The Minimum Significant Ratio: A Statistical Parameter to Characterize the Reproducibility of Potency Estimates from Concentration-Response Assays and Estimation by Replicate-Experiment Studies

Authors: Eastwood, Brian J. ^*, Farmen, Mark W., Iversen, Philip W., Craft, Trelia J., Smallwood, Jeffrey K., Garbison, Kim E., Delapp, Neil W., Smith, Gerald F.

Source: In SLAS Discovery April 2006 11(3):253-261

Complete Inhibition of Anisomycin and UV Radiation but Not Cytokine Induced JNK and p38 Activation by an Aryl-substituted Dihydropyrrolopyrazole Quinoline and Mixed Lineage Kinase 7 Small Interfering RNA

Authors: Wang, Xushan ^‡, Mader, Mary M. ^§, Toth, John E. ^§, Yu, Xiaohong ^‡, Jin, Najia ^‡, Campbell, Robert M. ^¶, Smallwood, Jeffrey K. ^¶, Christe, Michael E. ^‡, Chatterjee, Arindam ^§, Goodson, Theodore, Jr. ^§, Vlahos, Chris J. ^§, Matter, William F. ^‡, Bloem, Laura J. ^{‡, ∥}

Source: In Journal of Biological Chemistry 13 May 2005 280(19):19298-19305

Measurement of cardiac output in adult and newborn animals by ascorbic acid dilution.

Authors: Smallwood, Jeffrey K., Haselby, Kenneth A., Paradise, Raymond R.

Source: American Journal of Physiology; May 1984 pt2, Vol. 246, pH733-H738, 6p

Investigation of the terminal P4 domain in a series of d-phenylglycinamide-based factor Xa inhibitors

Authors: Franciskovich, Jeffry B., Masters, John J., Weber, Wayne W., Klimkowski, Valentine J., Chouinard, Michael, Sipes, Philip R., Johnson, Lea M., Snyder, David W., Chastain, Marcia K., Craft, Trelia J., Towner, Richard D., Gifford-Moore, Donetta S., Froelich, Larry L., Smallwood, Jeffrey K., Foster, Ronald S., Smith, Gerald F., Liebeschuetz, John W., Murray, Christopher W., Young, Stephen C.

Source: In Bioorganic & Medicinal Chemistry Letters 2007 17(24):6910-6913

d-Phenylglycinol-derived non-covalent factor Xa inhibitors: Effect of non-peptidic S4 linkage elements on affinity and anticoagulant activity

Authors: Klimkowski, Valentine J., Watson, Brian M., Wiley, Michael R., Liebeschuetz, John, Franciskovich, Jeffry B., Marimuthu, Jothirajah, Bastian, Jolie A., Sall, Daniel J., Smallwood, Jeffrey K., Chirgadze, Nikolay Y., Smith, Gerald F., Foster, Ronald S., Craft, Trelia, Sipes, Philip, Chastain, Marcia, Sheehan, Scott M.

Source: In Bioorganic & Medicinal Chemistry Letters 2007 17(21):5801-5805

Investigation of factor Xa inhibitors containing non-amidine S1 elements

Authors: Franciskovich, Jeffry B., Masters, John J., Tinsley, Jennifer M., Craft, Trelia J., Froelich, Larry L., Gifford-Moore, Donetta S., Klimkowski, Valentine J., Smallwood, Jeffrey K., Smith, Gerald F., Smith, Tommy, Towner, Richard R., Weir, Leonard C., Wiley, Michael R.

Source: In Bioorganic & Medicinal Chemistry Letters 2005 15(21):4838-4841

A four component coupling strategy for the synthesis of d-phenylglycinamide-derived non-covalent factor Xa inhibitors

Authors: Sheehan, Scott M., Masters, John J., Wiley, Michael R., Young, Stephen C., Liebeschuetz, John W., Jones, Stuart D., Murray, Christopher W., Franciskovich, Jeffrey B., Engel, David B., Weber, Wayne W., II, Marimuthu, Jothirajah, Kyle, Jeffrey A., Smallwood, Jeffrey K., Farmen, Mark W., Smith, Gerald F.

Source: In Bioorganic & Medicinal Chemistry Letters 2003 13(14):2255-2259

Inhibition of Granulocyte cAMP-Phosphodiesterase by Rolipram In Vivo Is Not Sufficient to Protect the Canine Myocardium from Reperfusion Injury.

