Tongue orthotopic xenografts to study fusion-negative rhabdomyosarcoma invasion and metastasis in live animals

Authors: Hammoudeh, Sarah M. ¹, Ng, Yeap ^{1, 2}, Wei, Bih-Rong ³, Madsen, Thomas D. ^{1, 4}, Yadav, Mukesh P. ^{1, 6}, Simpson, R. Mark ³, Weigert, Roberto ^{1, 2, 5, ∗}, Randazzo, Paul A. ^{1, 5, 7, ∗∗}

Source: In Cell Reports Methods 15 July 2024 4(7)

Drug combinations identified by high-throughput screening promote cell cycle transition and upregulate Smad pathways in myeloma

Authors: Peat, Tyler J., Gaikwad, Snehal M., Dubois, Wendy, Gyabaah-Kessie, Nana, Zhang, Shuling, Gorjifard, Sayeh, Phyo, Zaw, Andres, Megan, Hughitt, V. Keith, Simpson, R. Mark, Miller, Margaret A., Girvin, Andrew T., Taylor, Andrew, Williams, Daniel, D'Antonio, Nelson, Zhang, Yong, Rajagopalan, Adhithi, Flietner, Evan, Wilson, Kelli, Zhang, Xiaohu, Shinn, Paul, Klumpp-Thomas, Carleen, McKnight, Crystal, Itkin, Zina, Chen, Lu, Kazandijian, Dickran, Zhang, Jing, Michalowski, Aleksandra M., Simmons, John K., Keats, Jonathan, Thomas, Craig J., Mock, Beverly A.

Source: In Cancer Letters 1 August 2023 568

Inter-Institutional Partnerships to Develop Veterinarian—Investigators through the NIH Comparative Biomedical Scientist Training Program Benefit One Health Goals

Authors: Simpson, R. Mark, Hoover, Shelley B., Davis, Barbara J., Hickerson, John, Miller, Margaret A., Kiupel, Matti, Cullen, John M., Dwyer, Jennifer E., Wei, Bih-Rong, Rosol, Thomas J.

Source: Journal of veterinary medical education. 47(5):619-631

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN625976193&indx=1&recIds=ETOCRN625976193

Agreement in Histological Assessment of Mitotic Activity Between Microscopy and Digital Whole Slide Images Informs Conversion for Clinical Diagnosis

Authors: Wei, Bih-Rong, Halsey, Charles H., Hoover, Shelley B., Puri, Munish, Yang, Howard H., Gallas, Brandon D., Lee, Maxwell P., Chen, Weijie, Durham, Amy C., Dwyer, Jennifer E., Sánchez, Melissa D., Traslavina, Ryan P., Frank, Chad, Bradley, Charles, McGill, Lawrence D., Esplin, D. Glen, Schaffer, Paula A., Cramer, Sarah D., Lyle, L. Tiffany, Beck, Jessica, Buza, Elizabeth, Gong, Qi, Hewitt, Stephen M., Simpson, R. Mark ^*

Source: In Academic Pathology January-December 2019 6

Automated Computational Detection, Quantitation, and Mapping of Mitosis in Whole-Slide Images for Clinically Actionable Surgical Pathology Decision Support

Authors: Puri, Munish, Hoover, Shelley B., Hewitt, Stephen M., Wei, Bih-Rong, Adissu, Hibret Amare, Halsey, Charles H.C., Beck, Jessica, Bradley, Charles, Cramer, Sarah D., Durham, Amy C., Esplin, D. Glen, Frank, Chad, Lyle, L. Tiffany, McGill, Lawrence D., Sánchez, Melissa D., Schaffer, Paula A., Traslavina, Ryan P., Buza, Elizabeth, Yang, Howard H., Lee, Maxwell P., Dwyer, Jennifer E., Simpson, R. Mark ^*

Source: In Journal of Pathology Informatics January-December 2019 10(1)

