Sinomenine hydrochloride improves DSS-induced colitis in mice through inhibition of the Notch signaling pathway

Authors: Linxia Xu, Wei Liu, Xixiang Huang, Tong Sun, Letian Mei, Man Liu, Zhi Ren, Meng Wang, Hailun Zheng, Qiangwu Wang, Dapeng Li, Qizhi Wang, Xiquan Ke

Source: BMC Gastroenterology, Vol 24, Iss 1, Pp 1-12 (2024)

Subject Terms: Ulcerative colitis, Sinomenine hydrochloride, Notch signaling pathway, Disease activity index, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: https://doaj.org/toc/1471-230X

Access URL: https://doaj.org/article/85fc9420c8fa4805bfb33e5faf9d3e61

Graphene oxide quantum dots-loaded sinomenine hydrochloride nanocomplexes for effective treatment of rheumatoid arthritis via inducing macrophage repolarization and arresting abnormal proliferation of fibroblast-like synoviocytes

Authors: Ye Lin, Yuanyuan Tang, Ouyang Yi, Junping Zhu, Zhaoli Su, Gejing Li, Hua Zhou, Liang Liu, Bin Liu, Xiong Cai

Source: Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-22 (2024)

Subject Terms: Sinomenine hydrochloride, Nanomedicine, Rheumatoid arthritis, Fibroblast-like synoviocytes, Macrophage repolarization, Biotechnology, TP248.13-248.65, Medical technology, R855-855.5

File Description: electronic resource

Relation: https://doaj.org/toc/1477-3155

Access URL: https://doaj.org/article/214018d85a3d46c698ba0066b3dc744e

Phaseolus lunatusL. polysaccharide microneedles loaded with sinomenine hydrochloride for synergistic rheumatoid arthritis management and analgesia

Authors: Feng, Yunjia ^a, Tang, Yan ^a, Hu, Jingwen ^a, Chen, Can ^a, Zhong, Guozhi ^a, Xiang, Caiqin ^b, Chen, Na ^c, Bian, Jinhui ^{a, ∗}, Shi, Sanjun ^{a, ∗}, Zhang, Yinsu ^{b, ∗}

Source: In International Journal of Biological Macromolecules May 2025 306 Part 3

Sinomenine Hydrochloride Protects IgA Nephropathy Through Regulating Cell Growth and Apoptosis of T and B Lymphocytes

Authors: Li JJ, Li L, Li S, Tang XY, Sun HF, Liu JX

Source: Drug Design, Development and Therapy, Vol Volume 18, Pp 1247-1262 (2024)

Subject Terms: sinomenine hydrochloride, cell cycle, apoptosis, igan, jurkat t and ramos b cells, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.dovepress.com/sinomenine-hydrochloride-protects-iga-nephropathy-through-regulating-c-peer-reviewed-fulltext-article-DDDT; https://doaj.org/toc/1177-8881

Access URL: https://doaj.org/article/6f88d553b2d245b383c9a2f5cc355af7

Prediction of drug dissolution from sustained-release pellet by a portable near-infrared spectrometer

Authors: Wu, Sijun ^{a, b, 1}, Yang, Yinglian ^{a, 1}, Wang, Li ^a, Jia, Chaoliang ^a, Guan, Zhiqi ^a, Chen, Haiyang ^a, Zhu, Yadong ^{d, ⁎⁎}, Li, Wenlong ^{a, b, c, ⁎}

Source: In Journal of Drug Delivery Science and Technology December 2024 102 Part B

N-demethylsinomenine metabolite and its prototype sinomenine activate mast cells via MRGPRX2 and aggravate anaphylaxis

Authors: Youfa Qin, Yihan Huang, Xiaolan Ji, Ling Gong, Shiqiong Luo, Jiapan Gao, Rui Liu, Tao Zhang

Source: Frontiers in Pharmacology, Vol 15 (2024)

Subject Terms: N-demethylsinomenine, sinomenine hydrochloride, MRGPRX2, anaphylaxis, synergistically, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2024.1389761/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/643edd3e18774cd6844052e91bd5d2be

