Spatial mapping of protein composition and tissue organization: a primer for multiplexed antibody-based imaging

Authors: Hickey, John W., Neumann, Elizabeth K., Radtke, Andrea J., Camarillo, Jeannie M., Beuschel, Rebecca T., Albanese, Alexandre, McDonough, Elizabeth, Hatler, Julia, Wiblin, Anne E., Fisher, Jeremy, Croteau, Josh, Small, Eliza C., Sood, Anup, Caprioli, Richard M., Angelo, R. Michael, Nolan, Garry P., Chung, Kwanghun, Hewitt, Stephen M., Germain, Ronald N., Spraggins, Jeffrey M., Lundberg, Emma, Snyder, Michael P., Kelleher, Neil L., Saka, Sinem K.

Subject Terms: Quantitative Biology - Tissues and Organs

Access URL: http://arxiv.org/abs/2107.07953

Chromatin Immunoprecipitation (ChIP) to Study DNA—Protein Interactions

Authors: Small, Eliza C., Maryanski, Danielle N., Rodriguez, Keli L., Harvey, Kevin J., Keogh, Michael-C., Johnstone, Andrea L.

Source: Methods in molecular biology. 2261:323-344

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN625356842&indx=1&recIds=ETOCRN625356842

UTX/KDM6A Loss Enhances the Malignant Phenotype of Multiple Myeloma and Sensitizes Cells to EZH2 inhibition

Authors: Ezponda, Teresa, Dupéré-Richer, Daphné, Will, Christine M., Small, Eliza C., Varghese, Nobish, Patel, Tej, Nabet, Behnam, Popovic, Relja, Oyer, Jon, Bulic, Marinka, Zheng, Yupeng, Huang, Xiaoxiao, Shah, Mrinal Y., Maji, Sayantan, Riva, Alberto, Occhionorelli, Manuela, Tonon, Giovanni, Kelleher, Neil, Keats, Jonathan, Licht, Jonathan D.

Source: In Cell Reports 17 October 2017 21(3):628-640

Single-cell nucleosome mapping reveals the molecular basis of gene expression heterogeneity

Authors: Small, Eliza C., Xi, Liqun, Wang, Ji-Ping, Widom, Jonathan, Licht, Jonathan D.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2014 Jun . 111(24), 8710-8710.

Access URL: http://dx.doi.org/10.1073/pnas.ss11124

The EF-G-like GTPase Snu114p Regulates Spliceosome Dynamics Mediated by Brr2p, a DExD/H Box ATPase

Authors: Small, Eliza C., Leggett, Stephanie R., Winans, Adrienne A., Staley, Jonathan P.

Source: In Molecular Cell 2006 23(3):389-399

Evaluation of Fluorescent Compound Interference in 4 Fluorescence Polarization Assays: 2 Kinases, 1 Protease, and 1 Phosphatase

Authors: Turek-Etienne, Tammy C. ^*, Small, Eliza C., Soh, Sharon C., Xin, Tianpei A., Gaitonde, Priti V., Barrabee, Ellen B., Hart, Richard F., Bryant, Robert W.

Source: In SLAS Discovery April 2003 8(2):176-184

Mechanism of Janus kinase 3-catalyzed phosphorylation of a Janus kinase 1 activation loop peptide

Authors: Wang, Ruixiu, Griffin, Patrick R, Small, Eliza C, Thompson, James E

Source: In Archives of Biochemistry and Biophysics 2003 410(1):7-15

Development and Validation of a Competitive AKT Serine/Threonine Kinase Fluorescence Polarization Assay Using a Product-Specific Anti-phospho-serine Antibody

Authors: Turek, Tammy C., Small, Eliza C., Bryant, Robert W., Adam, W., Hill, G.

Source: In Analytical Biochemistry 2001 299(1):45-53

A role for ubiquitin in the spliceosome assembly pathway.

Authors: Bellare, Priya¹, Small, Eliza C.², Huang, Xinhua³, Wohlschlegel, James A.³, Staley, Jonathan P.⁴, Sontheimer, Erik J.¹ erik@northwestern.edu

Source: Nature Structural & Molecular Biology. May2008, Vol. 15 Issue 5, p444-451. 8p. 4 Black and White Photographs, 1 Diagram, 2 Graphs.

