Optimized platform for automated glycan assembly

Authors: Danglad-Flores, José, Sletten, Eric T., Reuber, Emelie E., Bienert, Klaus, Riegler, Hans, Seeberger, Peter H.

Source: In Device 18 October 2024 2(10)

On resin synthesis of sulfated oligosaccharidesElectronic supplementary information (ESI) available. See DOI: 10.1039/d1sc06063e

Authors: Tyrikos-Ergas, Theodore, Sletten, Eric T., Huang, Jhih-Yi, Seeberger, Peter H., Delbianco, Martina

Source: Chemical science. 13(7):2115-2120

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100141077985.0x000001&indx=1&recIds=ETOCvdc_100141077985.0x000001

VaporSPOT: Parallel Synthesis of Oligosaccharides on Membranes

Authors: Tsouka, Alexandra, Dallabernardina, Pietro, Mende, Marco, Sletten, Eric T., Leichnitz, Sabrina, Bienert, Klaus, Le Mai Hoang, Kim, Seeberger, Peter H., Loeffler, Felix F.

Source: Journal of the American Chemical Society. 144(43):19832-19837

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN630587807&indx=1&recIds=ETOCRN630587807

Heparan Sulfate Mimicking Glycopolymer Prevents Pancreatic β Cell Destruction and Suppresses Inflammatory Cytokine Expression in Islets under the Challenge of Upregulated Heparanase

Authors: Loka, Ravi S., Song, Zhenfeng, Sletten, Eric T., Kayal, Yasmin, Vlodavsky, Israel, Zhang, Kezhong, Nguyen, Hien M.

Source: ACS chemical biology. 17(6):1387-1400

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN629559600&indx=1&recIds=ETOCRN629559600

Expedited synthesis of mannose-6-phosphate containing oligosaccharides

Authors: Sletten, Eric T., Danglad-Flores, José, Leichnitz, Sabrina, Abragam Joseph, A., Seeberger, Peter H.

Source: In Carbohydrate Research January 2022 511

A Synthetic Oligosaccharide Resembling Francisella tularensis Strain 15 O‐Antigen Capsular Polysaccharide as a Lead for Tularemia Diagnostics and Therapeutics.

Authors: Pradhan, Kabita¹, Reuber, Emelie E.^1,2, Sletten, Eric T.¹, Tomaso, Herbert³, Seeberger, Peter H.^1,2, Peter.Seeberger@mpikg.mpg.de

Source: Angewandte Chemie; 1/21/2025, Vol. 137 Issue 4, p1-7, 7p

Microwave-Assisted Automated Glycan Assembly

Authors: Danglad-Flores, José, Leichnitz, Sabrina, Sletten, Eric T., Joseph, A. Abragam, Bienert, Klaus, Le Mai Hoang, Kim, Seeberger, Peter H.

Source: Journal of the American Chemical Society. 143(23):8893-8901

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN626850467&indx=1&recIds=ETOCRN626850467

Enabling Technologies in Carbohydrate Chemistry: Automated Glycan Assembly, Flow Chemistry and Data Science

Authors: Lin, Mei‐Huei, Wolf, Jakob B., Sletten, Eric T., Cambié, Dario, Danglad‐Flores, José, Seeberger, Peter H.

Source: Chembiochem. 24(4)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100173628716.0x000001&indx=1&recIds=ETOCvdc_100173628716.0x000001

Real-time monitoring of solid-phase peptide synthesis using a variable bed flow reactorElectronic supplementary information (ESI) available. See DOI: 10.1039/c9cc08421e

Authors: Sletten, Eric T., Nuño, Manuel, Guthrie, Duncan, Seeberger, Peter H.

Source: Chemical communications. 55(97):14598-14601

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100093625410.0x000001&indx=1&recIds=ETOCvdc_100093625410.0x000001

Parametric Analysis of Donor Activation for Glycosylation Reactions.

