Moving beyond multi-triazole to multi-fungicide resistance: Broader selection of drug resistance in the human fungal pathogen Aspergillus fumigatus.

Authors: Kanellopoulos, Spyros G.¹ (AUTHOR), Snelders, Eveline¹ (AUTHOR) eveline.snelders@wur.nl

Source: PLoS Pathogens. 2/10/2025, Vol. 21 Issue 2, p1-6. 6p.

Subject Terms: *FUNGICIDE resistance, *TANDEM repeats, *ASPERGILLOSIS, *WHOLE genome sequencing, *AGRICULTURE, *DIHYDROOROTATE dehydrogenase, *ANTIFUNGAL agents

The role of glycosylphosphatidylinositol (gpi) anchored proteins in Cryptococcusneoformans

Authors: Snelders, Eveline, Moyrand, Frédérique, Sturny-Leclère, Aude, Vernel-Pauillac, Frédérique, Volant, Stevenn, Janbon, Guilhem, Alanio, Alexandre

Source: In Microbes and Infection November-December 2022 24(8)

Relevance of heterokaryosis for adaptation and azole-resistance development in Aspergillus fumigatus

Authors: Zhang, Jianhua, Snelders, Eveline E., Zwaan, Bas J., Schoustra, Sijmen E., Kuijper, Ed J., Arendrup, Maiken C., Melchers, Willem J. G., Verweij, Paul E., Debets, Alfons J. M.

Source: Proceedings: Biological Sciences, 2019 Feb 01. 286(1896), 1-10.

Access URL: https://www.jstor.org/stable/26616289

The human fungal pathogen Aspergillus fumigatus can produce the highest known number of meiotic crossovers.

Authors: Auxier, Ben¹, Debets, Alfons J. M.¹, Stanford, Felicia Adelina², Rhodes, Johanna³, Becker, Frank M.¹, Reyes Marquez, Francisca¹, Nijland, Reindert⁴, Dyer, Paul S.², Fisher, Matthew C.³, van den Heuvel, Joost¹, Snelders, Eveline¹, eveline.snelders@wur.nl

Source: PLoS Biology; 9/14/2023, Vol. 21 Issue 9, p1-17, 17p, 1 Diagram, 3 Graphs

Clinical Implications of Azole Resistance in Aspergillus fumigatus, the Netherlands, 2007-2009.

Authors: Van Der Linden, Jan W. M., Snelders, Eveline, Kampinga, Greetje A.

Source: Emerging Infectious Diseases; October 2011, Vol. 17 Issue 10, p1846-1854, 9p

The Narrow Footprint of Ancient Balancing Selection Revealed by Heterokaryon Incompatibility Genes in Aspergillus fumigatus.

Authors: Auxier, Ben, Zhang, Jianhua, Marquez, Francisca Reyes, Senden, Kira, van den Heuvel, Joost, Aanen, Duur K, Snelders, Eveline, Debets, Alfons J M

Source: Molecular Biology & Evolution; May2024, Vol. 41 Issue 5, p1-14, 14p

Subject Terms: ASPERGILLUS fumigatus, GENE expression, GENES, LINKAGE disequilibrium, BASE pairs

Genotype–phenotype complexity of the TR46/Y121F/T289A cyp51A azole resistance mechanism in Aspergillus fumigatus

Authors: Snelders, Eveline, Camps, Simone M.T., Karawajczyk, Anna, Rijs, Antonius J.M.M., Zoll, Jan, Verweij, Paul E., Melchers, Willem J.G.

Source: In Fungal Genetics and Biology September 2015 82:129-135

Extended-Spectrum β-Lactamase–Producing Enterobacteriaceae in Hospital Food: A Risk Assessment

Authors: Stewardson, Andrew J., Renzi, Gesuele, Maury, Nathalie, Vaudaux, Celia, Brossier, Caroline, Fritsch, Emmanuel, Pittet, Didier, Heck, Max, van der Zwaluw, Kim, Reuland, E. Ascelijn, van de Laar, Thijs, Snelders, Eveline, Vandenbroucke-Grauls, Christina, Kluytmans, Jan, Edder, Patrick, Schrenzel, Jacques, Harbarth, Stephan

Source: Infection Control and Hospital Epidemiology, 2014 Apr 01. 35(4), 375-383.

Access URL: https://www.jstor.org/stable/10.1086/675609

Discrimination of Aspergillosis, Mucormycosis, Fusariosis, and Scedosporiosis in Formalin-Fixed Paraffin-Embedded Tissue Specimens by Use of Multiple Real-Time Quantitative PCR Assays

Authors: Salehi, Elham, Hedayati, Mohammad T., Zoll, Jan, Rafati, Haleh, Ghasemi, Maryam, Doroudinia, Atosa, Abastabar, Mahdi, Tolooe, Ali, Snelders, Eveline, van der Lee, Henrich A.

Source: Journal of clinical microbiology. 54(11):2798-2803

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN608448522&indx=1&recIds=ETOCRN608448522

Preterm prelabor rupture of membranes (PPROM) is not associated with presence of viral genomes in the amniotic fluid

Authors: Bopegamage, Shubhada, Kacerovsky, Marian, Tambor, Vojtech, Musilova, Ivana, Sarmirova, Sona, Snelders, Eveline, de Jong, Arjan S., Vari, Sandor G., Melchers, Willem J.G., Galama, Jochem M.D.

