Differential Recognition Preferences of the Three Src Homology 3 (SH3) Domains from the Adaptor CD2-associated Protein (CD2AP) and Direct Association with Ras and Rab Interactor 3 (RIN3)

Authors: Rouka, Evgenia, Simister, Philip C., Janning, Melanie, Kumbrink, Joerg, Konstantinou, Tassos, Muniz, João R.C., Joshi, Dhira, O'Reilly, Nicola, Volkmer, Rudolf ^**, Ritter, Brigitte, Knapp, Stefan, von Delft, Frank, Kirsch, Kathrin H., Feller, Stephan M.

Source: In Journal of Biological Chemistry 16 October 2015 290(42):25275-25292

MAPK-induced Gab1 translocation to the plasma membrane depends on a regulated intramolecular switch

Authors: Wolf, Alexandra, Eulenfeld, René, Bongartz, Hannes, Hessenkemper, Wiebke, Simister, Philip C., Lievens, Sam, Tavernier, Jan, Feller, Stephan M., Schaper, Fred

Source: In Cellular Signalling February 2015 27(2):340-352

Conformational Recognition of an Intrinsically Disordered Protein

Authors: Krieger, James M., Fusco, Giuliana, Lewitzky, Marc, Simister, Philip C., Marchant, Jan, Camilloni, Carlo, Feller, Stephan M., De Simone, Alfonso

Source: In Biophysical Journal 15 April 2014 106(8):1771-1779

Novel inhibitors of a Grb2 SH3C domain interaction identified by a virtual screen

Authors: Simister, Philip C., Luccarelli, James, Thompson, Sam, Appella, Daniel H., Feller, Stephan M., Hamilton, Andrew D.

Source: In Bioorganic & Medicinal Chemistry 15 July 2013 21(14):4027-4033

A novel FRET peptide assay reveals efficient Helicobacter pylori HtrA inhibition through zinc and copper binding

Authors: Bernegger, Sabine, Brunner, Cyrill, Vizovišek, Matej, Fonovic, Marko, Cuciniello, Gaetano, Giordano, Flavia, Stanojlovic, Vesna, Jarzab, Miroslaw, Simister, Philip, Feller, Stephan M., Obermeyer, Gerhard, Posselt, Gernot, Turk, Boris, Cabrele, Chiara, Schneider, Gisbert, Wessler, Silja

Source: Scientific reports. 10(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100174583465.0x000001&indx=1&recIds=ETOCvdc_100174583465.0x000001

Beyond ‘furballs’ and ‘dumpling soups’ – towards a molecular architecture of signaling complexes and networks

Authors: Lewitzky, Marc, Simister, Philip C., Feller, Stephan M.

Source: In FEBS Letters 14 August 2012 586(17):2740-2750

An Objective Assessment of Conformational Variability in Complexes of Hepatitis C Virus Polymerase with Non-Nucleoside Inhibitors

Authors: Caillet-Saguy, Célia ^†, Simister, Philip C. ^†, Bressanelli, Stéphane

Source: In Journal of Molecular Biology 2011 414(3):370-384

Further Insights into the Roles of GTP and the C Terminus of the Hepatitis C Virus Polymerase in the Initiation of RNA Synthesis

Authors: Harrus, Déborah, Ahmed-El-Sayed, Neveen, Simister, Philip C., Miller, Steve, Triconnet, Martine, Hagedorn, Curt H., Mahias, Kathleen, Rey, Félix A., Astier-Gin, Thérèse, Bressanelli, Stéphane

Source: In Journal of Biological Chemistry 22 October 2010 285(43):32906-32918

Distinct Binding Modes of Two Epitopes in Gab2 that Interact with the SH3C Domain of Grb2

Authors: Harkiolaki, Maria, Tsirka, Theodora, Lewitzky, Marc, Simister, Philip C., Joshi, Dhira, Bird, Louise E., Jones, E. Yvonne, O'Reilly, Nicola, Feller, Stephan M.

Source: In Structure 10 June 2009 17(6):809-822

Interactions between Conserved Domains within Homodimers in the BIG1, BIG2, and GBF1 Arf Guanine Nucleotide Exchange Factors

Authors: Ramaen, Odile, Joubert, Alexandra, Simister, Philip, Belgareh-Touzé, Naïma, Olivares-Sanchez, Maria Conception, Zeeh, Jean-Christophe, Chantalat, Sophie, Golinelli-Cohen, Marie-Pierre, Jackson, Catherine L., Biou, Valérie, Cherfils, Jacqueline

Source: In Journal of Biological Chemistry 28 September 2007 282(39):28834-28842

ID: 58

Authors: Hessenkemper, Wiebke, Bongartz, Hannes, Fritsch, Johannes, Wolf, Alexandra, Eulenfeld, René, Simister, Philip C., Feller, Stephan M., Schaper, Fred

Source: Cytokine. 76(1):75-75

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100029286676.0x000001&indx=1&recIds=ETOCvdc_100029286676.0x000001

ID: 79

Authors: Bongartz, Hannes, Hessenkemper, Wiebke, Wolf, Alexandra, Eulenfeld, René, Simister, Philip C., Behrmann, Iris, Tavernier, Jan, Feller, Stephan M., Haan, Claude, Schaper, Fred

Source: Cytokine. 76(1):80-80

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100029272101.0x000001&indx=1&recIds=ETOCvdc_100029272101.0x000001

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ID: 79: Constitutive membrane binding of the multi-site docking protein Gab1 in JAK2-V617F expressing cells

Authors: Bongartz, Hannes, Hessenkemper, Wiebke, Wolf, Alexandra, Eulenfeld, René, Simister, Philip C., Behrmann, Iris, Tavernier, Jan, Feller, Stephan M., Haan, Claude, Schaper, Fred

Source: In Cytokine November 2015 76(1):80-80

ID: 58: Involvement of MAPK- and PI3K-pathway in Gab1 translocation and phosphorylation

Authors: Hessenkemper, Wiebke, Bongartz, Hannes, Fritsch, Johannes, Wolf, Alexandra, Eulenfeld, René, Simister, Philip C., Feller, Stephan M., Schaper, Fred

Source: In Cytokine November 2015 76(1):75-75

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