Authors: Simpson, Paul J., Schelm, Judith A., Smallwood, Jeffrey K., Clay, Michael P., Lindstrom, Terry D.

Source: Journal of Cardiovascular Pharmacology; Jun1992, Vol. 19 Issue 6, p987-995, 9p

LY249933.

Authors: Holland, Donald R., Wikel, James H., Kauffman, Raymond F., Smallwood, Jeffrey K., Zimmerman, Karen M., Utterback, Barbara G., Turk, John A., Steinberg, Mitchell I.

Source: Journal of Cardiovascular Pharmacology; Sep1989, Vol. 14 Issue 3, p483-491, 9p

The Relation Between Vascular Relaxant and Cardiac Electrophysiological Effects of Pinacidil.

Authors: Steinberg, Mitchell I., Ertel, Phil, Smallwood, Jeffrey K., Wyss, Virginia, Zimmerman, Karen

Source: Journal of Cardiovascular Pharmacology; 1988 Supplement2, Vol. 12, pS30-S40, 11p

Cardiac Electrophysiological Effects of Pinacidil and Related Pyridylcyanoguanidines.

Authors: Smallwood, Jeffrey K., Steinberg, Mitchell I.

Source: Journal of Cardiovascular Pharmacology; Jul1988, Vol. 12 Issue 1, p102-109, 8p

Effect of Activation of ATP-Dependent Potassium Channels with (-)-Pinacidil and (-)-3-Pyridyl Pinacidil on Infarct Size in a Canine Model of Ischemia-Reperfusion Injury.

Authors: Smallwood, Jeffrey K., Schelm, Judith A., Bemis, Kerry G., Simpson, Paul J.

Source: Journal of Cardiovascular Pharmacology; Nov1993, Vol. 22 Issue 5, p731-743, 13p

Inhibition of Granulocyte cAMPPhosphodiesterase by Rolipram In Vivo Is Not Sufficient to Protect the Canine Myocardium from Reperfusion Injury

Authors: Simpson, Paul J., Schelm, Judith A., Smallwood, Jeffrey K., Clay, Michael P., Lindstrom, Terry D.

Source: Journal of Cardiovascular Pharmacology; June 1992, Vol. 19 Issue: 6 p987-995, 9p

Effect of Activation of ATPDependent Potassium Channels with Pinacidil and 3Pyridyl Pinacidil on Infarct Size in a Canine Model of IschemiaReperfusion Injury

Authors: Smallwood, Jeffrey K., Schelm, Judith A., Bemis, Kerry G., Simpson, Paul J.

Source: Journal of Cardiovascular Pharmacology; November 1993, Vol. 22 Issue: 5 p731-743, 13p

Electrophysiological effects of flecainide enantiomers in canine Purkinje fibres

Authors: Smallwood, Jeffrey K., Robertson, David W., Steinberg, Mitchell I.

Source: Naunyn-Schmiedeberg's Archives of Pharmacology; June 1989, Vol. 339 Issue: 6 p625-629, 5p

Modification by glibenclamide of the electrophysiological consequences of myocardial ischaemia in dogs and rabbits

Authors: Smallwood, Jeffrey K., Ertel, Phillip J., Steinberg, Mitchell I.

Source: Naunyn-Schmiedeberg's Archives of Pharmacology; August 1990, Vol. 342 Issue: 2 p214-220, 7p

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Phenothiazine and phenoxazine derivatives of nafazatrom. In vitro evaluation as 5-lipoxygenase and iron-dependent lipid peroxidation inhibitors.

Authors: Yu, Melvin J., McCowan, Jefferson R., Bertsch, Barbara, Ho, Peter P.K., Phebus, Lee A., Ruterbories, Kenneth J., Lindstrom, Terry D., Smallwood, Jeffrey K., Simpson, Paul J.

Source: In Bioorganic & Medicinal Chemistry Letters 1992 2(1):59-62

Hemodynamic and electrocardiographic effects of fluoxetine and its major metabolite, norfluoxetine, in anesthetized dogs

Authors: Steinberg, Mitchell I., Smallwood, Jeffrey K., Holland, Donald R., Bymaster, Frank P., Bemis, Kerry G.

Source: In Toxicology and Applied Pharmacology 1986 82(1):70-79