Separation, Extraction and Purification of Natural Products from Plants

Contributors: Gong, Xingchu

Subject Terms: azide, cilostazol, COVID-19, genotoxic impurity, validation, LLE, ethanol precipitation, loss of active ingredients, mixing condition indicator, micromesh mixer, Caulis sinomenii, microfiltration, ultrafiltration, sinomenine hydrochloride, separation and purification, Phyllanthus urinaria L., ellagic acid, mechanochemical-assisted extraction, macroporous adsorption resin, compositional monosaccharides, HPLC–ELSD/PDA combined with HPSEC–MALLS–RID, molecular weight, quality markers (Q-marker), red ginseng polysaccharides, Xiaochaihu (XCH) formula, preparations, quality control, standard, 4-aryl-3,4-dihydropyrimidin-2(1H)-ones, teicoplanin aglycone, chiral HPLC, enantioselectivity, molecular docking, molecular dynamics, Radix Angelicae sinensis, volatile oil, Box–Behnken design, steam distillation, extraction kinetics, design space, dill, Anethum graveolens L., essential oil, Neofusicoccum parvum, antifungal mechanism, near-infrared spectroscopy, Astragali radix, alcohol precipitation, accuracy profile, Vis-NIR spectroscopy, Ginkgo biloba L. leaves, in-line analysis, column chromatographic elution, consistency evaluation, multivariate statistical process control (MSPC), quality by design, Xiaochaihu capsule, quantitative chromatographic fingerprint, definitive screening design, Plackett–Burman, Forsythia suspensa, Lonicera japonica, Research and information: general, Chemistry, Analytical chemistry

File Description: application/octet-stream

Access URL: https://directory.doabooks.org/handle/20.500.12854/128561
https://mdpi.com/books/pdfview/book/8010

Improved up-and-down procedure for acute toxicity measurement with reliable LD50 verified by typical toxic alkaloids and modified Karber method

Authors: Yan-Yu Zhang, Yu-Feng Huang, Jie Liang, Hua Zhou

Source: BMC Pharmacology and Toxicology, Vol 23, Iss 1, Pp 1-11 (2022)

Subject Terms: Acute toxicity, Improved up-and-down procedure, Median lethal dose, Modified Karber method, Nicotine, Sinomenine hydrochloride, Therapeutics. Pharmacology, RM1-950, Toxicology. Poisons, RA1190-1270

File Description: electronic resource

Relation: https://doaj.org/toc/2050-6511

Access URL: https://doaj.org/article/6817f3f2d8cb4b31a0e9c5f19015686c

Effects of Tumor-Derived DNA on CXCL12-CXCR4 and CCL21-CCR7 Axes of Hepatocellular Carcinoma Cells and the Regulation of Sinomenine Hydrochloride

Authors: Conghuan Shen, Jianhua Li, Ruidong Li, Zhenyu Ma, Yifeng Tao, Quanbao Zhang, Zhengxin Wang

Source: Frontiers in Oncology, Vol 12 (2022)

Subject Terms: hepatic carcinoma, CXCL12-CXCR4, CCL21-CCR7, sinomenine hydrochloride, tumor-derived DNA, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2022.901705/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/231adae24b834500b533ee1be74fef62

Sinomenine Hydrochloride Can Ameliorate Benign Prostatic Hyperplasia by Lowering the 5α-Reductase 2 Level and Regulating the Balance between the Proliferation and Apoptosis of Cells

Authors: Mao-Si Fan, Yue-Fei Xia, Rui-Han Ye, Ze-Rui Sun, Ming-Yue Wang, Meng-Fei An, Shao-Shi Zhang, Li-Juan Zhang, Yun-Li Zhao, Ze-Min Xiang, Jun Sheng

Source: Molecules, Vol 28, Iss 2, p 803 (2023)

Subject Terms: benign prostatic hyperplasia, sinomenine hydrochloride, 5α-reductase 2, apoptosis, PCNA, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/28/2/803; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/d18ae80a6b8140db83ea07e8ac6dd670

Sinomenine Hydrochloride Ameliorates Fish Foodborne Enteritis via α7nAchR-Mediated Anti-Inflammatory Effect Whilst Altering Microbiota Composition

