The oncogenic axis YAP/MYC/EZH2 impairs PTEN tumor suppression activity enhancing lung tumorigenicity

Authors: Federica Lo Sardo, Chiara Turco, Beatrice Messina, Andrea Sacconi, Francesca Romana Auciello, Claudio Pulito, Sabrina Strano, Sima Lev, Giovanni Blandino

Source: Cell Death Discovery, Vol 10, Iss 1, Pp 1-13 (2024)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282, Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/2058-7716

Access URL: https://doaj.org/article/08430c12a9f548ffa6351d4edeaf6e1b

Targeting of mutant-p53 and MYC as a novel strategy to inhibit oncogenic SPAG5 activity in triple negative breast cancer

Authors: Valeria Canu, Sebastiano Vaccarella, Andrea Sacconi, Claudio Pulito, Frauke Goeman, Matteo Pallocca, Daniela Rutigliano, Sima Lev, Sabrina Strano, Giovanni Blandino

Source: Cell Death and Disease, Vol 15, Iss 8, Pp 1-15 (2024)

Subject Terms: Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/2041-4889

Access URL: https://doaj.org/article/5435e8c8e2ce4120ac48f56e3d60ac59

A snapshot into the transcriptomic landscape of apoptosis and ferroptosis in cancer

Authors: Yaron Vinik, Sima Lev

Source: Cell Death and Disease, Vol 15, Iss 5, Pp 1-4 (2024)

Subject Terms: Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/2041-4889

Access URL: https://doaj.org/article/ce156865b75c4eaba660226089f74d33

Ferroptosis in health and disease

Authors: Carsten Berndt, Hamed Alborzinia, Vera Skafar Amen, Scott Ayton, Uladzimir Barayeu, Alexander Bartelt, Hülya Bayir, Christina M. Bebber, Kivanc Birsoy, Jan P. Böttcher, Simone Brabletz, Thomas Brabletz, Ashley R. Brown, Bernhard Brüne, Giorgia Bulli, Alix Bruneau, Quan Chen, Gina M. DeNicola, Tobias P. Dick, Ayelén Distéfano, Scott J. Dixon, Jan B. Engler, Julia Esser-von Bieren, Maria Fedorova, José Pedro Friedmann Angeli, Manuel A. Friese, Dominic C. Fuhrmann, Ana J. García-Sáez, Karolina Garbowicz, Magdalena Götz, Wei Gu, Linda Hammerich, Behrouz Hassannia, Xuejun Jiang, Aicha Jeridi, Yun Pyo Kang, Valerian E. Kagan, David B. Konrad, Stefan Kotschi, Peng Lei, Marlène Le Tertre, Sima Lev, Deguang Liang, Andreas Linkermann, Carolin Lohr, Svenja Lorenz, Tom Luedde, Axel Methner, Bernhard Michalke, Anna V. Milton, Junxia Min, Eikan Mishima, Sebastian Müller, Hozumi Motohashi, Martina U. Muckenthaler, Shohei Murakami, James A. Olzmann, Gabriela Pagnussat, Zijan Pan, Thales Papagiannakopoulos, Lohans Pedrera Puentes, Derek A. Pratt, Bettina Proneth, Lukas Ramsauer, Raphael Rodriguez, Yoshiro Saito, Felix Schmidt, Carina Schmitt, Almut Schulze, Annemarie Schwab, Anna Schwantes, Mariluz Soula, Benedikt Spitzlberger, Brent R. Stockwell, Leonie Thewes, Oliver Thorn-Seshold, Shinya Toyokuni, Wulf Tonnus, Andreas Trumpp, Peter Vandenabeele, Tom Vanden Berghe, Vivek Venkataramani, Felix C.E. Vogel, Silvia von Karstedt, Fudi Wang, Frank Westermann, Chantal Wientjens, Christoph Wilhelm, Michele Wölk, Katherine Wu, Xin Yang, Fan Yu, Yilong Zou, Marcus Conrad

Source: Redox Biology, Vol 75, Iss , Pp 103211- (2024)

Subject Terms: Cell death, Lipid peroxidation, Iron, Ischemia/reperfusion, Cancer, Neurodegeneration, Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213231724001897; https://doaj.org/toc/2213-2317

Access URL: https://doaj.org/article/704bf377a6004407992c3cd92011cf30

Programming a Ferroptosis‐to‐Apoptosis Transition Landscape Revealed Ferroptosis Biomarkers and Repressors for Cancer Therapy

Authors: Yaron Vinik, Avi Maimon, Vinay Dubey, Harsha Raj, Ifat Abramovitch, Sergey Malitsky, Maxim Itkin, Avi Ma'ayan, Frank Westermann, Eyal Gottlieb, Eytan Ruppin, Sima Lev

Source: Advanced Science, Vol 11, Iss 17, Pp n/a-n/a (2024)

Subject Terms: apoptosis, biomarkers, breast cancer, classification signature, cancer therapy, ferroptosis, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2198-3844

Access URL: https://doaj.org/article/1d69ea75930a43df95571ed9b6c71f4a

Mouse Modeling Dissecting Macrophage–Breast Cancer Communication Uncovered Roles of PYK2 in Macrophage Recruitment and Breast Tumorigenesis

