Structural Basis of Transcription Inhibition by Fidaxomicin (Lipiarmycin A3)

Authors: Lin, Wei, Das, Kalyan, Degen, David, Mazumder, Abhishek, Duchi, Diego, Wang, Dongye, Ebright, Yon W., Ebright, Richard Y., Sineva, Elena, Gigliotti, Matthew, Srivastava, Aashish, Mandal, Sukhendu, Jiang, Yi, Liu, Yu, Yin, Ruiheng, Zhang, Zhening, Eng, Edward T., Thomas, Dennis, Donadio, Stefano, Zhang, Haibo, Zhang, Changsheng, Kapanidis, Achillefs N., Ebright, Richard H.

Source: In Molecular Cell 5 April 2018 70(1):60-71

Allosteric Effector ppGpp Potentiates the Inhibition of Transcript Initiation by DksA

Authors: Molodtsov, Vadim, Sineva, Elena, Zhang, Lu, Huang, Xuhui, Cashel, Michael, Ades, Sarah E., Murakami, Katsuhiko S.

Source: In Molecular Cell 1 March 2018 69(5):828-839

Themes and variations in gene regulation by extracytoplasmic function (ECF) sigma factors

Authors: Sineva, Elena, Savkina, Maria, Ades, Sarah E

Source: In Current Opinion in Microbiology April 2017 36:128-137

Interactions among Cytochromes P450 in Microsomal Membranes: OLIGOMERIZATION OF CYTOCHROMES P450 3A4, 3A5, AND 2E1 AND ITS FUNCTIONAL CONSEQUENCES

Authors: Davydov, Dmitri R., Davydova, Nadezhda Y., Sineva, Elena V., Halpert, James R.

Source: In Journal of Biological Chemistry 6 February 2015 290(6):3850-3864

A host‐derived chimeric peptide protects citrus against Huanglongbing without threatening the native microbial community of the phyllosphere.

Authors: Choi, Jeongyun, Basu, Supratim, Thompson, Abigail, Otto, Kristen, Sineva, Elena V., Kunta, Madhurababu, Gupta, Goutam, Trivedi, Pankaj

Source: Journal of Sustainable Agriculture & Environment; Dec2023, Vol. 2 Issue 4, p489-499, 11p

Peripheral Ligand-binding Site in Cytochrome P450 3A4 Located with Fluorescence Resonance Energy Transfer (FRET)

Authors: Davydov, Dmitri R., Rumfeldt, Jessica A.O., Sineva, Elena V., Fernando, Harshica, Davydova, Nadezhda Y., Halpert, James R.

Source: In Journal of Biological Chemistry 24 February 2012 287(9):6797-6809

New target for inhibition of bacterial RNA polymerase: ‘switch region’

Authors: Srivastava, Aashish, Talaue, Meliza, Liu, Shuang, Degen, David, Ebright, Richard Y, Sineva, Elena, Chakraborty, Anirban, Druzhinin, Sergey Y, Chatterjee, Sujoy, Mukhopadhyay, Jayanta, Ebright, Yon W, Zozula, Alex, Shen, Juan, Sengupta, Sonali, Niedfeldt, Rui Rong, Xin, Cai, Kaneko, Takushi, Irschik, Herbert, Jansen, Rolf, Donadio, Stefano, Connell, Nancy, Ebright, Richard H

Source: In Current Opinion in Microbiology 2011 14(5):532-543

Electron transfer in the complex of membrane-bound human cytochrome P450 3A4 with the flavin domain of P450BM-3: The effect of oligomerization of the heme protein and intermittent modulation of the spin equilibrium

Authors: Davydov, Dmitri R., Sineva, Elena V., Sistla, Srinivas, Davydova, Nadezhda Y., Frank, Daniel J., Sligar, Stephen G., Halpert, James R.

Source: In BBA - Bioenergetics 2010 1797(3):378-390

Constrained water access to the active site of cytochrome P450 from the piezophilic bacterium Photobacterium profundum

Authors: Sineva, Elena V., Davydov, Dmitri R.