CCL5 production in lung cancer cells leads to an altered immune microenvironment and promotes tumor development

Authors: Melese, Etienne S., Franks, Elizabeth, Cederberg, Rachel A., Harbourne, Bryant T., Shi, Rocky, Wadsworth, Brennan J., Collier, Jenna L., Halvorsen, Elizabeth C., Johnson, Fraser, Luu, Jennifer, Oh, Min Hee, Lam, Vivian, Krystal, Gerald, Hoover, Shelley B., Raffeld, Mark, Simpson, R. Mark, Unni, Arun M., Lam, Wan L., Lam, Stephen, Abraham, Ninan, Bennewith, Kevin L., Lockwood, William W.

Source: Oncoimmunology. 11(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100168532363.0x000001&indx=1&recIds=ETOCvdc_100168532363.0x000001

cFOS-SOX9 Axis Reprograms Bone Marrow-Derived Mesenchymal Stem Cells into Chondroblastic Osteosarcoma

Authors: He, Yunlong, Zhu, Wentao, Shin, Min Hwa, Gary, Joy, Liu, Chengyu, Dubois, Wendy, Hoover, Shelley B., Jiang, Shunlin, Marrogi, Eryney, Mock, Beverly, Simpson, R. Mark, Huang, Jing

Source: In Stem Cell Reports 6 June 2017 8(6):1630-1644

The 16-KDa α -Crystallin (Acr) Protein of Mycobacterium tuberculosis is Required for Growth in Macrophages

Authors: Yuan, Ying, Crane, Deborah D., Simpson, R. Mark, Zhu, Yaqi, Hickey, Mark J., Sherman, David R., Barry, Clifton E.

Source: Proceedings of the National Academy of Sciences of the United States of America, 1998 Aug 01. 95(16), 9578-9583.

Access URL: https://www.jstor.org/stable/45517

Oncogenesis driven by the Ras/Raf pathway requires the SUMO E2 ligase Ubc9

Authors: Yu, Bing, Swatkoski, Stephen, Holly, Alesia, Lee, Liam C., Giroux, Valentin, Lee, Chih-Shia, Hsu, Dennis, Jordan, L. Smith, Yuen, Garmen, Yue, Junqiu, Ann, David K., Simpson, R. Mark, Creighton, Chad J., Figg, William D., Gucek, Marjan, Luo, Ji

Source: Proceedings of the National Academy of Sciences of the United States of America, 2015 Apr 01. 112(14), E1724-E1733.

Access URL: https://www.jstor.org/stable/26462525

TORC1 and class I HDAC inhibitors synergize to suppress mature B cell neoplasms

Authors: Simmons, John K., Patel, Jyoti, Michalowski, Aleksandra, Zhang, Shuling, Wei, Bih-Rong, Sullivan, Patrick, Gamache, Ben, Felsenstein, Kenneth, Kuehl, W. Michael, Simpson, R. Mark, Zingone, Adriana, Landgren, Ola, Mock, Beverly A.

Source: In Molecular Oncology March 2014 8(2):261-272

Digital pathology and image analysis augment biospecimen annotation and biobank quality assurance harmonization

Authors: Wei, Bih-Rong, Simpson, R. Mark

Source: In Clinical Biochemistry March 2014 47(4-5):274-279

In Vivo Bioluminescent Imaging of ATP-Binding Cassette Transporter-Mediated Efflux at the Blood—Brain Barrier

Authors: Bakhsheshian, Joshua, Wei, Bih-Rong, Hall, Matthew D., Simpson, R. Mark, Gottesman, Michael M.

Source: Methods in molecular biology. 1461:227-240

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN607419497&indx=1&recIds=ETOCRN607419497

Host CLIC4 expression in the tumor microenvironment is essential for breast cancer metastatic competence.