Authors: Lin, Mei‐Huei^1,2, Kuo, Yan‐Ting^1,2,3, Danglad‐Flores, José¹, Sletten, Eric T.¹, Seeberger, Peter H.^1,2, Peter.Seeberger@mpikg.mpg.de

Source: Chemistry - A European Journal; 5/28/2024, Vol. 30 Issue 30, p1-7, 7p

Towards a Systematic Understanding of the Influence of Temperature on Glycosylation Reactions

Authors: Tuck, Owen T., Sletten, Eric T., Danglad‐Flores, José, Seeberger, Peter H.

Source: Angewandte Chemie international edition. 61(15)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100159760858.0x000001&indx=1&recIds=ETOCvdc_100159760858.0x000001

Zu einem Systematischen Verständnis des Einflusses der Temperatur auf Glykosylierungsreaktionen

Authors: Tuck, Owen T., Sletten, Eric T., Danglad‐Flores, José, Seeberger, Peter H.

Source: Angewandte Chemie. 134(15)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100157728252.0x000001&indx=1&recIds=ETOCvdc_100157728252.0x000001

Utilization of bench-stable and readily available nickel(II) triflate for access to 1,2-cis-2-aminoglycosides

Authors: Sletten, Eric T., Ramadugu, Sai Kumar, Nguyen, Hien M.

Source: In Carbohydrate Research 29 November 2016 435:195-207

Synthesis of a heparan sulfate tetrasaccharide using automated glycan assembly.

Authors: Pongener, Imlirenla, Sletten, Eric T., Danglad-Flores, José, Seeberger, Peter H., Miller, Gavin J.

Source: Organic & Biomolecular Chemistry; 2/21/2024, Vol. 22 Issue 7, p1395-1399, 5p

Glycosidase Inhibition by Multivalent Presentation of Heparan Sulfate Saccharides on Bottlebrush Polymers

Authors: Sletten, Eric T., Loka, Ravi S., Yu, Fei, Nguyen, Hien M.

Source: Biomacromolecules. 18(10):3387-3399

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN632282757&indx=1&recIds=ETOCRN632282757

Utilization of bench-stable and readily available nickel(II) triflate for access to 1, 2-cis-2-aminoglycosides

Authors: Sletten, Eric T., Ramadugu, Sai Kumar, Nguyen, Hien M.

Source: Carbohydrate research. 435:195-207

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100037460010.0x000001&indx=1&recIds=ETOCvdc_100037460010.0x000001

Phosphates as Assisting Groups in Glycan Synthesis.

Authors: Sletten, Eric T., Fittolani, Giulio, Hribernik, Nives, Dal Colle, Marlene C. S., Seeberger, Peter H., Delbianco, Martina

Source: ACS Central Science; 1/24/2024, Vol. 10 Issue 1, p138-142, 5p

Heparan Sulfate-Mimicking Glycopolymers Bind SARS-CoV‑2 Spike Protein in a Length- and Sulfation Pattern-Dependent Manner.

Authors: Abdulsalam, Hawau, Li, Jiayi, Loka, Ravi S., Sletten, Eric T., Nguyen, Hien M.

Source: ACS Medicinal Chemistry Letters; 10/12/2023, Vol. 14 Issue 10, p1411-1418, 8p

Visible-Light-Mediated Oxidative Debenzylation Enables the Use of Benzyl Ethers as Temporary Protecting Groups.

Authors: Cavedon, Cristian, Sletten, Eric T., Madani, Amiera, Niemeyer, Olaf, Seeberger, Peter H., Pieber, Bartholomäus

Source: Organic Letters; 1/15/2021, Vol. 23 Issue 2, p514-518, 5p

Synthesis of a polymerizable, bivalent glycan mimetic of the HIV envelope spike gp120

Authors: Sletten, Eric T., Svec, Riley L., Nguyen, Hien M.

Source: In Tetrahedron Letters 3 June 2015 56(23):3473-3476