Subject Terms: *UBIQUITIN, *MESSENGER RNA, *RNA splicing, *NUCLEOPROTEINS, *PROTEIN-protein interactions, *NUCLEIC acids

Histone Methyltransferase MMSET/NSD2 Alters EZH2 Binding and Reprograms the Myeloma Epigenome through Global and Focal Changes in H3K36 and H3K27 Methylation.

Authors: Popovic, Relja¹, Martinez-Garcia, Eva¹, Giannopoulou, Eugenia G.^2,3, Zhang, Quanwei⁴, Zhang, Qingyang⁴, Ezponda, Teresa¹, Shah, Mrinal Y.¹, Zheng, Yupeng⁵, Will, Christine M.¹, Small, Eliza C.¹, Hua, Youjia¹, Bulic, Marinka¹, Jiang, Yanwen⁶, Carrara, Matteo⁷, Calogero, Raffaele A.⁷, Kath, William L.⁸, Kelleher, Neil L.⁵, Wang, Ji-Ping⁴, Elemento, Olivier⁶, Licht, Jonathan D.¹, j-licht@northwestern.edu

Source: PLoS Genetics; Sep2014, Vol. 10 Issue 9, p1-19, 19p

Loss of the Histone Demethylase UTX Contributes to Multiple Myeloma and Sensitizes Cells to EZH2 Inhibitors

Authors: Ezponda, Teresa ^*, Popovic, Relja ^*, Zheng, Yupeng ^*, Nabet, Behnam ^*, Will, Christine ^*, Small, Eliza C ^*, Occhionorelli, Manuela ^*, Tonon, Giovanni ^*, Keats, Jonathan J., Kelleher, Neil L ^*, Licht, Jonathan D.

Source: In Blood 6 December 2014 124(21):611-611

MMSET/WHSC1 Enhances DNA Damage Repair Leading To An Increase In Resistance To Chemotherapeutic Agents

Authors: Shah, Mrinal Y. ^*, Martinez, Eva ^*, Popovic, Relja ^*, Ezponda, Teresa ^*, Small, Eliza C. ^*, Will, Christine ^*, Neri, Paola, Bahlis, Nizar J., Licht, Jonathan D.

Source: In Blood 15 November 2013 122(21):808-808

MMSET Dysregulates Gene Expression in Myeloma Through Global and Focal Changes in H3K36 and H3K27 Methylation

Authors: Popovic, Relja ^*, Martinez, Eva ^*, Zhang, Quanwei ^*, Ezponda, Teresa ^*, Jiang, Yanwen, Shah, Mrinal Y. ^*, Will, Christine ^*, Small, Eliza C. ^*, Elemento, Olivier ^*, Wang, Ji-Ping ^*, Licht, Jonathan D.

Source: In Blood 16 November 2012 120(21):523-523

Genome-wide nucleosome mapping in multiple myeloma.

Authors: Small, Eliza C.¹, Quanwei Zhang², Popovic, Relja¹, Youjia Hua¹, Wang, Ji-Ping², Licht, Jonathan D.¹

Source: Epigenetics & Chromatin. 2013, Vol. 6 Issue Suppl 1, p1-1. 1p.

Subject Terms: *CHROMATIN, *GENE expression, *MYELOMA proteins, *GENETIC regulation, *HISTONE methyltransferases

MMSET dysregulates gene expression in myeloma through global and focal changes in H3K36 and H3K27 methylation.

Authors: Popovic, Relja, Martinez-Garcia, Eva, Quanwei Zhang, Ezponda, Teresa, Shah, Mrinal Y., Yupeng Zhang, Yanwen Jiang, Will, Christine M., Small, Eliza C., Bulic, Marinka, Elemento, Olivier, Kelleher, Neil, Kath, William, Wang, Ji-Ping, Licht, Jonathan D.

Source: Epigenetics & Chromatin; 2013, Vol. 6 Issue S1, p1-2, 2p

Subject Terms: GENE expression, MYELOMA proteins, METHYLATION, CANCER patients, CHROMOSOMAL translocation

The Splicing Factor Prp43p, a DEAH Box ATPase, Functions in Ribosome Biogenesis.

Authors: Leeds, Nina B.^1,2, Small, Eliza C.³, Hiley, Shawna L.⁴, Hughes, Timothy R.^4,5, Staley, Jonathan P.¹ jstaley@uchicago.edu

Source: Molecular & Cellular Biology. Jan2006, Vol. 26 Issue 2, p12-12. 1p.

Subject Terms: *ORIGIN of life, *GENETIC regulation, *RNA splicing, *RNA, *RIBOSOMES