Authors: Jiayuan Xie, Ming Li, Weidong Ye, Junwei Shan, Xuyang Zhao, You Duan, Yuhang Liu, Bruno Hamish Unger, Yingyin Cheng, Wanting Zhang, Nan Wu, Xiao-Qin Xia

Source: Frontiers in Immunology, Vol 12 (2021)

Subject Terms: SBMIE, zebrafish, sinomenine hydrochloride, α7nAChR, anti-inflammation, microbiota, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2021.766845/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/6307ceca52c24c70b20d162dac865e18

Synergic radiosensitization of sinomenine hydrochloride and radioiodine on human papillary thyroid carcinoma cells

Authors: Aomei Zhao, Jing Zhang, Yan Liu, Xi Jia, Xueni Lu, Qi Wang, Ting Ji, Lulu Yang, Jianjun Xue, Rui Gao, Yan Yu, Aimin Yang

Source: Translational Oncology, Vol 14, Iss 10, Pp 101172- (2021)

Subject Terms: Sinomenine hydrochloride, Iodine-131, Papillary thyroid carcinoma cell, Radiosensitivity, Apoptosis, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1936523321001649; https://doaj.org/toc/1936-5233

Access URL: https://doaj.org/article/5b4b308ee8bd4a51b65839964320d844

Polyvinylpyrrolidone microneedles for localized delivery of sinomenine hydrochloride: preparation, release behavior of in vitro & in vivo, and penetration mechanism

Authors: Zixuan Shu, Yingji Cao, Yaotian Tao, Xiao Liang, Fangyuan Wang, Zhi Li, Zhenbao Li, Shuangying Gui

Source: Drug Delivery, Vol 27, Iss 1, Pp 642-651 (2020)

Subject Terms: sinomenine hydrochloride, dissolving microneedles, transdermal drug delivery system, microdialysis, fluorescent labeling, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://doaj.org/toc/1071-7544; https://doaj.org/toc/1521-0464

Access URL: https://doaj.org/article/f3ac71a3d58d453db888e1a404cb7e4d

Sinomenine hydrochloride exerts antitumor outcome in ovarian cancer cells by inhibition of long non-coding RNA HOST2 expression

Authors: Yuting Xu, Tao Jiang, Changhe Wang, Fei Wang

Source: Artificial Cells, Nanomedicine, and Biotechnology, Vol 47, Iss 1, Pp 4131-4138 (2019)

Subject Terms: Ovarian cancer, sinomenine hydrochloride, HOST2, cell viability, apoptosis, Biotechnology, TP248.13-248.65, Medical technology, R855-855.5

File Description: electronic resource

Relation: https://doaj.org/toc/2169-1401; https://doaj.org/toc/2169-141X

Access URL: https://doaj.org/article/7ad2de0a2b9b4ceebf872d89af96a2cc

Studies on the Separation and Purification of the Caulis sinomenii Extract Solution Using Microfiltration and Ultrafiltration

Authors: Xi Wang, Huimin Feng, Halimulati Muhetaer, Zuren Peng, Ping Qiu, Wenlong Li, Zheng Li

Source: Separations, Vol 8, Iss 10, p 185 (2021)

Subject Terms: Caulis sinomenii, microfiltration, ultrafiltration, sinomenine hydrochloride, separation and purification, Physics, QC1-999, Chemistry, QD1-999

File Description: electronic resource

Relation: https://www.mdpi.com/2297-8739/8/10/185; https://doaj.org/toc/2297-8739

Access URL: https://doaj.org/article/648aae9ec90f4a1281b02a43ecc66154

Controlled release of optimized electroporation enhances the transdermal efficiency of sinomenine hydrochloride for treating arthritis in vitro and in clinic

Authors: Feng S, Zhu L, Huang Z, Wang H, Li H, Zhou H, Lu L, Wang Y, Liu Z, Liu L

Source: Drug Design, Development and Therapy, Vol Volume 11, Pp 1737-1752 (2017)

Subject Terms: Electroporation, sinomenine hydrochloride, transdermal drug delivery, arthritis, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.dovepress.com/controlled-release-of-optimized-electroporation-enhances-the-transderm-peer-reviewed-article-DDDT; https://doaj.org/toc/1177-8881

Access URL: https://doaj.org/article/8aa8833f28374e17b4b22f69d2eddb90

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