Targeting skeletal interoception: a novel mechanistic insight into intervertebral disc degeneration and pain management

Authors: Houcheng Zhu, JianHang Ren, Xiangjin Wang, Wenjing Qin, Yong Xie

Source: Journal of Orthopaedic Surgery and Research, Vol 20, Iss 1, Pp 1-19 (2025)

Subject Terms: Intervertebral disc degeneration, Interception, Skeletal interoception, Prostaglandin E2, Nuclear factor kappa B, Wnt/β-catenin, Orthopedic surgery, RD701-811, Diseases of the musculoskeletal system, RC925-935

File Description: electronic resource

Relation: https://doaj.org/toc/1749-799X

Access URL: https://doaj.org/article/9e89359289644a658b16854b6c28c88f

Unloading‐Induced Skeletal Interoception Alters Hypothalamic Signaling to Promote Bone Loss and Fat Metabolism

Authors: Qiaoyue Guo, Ningrong Chen, Kalp Patel, Mei Wan, Junying Zheng, Xu Cao

Source: Advanced Science, Vol 10, Iss 35, Pp n/a-n/a (2023)

Subject Terms: bone metabolism, microgravity, neuropeptide Y (NPY), skeletal interoception, tyrosine hydroxylase (TH), Science

File Description: electronic resource

Relation: https://doaj.org/toc/2198-3844

Access URL: https://doaj.org/article/44664900c8a94316ab269283196a47a2