Brain alarm by self-extracellular nucleic acids: from neuroinflammation to neurodegeneration

Authors: Reiner Kunze, Silvia Fischer, Hugo H. Marti, Klaus T. Preissner

Source: Journal of Biomedical Science, Vol 30, Iss 1, Pp 1-50 (2023)

Subject Terms: Danger associated molecular patterns, Extracellular ribosomal RNA, Extracellular mitochondrial DNA, Non-coding RNAs, Neutrophil extracellular traps, Pattern recognition receptors, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1423-0127

Access URL: https://doaj.org/article/a59c18679bc040ea8e7b881da8bca058

Self-extracellular RNA promotes pro-inflammatory response of astrocytes to exogenous and endogenous danger signals

Authors: Silvia Fischer, Emil Nasyrov, Monika Brosien, Klaus T. Preissner, Hugo H. Marti, Reiner Kunze

Source: Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-13 (2021)

Subject Terms: Extracellular RNA, Astrocyte, Inflammation, Stroke, Ischemia/reperfusion, PAMP, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/1742-2094

Access URL: https://doaj.org/article/0caa6a0917ab42cbacfdd3aca7802f56

RNase A Inhibits Formation of Neutrophil Extracellular Traps in Subarachnoid Hemorrhage

Authors: Anton Früh, Katharina Tielking, Felix Schoknecht, Shuheng Liu, Ulf C. Schneider, Silvia Fischer, Peter Vajkoczy, Ran Xu

Source: Frontiers in Physiology, Vol 12 (2021)

Subject Terms: neutrophil extracellular traps, neutrophils, subarachnoid hemorrhage, hemorrhagic stroke, neuroinflammation, innate immune response, Physiology, QP1-981

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphys.2021.724611/full; https://doaj.org/toc/1664-042X

Access URL: https://doaj.org/article/ef33db81546542e58a8df2060127ab02

State of the Art of Innate Immunity—An Overview

Authors: Silvia Fischer, Elisabeth Deindl

Source: Cells, Vol 11, Iss 17, p 2705 (2022)

Subject Terms: n/a, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/11/17/2705; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/d2e918413a8f4036a6115080a8634a21

Extracellular RNA as a Versatile DAMP and Alarm Signal That Influences Leukocyte Recruitment in Inflammation and Infection

Authors: Klaus T. Preissner, Silvia Fischer, Elisabeth Deindl

Source: Frontiers in Cell and Developmental Biology, Vol 8 (2020)

Subject Terms: extracellular nucleic acids, danger-associated molecular patterns, inflammatory vascular diseases, arteriogenesis, endothelial cells, virus infection, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2020.619221/full; https://doaj.org/toc/2296-634X

Access URL: https://doaj.org/article/582b232336164cb7a1c7d10de9620396

Extracellular Ribosomal RNA Acts Synergistically with Toll-like Receptor 2 Agonists to Promote Inflammation

Authors: Karsten Grote, Marina Nicolai, Uwe Schubert, Bernhard Schieffer, Christian Troidl, Klaus T. Preissner, Stefan Bauer, Silvia Fischer

Source: Cells, Vol 11, Iss 9, p 1440 (2022)

Subject Terms: extracellular RNA, inflammation, cytokines, macrophages, endothelial cells, toll-like receptors, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/11/9/1440; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/fe007447e3ff4d5e90ce0863e0c0cca5

Polysialic acid is released by human umbilical vein endothelial cells (HUVEC) in vitro

Authors: Sebastian Strubl, Uwe Schubert, Andrea Kühnle, Alexander Rebl, Negah Ahmadvand, Silvia Fischer, Klaus T. Preissner, Sebastian P. Galuska

Source: Cell & Bioscience, Vol 8, Iss 1, Pp 1-9 (2018)

Subject Terms: Human umbilical vein endothelial cells, Polysialic acid, Vascular endothelial growth factor, Biotechnology, TP248.13-248.65, Biology (General), QH301-705.5, Biochemistry, QD415-436

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13578-018-0262-y; https://doaj.org/toc/2045-3701

Access URL: https://doaj.org/article/d193c312727b4b15ae95bce8147d42b9

Extracellular RNA in Central Nervous System Pathologies

Authors: Katharina Tielking, Silvia Fischer, Klaus T. Preissner, Peter Vajkoczy, Ran Xu

Source: Frontiers in Molecular Neuroscience, Vol 12 (2019)

Subject Terms: extracellular RNA, extracellular vesicles, neuroinflammation, CNS pathologies, glioblastoma multiforme, brain metastasis, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fnmol.2019.00254/full; https://doaj.org/toc/1662-5099

Access URL: https://doaj.org/article/e98d4a4039d944f9b82a3b0c01e217dd

Characterization of RNA in Extracellular Vesicles

Authors: Silvia Fischer, Elisabeth Deindl

Source: Applied Sciences, Vol 11, Iss 16, p 7520 (2021)

Subject Terms: extracellular vesicles, exosomes, extracellular RNA, Technology, Engineering (General). Civil engineering (General), TA1-2040, Biology (General), QH301-705.5, Physics, QC1-999, Chemistry, QD1-999

File Description: electronic resource

Relation: https://www.mdpi.com/2076-3417/11/16/7520; https://doaj.org/toc/2076-3417

