Phocaeicola vulgatus shapes the long-term growth dynamics and evolutionary adaptations of Clostridioides difficile

Authors: Sulaiman, Jordy Evan ¹, Thompson, Jaron ², Cheung, Pak Lun Kevin ³, Qian, Yili ¹, Mill, Jericha ¹, James, Isabella ⁴, Im, Hanhyeok ⁵, Vivas, Eugenio I. ^{6, 7}, Simcox, Judith ⁸, Venturelli, Ophelia S. ^{1, 2, 5, 6, 9, 10, ∗}

Source: In Cell Host & Microbe 8 January 2025 33(1):42-58

Diabetes mellitus—Progress and opportunities in the evolving epidemic

Authors: Abel, E. Dale, Gloyn, Anna L., Evans-Molina, Carmella, Joseph, Joshua J., Misra, Shivani, Pajvani, Utpal B., Simcox, Judith, Susztak, Katalin, Drucker, Daniel J.

Source: In Cell 25 July 2024 187(15):3789-3820

Dietary restriction of isoleucine increases healthspan and lifespan of genetically heterogeneous mice

Authors: Green, Cara L., Trautman, Michaela E., Chaiyakul, Krittisak, Jain, Raghav, Alam, Yasmine H., Babygirija, Reji, Pak, Heidi H., Sonsalla, Michelle M., Calubag, Mariah F., Yeh, Chung-Yang, Bleicher, Anneliese, Novak, Grace, Liu, Teresa T., Newman, Sarah, Ricke, Will A., Matkowskyj, Kristina A., Ong, Irene M., Jang, Cholsoon, Simcox, Judith, Lamming, Dudley W.

Source: In Cell Metabolism 7 November 2023 35(11):1976-1995

Determination of tissue contributions to the circulating lipid pool in cold exposure via systematic assessment of lipid profiles

Authors: Jain, Raghav, Wade, Gina, Ong, Irene, Chaurasia, Bhagirath, Simcox, Judith

Source: In Journal of Lipid Research July 2022 63(7)

The central moTOR of metabolism

Authors: Simcox, Judith, Lamming, Dudley W.

Source: In Developmental Cell 28 March 2022 57(6):691-706

Sex and genetic background define the metabolic, physiologic, and molecular response to protein restriction

Authors: Green, Cara L., Pak, Heidi H., Richardson, Nicole E., Flores, Victoria, Yu, Deyang, Tomasiewicz, Jay L., Dumas, Sabrina N., Kredell, Katherine, Fan, Jesse W., Kirsh, Charlie, Chaiyakul, Krittisak, Murphy, Michaela E., Babygirija, Reji, Barrett-Wilt, Gregory A., Rabinowitz, Joshua, Ong, Irene M., Jang, Cholsoon, Simcox, Judith, Lamming, Dudley W.

Source: In Cell Metabolism 1 February 2022 34(2):209-226

SON-light activation of glucose regulation

Authors: Geoghegan, Gisela, Simcox, Judith

Source: Cell. 186(2):238-240

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100193665720.0x000001&indx=1&recIds=ETOCvdc_100193665720.0x000001

Aging adipose: Depot location dictates age-associated expansion and dysfunction

Authors: Von Bank, Helaina, Kirsh, Charlie, Simcox, Judith ^*

Source: In Ageing Research Reviews May 2021 67

The role of ATP citrate lyase in myelin formation and maintenance.

Authors: Schneider, Andrew, Won, Seongsik, Armstrong, Eric A., Cooper, Aaron J., Suresh, Amulya, Rivera, Rachell, Barrett‐Wilt, Gregory, Denu, John M., Simcox, Judith A., Svaren, John

Source: Glia; Jan2025, Vol. 73 Issue 1, p105-121, 17p

Systemic analysis shows that cold exposure modulates triglyceride accumulation and phospholipid distribution in mice.

Authors: James, Isabella, Jain, Raghav, Wade, Gina, Stevenson, Philip C., Koulman, Albert, Simcox, Judith, Furse, Samuel

Source: PLoS ONE; 11/7/2024, Vol. 19 Issue 11, p1-17, 17p

Subject Terms: LIPID metabolism, LIPIDOMICS, ENVIRONMENTAL exposure, FATTY acids, ENERGY storage

Igniting adipocyte thermogenesis

Authors: Jain, Raghav, Simcox, Judith

Source: Cell. 185(6):941-943

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100161580100.0x000001&indx=1&recIds=ETOCvdc_100161580100.0x000001

Targeted deletion of Tcf7l2 in adipocytes promotes adipocyte hypertrophy and impaired glucose metabolism

Authors: Geoghegan, Gisela, Simcox, Judith, Seldin, Marcus M., Parnell, Timothy J., Stubben, Chris, Just, Steven, Begaye, Lori, Lusis, Aldons J., Villanueva, Claudio J.

