The molecular epidemiology of respiratory syncytial virus in Ontario, Canada from 2022–2024 using a custom whole genome sequencing assay and analytics package

Authors: Wong, Henry ^{a, b, c, ⁎}, Sjaarda, Calvin P. ^{a, b, c}, Rand, Brittany ^c, Roberts, Drew ^c, Tozer, Kyla ^{d, e}, Fattouh, Ramzi ^{f, g}, Kozak, Robert ^{g, h}, Sheth, Prameet M. ^{a, b, c, d}

Source: In Journal of Clinical Virology February 2025 176

Protease-Induced Excitation of Dorsal Root Ganglion Neurons in Response to Acute Perturbation of the Gut Microbiota Is Associated With Visceral and Somatic Hypersensitivity

Authors: Baker, Corey C., Sessenwein, Jessica L., Wood, Hannah M., Yu, Yang, Tsang, Quentin, Alward, Taylor A., Jimenez Vargas, Nestor N., Omar, Amal Abu, McDonnel, Abby, Segal, Julia P., Sjaarda, Calvin P., Bunnett, Nigel W., Schmidt, Brian L., Caminero, Alberto, Boev, Nadejda, Bannerman, Courtney A., Ghasemlou, Nader, Sheth, Prameet M., Vanner, Stephen J., Reed, David E., Lomax, Alan E.

Source: In Cellular and Molecular Gastroenterology and Hepatology 2024 18(4)

Colloidal structure of honey and its influence on antibacterial activity

Authors: Brudzynski, Katrina, Sjaarda, Calvin P.

Source: Comprehensive reviews in food science and food safety. 20(2):2063-2080

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100117510322.0x000001&indx=1&recIds=ETOCvdc_100117510322.0x000001

Changes in social environment impact primate gut microbiota composition.

Authors: Pearce, Colleen S., Bukovsky, Danielle, Douchant, Katya, Katoch, Abhay, Greenlaw, Jill, Gale, Daniel J., Nashed, Joseph Y., Brien, Don, Kuhlmeier, Valerie A., Sabbagh, Mark A., Blohm, Gunnar, De Felice, Fernanda G., Pare, Martin, Cook, Douglas J., Scott, Stephen H., Munoz, Douglas P., Sjaarda, Calvin P., Tusche, Anita, Sheth, Prameet M., Winterborn, Andrew

Source: Animal Microbiome; 11/13/2024, Vol. 6 Issue 1, p1-15, 15p

Subject Terms: SOCIAL impact, SOCIAL history, GUT microbiome, WELL-being, SOCIAL change

Relationship of family history conditions and early signs of autism spectrum disorder in low and high-risk infants

Authors: Feldman, Maurice A., Azzano, Alicia, Ward, Rebecca A., Hudson, Melissa, Sjaarda, Calvin P., Liu, Xudong

Source: In Research in Autism Spectrum Disorders September 2019 65:25-33

Homozygosity for the 10-repeat dopamine transporter (DAT1) allele is associated with reduced EEG response in males with ASD

Authors: Sjaarda, Calvin P., Sabbagh, Mark, Wood, Shalandra, Ward-King, Jessica, McNaughton, Amy J.M., Hudson, Melissa L., Tao, Mingda, Ayub, Muhammad, Liu, Xudong

Source: In Research in Autism Spectrum Disorders April 2019 60:25-35

Evaluation of 5 Polymerase Chain Reaction Assays for the Detection of Mpox Virus.

Authors: Fattouh, Ramzi, Boissinot, Karel, Jeong, Esther, Mendlowitz, Andrew B, Sjaarda, Calvin P, Wong, Henry, Kozak, Robert, Sheth, Prameet M, Matukas, Larissa M

Source: Journal of Infectious Diseases; 2024 Supplement, Vol. 229, pS156-S162, 7p

Subject Terms: MONKEYPOX, POLYMERASE chain reaction, DETECTION limit, WHOLE genome sequencing, MEDICAL microbiology

Geographic Terms: ONTARIO

Phylogenomics reveals viral sources, transmission, and potential superinfection in early-stage COVID-19 patients in Ontario, Canada.

Authors: Sjaarda, Calvin P.^1,2 calvin.sjaarda@queensu.ca, Rustom, Nazneen^2,3, Evans, Gerald A.^4,5,6, Huang, David⁷, Perez-Patrigeon, Santiago⁴, Hudson, Melissa L.^1,2, Wong, Henry⁸, Sun, Zhengxin⁷, Guan, T. Hugh⁹, Ayub, Muhammad^2,3, Soares, Claudio N.^1,2, Colautti, Robert I.⁷, Sheth, Prameet M.^5,6,8,10

Source: Scientific Reports. 2/12/2021, Vol. 11 Issue 1, p1-9. 9p.

Subject Terms: *COVID-19, *SUPERINFECTION, *PHYLOGENY, *VIRAL genomes

Geographic Terms: ONTARIO

Comparison of SARS-CoV-2 Viral Loads in the Nasal Mucosa of Patients Infected With BA.1, BA.2, or BA.5 Omicron Lineages.

