., Polak, Meraida, Asress, Seneshaw, Esteban-Pérez, Jesús, Muñoz-Blanco, José Luis, Stevic, Zorica, D’Alfonso, Sandra, Mazzini, Letizia, Comi, Giacomo P., Del Bo, Roberto, Ceroni, Mauro, Gagliardi, Stella, Querin, Giorgia, Bertolin, Cinzia, van Rheenen, Wouter, Diekstra, Frank P., Rademakers, Rosa, van Blitterswijk, Marka, Boylan, Kevin B., Lauria, Giuseppe, Duga, Stefano, Corti, Stefania, Cereda, Cristina, Corrado, Lucia, Sorarù, Gianni, Williams, Kelly L., Nicholson, Garth A., Blair, Ian P., Leblond-Manry, Claire, Rouleau, Guy A., Hardiman, Orla, Morrison, Karen E., Veldink, Jan H., van den Berg, Leonard H., Al-Chalabi, Ammar, Pall, Hardev, Shaw, Pamela J., Turner, Martin R., Talbot, Kevin, Taroni, Franco, García-Redondo, Alberto, Wu, Zheyang, Gellera, Cinzia, Ratti, Antonia, Brown, Robert H., Jr., Shaw, Christopher E., Ambrose, John C., Arumugam, Prabhu, Baple, Emma L., Bleda, Marta, Boardman-Pretty, Freya, Boissiere, Jeanne M., Boustred, Christopher R., Brittain, H., Caulfield, Mark J., Chan, Georgia C., Craig, Clare E.H., Daugherty, Louise C., de Burca, Anna, Devereau, Andrew, Elgar, Greg, Foulger, Rebecca E., Fowler, Tom, Furió-Tarí, Pedro, Hackett, Joanne M., Halai, Dina, Hamblin, Angela, Henderson, Shirley, Holman, James E., Hubbard, Tim J.P., Jackson, Rob, Jones, Louise J., Kasperaviciute, Dalia, Kayikci, Melis, Lahnstein, Lea, Lawson, Kay, Leigh, Sarah E.A., Leong, Ivonne U.S., Lopez, Javier F., Maleady-Crowe, Fiona, Mason, Joanne, McDonagh, Ellen M., Moutsianas, Loukas, Mueller, Michael, Murugaesu, Nirupa, Need, Anna C., Odhams, Chris A., Patch, Christine, Perez-Gil, Daniel, Polychronopoulos, Dimitris, Pullinger, John, Rahim, Tahrima, Rendon, Augusto, Riesgo-Ferreiro, Pablo, Rogers, Tim, Savage, Kevin, Sawant, Kushmita, Scott, Richard H., Siddiq, Afshan, Sieghart, Alexander, Smedley, Damian, Smith, Katherine R., Sosinsky, Alona, Spooner, William, Stevens, Helen E., Stuckey, Alexander, Sultana, Razvan, Thomas, Ellen R.A., Thompson, Simon R., Tregidgo, Carolyn, Walsh, Emma, Watters, Sarah A., Welland, Matthew J., Williams, Eleanor, Witkowska, Katarzyna, Wood, Suzanne M., Zarowiecki, Magdalena, Arepalli, Sampath, Auluck, Pavan, Baloh, Robert H., Bowser, Robert, Brice, Alexis, Broach, James, Camu, William, Chiò, Adriano, Cooper-Knock, John, Corcia, Philippe, Drepper, Carsten, Drory, Vivian E., Dunckley, Travis L., Faghri, Faraz, Farren, Jennifer, Feldman, Eva, Floeter, Mary Kay, Fratta, Pietro, Gerhard, Glenn, Gibson, Summer