Cytoreductive therapy in younger adults with polycythemia vera: a meta-analysis of safety and outcomes

Authors: Chamseddine, Reem S., Savenkov, Oleksandr, Rana, Shehroz, Khalid, Mohammed, Silver, Richard T., Kucine, Nicole, Scandura, Joseph M., Abu-Zeinah, Ghaith

Source: In Blood Advances 28 May 2024 8(10):2520-2526

Incidence of blast phase in myelofibrosis according to anemia severity

Authors: Mora, Barbara, Maffioli, Margherita, Rumi, Elisa, Guglielmelli, Paola, Caramella, Marianna, Kuykendall, Andrew, Palandri, Francesca, Iurlo, Alessandra, De Stefano, Valerio, Kiladjian, Jean‐Jacques, Elli, Elena M., Polverelli, Nicola, Gotlib, Jason, Albano, Francesco, Silver, Richard T., Benevolo, Giulia, Ross, David M., Devos, Timothy, Borsani, Oscar, Barbui, Tiziano, Porta, Matteo G. Della, Bertù, Lorenza, Komrokji, Rami, Vannucchi, Alessandro M., Passamonti, Francesco

Source: EJHaem. 4(3):679-689

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100192730820.0x000001&indx=1&recIds=ETOCvdc_100192730820.0x000001

Excess mortality in younger patients with myeloproliferative neoplasms

Authors: Abu-Zeinah, Khalid, Saadeh, Khalil, Silver, Richard T., Scandura, Joseph M., Abu-Zeinah, Ghaith

Source: Leukemia & lymphoma. 64(3):725-729

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100179677109.0x000001&indx=1&recIds=ETOCvdc_100179677109.0x000001

Polycythemia vera: aspects of its current diagnosis and initial treatment

Authors: Silver, Richard T, Abu-Zeinah, Ghaith

Source: Expert review of hematology. 16(4):253-266

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100179691440.0x000001&indx=1&recIds=ETOCvdc_100179691440.0x000001

Transplant Outcomes in Myelofibrosis: Impact of Donor Type (Cord Blood Grafts Supported by CD34+ selected Cells [Haplo-Cord] Versus Matched Donors)

Authors: Ghalehsari, Nima ^{1, 3}, Castillo Tokumori, Franco ¹, Chen, Zhengming ², Liu, Marie ³, Mayer, Sebastian A. ¹, Zeinah, Ghaith Abu ¹, Shore, Tsiporah B. ¹, Ritchie, Ellen K. ¹, Silver, Richard T. ¹, Scandura, Joseph M. ¹, Roboz, Gail J. ¹, van Besien, Koen ^{1, 4}, Gomez-Arteaga, Alexandra ^{1, ⁎}

Source: In Transplantation and Cellular Therapy November 2024 30(11):1100-1100

Appropriate management of polycythaemia vera with cytoreductive drug therapy: European LeukemiaNet 2021 recommendations

Authors: Marchetti, Monia, Vannucchi, Alessandro Maria, Griesshammer, Martin, Harrison, Claire, Koschmieder, Steffen, Gisslinger, Heinz, Álvarez-Larrán, Alberto, De Stefano, Valerio, Guglielmelli, Paola, Palandri, Francesca, Passamonti, Francesco, Barosi, Giovanni, Silver, Richard T, Hehlmann, Rüdiger, Kiladjian, Jean-Jacques, Barbui, Tiziano

Source: Lancet.Haematology. 9(4):e301-e311

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100183244444.0x000001&indx=1&recIds=ETOCvdc_100183244444.0x000001

A randomized phase 3 trial of interferon-α vs hydroxyurea in polycythemia vera and essential thrombocythemia

Authors: Mascarenhas, John, Kosiorek, Heidi E., Prchal, Josef T., Rambaldi, Alessandro, Berenzon, Dmitriy, Yacoub, Abdulraheem, Harrison, Claire N., McMullin, Mary Frances, Vannucchi, Alessandro M., Ewing, Joanne, O'Connell, Casey L., Kiladjian, Jean-Jacques, Mead, Adam J., Winton, Elliott F., Leibowitz, David S., De Stefano, Valerio, Arcasoy, Murat O., Kessler, Craig M., Catchatourian, Rosalind, Rondelli, Damiano, Silver, Richard T., Bacigalupo, Andrea, Nagler, Arnon, Kremyanskaya, Marina, Levine, Max F., Arango Ossa, Juan E., McGovern, Erin, Sandy, Lonette, Salama, Mohamad E., Najfeld, Vesna, Tripodi, Joseph, Farnoud, Noushin, Penson, Alexander V., Weinberg, Rona Singer, Price, Leah, Goldberg, Judith D., Barbui, Tiziano, Marchioli, Roberto, Tognoni, Gianni, Rampal, Raajit K., Mesa, Ruben A., Dueck, Amylou C., Hoffman, Ronald