Authors: Tozer, Kyla^1,2 (AUTHOR), Sjaarda, Calvin P^3,4 (AUTHOR), Moslinger, Emily^1,3 (AUTHOR), Wong, Henry⁴ (AUTHOR), Mubareka, Samira⁵ (AUTHOR), Maguire, Finlay⁵ (AUTHOR), Fattouh, Ramzi⁶ (AUTHOR), Brabant-Kirwan, Danielle⁷ (AUTHOR), Kozak, Robert^5,8,9 (AUTHOR), Sheth, Prameet M^1,2,3,4 (AUTHOR) ps70@queensu.ca

Source: Open Forum Infectious Diseases. Dec2022, Vol. 9 Issue 12, p1-5. 5p.

Subject Terms: *NASAL mucosa, *VIRAL load, *SARS-CoV-2 Omicron variant, *SARS-CoV-2, *VIRUS diseases

Emergence of a mutation in the nucleocapsid gene of SARS-CoV-2 interferes with PCR detection in Canada.

Authors: Isabel, Sandra, Abdulnoor, Mariana, Boissinot, Karel, Isabel, Marc R., de Borja, Richard, Zuzarte, Philip C., Sjaarda, Calvin P., R. Barker, Kevin, Sheth, Prameet M., Matukas, Larissa M., Gubbay, Jonathan B., McGeer, Alisson J., Mubareka, Samira, Simpson, Jared T., Fattouh, Ramzi

Source: Scientific Reports; 6/27/2022, Vol. 12 Issue 1, p1-7, 7p

Subject Terms: SARS-CoV-2, MOLECULAR probes, CANADIAN provinces

Geographic Terms: CANADA

Induction of lcc2 expression and activity by A garicus bisporus provides defence against T richoderma aggressivum toxic extracts.

Authors: Sjaarda, Calvin P.¹, Abubaker, Kamal S.¹, Castle, Alan J.¹

Source: Microbial Biotechnology. Sep2015, Vol. 8 Issue 6, p918-929. 12p.

Subject Terms: *CULTIVATED mushroom, *TRICHODERMA, *LACCASE, *TOXIN metabolism, *GENETIC transcription, *FUNGI

Temporal Dynamics and Evolution of SARS-CoV-2 Demonstrate the Necessity of Ongoing Viral Genome Sequencing in Ontario, Canada.

Authors: Sjaarda, Calvin P., Guthrie, Jennifer L., Mubareka, Samira, Simpson, Jared T., Hamelin, Bettina, Wong, Henry, Mortimer, Leanne, Slinger, Robert, McArthur, Andrew G., Desjardins, Marc, McGeer, Allison, Mazzulli, Tony, Douchant, Katya, Brabant-Kirwan, Danielle, Fattouh, Ramzi, Campigotto, Aaron, Patel, Samir N., Fittipaldi, Nahuel, Colautti, Robert I., Shethi, Prameet M.

Source: MSphere; Jun2021, Vol. 6 Issue 3, p1-9, 9p

De novo duplication on Chromosome 19 observed in nuclear family displaying neurodevelopmental disorders.

Authors: Sjaarda, Calvin P., Kaiser, Beatrice, McNaughton, Amy J. M., Hudson, Melissa L., Harris-Lowe, Liam, Lou, Kyle, Guerin, Andrea, Muhammad Ayub, Xudong Liu

Source: Cold Spring Harbor Molecular Case Studies; 2020, Vol. 6 Issue 3, p1-17, 17p

Subject Terms: NEUROLOGICAL disorders, ETIOLOGY of diseases, POLYMERASE chain reaction, GENETIC transcription, IMMUNE response, TRANSCRIPTOMES

Genome-wide detection of tandem DNA repeats that are expanded in autism

Authors: Trost, Brett, Engchuan, Worrawat, Nguyen, Charlotte M., Thiruvahindrapuram, Bhooma, Dolzhenko, Egor, Backstrom, Ian, Mirceta, Mila, Mojarad, Bahareh A., Yin, Yue, Dov, Alona, Chandrakumar, Induja, Prasolava, Tanya, Shum, Natalie, Hamdan, Omar, Pellecchia, Giovanna, Howe, Jennifer L., Whitney, Joseph, Klee, Eric W., Baheti, Saurabh, Amaral, David G., Anagnostou, Evdokia, Elsabbagh, Mayada, Fernandez, Bridget A., Hoang, Ny, Lewis, M. E. Suzanne, Liu, Xudong, Sjaarda, Calvin, Smith, Isabel M., Szatmari, Peter, Zwaigenbaum, Lonnie, Glazer, David, Hartley, Dean, Stewart, A. Keith, Eberle, Michael A., Sato, Nozomu, Pearson, Christopher E., Scherer, Stephen W., Yuen, Ryan K. C.

Source: Nature; October 2020, Vol. 586 Issue: 7827 p80-86, 7p

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Exome sequencing identifies de novo splicing variant in XRCC6in sporadic case of autism

Authors: Sjaarda, Calvin P., Wood, Shalandra, McNaughton, Amy J. M., Taylor, Sarah, Hudson, Melissa L., Liu, Xudong, Guerin, Andrea, Ayub, Muhammad

Source: Journal of Human Genetics; March 2020, Vol. 65 Issue: 3 p287-296, 10p

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