B., Goutman, Stephen A., Heiman-Patterson, Terry D., Hernandez, Dena G., Hoover, Ben, Jansson, Lilja, Kamel, Freya, Kirby, Janine, Kowall, Neil W., Laaksovirta, Hannu, Landi, Francesco, Le Ber, Isabelle, Lumbroso, Serge, MacGowan, Daniel JL., Maragakis, Nicholas J., Mora, Gabriele, Mouzat, Kevin, Myllykangas, Liisa, Nalls, Mike A., Orrell, Richard W., Ostrow, Lyle W., Pamphlett, Roger, Pioro, Erik, Pulst, Stefan M., Ravits, John M., Renton, Alan E., Robberecht, Wim, Robey, Ian, Rogaeva, Ekaterina, Rothstein, Jeffrey D., Sendtner, Michael, Sidle, Katie C., Simmons, Zachary, Stone, David J., Tienari, Pentti J., Trojanowski, John Q., Troncoso, Juan C., Valori, Miko, Van Damme, Philip, Van Den Bosch, Ludo, Zinman, Lorne, Albani, Diego, Borroni, Barbara, Padovani, Alessandro, Bruni, Amalia, Clarimon, Jordi, Dols-Icardo, Oriol, Illán-Gala, Ignacio, Lleó, Alberto, Danek, Adrian, Galimberti, Daniela, Scarpini, Elio, Serpente, Maria, Graff, Caroline, Chiang, Huei-Hsin, Khoshnood, Behzad, Öijerstedt, Linn, Morris, Christopher M., Nacmias, Benedetta, Sorbi, Sandro, Nielsen, Jorgen E., Hjermind, Lynne E., Novelli, Valeria, Puca, Annibale A., Pastor, Pau, Alvarez, Ignacio, Diez-Fairen, Monica, Aguilar, Miquel, Perneczky, Robert, Diehl-Schimd, Janine, Rossi, Mina, Ruiz, Agustin, Boada, Mercè, Hernández, Isabel, Moreno-Grau, Sonia, Schlachetzki, Johannes C., Aarsland, Dag, Albert, Marilyn S., Attems, Johannes, Barrett, Matthew J., Beach, Thomas G., Bekris, Lynn M., Bennett, David A., Besser, Lilah M., Bigio, Eileen H., Black, Sandra E., Boeve, Bradley F., Bohannan, Ryan C., Brett, Francesca, Brunetti, Maura, Caraway, Chad A., Palma, Jose-Alberto, Calvo, Andrea, Canosa, Antonio, Dickson, Dennis, Duyckaerts, Charles, Faber, Kelley, Ferman, Tanis, Flanagan, Margaret E., Floris, Gianluca, Foroud, Tatiana M., Fortea, Juan, Gan-Or, Ziv, Gentleman, Steve, Ghetti, Bernardino, Gibbs, Jesse Raphael, Goate, Alison, Goldstein, David, González-Aramburu, Isabel, Graff-Radford, Neill R., Hodges, Angela K., Hu, Heng-Chen, Hupalo, Daniel, Infante, Jon, Iranzo, Alex, Kaiser, Scott M., Kaufmann, Horacio, Keith, Julia, Kim, Ronald C., Klein, Gregory, Krüger, Rejko, Kukull, Walter, Kuzma, Amanda, Lage, Carmen, Lesage, Suzanne, Leverenz, James B., Logroscino, Giancarlo, Lopez, Grisel, Love, Seth, Mao, Qinwen, Marti, Maria Jose, Martinez-McGrath, Elisa, Masellis, Mario, Masliah, Eliezer, May, Patrick, McKeith, Ian, Mesulam, Marek-Marsel, Monuki, Edwin S., Newell, Kathy