Source: In Journal of Clinical Virology November 2013 58(3):559-563

Respiratory infections in Eñepa Amerindians are related to malnutrition and Streptococcus pneumoniae carriage

Authors: Verhagen, Lilly M., Gómez-Castellano, Keyla, Snelders, Eveline, Rivera-Olivero, Ismar, Pocaterra, Leonor, Melchers, Willem J.G., de Waard, Jacobus H., Hermans, Peter W.M.

Source: In Journal of Infection October 2013 67(4):273-281

Occurrence of virus-induced COPD exacerbations during four seasons

Authors: Djamin, Remco S., Uzun, Sevim, Snelders, Eveline, Kluytmans, Jan J. W., Hoogsteden, Henk C., Aerts, Joachim G. J. V., Van Der Eerden, Menno M.

Source: Infectious diseases. 47(2):96-100

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100105359457.0x000001&indx=1&recIds=ETOCvdc_100105359457.0x000001

Environmental Hotspots for Azole Resistance Selection of Aspergillus fumigatus, the Netherlands.

Authors: Schoustra, Sijmen E.¹, sijmen.schoustra@wur.nl, Debets, Alfons J. M.¹, Rijs, Antonius J. M. M.², Jianhua Zhang¹, Snelders, Eveline¹, Leendertse, Peter C.³, Melchers, Willem J. G.^2,3, Rietveld, Anton G.⁴, Zwaan, Bas J.¹, Verweij, Paul E.^2,5, Zhang, Jianhua

Source: Emerging Infectious Diseases; Jul2019, Vol. 25 Issue 7, p1347-1353, 7p

The structure–function relationship of the Aspergillus fumigatuscyp51A L98H conversion by site-directed mutagenesis: The mechanism of L98H azole resistance

Authors: Snelders, Eveline, Karawajczyk, Anna, Verhoeven, Rob J.A., Venselaar, Hanka, Schaftenaar, Gijs, Verweij, Paul E., Melchers, Willem J.G.

Source: In Fungal Genetics and Biology November 2011 48(11):1062-1070

High-Level Pan-Azole-Resistant Aspergillosis

Authors: van Ingen, Jakko, van der Lee, Henrich A. L., Rijs, Antonius J. M. M., Snelders, Eveline, Melchers, Wiliem J. G., Verweij, Paul E.

Source: Journal of clinical microbiology. 53(7):2343-2345

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN601803810&indx=1&recIds=ETOCRN601803810

Generation of Affibody ligands binding interleukin-2 receptor α/CD25.

Authors: Grönwall, Caroline, Snelders, Eveline, Palm, Anna Jarelöv

Source: Biotechnology & Applied Biochemistry; June 2008, Vol. 50 Issue 2, p97-112, 16p

Trends in Azole Resistance in Aspergillus fumigatus, the Netherlands, 1994-2016.

Authors: Buil, Jochem B.^1,2 jochem.buil@radboudumc.nl, Snelders, Eveline³, Denardi, Laura Bedin⁴, Melchers, Willem J. G.^1,2, Verweij, Paul E.^1,2

Source: Emerging Infectious Diseases. Jan2019, Vol. 25 Issue 1, p176-178. 3p. 1 Graph.

Subject Terms: *ASPERGILLUS fumigatus, *AZOLES, *DISEASE prevalence, *ASPERGILLUS, *EPIDEMIOLOGY

Flower Bulb Waste Material Is a Natural Niche for the Sexual Cycle in Aspergillus fumigatus.

Authors: Zhang, Jianhua, Verweij, Paul E., Rijs, Antonius J. M. M., Debets, Alfons J. M., Snelders, Eveline

Source: Frontiers in Cellular & Infection Microbiology; 1/21/2022, p1-10, 10p

Subject Terms: BULBS (Plants), WASTE products, SEXUAL cycle, ASPERGILLUS fumigatus, GENETIC recombination, COMPOSTING

Azole-Resistance Development; How the Aspergillus fumigatus Lifecycle Defines the Potential for Adaptation.

Authors: Jianhua Zhang, Debets, Alfons J. M., Verweij, Paul E., Snelders, Eveline

Source: Journal of Fungi; Aug2021, Vol. 7 Issue 8, p1-12, 12p

Subject Terms: ASPERGILLUS fumigatus, AZOLES, PHENOTYPIC plasticity, GENETIC variation, ANTIFUNGAL agents

Triazole Fungicides Can Induce Cross-Resistance to Medical Triazoles in Aspergillus fumigatus.

Authors: Snelders, Eveline^1,2, Camps, Simone M. T.^1,2, Karawajczyk, Anna^3,4, Schaftenaar, Gijs³, Kema, Gert H. J.⁵, Van der Lee, Henrich A.^1,2, Klaassen, Corné H.⁶, Melchers, Willem J. G.^1,2, Verweij, Paul E.^1,2 p.verweij@mmb.umcn.nl

Source: PLoS ONE. Mar2012, Vol. 7 Issue 3, p1-11. 11p.

Subject Terms: *TRIAZOLES, *FUNGICIDES, *ASPERGILLOSIS treatment, *ASPERGILLUS fumigatus, *HERBICIDES, *PLANT regulators