Source: High pressure research. 30(4):466-474

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100112061624.0x000001&indx=1&recIds=ETOCvdc_100112061624.0x000001

Systematic Structure-Activity Analysis of Microcin J25

Authors: Pavlova, Olga, Mukhopadhyay, Jayanta, Sineva, Elena, Ebright, Richard H., Severinov, Konstantin ^**

Source: In Journal of Biological Chemistry 12 September 2008 283(37):25589-25595

Host-derived chimeric peptides clear the causative bacteria and augment host innate immunity during infection: A case study of HLB in citrus and fire blight in apple.

Authors: Basu, Supratim, Sineva, Elena, Nguyen, Liza, Sikdar, Narattam, Park, Sinev, Mikhail, Kunta, Madhurababu, Gupta, Goutam

Source: Frontiers in Plant Science; 12/23/2022, Vol. 13, p1-16, 16p

Subject Terms: IN vitro toxicity testing, PLANT diseases, CITRUS greening disease, PRODUCTION losses, PEPTIDES, DISEASE resistance of plants, CITRUS

The properties of Bacillus cereus hemolysin II pores depend on environmental conditions

Authors: Andreeva, Zhanna I., Nesterenko, Vladimir F., Fomkina, Maria G., Ternovsky, Vadim I., Suzina, Natalia E., Bakulina, Anastasia Yu, Solonin, Alexander S., Sineva, Elena V.

Source: In BBA - Biomembranes 2007 1768(2):253-263

Mutational derivatives of microcin J25

Purification and cytotoxic properties of Bacillus cereus hemolysin II

Authors: Andreeva, Zhanna I., Nesterenko, Vladimir F., Yurkov, Igor S., Budarina, Zhanna I., Sineva, Elena V., Solonin, Alexander S.

Source: In Protein Expression and Purification 2006 47(1):186-193

Cytochrome P450 from Photobacterium profundum SS9, a Piezophilic Bacterium, Exhibits a Tightened Control of Water Access to the Active Site.

Authors: Sineva, Elena V., Davydov, Dmitri R.

Source: Biochemistry; December 21 2010, Vol. 49 Issue 50, p10636-10646, 11p

Inhibition of Bacterial RNA Polymerase by Streptolydigin: Stabilization of a Straight-Bridge-Helix Active-Center Conformation

Authors: Tuske, Steven, Sarafianos, Stefan G., Wang, Xinyue, Hudson, Brian, Sineva, Elena, Mukhopadhyay, Jayanta, Birktoft, Jens J., Leroy, Olivier, Ismail, Sajida, Clark, Arthur D., Jr., Dharia, Chhaya, Napoli, Andrew, Laptenko, Oleg, Lee, Jookyung, Borukhov, Sergei, Ebright, Richard H. ^*, Arnold, Eddy ^*

Source: In Cell 26 August 2005 122(4):541-552

Backbone dynamics of Escherichia coli adenylate kinase at the extreme stages of the catalytic cycle studied by 15N NMR relaxation.

Authors: Shapiro, Yury E., Sinev, Michael A., Sineva, Elena V.

Source: Biochemistry; June 6 2000, Vol. 39 Issue 22, p6634-6644, 11p

Antibacterial Peptide Microcin J25 Inhibits Transcription by Binding within and Obstructing the RNA Polymerase Secondary Channel

Authors: Mukhopadhyay, Jayanta, Sineva, Elena, Knight, Jennifer, Levy, Ronald M., Ebright, Richard H. ^*

Source: In Molecular Cell 2004 14(6):739-751

Purification and characterization of hepatitis C virus non-structural protein 5A expressed in Escherichia coli

Authors: Huang, Luyun, Sineva, Elena V, Hargittai, Michele R.S, Sharma, Suresh D, Suthar, Mehul, Raney, Kevin D, Cameron, Craig E

Source: In Protein Expression and Purification 2004 37(1):144-153

Domain closure in adenylate kinase.

Authors: Sinev, Michael A., Sineva, Elena V., Ittah, Varda

Source: Biochemistry; May 21 1996, Vol. 35, p6425-6437, 13p