L., Norcliffe-Kaufmann, Lucy, Palmer, Laura, Perkins, Matthew, Pletnikova, Olga, Molina-Porcel, Laura, Reynolds, Regina H., Rodríguez-Rodríguez, Eloy, Rohrer, Jonathan D., Sanchez-Juan, Pascual, Scherzer, Clemens R., Serrano, Geidy E., Shakkottai, Vikram, Sidransky, Ellen, Tayebi, Nahid, Thomas, Alan J., Tilley, Bension S., Walton, Ronald L., Woltjer, Randy, Wszolek, Zbigniew K., Xiromerisiou, Georgia, Zecca, Chiara, Phatnani, Hemali, Kwan, Justin, Sareen, Dhruv, Broach, James R., Arcila-Londono, Ximena, Lee, Edward B., Shneider, Neil A., Fraenkel, Ernest, Zaitlen, Noah, Berry, James D., Malaspina, Andrea, Cox, Gregory A., Thompson, Leslie M., Finkbeiner, Steve, Dardiotis, Efthimios, Miller, Timothy M., Chandran, Siddharthan, Pal, Suvankar, Hornstein, Eran, MacGowan, Daniel J., Heiman-Patterson, Terry, Hammell, Molly G., Patsopoulos, Nikolaos.A., Butovsky, Oleg, Dubnau, Joshua, Nath, Avindra, Harms, Matt, Aronica, Eleonora, Poss, Mary, Phillips-Cremins, Jennifer, Crary, John, Atassi, Nazem, Lange, Dale J., Adams, Darius J., Stefanis, Leonidas, Gotkine, Marc, Babu, Suma, Raj, Towfique, Paganoni, Sabrina, Shalem, Ophir, Smith, Colin, Zhang, Bin, Harris, Brent, Broce, Iris, Drory, Vivian, Ravits, John, McMillan, Corey, Menon, Vilas, Wu, Lani, Altschuler, Steven, Amar, Khaled, Archibald, Neil, Bandmann, Oliver, Capps, Erica, Church, Alistair, Coebergh, Jan, Costantini, Alyssa, Critchley, Peter, Ghosh, Boyd CP., Hu, Michele T.M., Kobylecki, Christopher, Leigh, P. Nigel, Mann, Carl, Massey, Luke A., Morris, Huw R., Nath, Uma, Pavese, Nicola, Paviour, Dominic, Sharma, Jagdish, Vaughan, Jenny, Dewan, Ramita, Chia, Ruth, Ding, Jinhui, Hickman, Richard A., Stein, Thor D., Abramzon, Yevgeniya, Ahmed, Sarah, Sabir, Marya S., Portley, Makayla K., Tucci, Arianna, Ibáñez, Kristina, Shankaracharya, F.N.U., Keagle, Pamela, Rossi, Giacomina, Caroppo, Paola, Tagliavini, Fabrizio, Waldo, Maria L., Johansson, Per M., Nilsson, Christer F., Rowe, James B., Benussi, Luisa, Binetti, Giuliano, Ghidoni, Roberta, Jabbari, Edwin, Viollet, Coralie, Glass, Jonathan D., Singleton, Andrew B., Silani, Vincenzo, Ross, Owen A., Ryten, Mina, Torkamani, Ali, Tanaka, Toshiko, Ferrucci, Luigi, Resnick, Susan M., Pickering-Brown, Stuart, Brady, Christopher B., Kowal, Neil, Hardy, John A., Van Deerlin, Vivianna, Vonsattel, Jean Paul, Harms, Matthew B., Ferrari, Raffaele, Landers, John E., Gibbs, J. Raphael, Dalgard, Clifton L., Scholz, Sonja W., Traynor, Bryan J.