Source: Blood. 139(19):2931-2941

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100183252912.0x000001&indx=1&recIds=ETOCvdc_100183252912.0x000001

Patient-Reported Functional Outcomes in Patients With Chronic Myeloid Leukemia After Stopping Tyrosine Kinase Inhibitors

Authors: Schoenbeck, Kelly L, Atallah, Ehab, Lin, Li, Weinfurt, Kevin P, Cortes, Jorge, Deininger, Michael W N, Kota, Vamsi, Larson, Richard A, Mauro, Michael J, Oehler, Vivian G, Pinilla-Ibarz, Javier, Radich, Jerald P, Schiffer, Charles A, Shah, Neil P, Silver, Richard T, Thompson, James E, Flynn, Kathryn E

Source: Journal of the National Cancer Institute. 114(1):160-164

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100138873710.0x000001&indx=1&recIds=ETOCvdc_100138873710.0x000001

Response to pegylated interferon in a COVID‐19–positive elderly woman with primary myelofibrosis treated with ruxolitinib

Authors: Frankel, Arthur E., Reddy, Renuka, DeSuza, Kayla R., Deeb, Khaled, Carlin, Aaron F., Smith, Davey, Xie, Yushuang, Naik, Eknath, Silver, Richard T., Hasselbalch, Hans C.

Source: Clinical case reports. 9(4):2228-2235

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100121118188.0x000001&indx=1&recIds=ETOCvdc_100121118188.0x000001

Interferon-alpha for treating polycythemia vera yields improved myelofibrosis-free and overall survival

Authors: Abu-Zeinah, Ghaith, Krichevsky, Spencer, Cruz, Tatiana, Hoberman, Gabriela, Jaber, Diana, Savage, Niamh, Sosner, Claudia, Ritchie, Ellen K., Scandura, Joseph M., Silver, Richard T.

Source: Leukemia. 35(9):2592-2601

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100193005736.0x000001&indx=1&recIds=ETOCvdc_100193005736.0x000001

Outcomes for ruxolitinib only vs combination with interferon in treating patients with myelofibrosis

Authors: Erdos, Katie ¹, Alshareef, Aya ², Silver, Richard T. ¹, Scandura, Joseph M. ¹, Abu-Zeinah, Ghaith ^{1, ∗}

Source: In Blood Neoplasia January 2025

Incremental Utility of Right Ventricular Dysfunction in Patients With Myeloproliferative Neoplasm–Associated Pulmonary Hypertension

Authors: Kim, Jiwon, Krichevsky, Spencer, Xie, Lola, Palumbo, Maria Chiara, Rodriguez-Diego, Sara, Yum, Brian, Brouwer, Lillian, Silver, Richard T., Schafer, Andrew I., Ritchie, Ellen K., Yabut, Maria Mia, Sosner, Claudia, Horn, Evelyn M., Devereux, Richard B., Scandura, Joseph M., Weinsaft, Jonathan W.

Source: In Journal of the American Society of Echocardiography December 2019 32(12):1574-1585

Pegylated interferon alfa-2a for polycythemia vera or essential thrombocythemia resistant or intolerant to hydroxyurea

Authors: Yacoub, Abdulraheem, Mascarenhas, John, Kosiorek, Heidi, Prchal, Josef T., Berenzon, Dmitry, Baer, Maria R., Ritchie, Ellen, Silver, Richard T., Kessler, Craig, Winton, Elliott, Finazzi, Maria Chiara, Rambaldi, Alessandro, Vannucchi, Alessandro M., Leibowitz, David, Rondelli, Damiano, Arcasoy, Murat O., Catchatourian, Rosalind, Vadakara, Joseph, Rosti, Vittorio, Hexner, Elizabeth, Kremyanskaya, Marina, Sandy, Lonette, Tripodi, Joseph, Najfeld, Vesna, Farnoud, Noushin, Papaemmanuil, Elli, Salama, Mohamed, Singer-Weinberg, Rona, Rampal, Raajit, Goldberg, Judith D., Barbui, Tiziano, Mesa, Ruben, Dueck, Amylou C., Hoffman, Ronald

Source: In Blood 31 October 2019 134(18):1498-1509

Ruxolitinib can cause weight gain by blocking leptin signaling in the brain via JAK2/STAT3

Authors: Mollé, Nicole, Krichevsky, Spencer, Kermani, Pouneh, Silver, Richard T., Ritchie, Ellen, Scandura, Joseph M.