Authors: Sanchez, Vanesa C.¹, Yang, Howard H.¹, Craig-Lucas, Alayna¹, Dubois, Wendy¹, Carofino, Brandi L.¹, Lack, Justin^2,3, Dwyer, Jennifer E.¹, Simpson, R. Mark¹, Cataisson, Christophe¹, Lee, Max P.¹, Luo, Ji¹, Hunter, Kent W.¹, Yuspa, Stuart H.¹, yuspas@mail.nih.gov

Source: PLoS Genetics; 6/21/2022, Vol. 18 Issue 6, p1-27, 27p

Bioluminescent imaging of drug efflux at the blood–brain barrier mediated by the transporter ABCG2

Authors: Bakhsheshian, Joshua, Wei, Bih-Rong, Chang, Ki-Eun, Shukla, Suneet, Ambudkar, Suresh V., Simpson, R. Mark, Gottesman, Michael M., Hall, Matthew D.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2013 Dec . 110(51), 20801-20806.

Access URL: https://www.jstor.org/stable/23761634

Soluble Peptide Treatment Reverses CD8 T-Cell-Induced Disease in a Mouse Model of Spontaneous Tissue-Selective Autoimmunity

Authors: Paek, So Yeon, Miyagawa, Fumi, Zhang, Hong, Linton, Jay T., Hoover, Shelley B., Simpson, R Mark, Katz, Stephen I. ^*

Source: In Journal of Investigative Dermatology March 2012 132(3) Part 1:677-686

Mammalian Mst1 and Mst2 Kinases Play Essential Roles in Organ Size Control and Tumor Suppression

Authors: Song, Hai, Kingston, Kinglun, Topol, Lilia, Yun, Kangsun, Hu, Jianxin, Garrett, Lisa, Chen, Yongbin, Park, Ogyi, Chang, Jia, Simpson, R. Mark, Wang, Cun-Yu, Gao, Bin, Jiang, Jin, Yang, Yingzi, Tabin, Clifford J.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2010 Jan 01. 107(4), 1431-1436.

Access URL: https://www.jstor.org/stable/40536345

Genetic Evidence for the Role of Erk Activation in a Lymphoproliferative Disease of Mice

Authors: Miyaji, Michihiko, Kortum, Robert L., Surana, Rishi, Li, Wenmei, Woolard, Kevin D., Simpson, R. Mark, Samelson, Lawrence E., Sommers, Connie L., Weiss, Arthur

Source: Proceedings of the National Academy of Sciences of the United States of America, 2009 Aug . 106(34), 14502-14507.

Access URL: https://www.jstor.org/stable/40484450

Prostate Epithelial Pten/TP53 Loss Leads to Transformation of Multipotential Progenitors and Epithelial to Mesenchymal Transition

Authors: Martin, Philip, Liu, Yen-Nien, Pierce, Rachel, Abou-Kheir, Wassim, Casey, Orla, Seng, Victoria, Camacho, Daniel, Simpson, R. Mark, Kelly, Kathleen

Source: In The American Journal of Pathology 2011 179(1):422-435

Mass spectrometry in cancer biomarker research: a case for immunodepletion of abundant blood-derived proteins from clinical tissue specimens

Authors: Prieto, DaRue A, Johann, Donald J, Wei, Bih-Rong, Ye, Xiaoying, Chan, King C, Nissley, Dwight V, Simpson, R Mark, Citrin, Deborah E, Mackall, Crystal L, Linehan, W Marston, Blonder, Josip

Source: Biomarkers in medicine. 8(2):269-286

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100115564234.0x000001&indx=1&recIds=ETOCvdc_100115564234.0x000001

Experimental Perinatal Transmission of Human Immunodeficiency Virus Type 1 by Passage of Infected T Cells

Authors: Simpson, R. Mark, Hubbard, Beth Schmidt, Zhao, Tong Mao, Kindt, Thomas J.

Source: The Journal of Infectious Diseases, 1997 Jun 01. 175(6), 1337-1343.

Access URL: https://www.jstor.org/stable/30132350