Source: In Neuron 3 February 2021 109(3):448-460

Early epigenomic and transcriptional changes reveal Elk-1 transcription factor as a therapeutic target in Huntington’s disease

Authors: Yildirim, Ferah, Ng, Christopher W., Kappes, Vincent, Ehrenberger, Tobias, Rigby, Siobhan K., Stivanello, Victoria, Gipson, Theresa A., Soltis, Anthony R., Vanhoutte, Peter, Caboche, Jocelyne, Housman, David E., Fraenkel, Ernest

Source: Proceedings of the National Academy of Sciences of the United States of America, 2019 Dec 01. 116(49), 24840-24851.

Access URL: https://www.jstor.org/stable/26861684

Molecular Analysis of Clinically Defined Subsets of High-Grade Serous Ovarian Cancer

Authors: Lee, Sanghoon, Zhao, Li, Rojas, Christine, Bateman, Nicholas W., Yao, Hui, Lara, Olivia D., Celestino, Joseph, Morgan, Margaret B., Nguyen, Tri V., Conrads, Kelly A., Rangel, Kelly M., Dood, Robert L., Hajek, Richard A., Fawcett, Gloria L., Chu, Randy A., Wilson, Katlin, Loffredo, Jeremy L., Viollet, Coralie, Jazaeri, Amir A., Dalgard, Clifton L., Mao, Xizeng, Song, Xingzhi, Zhou, Ming, Hood, Brian L., Banskota, Nirad, Wilkerson, Matthew D., Te, Jerez, Soltis, Anthony R., Roman, Kristin, Dunn, Andrew, Cordover, David, Eterovic, Agda Karina, Liu, Jinsong, Burks, Jared K., Baggerly, Keith A., Fleming, Nicole D., Lu, Karen H., Westin, Shannon N., Coleman, Robert L., Mills, Gordon B., Casablanca, Yovanni, Zhang, Jianhua, Conrads, Thomas P., Maxwell, George L., Futreal, P. Andrew, Sood, Anil K.

Source: In Cell Reports 14 April 2020 31(2)

Hepatic Dysfunction Caused by Consumption of a High-Fat Diet

Authors: Soltis, Anthony R., Kennedy, Norman J., Xin, Xiaofeng, Zhou, Feng, Ficarro, Scott B., Yap, Yoon Sing, Matthews, Bryan J., Lauffenburger, Douglas A., White, Forest M., Marto, Jarrod A., Davis, Roger J., Fraenkel, Ernest

Source: In Cell Reports 12 December 2017 21(11):3317-3328

Proteogenomic analysis of enriched HGSOC tumor epithelium identifies prognostic signatures and therapeutic vulnerabilities.

Authors: Bateman, Nicholas W., Abulez, Tamara, Soltis, Anthony R., McPherson, Andrew, Choi, Seongmin, Garsed, Dale W., Pandey, Ahwan, Tian, Chunqiao, Hood, Brian L., Conrads, Kelly A., Teng, Pang-ning, Oliver, Julie, Gist, Glenn, Mitchell, Dave, Litzi, Tracy J., Tarney, Christopher M., Crothers, Barbara A., Mhawech-Fauceglia, Paulette, Dalgard, Clifton L., Wilkerson, Matthew D.

Source: NPJ Precision Oncology; 3/13/2024, Vol. 8 Issue 1, p1-17, 17p

Subject Terms: EPITHELIAL tumors, HOMOLOGOUS recombination, TUMOR-infiltrating immune cells, OXIDATIVE phosphorylation, PROGRESSION-free survival

MutEnricher: a flexible toolset for somatic mutation enrichment analysis of tumor whole genomes.

Authors: Soltis, Anthony R.^1,2 (AUTHOR) anthony.soltis.ctr@usuhs.edu, Dalgard, Clifton L.^1,3 (AUTHOR), Pollard, Harvey B.^1,3 (AUTHOR), Wilkerson, Matthew D.^1,2,3 (AUTHOR) matthew.wilkerson.ctr@usuhs.edu

Source: BMC Bioinformatics. 7/31/2020, Vol. 21 Issue 1, p1-8. 8p. 2 Diagrams.

Subject Terms: *SOMATIC mutation, *CANCER genes, *FLEXIBLE packaging, *NUCLEOTIDE sequencing, *INTEGRATED software, *EXOMES

Synergy between CaMKII Substrates and β-Adrenergic Signaling in Regulation of Cardiac Myocyte Ca 2+ Handling

Authors: Soltis, Anthony R., Saucerman, Jeffrey J.

Source: In Biophysical Journal 2010 99(7):2038-2047

Transcriptomic Profiling and Pathway Analysis of Mesenchymal Stem Cells Following Low Dose-Rate Radiation Exposure.

