Cardiovascular impact of near complete estrogen deprivation in premenopausal women with breast cancer: The CROWN study

Authors: Thomas, Alexandra, O'Connell, Nathaniel S., Douglas, Emily, Hatcher, Sarah, Park, Carolyn J., Dent, Susan, Ansley, Katherine, Klem, Igor, Bansal, Rani, Westbrook, Kelly, Hundley, W. Gregory, Bottinor, Wendy, Hackney, Mary Helen, Richardson, Karl M., Sirkisoon, Sherona R., D'Agostino, Ralph B., Jr., Jordan, Jennifer H.

Source: In American Heart Journal January 2024 267:33-43

Breast cancer extracellular vesicles-derived miR-1290 activates astrocytes in the brain metastatic microenvironment via the FOXA2→CNTF axis to promote progression of brain metastases

Authors: Sirkisoon, Sherona R., Wong, Grace L., Aguayo, Noah R., Doheny, Daniel L., Zhu, Dongqin, Regua, Angelina T., Arrigo, Austin, Manore, Sara G., Wagner, Calvin, Thomas, Alexandra, Singh, Ravi, Xing, Fei, Jin, Guangxu, Watabe, Kounosuke, Lo, Hui-Wen

Source: In Cancer Letters 1 August 2022 540

TGLI1 transcription factor mediates breast cancer brain metastasis via activating metastasis-initiating cancer stem cells and astrocytes in the tumor microenvironment

Authors: Sirkisoon, Sherona R., Carpenter, Richard L., Rimkus, Tadas, Doheny, Daniel, Zhu, Dongqin, Aguayo, Noah R., Xing, Fei, Chan, Michael, Ruiz, Jimmy, Metheny-Barlow, Linda J., Strowd, Roy, Lin, Jiayuh, Regua, Angelina T., Arrigo, Austin, Anguelov, Marlyn, Pasche, Boris, Debinski, Waldemar, Watabe, Kounosuke, Lo, Hui-Wen

Source: Oncogene. 39(1):64-78

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100193644972.0x000001&indx=1&recIds=ETOCvdc_100193644972.0x000001

An FDA-Approved Antifungal, Ketoconazole, and Its Novel Derivative Suppress tGLI1-Mediated Breast Cancer Brain Metastasis by Inhibiting the DNA-Binding Activity of Brain Metastasis-Promoting Transcription Factor tGLI1.

Authors: Doheny, Daniel, Manore, Sara, Sirkisoon, Sherona R., Zhu, Dongqin, Aguayo, Noah R., Harrison, Alexandria, Najjar, Mariana, Anguelov, Marlyn, Cox, Anderson O'Brien, Furdui, Cristina M., Watabe, Kounosuke, Hollis, Thomas, Thomas, Alexandra, Strowd, Roy, Lo, Hui-Wen

Source: Cancers; Sep2022, Vol. 14 Issue 17, p4256, 21p

Subject Terms: KETOCONAZOLE, DRUG approval, ANIMAL experimentation, NEOVASCULARIZATION, METASTASIS, BRAIN tumors, CELL proliferation, TRANSCRIPTION factors, MOLECULAR structure, CELL lines, BREAST tumors

Company/Entity: UNITED States. Food & Drug Administration

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Correction: Interaction between STAT3 and GLI1/tGLI1 oncogenic transcription factors promotes the aggressiveness of triple-negative breast cancers and HER2-enriched breast cancer

Authors: Sirkisoon, Sherona R., Carpenter, Richard L., Rimkus, Tadas, Anderson, Ashley, Harrison, Alexandria, Lange, Allison M., Jin, Guangxu, Watabe, Kounosuke, Lo, Hui-Wen

Source: Oncogene; 20240101, Issue: Preprints p1-1, 1p

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Correction: TGLI1 transcription factor mediates breast cancer brain metastasis via activating metastasis-initiating cancer stem cells and astrocytes in the tumor microenvironment

Authors: Sirkisoon, Sherona R., Carpenter, Richard L., Rimkus, Tadas, Doheny, Daniel, Zhu, Dongqin, Aguayo, Noah R., Xing, Fei, Chan, Michael, Ruiz, Jimmy, Metheny-Barlow, Linda J., Strowd, Roy, Lin, Jiayuh, Regua, Angelina T., Arrigo, Austin, Anguelov, Marlyn, Pasche, Boris, Debinski, Waldemar, Watabe, Kounosuke, Lo, Hui-Wen

Source: Oncogene; March 2021, Vol. 40 Issue: 12 p2338-2338, 1p