Authors: Anna‐Katharina Müller, Ulrike A. Köhler, Sébastien Trzebanski, Yaron Vinik, Harsha Mohan Raj, Jean‐Antoine Girault, Nir Ben‐Chetrit, Antonio Maraver, Steffen Jung, Sima Lev

Source: Advanced Science, Vol 9, Iss 9, Pp n/a-n/a (2022)

Subject Terms: breast cancer, crosstalk signaling, Notch1, PYK2, tumor‐associated macrophages, tumor microenvironment, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2198-3844

Access URL: https://doaj.org/article/36929aef80e942ad9b61fcc1472add8a

Modeling Heterogeneity of Triple‐Negative Breast Cancer Uncovers a Novel Combinatorial Treatment Overcoming Primary Drug Resistance

Authors: Fabienne Lamballe, Fahmida Ahmad, Yaron Vinik, Olivier Castellanet, Fabrice Daian, Anna‐Katharina Müller, Ulrike A. Köhler, Anne‐Laure Bailly, Emmanuelle Josselin, Rémy Castellano, Christelle Cayrou, Emmanuelle Charafe‐Jauffret, Gordon B. Mills, Vincent Géli, Jean‐Paul Borg, Sima Lev, Flavio Maina

Source: Advanced Science, Vol 8, Iss 3, Pp n/a-n/a (2021)

Subject Terms: BCL‐XL, cancer mouse model, drug resistance, MET, signaling reprogramming, triple‐negative breast cancer, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2198-3844

Access URL: https://doaj.org/article/fdcfab7683c2492fb8717fe04289a634

Mammalian PITPs at the Golgi and ER-Golgi Membrane Contact Sites

Authors: Shamshad Cockcroft, Sima Lev

Source: Contact, Vol 3 (2020)

Subject Terms: Biology (General), QH301-705.5, Biochemistry, QD415-436

File Description: electronic resource

Relation: https://doaj.org/toc/2515-2564

Access URL: https://doaj.org/article/2832c8855b5d4a5a8044e81aa2688568

Lipid Transfer Proteins and Membrane Contact Sites in Human Cancer

Authors: Diego Peretti, SoHui Kim, Roberta Tufi, Sima Lev

Source: Frontiers in Cell and Developmental Biology, Vol 7 (2020)

Subject Terms: LTPs, MCSs, cancer, calcium, lipids, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fcell.2019.00371/full; https://doaj.org/toc/2296-634X

Access URL: https://doaj.org/article/4f573c8a47734640815abca2cd3ebf77

MicroRNA-182 targets SMAD7 to potentiate TGFβ-induced epithelial-mesenchymal transition and metastasis of cancer cells

Authors: Jingyi Yu, Rong Lei, Xueqian Zhuang, Xiaoxun Li, Gang Li, Sima Lev, Miguel F. Segura, Xue Zhang, Guohong Hu

Source: Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/ec0353b3c0b54b89a9b62aad167220c3

Systems modelling of the EGFR-PYK2-c-Met interaction network predicts and prioritizes synergistic drug combinations for triple-negative breast cancer.

Authors: Sung-Young Shin, Anna-Katharina Müller, Nandini Verma, Sima Lev, Lan K Nguyen

Source: PLoS Computational Biology, Vol 14, Iss 6, p e1006192 (2018)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1006192&type=printable; https://doaj.org/toc/1553-734X; https://doaj.org/toc/1553-7358

Access URL: https://doaj.org/article/07401823edae44248a870331e11b7243

VAMP-associated protein B (VAPB) promotes breast tumor growth by modulation of Akt activity.

Authors: Meghana Rao, Wenqiang Song, Aixiang Jiang, Yu Shyr, Sima Lev, David Greenstein, Dana Brantley-Sieders, Jin Chen

Source: PLoS ONE, Vol 7, Iss 10, p e46281 (2012)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3462209?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/c456849875e644b7b54b3b484434ae20

Professional identity of teachers as a component of university corporate culture

Authors: Flura Zueva, Sima Levina, Irina Likhodumova, Irina Kilmasova

Source: Política e Gestão Educacional, Vol 26, Iss 00 (2022)

Subject Terms: Corporate cultureCorporate culture, Professional identity, Educational environment, Teacher, Educational organization, Education (General), L7-991, Special aspects of education, LC8-6691

File Description: electronic resource

Relation: https://periodicos.fclar.unesp.br/rpge/article/view/17336; https://doaj.org/toc/1519-9029

Access URL: https://doaj.org/article/479c4f09a5f6461a85a0e432f702b3ed

The COG complex interacts with multiple Golgi SNAREs and enhances fusogenic assembly of SNARE complexes.

Authors: Laufman, Orly, WanJin Hong, Sima Lev

Source: Journal of Cell Science; 3/15/2013, Vol. 126 Issue 6, p1506-1516, 11p

Subject Terms: GOLGI apparatus, IMMUNOPRECIPITATION, MOLECULAR self-assembly, ENDOSOMES, PROTEIN-protein interactions, GENETIC regulation

This result is not displayed to guests.
Login for full access.