Authors: Slaven, John E., Wilkerson, Matthew, Soltis, Anthony R., Rittase, W. Bradley, Bradfield, Dmitry T., Bylicky, Michelle, Cary, Lynnette, Tsioplaya, Alena, Bouten, Roxane, Dalgard, Clifton, Day, Regina M.

Source: Antioxidants; Feb2023, Vol. 12 Issue 2, p241, 28p

Subject Terms: RADIATION exposure, MESENCHYMAL stem cells, DOSE-response relationship (Radiation), DNA repair, HUMAN stem cells, RADIATION injuries, IONIZING radiation

APOE Is Associated With Serum Tau Following Uncomplicated Mild Traumatic Brain Injury.

Authors: Lippa, Sara M., Lange, Rael T., Dalgard, Clifton L., Soltis, Anthony R., Guedes, Vivian A., Brickell, Tracey A., French, Louis M., Gill, Jessica

Source: Frontiers in Neurology; 7/14/2022, Vol. 13, p1-7, 7p

Subject Terms: BRAIN injuries, APOLIPOPROTEIN E

Rare variant association study of veteran twin whole-genomes links severe depression with a nonsynonymous change in the neuronal gene BHLHE22.

Authors: Hupalo, Daniel, Forsberg, Christopher W., Goldberg, Jack, Kremen, William S., Lyons, Michael J., Soltis, Anthony R., Viollet, Coralie, Ursano, Robert J., Stein, Murray B., Franz, Carol E., Sun, Yan V., Vaccarino, Viola, Smith, Nicholas L., Dalgard, Clifton L., Wilkerson, Matthew D., Pollard, Harvey B.

Source: World Journal of Biological Psychiatry; Mar/Apr2022, Vol. 23 Issue 4, p295-306, 12p

Subject Terms: EXOMES, FISHER exact test, GENETIC variation, MENTAL depression, HUMAN genome, NUCLEOTIDE sequencing, HERITABILITY

Transcriptomic profiling and pathway analysis of cultured human lung microvascular endothelial cells following ionizing radiation exposure.

Authors: Bouten, Roxane M., Dalgard, Clifton L., Soltis, Anthony R., Slaven, John E., Day, Regina M.

Source: Scientific Reports; 12/20/2021, Vol. 11 Issue 1, p1-18, 18p

Subject Terms: IONIZING radiation, ENDOTHELIAL cells, RADIATION exposure, GENE expression, CARDIOVASCULAR system, LUNGS

Survival motor neuron deficiency slows myoblast fusion through reduced myomaker and myomixer expression.

Authors: McCormack, Nikki M., Villalón, Eric, Viollet, Coralie, Soltis, Anthony R., Dalgard, Clifton L., Lorson, Christian L., Burnett, Barrington G.

Source: Journal of Cachexia, Sarcopenia & Muscle; Aug2021, Vol. 12 Issue 4, p1098-1116, 19p

Subject Terms: MOTOR neurons, MYOBLASTS, SPINAL muscular atrophy, MUSCLE proteins, CHIMERIC proteins, CELL fusion, SKELETAL muscle

Tensin 1 (TNS1) is a modifier gene for low body mass index (BMI) in homozygous [F508del]CFTR patients.

Authors: Walton, Nathan I., Zhang, Xijun, Soltis, Anthony R., Starr, Joshua, Dalgard, Clifton L., Wilkerson, Matthew D., Conrad, Douglas, Pollard, Harvey B.

Source: Physiological Reports; Jun2021, Vol. 9 Issue 11, p1-12, 12p

Subject Terms: BODY mass index, RECESSIVE genes, NUCLEOTIDE sequencing, CYSTIC fibrosis, PHENOTYPIC plasticity, GENES, GENITOURINARY diseases

Geographic Terms: SAN Diego (Calif.)

Company/Entity: UNIVERSITY of California (System)