Source: In Molecular Metabolism June 2019 24:44-63

Neutral sphingomyelinase regulates mechanotransduction in human engineered cardiac tissues and mouse hearts.

Authors: Turner, Daniel G. P., De Lange, Willem J., Zhu, Yanlong, Coe, Christopher L., Simcox, Judith, Ge, Ying, Kamp, Timothy J., Ralphe, J. Carter, Glukhov, Alexey V.

Source: Journal of Physiology; Sep2024, Vol. 602 Issue 18, p4387-4407, 21p

Subject Terms: SPHINGOMYELINASE, HYPERTENSION, PLURIPOTENT stem cells, CAVEOLAE, CERAMIDES

Drosophila HNF4 Directs a Switch in Lipid Metabolism that Supports the Transition to Adulthood

Authors: Storelli, Gilles, Nam, Hyuck-Jin, Simcox, Judith, Villanueva, Claudio J., Thummel, Carl S.

Source: In Developmental Cell 28 January 2019 48(2):200-214

Liver-specific deletion of Agpat5 protects against liquid sucrose-induced hyperinsulinemia and glucose intolerance

Authors: Michorowska, Sylwia, Vogel, Kara R., Jain, Raghav, St Clair, Samantha L., Simcox, Judith A., Parks, Brian W.

Source: In Biochemical and Biophysical Research Communications 31 December 2024 741

Lipid signatures of chronic pain in female adolescents with and without obesity.

Authors: Gonzalez, Paula A.¹ (AUTHOR), Simcox, Judith¹ (AUTHOR), Raff, Hershel^2,3 (AUTHOR), Wade, Gina¹ (AUTHOR), Von Bank, Helaina¹ (AUTHOR), Weisman, Steven^4,5 (AUTHOR), Hainsworth, Keri^5,6 (AUTHOR) khainsworth@chw.org

Source: Lipids in Health & Disease. 8/30/2022, Vol. 21 Issue 1, p1-12. 12p.

Subject Terms: *ADOLESCENT obesity, *TEENAGE girls, *CHRONIC pain, *BLOOD lipids, *LIPIDS, *INSULIN receptors, *MEMBRANE lipids

Loss of TLE3 promotes the mitochondrial program in beige adipocytes and improves glucose metabolism

Authors: Pearson, Stephanie, Loft, Anne, Rajbhandari, Prashant, Simcox, Judith, Lee, Sanghoon, Tontonoz, Peter, Mandrup, Susanne, Villanueva, Claudio J.

Source: Genes & development. 33(13/14):747-762

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN620772171&indx=1&recIds=ETOCRN620772171

Mitochondrial cardiomyopathies feature increased uptake and diminished efflux of mitochondrial calcium

Authors: Sommakia, Salah, Houlihan, Patrick R., Deane, Sadiki S., Simcox, Judith A., Torres, Natalia S., Jeong, Mi-Young, Winge, Dennis R., Villanueva, Claudio J., Chaudhuri, Dipayan

Source: In Journal of Molecular and Cellular Cardiology December 2017 113:22-32

Global Analysis of Plasma Lipids Identifies Liver-Derived Acylcarnitines as a Fuel Source for Brown Fat Thermogenesis

Authors: Simcox, Judith, Geoghegan, Gisela, Maschek, John Alan, Bensard, Claire L., Pasquali, Marzia, Miao, Ren, Lee, Sanghoon, Jiang, Lei, Huck, Ian, Kershaw, Erin E., Donato, Anthony J., Apte, Udayan, Longo, Nicola, Rutter, Jared, Schreiber, Renate, Zechner, Rudolf, Cox, James, Villanueva, Claudio J.

Source: In Cell Metabolism 5 September 2017 26(3):509-522

Lipidomics identifies novel circulating markers of CVD risk in African American and Caucasian women

Authors: Gonzalez, Paula, Jain, Raghav, Coe, Chris, Ryff, Carol, King, Camille, Bersh, Andy, Malecki, Kristen, Simcox, Judith

Source: FASEB journal. 36

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100196448249.0x000001&indx=1&recIds=ETOCvdc_100196448249.0x000001