Discovery of new inhibitors of nuclease MRE11

Authors: Nikulenkov, Fedor ^a, Carbain, Benoit ^{a, d}, Biswas, Raktim ^a, Havel, Stepan ^{b, d}, Prochazkova, Jana ^a, Sisakova, Alexandra ^a, Zacpalova, Magdalena ^a, Chavdarova, Melita ^a, Marini, Victoria ^a, Vsiansky, Vit ^a, Weisova, Veronika ^a, Slavikova, Kristina ^a, Biradar, Dhanraj ^{b, d}, Khirsariya, Prashant ^{b, d}, Vitek, Marco ^d, Sedlak, David ^e, Bartunek, Petr ^e, Daniel, Lukas ^{b, c}, Brezovsky, Jan ^{b, c}, Damborsky, Jiri ^{b, c}, Paruch, Kamil ^{b, d, ⁎⁎}, Krejci, Lumir ^{a, f, ⁎}

Source: In European Journal of Medicinal Chemistry 5 March 2025 285

Withdrawal: Cooperativity of Mus81·Mms4 with Rad54 in the resolution of recombination and replication intermediates

Authors: Matulova, Petra, Marini, Victoria, Burgess, Rebecca C., Sisakova, Alexandra, Kwon, Youngho, Rothstein, Rodney, Sung, Patrick, Krejci, Lumir

Source: In Journal of Biological Chemistry October 2024 300(10)

Role of PCNA and RFC in promoting Mus81-complex activity

Authors: Sisakova, Alexandra, Altmannova, Veronika, Sebesta, Marek, Krejci, Lumir

Source: BMC biology. 15(1):1-17

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100143635991.0x000001&indx=1&recIds=ETOCvdc_100143635991.0x000001

Local regulation of the Srs2 helicase by the SUMO-like domain protein Esc2 promotes recombination at sites of stalled replication

Authors: Urulangodi, Madhusoodanan, Sebesta, Marek, Menolfi, Demis, Szakal, Barnabas, Sollier, Julie, Sisakova, Alexandra, Krejci, Lumir, Branzei, Dana

Source: Genes & development. 29(19):2067-2080

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN603264744&indx=1&recIds=ETOCRN603264744

A residue of motif III positions the helicase domains of motor subunit HsdR in restriction-modification enzyme EcoR124I

Authors: Sinha, Dhiraj, Bialevich, Vitali, Shamayeva, Katsiaryna, Guzanova, Alena, Sisakova, Alexandra, Csefalvay, Eva, Reha, David, Krejci, Lumir, Carey, Jannette, Weiserova, Marie, Ettrich, Rüdiger

Source: Journal of molecular modeling. 24(7)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100118508663.0x000001&indx=1&recIds=ETOCvdc_100118508663.0x000001

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Cooperativity of Mus81·Mms4 with Rad54 in the Resolution of Recombination and Replication Intermediates

Authors: Matulova, Petra, Marini, Victoria, Burgess, Rebecca C., Sisakova, Alexandra, Kwon, Youngho, Rothstein, Rodney, Sung, Patrick, Krejci, Lumir

Source: In Journal of Biological Chemistry 20 March 2009 284(12):7733-7745

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Srs2 mediates PCNA-SUMO-dependent inhibition of DNA repair synthesis.

Authors: Burkovics, Peter, Sebesta, Marek, Sisakova, Alexandra, Plault, Nicolas, Szukacsov, Valeria, Robert, Thomas, Pinter, Lajos, Marini, Victoria, Kolesar, Peter, Haracska, Lajos, Gangloff, Serge, Krejci, Lumir

Source: EMBO Journal; 3/6/2013, Vol. 32 Issue 5, p742-755, 14p, 1 Black and White Photograph, 2 Diagrams, 4 Graphs

Subject Terms: PROLIFERATING cell nuclear antigen, DNA repair, DNA damage, DNA replication, SMALL ubiquitin-related modifier proteins, GENETIC regulation, BIOSYNTHESIS, ENZYME inhibitors