Access URL: https://doaj.org/article/90c04ca80d3f472bba15cdfe86e2fce7

Absence of Cold-Inducible RNA-Binding Protein (CIRP) Promotes Angiogenesis and Regeneration of Ischemic Tissue by Inducing M2-Like Macrophage Polarization

Authors: Matthias Kübler, Sebastian Beck, Silvia Fischer, Philipp Götz, Konda Kumaraswami, Hellen Ishikawa-Ankerhold, Manuel Lasch, Elisabeth Deindl

Source: Biomedicines, Vol 9, Iss 4, p 395 (2021)

Subject Terms: angiogenesis, cold-inducible RNA-binding protein, CIRP, CIRBP, neutrophil extracellular traps, NETs, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2227-9059/9/4/395; https://doaj.org/toc/2227-9059

Access URL: https://doaj.org/article/76e71e6b9cdb4e23bda2e2d0e6ae6029

Perivascular Mast Cells Govern Shear Stress-Induced Arteriogenesis by Orchestrating Leukocyte Function

Authors: Omary Chillo, Eike Christian Kleinert, Thomas Lautz, Manuel Lasch, Judith-Irina Pagel, Yvonn Heun, Kerstin Troidl, Silvia Fischer, Amelia Caballero-Martinez, Annika Mauer, Angela R.M. Kurz, Gerald Assmann, Markus Rehberg, Sandip M. Kanse, Bernhard Nieswandt, Barbara Walzog, Christoph A. Reichel, Hanna Mannell, Klaus T. Preissner, Elisabeth Deindl

Source: Cell Reports, Vol 16, Iss 8, Pp 2197-2207 (2016)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124716309585; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/29290659cd284108ba015bffadecf23e

Targeting of Extracellular RNA Reduces Edema Formation and Infarct Size and Improves Survival After Myocardial Infarction in Mice

Authors: Philipp Stieger, Jan‐Marcus Daniel, Christiane Thölen, Jochen Dutzmann, Kai Knöpp, Dursun Gündüz, Muhammad Aslam, Marian Kampschulte, Alexander Langheinrich, Silvia Fischer, Hector Cabrera‐Fuentes, Yong Wang, Kai C. Wollert, Johann Bauersachs, Rüdiger Braun‐Dullaeus, Klaus T. Preissner, Daniel G. Sedding

Source: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 6 (2017)

Subject Terms: edema, extracellular RNA, myocardial infarction, RNase‐1, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://doaj.org/toc/2047-9980

Access URL: https://doaj.org/article/72b1cd72b9124f03a6b28bb52fe7293a

Self-extracellular RNA acts in synergy with exogenous danger signals to promote inflammation.

Authors: Frederik Noll, Jonas Behnke, Silke Leiting, Kerstin Troidl, Gustavo Teixeira Alves, Holger Müller-Redetzky, Klaus T Preissner, Silvia Fischer

Source: PLoS ONE, Vol 12, Iss 12, p e0190002 (2017)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5738100?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/1ff4ae6d2e9440eb9de04889d86b1275

The expression and localization of RNase and RNase inhibitor in blood cells and vascular endothelial cells in homeostasis of the vascular system.

Authors: Ayaka Ohashi, Aya Murata, Yuichiro Cho, Shizuko Ichinose, Yuriko Sakamaki, Miwako Nishio, Osamu Hoshi, Silvia Fischer, Klaus T Preissner, Takatoshi Koyama

Source: PLoS ONE, Vol 12, Iss 3, p e0174237 (2017)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5362223?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/ed3e3445bf6f4af99c574122be913f43

Ribonuclease (RNase) Prolongs Survival of Grafts in Experimental Heart Transplantation

Authors: Eike Kleinert, Martin C. Langenmayer, Bruno Reichart, Jana Kindermann, Barbara Griemert, Andreas Blutke, Kerstin Troidl, Tanja Mayr, Tobias Grantzow, Fatih Noyan, Jan‐Michael Abicht, Silvia Fischer, Klaus T. Preissner, Ruediger Wanke, Elisabeth Deindl, Sonja Guethoff

Source: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 5 (2016)

Subject Terms: edema, extracellular RNA, ischemia/reperfusion injury, ribonuclease, transplantation, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://doaj.org/toc/2047-9980

Access URL: https://doaj.org/article/b04da19692014e569902ca00f3570714

Structural requirements for the procoagulant activity of nucleic acids.

Authors: Julia Gansler, Miriam Jaax, Silke Leiting, Bettina Appel, Andreas Greinacher, Silvia Fischer, Klaus T Preissner

Source: PLoS ONE, Vol 7, Iss 11, p e50399 (2012)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3511531?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/7e74412a622447a1859400f9781cfdbd

Simultaneous activation of several second messengers in hypoxia-induced hyperpermeability of brain derived endothelial cells.

Authors: Silvia Fischer¹, Marion Wiesnet², Hugo H. Marti³, Dieter Renz¹, Wolfgang Schaper²

Source: Journal of Cellular Physiology. Mar2004, Vol. 198 Issue 3, p359-369. 11p.

Subject Terms: *ISCHEMIA, *EDEMA, *GROWTH factors, *LOCALIZATION theory