Source: Blood. 135(13):1062-1065

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN623378367&indx=1&recIds=ETOCRN623378367

Myelofibrosis: best practices, controversies and 2019 update

Authors: Cruz, Nicole M., Gergis, Usama, Silver, Richard T.

Source: Expert review of hematology. 13(1):71-84

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100095904010.0x000001&indx=1&recIds=ETOCvdc_100095904010.0x000001

Fedratinib in patients with myelofibrosis previously treated with ruxolitinib: An updated analysis of the JAKARTA2 study using stringent criteria for ruxolitinib failure

Authors: Harrison, Claire N., Schaap, Nicolaas, Vannucchi, Alessandro M., Kiladjian, Jean‐Jacques, Jourdan, Eric, Silver, Richard T., Schouten, Harry C., Passamonti, Francesco, Zweegman, Sonja, Talpaz, Moshe, Verstovsek, Srdan, Rose, Shelonitda, Shen, Juan, Berry, Tymara, Brownstein, Carrie, Mesa, Ruben A.

Source: American journal of hematology. 95(6):594-603

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100107684645.0x000001&indx=1&recIds=ETOCvdc_100107684645.0x000001

A randomized, double-blind, placebo-controlled phase 3 study to assess efficacy and safety of ropeginterferon alfa-2b in patients with early/lower-risk primary myelofibrosis.

Authors: Abu-Zeinah, Ghaith, Qin, Albert, Gill, Harinder, Komatsu, Norio, Mascarenhas, John, Shih, Weichung Joe, Zagrijtschuk, Oleh, Sato, Toshiaki, Shimoda, Kazuya, Silver, Richard T., Mesa, Ruben

Source: Annals of Hematology; Sep2024, Vol. 103 Issue 9, p3573-3583, 11p

Subject Terms: CLINICAL trials, MYELOPROLIFERATIVE neoplasms, GENETIC mutation, BONE marrow, PATIENT safety

MPN-193 Incidence of Blast Phase in Myelofibrosis According to Anemia Severity

Authors: Mora, Barbara, Maffioli, Margherita, Rumi, Elisa, Guglielmelli, Paola, Caramella, Marianna, Kuykendall, Andrew, Palandri, Francesca, Iurlo, Alessandra, de Stefano, Valerio, Kiladjian, Jean-Jacques, Elli, Elena M, Polverelli, Nicola, Gotlib, Jason, Albano, Francesco, Silver, Richard T, Benevolo, Giulia, Ross, David M, Devos, Timothy, Borsani, Oscar, Barbui, Tiziano, Porta, Matteo G Della, Bertú, Lorenza, Komrokji, Rami, Vannucchi, Alessandro M, Passamonti, Francesco

Source: Clinical lymphoma, myeloma & leukemia. 23(S1):S386-S387

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100196313289.0x000001&indx=1&recIds=ETOCvdc_100196313289.0x000001

Distinguishing essential thrombocythemia JAK2V617F from polycythemia vera: limitations of erythrocyte values

Authors: Silver, Richard T., Krichevsky, Spencer

Source: Haematologica. 104(11):2200-2205

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN622094895&indx=1&recIds=ETOCRN622094895

Second primary malignancies in postpolycythemia vera and postessential thrombocythemia myelofibrosis: A study on 2233 patients

Authors: Mora, Barbara, Rumi, Elisa, Guglielmelli, Paola, Barraco, Daniela, Maffioli, Margherita, Rambaldi, Alessandro, Caramella, Marianna, Komrokji, Rami, Gotlib, Jason, Kiladjian, Jean Jacques, Cervantes, Francisco, Devos, Timothy, Palandri, Francesca, Stefano, Valerio, Ruggeri, Marco, Silver, Richard T., Benevolo, Giulia, Albano, Francesco, Cavalloni, Chiara, Pietra, Daniela, Barbui, Tiziano, Rotunno, Giada, Cazzola, Mario, Vannucchi, Alessandro Maria, Giorgino, Toni, Passamonti, Francesco

Source: Cancer medicine. 8(9):4089-4092

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100087202059.0x000001&indx=1&recIds=ETOCvdc_100087202059.0x000001